Panthera uncia (snow leopard): 125927357
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Entry
125927357 CDS
T08832
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1 isoform X1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
puc
Panthera uncia (snow leopard)
Pathway
puc04140
Autophagy - animal
puc04141
Protein processing in endoplasmic reticulum
puc04210
Apoptosis
puc04932
Non-alcoholic fatty liver disease
puc05010
Alzheimer disease
puc05012
Parkinson disease
puc05014
Amyotrophic lateral sclerosis
puc05016
Huntington disease
puc05017
Spinocerebellar ataxia
puc05022
Pathways of neurodegeneration - multiple diseases
puc05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
puc00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
125927357
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
125927357
09143 Cell growth and death
04210 Apoptosis
125927357
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
125927357
05012 Parkinson disease
125927357
05014 Amyotrophic lateral sclerosis
125927357
05016 Huntington disease
125927357
05017 Spinocerebellar ataxia
125927357
05022 Pathways of neurodegeneration - multiple diseases
125927357
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
125927357
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
125927357
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
puc01001
]
125927357
Enzymes [BR:
puc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
125927357
Protein kinases [BR:
puc01001
]
Serine/threonine kinases: Other
IRE family
125927357
BRITE hierarchy
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Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
APH
Kdo
Motif
Other DBs
NCBI-GeneID:
125927357
NCBI-ProteinID:
XP_049493601
LinkDB
All DBs
Position
E1:complement(16963832..17046981)
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AA seq
972 aa
AA seq
DB search
MPVRLLLALLLSGLGIFGSPSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDPVLQ
VPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMGKKQD
IWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYFDYA
ASLPEDDGDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRKVMHI
NVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMVHEG
VAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKSKLNYLRNYWLLIG
HHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVEQTSENAPTAVSQEVE
EKFEHAPAKPEAPVDSVLKDIATIILSTFLLIGWVAFIITYPLSMHQQQQLQHQQFQKEL
EKIQLLQQQQLPFHPPGDVAQDAELLDSSGLYSESSGTSSPSTSPRASNHSLHSSGSASR
AGASPFLEQDDEDEETSMVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPEC
FSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFAHLGLEP
ITLLQQTTSGLAHLHSLSIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVGRHSF
SRRSGVPGTEGWIAPEMLSEDCKDNPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQANI
LLGAYSLDCLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFFQDV
SDRIEKESLDGPIVKQLERGGRAVVKTDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMR
NKKHHYRELPAEVRETLGSLPDDFVRYFTSRFPHLLPHTYRAMEPCSHERLFQPYYCHEP
PELRPPVTPDAL
NT seq
2919 nt
NT seq
+upstream
nt +downstream
nt
atgccggtccggctgctgctggcgctgctgctgtccggcctcgggatttttggaagtccc
agcacagtgacacttcccgaaaccttgttgtttgtgtcaaccctggatggaagcttgcat
gctgtcagtaagaggacgggctcaatcaaatggactttaaaagaagatccggttctgcag
gttccaacgcatgtggaagagcctgccttcctcccagatcccaatgatggcagcctgtat
acacttgggggcaagaataatgaaggcctgacgaaacttccctttaccatcccagagctc
gtacaggcatccccatgccgaagttcagatggaattctctacatgggtaaaaagcaggac
atttggtatgttattgatcttctgaccggggagaagcagcagactttgtcatcggccttt
gcagacagtctctgcccatcaacctctctgctgtatctcgggcgaacagagtatacaatc
accatgtacgacaccaaaacccgcgagctccggtggaatgccacctacttcgactacgcg
gcctcactgccggaggacgacggggactacaagatgtcccactttgtgtccaacggcgat
gggctggtggtgaccgtggacagtgaatctggcgacgtcctgtggatccaaaactacgct
tcccctgtggtggccttttatgtctggcagcgggagggtctgcggaaggtgatgcacatc
aacgtcgcagtggagacgctgcgctatctgaccttcatgtctggggaggtgggccgcatc
accaagtggaagtacccgttccccaaggagacggaggccaagagcaagctgacgcccacc
ctgtatgtcgggaaatactctaccagcctgtatgcctccccctccatggtgcacgagggg
gtcgccgttgtgccccgaggcagcacacttcctttgctggaaggcccccagactgacggg
gtcaccattggggacaaaggggagtgtgtgatcacgcccagcacagacctaaagtttgac
cctgggctcaaagggaagagcaagctcaactacttgaggaactactggcttctgatagga
caccatgaaacccccctgtctgcgtctaccaagatgctggagagattccccaataatctg
cccaaacatcgagaaaatgtgattcctgccgattcagagaagaagagctttgaggaagtt
atcaacctggtcgagcagacttcagaaaacgcgcccaccgccgtttcacaggaggtggag
gagaagttcgagcatgcccccgctaagcccgaggcccccgtggactctgtgctgaaggac
atagccaccatcatcctgagcaccttcctgctcatcggctgggtggccttcatcatcacc
taccccttgagcatgcatcagcagcagcagctccagcaccagcagttccagaaggaacta
gagaaaatccagctcctgcaacagcagcagctgcccttccatccccctggggacgtggct
caggatgctgagctcctggactcgtccggcctgtactcagagagctcgggcaccagcagc
cccagcacatcccccagagcctccaaccactcgctccactccagtggctctgcctccagg
gctggtgccagccccttcctggagcaggacgatgaagatgaggaaaccagcatggtgatt
gttgggaagatctcattctgtcccaaggacgtgctgggccacggagctgagggcacgatt
gtgtaccggggcatgttcgacaaccgcgatgtggccgtcaagaggatcctccccgagtgt
ttcagtttcgcggaccgtgaggtccagctgcttcgggaatcagacgagcaccccaacgtg
attcgttacttctgcacggagagggaccggcagttccagtacattgccatcgagctgtgt
gcggccaccctgcaggagtacgtggagcagaaggacttcgcccacctcggcctggagccc
atcaccttgctgcagcagaccacctcgggcctggcccatttgcactccctcagcattgtt
cacagagacctgaagccccacaacattctcctgtccatgcccaacgcccatggcaggatc
aaggccatgatctctgacttcggcctctgcaagaagctggctgtgggcaggcacagtttc
agccgccgctcaggagtgcctggcacagaaggctggatcgctccggagatgctgagcgag
gactgtaaggacaatcccacctacacagtggacatcttctctgcgggctgtgtcttttac
tatgtgatatctgagggcagccacccttttggcaagtccctgcagcggcaggccaacatc
ctcctgggcgcctacagcctcgactgcttacacccggagaagcacgaagacgtcattgcc
cgggaattaatagagaagatgatcgcaatggatcctcagaaacgcccctctgcgaagcat
gtgctgaagcacccgttcttctggagcctggaaaagcagctccagttcttccaggacgtg
agtgaccgaatagaaaaggaatccctggacggcccgatagtgaagcagctggagcgaggc
gggagagccgtggtaaagacggactggagagagaacatcaccgtccccctgcagacagat
ctgcgtaaattcagaacctataaaggtggctctgtccgcgaccttctccgagccatgaga
aacaagaagcaccactaccgggagctccccgcggaggtgcgggagacgctgggctctctc
cccgacgactttgtgcgctacttcacgtcccgcttcccccacctcctcccccacacctac
cgggccatggagccctgcagccacgagaggctcttccagccttactactgccacgagccc
ccagagctccggccccccgtgactccagacgccctttga
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