Panthera uncia (snow leopard): 125927591
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Entry
125927591 CDS
T08832
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
puc
Panthera uncia (snow leopard)
Pathway
puc05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
puc00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
125927591
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
puc03021
]
125927591
Enzymes [BR:
puc01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
125927591
5.6.2.5 RNA 5'-3' helicase
125927591
Transcription machinery [BR:
puc03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
125927591
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
UvrD-helicase
AAA_30
AAA_22
nSTAND3
ResIII
SLFN-g3_helicase
Helicase_RecD
AAA_16
UvrD_C_2
Motif
Other DBs
NCBI-GeneID:
125927591
NCBI-ProteinID:
XP_049494054
LinkDB
All DBs
Position
D4:complement(87515531..87579829)
Genome browser
AA seq
2669 aa
AA seq
DB search
MSTCCWCTPGGISTADFLKRYASRTHAGEFQTADEDLCYCLECVAEYHKARDDLPFLHEV
LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEAQLFDFTGQDFENKLRVPLLEILKY
PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK
VDRDDYYDLQEVLTCLFKVIELGLLEDPDIYTCSVLEKGKLILLPAHMYDTTNYKNYWLG
ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMERQADDDSVDPFWPALHCFMVILDRL
GSKVWGQRIDPIEAFQTIISNMSYNREIQNIRNSSVRTKSEPESYLDDTVTCSQIVYNYN
PEKTKKDSGWRSAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD
LKDLGVAYIVEVIHHLHSEVKDVLNQTDAVCDKVTEFFLLILVSVIELHRNKKCLHLLWV
SSQQWVEAVVKCAKLPTTAFARSSEKSSGNCSKGAAVISSLSLHSMPSNSVQLACVQLIR
SLLKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQLTTQETHELQTCLKQIIRNIKFKVP
QCSTFVDLTPVCKTPPASYNKEESEQTGKKSKKGLPCPENSSPTFSKGPTKAEAFQMPEN
RLVKASNAGEEDSEHSYIKDLKLEGRLSAETCIKQGSKRLFPERAQDAVKTSKGKQKSVK
ENPTDSRNGPERGCDRGVIIAARSLTDSGTDSLEKASTSTEDFSFKDDVLGKTSKGKTKG
QKAEICAKLSHVIKKQHRKSTLIDDVNLEETLTVSTIDSFFSRKDSGGQKGDGFINHLSL
DPDDVPDDKNGERKSQNSLLLKKKHFKTKELDIFSAHENSCQIQERQADGKDLVSFTEMA
DPCVKKTSPFKDPVTLLESRDKEAGKSTTSQGSSHLREQAPSLSPQSNTLTDSQIDRDLH
KLSLIAQASVIKFPSESTQKSSSQLQRKVKDKRCFTANPNNAGEACRGQVIIISDSDDDD
GDEGILGFEKHIKRDKIGIKKEYPEEHTSVASTNVEQKLIKEEEAKSLLEFEESDSQFFE
FESPHEVFSVWQDQEPDDKNSVQEDENKSRLTRLNDVTNDWGYDTDYVSEEVIKKVAEGI
EKHTEPQSGSSVGEFCATEVKKRKRKRYEKPVAEDPLRPSPSERNEDQSDNERGLTGSDL
KSIELRSSSRSNLQRDTTDSLKKSSPKLRTYSKPVRRVPHSKTKKTHSDTKKGQNKSSNY
ISCRTTPAIVPPKILRQCPEPTSTVEKLGLKKAPRRAFDLSQRSLGYLVQLRDHGKTVGV
VDTRKKAKLISPQTLSLKNNKKLLTSQDLQSRRQAKHKSKQKRRGSLGSESRTPTRAGLR
SAQNPDPPVPESDSSDYRANGGAEVGATNTGKPSIKRASSEPEPVKTIRVSQVADDPCLS
NQCTSVVLNGREATHEAIVSTSADPLGGGDLTEHRLELTALKEGEPRCNSDSEDENIFLT
QRDPADMDLCSQMENGNEKLIEVVHGKETALMEEESWSSTKCKYKDCVEAAQKQGEYCSK
HCEAKAVDEDVFRKPGLPPSASKRPSTAKVFSSSSTSRIANLSKSLESSSIPPPALKQKS
NGVPSVLKVPQPASVLSPKPMGEVKSLSDVLRPQTLNNSNRQGYKLTFGESRSFSASSAV
NVLLSSQSISDTFVKEVLKWKYEMFVNFDQCGPPTSLCQSISRPVPVRFQDCGDYFSVFF
PLMILNTFETVAQEWISSPNKEKFYQLHVRKFPADYKKYWEFVVHLEECELTKQLHPKEN
DLVFLVLEKQNGEKKNTERSRMPDLHEYHCGYVHKFRRTSVMRNGKSECSLSIQTQDNLP
LSLNELVKCTVISSLVTTQRKLKAMSLLSGRNQLARAVLNPNPMDFCTKDLLTTTSERII
AYLKDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRLLTENQRKG
RSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGDINLVRLGP
EKSINNEVLRFSLDSQVNHRMKKDLPSHVQEMHRRKEFLDHQLDELSRQRALCRGGKETQ
