KEGG   Panthera uncia (snow leopard): 125927560
Entry
125927560         CDS       T08832                                 
Name
(RefSeq) nuclear receptor corepressor 1 isoform X1
  KO
K04650  nuclear receptor co-repressor 1
Organism
puc  Panthera uncia (snow leopard)
Pathway
puc01522  Endocrine resistance
puc04350  TGF-beta signaling pathway
puc04919  Thyroid hormone signaling pathway
puc05202  Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:puc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    125927560
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    125927560
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    125927560
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    125927560
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:puc01009]
    125927560
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:puc03036]
    125927560
Protein phosphatases and associated proteins [BR:puc01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     125927560
Chromosome and associated proteins [BR:puc03036]
 Eukaryotic type
  Histone modification proteins
   HDAC complexes
    SMART complex
     125927560
SSDB
Motif
Pfam: GPS2_interact Myb_DNA-binding Myb_DNA-bind_6
Other DBs
NCBI-GeneID: 125927560
NCBI-ProteinID: XP_049493989
LinkDB
Position
E1:complement(49336304..49495753)
AA seq 2517 aa
MSSSGYPPNQGAFSTEQSRYPPHSVQYTFPSTRHQQEFAVPDYRSSHLEVSQASQLLQQQ
QQQQLRRRPSLLSEFHPGSDRPQERRTGYEQFHPGPSPVDHDSLESKRPRLEQVSDSHFQ
RVSAAVLPLVHTLPEGLRSSADAKKDPAFGGKHEAPSSPISGQPCGDDQNASPSKLSKEE
LIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQIIY
DENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTGVPARRMMKNQVMRKKLIL
FFKRRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRK
QREQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAE
QRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSV
PDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQQIARPSQEEKVEEKEEDKAEKTEKKEE
EKKDEEEKDDKEDSKENTKEKDKTEGATEETEEREQATPRGRKTANSQGRRKGRITRSMT
NEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAI
AKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQE
DEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAVKPGEDSTENASSRGNTEPVAELG
STSEPAPSASPSSAVPSTKPVENESAETQANDSITVEAAEPMDVDRQEPSAEVTSVLDLP
ATTRTDSVDVDMRVPENNPSKVEGDTKERDLERAGEKTEPGDEDLVGAQQIGAQRPEPQS
DNDSSATCSADEDVDGEPERQRMFPMDSKPSLLNPPGSILVSSPIKPNPLDLPQLQHRAA
VIPPMVSCTPCNIPIGTPVSGYALYQRHIKAMHESALLEEQRQRQEQIDLECRSSTSPCG
ASKSPSREWEGKSVAYMPYAEVTRALEQEAQMHSTAARSASPCRLSPREVSKAAPQPMSA
ARYSVPPVLQPAPHQVITNLPEAVRLPTTRPTRPPPPLIPSSKTTVASEKPSFILGGSIS
QGTPGTYLTSHNQTSYTQETAKPSVGSISLGLPRQQESAKSATVPYIKQEEFSPRSQNSQ
PEGLLVRAQHEGVVRGTPGAIQEGSITRGTPTSKISLEGIPSLRGSITQGTPALSQAGIP
AEALVKGSISRMPIEENSPEKGREEAASKGHVIYEGKSGHILSYDNIKNAREGTRSPRTA
HEISLKRSYESVEGNIKQGLSMRESPVSAPLEGLICRALPRGSPHSDLKERTVLSGSIMQ
GTPRATTESFEDGLKYPKQIKRESPPIRAFEGAITKGKPYDGITTIKEMGRSIHEIPRQD
ILTQESRKTPEVVQSTRPIIEGSISQGTPIKFDSNSGQSAIKHNVKSLITGPNKLPRGMP
