KEGG   Panthera uncia (snow leopard): 125926707
Entry
125926707         CDS       T08832                                 
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
puc  Panthera uncia (snow leopard)
Pathway
puc04010  MAPK signaling pathway
puc04015  Rap1 signaling pathway
puc04218  Cellular senescence
puc04380  Osteoclast differentiation
puc04620  Toll-like receptor signaling pathway
puc04664  Fc epsilon RI signaling pathway
puc04668  TNF signaling pathway
puc04750  Inflammatory mediator regulation of TRP channels
puc04912  GnRH signaling pathway
puc04935  Growth hormone synthesis, secretion and action
puc04936  Alcoholic liver disease
puc05014  Amyotrophic lateral sclerosis
puc05022  Pathways of neurodegeneration - multiple diseases
puc05132  Salmonella infection
puc05135  Yersinia infection
puc05145  Toxoplasmosis
puc05161  Hepatitis B
puc05163  Human cytomegalovirus infection
puc05167  Kaposi sarcoma-associated herpesvirus infection
puc05169  Epstein-Barr virus infection
puc05170  Human immunodeficiency virus 1 infection
puc05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
puc05417  Lipid and atherosclerosis
puc05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:puc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    125926707
   04015 Rap1 signaling pathway
    125926707
   04668 TNF signaling pathway
    125926707
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    125926707
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    125926707
   04664 Fc epsilon RI signaling pathway
    125926707
  09152 Endocrine system
   04912 GnRH signaling pathway
    125926707
   04935 Growth hormone synthesis, secretion and action
    125926707
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    125926707
  09158 Development and regeneration
   04380 Osteoclast differentiation
    125926707
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    125926707
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    125926707
   05161 Hepatitis B
    125926707
   05163 Human cytomegalovirus infection
    125926707
   05167 Kaposi sarcoma-associated herpesvirus infection
    125926707
   05169 Epstein-Barr virus infection
    125926707
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    125926707
   05135 Yersinia infection
    125926707
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    125926707
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    125926707
   05022 Pathways of neurodegeneration - multiple diseases
    125926707
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    125926707
   05418 Fluid shear stress and atherosclerosis
    125926707
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    125926707
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:puc01001]
    125926707
Enzymes [BR:puc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     125926707
Protein kinases [BR:puc01001]
 Serine/threonine kinases: STE group
  STE7 family
   125926707
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Seadorna_VP7 Pkinase_fungal Choline_kinase Haspin_kinase CLP1_P DUF4344 APH
Other DBs
NCBI-GeneID: 125926707
NCBI-ProteinID: XP_049492376
LinkDB
Position
E1:20867655..20981809
AA seq 338 aa
MSQSKGRKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAESMPPERINPELNQKGYSV
KSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPGDKFTEEFVDFTSQCLK
KNSKERPTYPELMQHPFFTLHESKATDVASFVKLILGD
NT seq 1017 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaggaagcgaaaccctggccttaaaattccaaaagaagcattt
gaacaacctcagaccagttccacgccacctcgagacttagactccaaagcttgcatttct
attggaaatcagaactttgaggtgaaggcagatgatctggaaccaataatggaactgggg
cgaggtgcgtacggggtcgtggagaagatgcgacacgtgcccagcgggcagatcatggcg
gtgaagcggatccgggccacagtaaatagccaggagcagaaaaggctactgatggatttg
gatatttccatgaggacagtggactgtcctttcacagtcaccttttatggtgcactcttc
cgggagggtgatgtttggatttgcatggaactcatggatacatcgctagataaattctac
aaacaagtgattgacaaaggccaaacaattccagaggacatcttagggaaaatagcagtt
tctattgtaaaggcgttagaacatttacacagtaagctctctgtcattcatcgagacgtc
aagccttccaacgtgctgatcaacactctgggccaagtaaagatgtgcgattttggaatc
agtggctaccttgtagactctgtcgctaaaactattgatgcaggatgcaaaccctacatg
gccgaaagtatgccacccgaaagaataaacccagagctcaatcagaagggatatagtgtg
aagtctgacatttggagtctgggcatcacaatgattgagttggcgatccttcggtttccc
tatgactcttggggaactcccttccaacagctcaaacaggtggtagaggagccctcacca
cagctcccgggagacaagttcaccgaagagtttgttgactttacctcacagtgcttgaag
aagaattccaaagaacggccaacatatccagaacttatgcaacatccatttttcacccta
cacgaatccaaagcaacagacgtggcatcttttgtaaaattgattcttggagactaa

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