PLEIVPENIKVVERGKYEDVKAGEPVRSRHTSVVSSGPSVLRSTLHEAPKAQLSPGIYDD
SSARRTPVSYQSTMSRGSPMMNRTSDVTISSGKSTNHERKSTLTPTQRESIPAKSPVPGV
DPVVSHSPFDPHHRGGTTGEVYRSHLPTHLDPAMPFHRALDPAAAAYLFQRQLSPTPAYP
SQYQLYAMENTRQTILNDYITSQQMQVNLRPDVARGLSPREQQLGLPYPATRGIIDLTNM
PPAILVPHPGGTSTPPMDRITYIPGTQITFPPRPYNSASMSPGHSTHLAAAASAERERER
EKERERIAAASSDLYLRSGSEQPGRPGSHGYVRSPSPSVRAQEPMLQQRPSVFQGTNGTS
VITPLDPSAQLRIMPLPAGGPSISQGLPASRYSTAADALAALVDAAASAPQMEVSKTKES
KHEASRLEETLRSRSAAVSEQQQLEQKSLEAEKRSVQCLYTSAAFPSGKPQPHSSVVYSE
AGKDKGPPPKSRYEEELRTRGKTTITAANFIDVIITRQIASDKDARERGSQSSDSSSSLS
SHRYEAPGDAIEVISPASSPALPQEKLQAYQPEVVKANQAESEASRPYEGPLHHYRPQQE
SLSPQQQLPPSSQADGVGQVPRTHRLITLADHICQIITQDFARNQVSSQPPQQPPTSTFQ
NSPSALVSTPVRTKTSNRYSPESQSQSVHHQRPGPRVSPENLVDKSRGRPGKSPERSHVS
SESYEPISPPQVPVVHEKQDSVLLLSQRGAEPAEQRNDSRSPGSISYLPSFFTKLENTSP
MVKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVTTSGSVSSRGHSFADPASNLGL
EDIIRKALMGSFDDKVEEHGVVMSQPVGVVPGGASTSVVPSGETRREEGDPSPHSGGVCK
PKLISKSNSRKSKSPIPGQGFLGTERPSSVSSVHSEGDYHRQTPGWAWEDRPSSTGSTQF
PYNPLTMRMLSSTPPTPIACAPSSVNQAAPHQQSRIWEREPAPLLSAQYETLSDSDD
NT seq 7554 nt   +upstreamnt  +downstreamnt
atgtcaagttcaggttatcctcccaaccaaggagcattcagcacagaacaaagtcgttat
cctcctcactctgttcagtacacgtttcccagcacgcgtcaccagcaggaatttgcagtc
cctgattatcgttcttctcatcttgaagtcagccaggcgtcacagctcttgcagcagcag
cagcaacagcagcttcgcagacgaccttccttgctctcagaatttcacccaggttctgac
aggcctcaagaaaggagaactggatatgagcagtttcacccagggccatccccagtggat
catgattcactggaatccaagcggccacgtctggaacaggtttctgattcccatttccag
cgtgtcagtgctgcggtcttacctttagtgcacacgctgccagaagggttgaggtcttct
gcagacgctaagaaggatccagcatttggaggcaaacatgaagccccatcctctccaatc
tctgggcaaccttgtggagatgatcagaatgcttcaccttcaaaactttcaaaggaagag
ttaatacagagtatggatcgtgtagacagagaaattgcaaaagtagaacagcagatcctc
aaactgaagaagaaacaacaacagctcgaagaagaagccgctaagcctcctgagcctgag
aagcctgtgtcccctcctcccgtggagcagaaacaccgcagtattgtccaaattatttat
gatgagaatcggaaaaaagcagaagaggctcataaaatatttgaaggtcttggcccaaaa
gtggaactgccactctataaccagccatcagataccaaggtgtatcatgagaacatcaag
actggagtacctgcaaggcgcatgatgaaaaaccaggtgatgaggaaaaaactcatttta
ttttttaaaagaagaaatcatgcaagaaaacaaagggaacaaaaaatctgccaacgttat
gatcagctcatggaggcatgggagaaaaaagtggacagaatagaaaataatccccggaga
aaagctaaagaaagcaaaacaagggagtactatgaaaagcagtttccagaaattcgaaaa
caaagagaacaacaagaaaggtttcagcgagttgggcagaggggagctggtctttcagcc
acgattgctaggagcgagcatgagatttctgaaattattgatgggctctctgagcaggag
aataatgagaaacaaatgcggcaactctctgtgatcccacctatgatgtttgatgcagaa
cagagacgagtcaagttcatcaacatgaatggactcatggaagatcctatgaaagtttat
aaagacaggcagtttatgaatgtttggactgaccacgagaaggagatctttaaggacaag
tttatccagcatccaaaaaactttggactaattgcatcctacttggaaagaaagagtgtt
cctgattgtgttttatattactacttaaccaagaaaaatgagaattataaagccctagta
agaaggaattacggaaaacgcagaggaagaaaccagcagcaaattgcccgaccctcgcaa
gaagaaaaagtagaagaaaaagaagaagataaagcagaaaaaacagaaaaaaaagaagag
gaaaagaaagacgaagaagagaaagatgacaaggaggactctaaagaaaataccaaggaa
aaggacaagacagaaggtgcaaccgaagaaacggaggagagagagcaggccacaccccgg
gggcgaaagaccgccaacagtcagggccgcagaaagggccggatcaccaggtccatgacc
aacgaagccgcggctgccagtgctgcggccgctgccgccactgaggagcccccaccgcct
ctgccaccgccaccagaacccatttccacagaacctgtagaaacctctcgatggacagaa
gaagaaatggaagttgcgaagaaaggtcttgtagaacatggtcgtaactgggcagcaatt
gccaaaatggtgggaactaaaagtgaagcgcagtgtaaaaacttctattttaactacaaa
aggcgacacaatctggacaaccttctgcagcagcataagcagaaaacttcacgaaagcct
cgtgaagagcgagatgtgtctcaatgtgaaagtgtagcttccactgtttctgctcaggag
gatgaagatattgaagcttctaatgaagaagaaaatccagaagacagtgaaggtgctgaa
aatagttctgatacagaaagtgctccttctccttcaccagttgaagctgtcaagcccggc
gaagatagcactgaaaatgcgtcttctcgagggaacacggaacctgtggccgagctcggg
tccacctccgaacctgcgcccagtgcgtctccctcctcggcagtgccaagtacgaagccc
gtcgaaaatgaaagcgcggagacccaggcgaatgacagcatcaccgtagaggcagcagag
ccgatggacgttgaccggcaggagcccagtgctgaagtgacttctgttcttgacctcccc
gcgactaccagaacggactctgtagatgttgacatgagggtgcccgaaaacaatccgtcg
aaagtcgaaggcgataccaaagagagagacctggagagagccggcgagaagacagagcct
ggcgatgaagacttggtgggggcccagcagataggggcccagaggcccgagccccagtcg
gacaatgattccagtgctacctgcagtgctgatgaagatgtagatggagagcccgagagg
cagagaatgtttcccatggactcaaagccttcattgttaaaccctcctggatctatactg
gtctcatccccaataaaaccaaatccactggacctgccacagcttcaacatagagctgct
gttatcccaccgatggtttcctgtaccccatgtaatataccaattggaaccccagtgagc
ggctatgccctgtaccagcgtcacattaaagccatgcatgagtctgcgctcctggaagaa
cagcgacagaggcaagaacagatagatttggaatgtagaagttccacaagcccgtgtggc
gcctccaagagtccaagcagagagtgggaaggaaaatcagtcgcctatatgccctatgct
gaggtcacacgtgccctagaacaggaagcacagatgcacagtaccgcagcaaggtcagca
tcaccgtgtaggctctctccgagagaagtcagtaaagccgctccacagcctatgagtgca
gcccgctatagtgtcccgccagtcctgcagcctgctccacatcaagtgataaccaatctc
cccgaggcggttcggcttccgacaactcgacccacgaggccacctcctccacttattcca
tcatctaaaaccacagtggcttccgaaaaaccctctttcatcctgggaggctccatctcg
cagggaacacctggcacttatttgacttctcataatcagacttcctacactcaagaaaca
gctaagccctcagtgggttctatctctcttggattgccacggcaacaggaatctgccaaa
tcagctactgtgccctacatcaagcaggaggaattttctccccgaagccagaactcccag
cccgagggtttattggtcagggcacaacacgaaggagtggtcagaggtactccaggagcc
attcaagaaggaagtataactcgggggactccaaccagcaaaatttccctggaaggcatc
ccatccctgcggggctccatcactcagggtaccccagctctgtcacaggctggcataccg
gctgaggctctggtgaagggatccatttctagaatgcccatcgaagagaacagtcctgag
aagggcagagaggaagctgcatcaaaaggtcatgttatttatgaaggcaaaagtggacac
atcttatcatacgacaatattaagaatgcccgagaagggacaaggagtccaagaacagct
catgaaatcagtttaaaaagaagctatgaatcagtggaaggaaatataaagcaagggttg
tcaatgagggagtctcctgtgtcagcaccactagaggggctgatatgccgagcattaccc
agggggagccctcattctgacctcaaagaaaggactgtgctgtctggttccataatgcag
ggcacaccaagagcaaccaccgaaagctttgaagatggtctaaaatatccgaaacagatt
aaaagggagagtcctcccatacgagcatttgaaggcgccattaccaaaggaaaaccatat
gatggtatcaccaccatcaaagaaatggggcgttccattcatgagattccacggcaagat
attttaactcaggaaagccgtaaaactccagaggtggtccagagcacaaggccaatcatt
gagggttccatctcccagggtacaccgataaagtttgacagcaactcaggtcaatctgcc
atcaaacacaacgtcaagtctttaatcacggggcctaacaaactaccccgtggaatgcct
ccactggaaattgtgccagagaacatcaaagtggtagaacgggggaaatacgaggatgtg
aaggcaggcgagccagtgcgttcccgacatacatcggtggtaagctctggcccctcagtt
cttaggtcaacacttcatgaggctcccaaagcacaactgagcccagggatctacgacgac
agcagtgcccggcggacgcctgtgagttatcagagcaccatgtccagaggctcgcctatg
atgaacagaacttcggatgttaccatctcttctggcaagtctaccaatcatgaaagaaaa
tcgacactgacccctacccagagggaaagtataccggcgaagtctccggtgcctggggtg
gacccggtagtaagccacagcccttttgatccccatcacaggggcggcaccacgggagag
gtttatcggagccatcttcccacgcatttggatcccgccatgccgtttcacagggctctg
gatcctgcagctgccgcttacctgtttcagagacagctctcaccaaccccagcttacccg
agtcagtatcagctttacgcaatggagaacacgagacagacaatcctcaatgattacatt
acctcacagcagatgcaggtgaacctgcgcccagatgtggccagaggcctctccccacgg
gagcagcagctgggtctcccgtacccggcaacgaggggaatcattgacctgaccaatatg
cctccagcaattttagtgcctcatccagggggaacaagtactccacccatggacagaatc
acttatattcctggtacacagattacgttcccccccaggccatacaactctgcttctatg
tctccaggacactcaacgcaccttgcggcggccgcgagtgcggagcgggagcgggagcgc
gagaaggagcgggagcggatagccgcggcgtcctcggacctctacctgcggtcgggctcc
gaacagccgggccgacctggcagccacgggtatgtccgctccccgtccccttcggtgaga
gctcaggagcccatgttgcagcagagacccagcgttttccagggaaccaacggaaccagt
gtaatcacaccgttggatccaagcgctcagctgcgaatcatgccgctgcccgccgggggc
ccgtcgataagccagggcctgccggcctcccgctacagcaccgctgcggacgccttggcc
gccctcgtggacgccgcagcctctgccccccagatggaggtttccaaaacgaaagagagt
aagcatgaagcttccaggttagaagaaactttgagaagcaggtcagccgcagttagtgag
cagcagcagctagagcagaaaagcctggaggcggagaagagatctgttcagtgtctgtac
acctcggccgcctttccaagtggcaagccccagcctcactcttcggtagtttactcagag
gctgggaaagataaagggcctcctccaaaatccagatatgaggaagagctaaggacccga
gggaagactaccattaccgcagctaacttcatagacgtgatcatcacccggcaaattgcc
tcggacaaggatgcgagggaacgtggctctcaaagttcagactcttctagtagcttatct
tctcatcggtatgaagcgcctggcgatgctattgaggtgatcagtcctgccagctcgcca
gcgctgccccaggagaagctacaggcctatcagccggaggtggtgaaggcaaaccaagca
gaaagtgaagccagcagaccatacgaaggaccattacatcactaccgaccccagcaggaa
tccctgtctccacagcagcagctgcccccctcttcacaggccgacggggtggggcaagtg
cccaggacccaccgactgatcacactcgctgatcacatctgtcaaatcatcacacaagat
tttgctagaaatcaagtttcctcacagcctccccagcagcctcccacttctacattccaa
aattcaccatctgctttggtgtccacacctgtgaggactaaaacatcaaatcgttacagc
ccagaatcccagtctcagtctgtccaccatcaaagaccaggtccaagggtctctccagaa
aatcttgtggacaaatccaggggaaggcctggaaaatccccagagaggagtcacgtctct
tctgagtcctacgagcccatctccccaccccaggttccagtcgtgcatgagaaacaggac
agtgtactgctcctgtctcagagaggggcggagcctgcagagcagaggaatgattcccgc
tcgccagggagtataagctacttgccttccttcttcaccaagctcgaaaacacgtcaccc
atggttaaatcaaagaagcaggagatttttcgtaagttgaactcctctggtggaggtgac
tctgatatggcagccgctcaaccaggaactgagatctttaatctgccagcagtcactacc
tcaggctcagttagctctagaggtcattctttcgctgatcctgccagtaacctcggtctg
gaagacatcatcaggaaggcgctcatgggaagctttgacgacaaagtcgaggagcacgga
gtcgtcatgtcccaacctgtcggcgtggtgcccggtggcgccagcacctccgttgtgccc
agtggggagacccgcagagaggaaggggacccgtcacctcattcaggaggagtttgcaaa
ccaaagctgatcagcaagtcaaacagcaggaaatctaaatctcccatccctgggcaaggc
ttcttaggaactgaaaggccctcttccgtctcctctgtacattcagaaggggattaccac
aggcagacaccagggtgggcctgggaagacaggccctcctcaacaggctcgactcagttt
ccttacaaccctctgactatgcggatgctcagcagtacgccaccgaccccgatcgcgtgt
gccccgtcctccgtgaaccaagcggctcctcaccagcagagcaggatctgggagcgagag
cctgccccgctgctctctgcacagtacgagacgctgtcggatagcgatgactga

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