RQELDEKIAKVSKERQELASKIKEVQGRPQKTQSIIILESHVICCTLSTSGGLLLESAFR
GQGGVPFSCVIVDEAGQSCEVETLTPLIHRCNKLILVGDPKQLPPTVISMKAQEYGYDQS
MMARFCKLLEDSVEHNVIGRLPVLQLTVQYRMHPDICLFPSNYVYNRSLKTNRLTETNRC
SSDWPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKDKRRDVTFRNIGIITHY
KAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANAMQGSIGFLASLQRL
NVTITRAKYSLFILGHLRTLMENQHWNHLIQDAQKRGAIVKTCDKNYRHDAAKILKLKPV
LQRSLTHPPTVAPEVARPQGGLPSSKPDGEFAKTSFPSSLYHVPSGCKESTGTVTTKDPE
RPPIQDRLRDPRLLRRLGIDPEAKGTCPRDPQPLSPQHPGATPPSGEPGFPLSHQDLGGA
QLSTARGTTLSNQNPPVQWEPPAAGTDVSASKRACDWEGGLSRRRETRAFSEGDRETQSP
ESRHPKRRSGWDNRRLEEEASGSKKRKFL
NT seq
8010 nt
NT seq
+upstream
nt +downstream
nt
atgagcacgtgttgttggtgtacgcccggtggtatttccaccgctgacttcctcaagcgc
tatgcgtccaggacccacgccggggaatttcagacagccgacgaagacctctgctactgc
ctggagtgtgtggccgagtaccacaaagcacgcgacgacctgcccttcctgcatgaggtt
ttgtgggaattagaaaccttacgtctcataaatcattttgaaaaatccatgaaggcagaa
attggggacgatgatgaattgtacatagtagacaacaatggagaggcacagctttttgac
ttcactggccaagactttgaaaataagcttcgggttcctcttcttgaaatcctgaagtat
ccgtatctgcttttacacgagcgtgttaacgaattatgtgttgaagcactttgtcggatg
gaacaagctaattgctcctttcaggtttttgacaaacatccaggcatttatttgtttctg
gtccatcccaatgaaatggttcggcgttgggctatcctgaccgcaaggaacttgggaaaa
gtggacagagatgactattatgatctgcaggaggttttgacttgtctttttaaagtcatt
gagttggggcttctggaagatccagacatctacacttgttctgtcctcgagaagggtaaa
ctgattcttctgcctgcgcacatgtacgataccaccaactacaagaactattggctaggt
atttgcatgttgctgaccattcttgaggagcaggctatggactccctgttgctgggctcg
gacaaacagaatgatttcatgcaatcaatccttcacaccatggagaggcaagcagatgat
gatagcgtggatcctttctggccagcattacactgtttcatggtgattctggatcgcctc
ggatcaaaggtctggggtcaacgcatcgatcctattgaggcgtttcagaccattatcagt
aacatgagctacaatagagagatccaaaatatacggaacagctctgtaaggaccaagtca
gaaccggagtcgtatttggatgatacagtgacttgtagccagatcgtgtacaattacaac
cctgaaaagaccaaaaaggattccgggtggagatcagccatttgcccagattactgtcct
aacatgtacgaagagatggaaacgttagccagtgtgcttcagtcagatatcggtcaagac
atgcgtgttcacaatagcacgtttctgtggttcatcccctttgttcagtccctcatggat
cttaaggatttgggtgtggcttacatagtagaggtgattcaccatctgcactctgaagtc
aaagatgtcctcaaccaaacagatgctgtgtgtgacaaagttactgagtttttccttctg
attttggtgtccgtgattgaactgcacagaaataaaaaatgtttgcacttgctgtgggtt
agttcccagcagtgggtggaggctgttgtaaaatgcgccaagcttcccaccaccgcgttt
gcacggagttctgagaagtcatctggaaattgctccaaaggagcagcagtgatctcgtct
ctgtcactgcattcgatgccatctaattctgtccagctggcttgtgtgcagctgatcaga
agtctccttaaagaagggtatcagcttgggcagcagactctgtgcaagcgattctgggac
aagctcaacttgtttctgcgtgggaatttatctctgggttggcagttgactactcaggaa
acccatgagttacaaacttgtttaaagcaaattattagaaacataaaattcaaagtacct
cagtgtagcacttttgtggatctgactcccgtatgtaaaacccctcctgcgtcttacaat
aaagaagaaagtgaacagacagggaagaaatctaaaaaaggcctgccctgtccggaaaac
tccagcccaacattttctaaaggaccaacgaaagctgaagcatttcaaatgccagagaat
agattggtcaaagcaagtaacgctggcgaagaggatagtgagcacagttacataaaagat
ttgaaactagaaggccgtctctcagcagagacgtgcataaagcagggtagcaaaaggctt
ttcccggaaagagctcaagatgcagttaaaacaagtaaagggaagcagaagtctgtgaag
gagaatcctacggattccagaaatggtccggaaaggggatgtgacagaggggtgataata
gccgcacgttcgttgactgattctggcaccgactccctggagaaggcgtccacatcaact
gaggatttctctttcaaggatgatgttcttggcaaaacctcaaaaggaaaaactaaggga
cagaaagctgaaatctgtgctaagttatcacatgtaataaagaagcaacacaggaaaagt
actttgatcgatgacgtcaatttagaggaaacactgactgtgtctaccattgacagtttc
ttttcaaggaaagattcaggaggtcagaaaggggatggcttcataaaccatctctcttta
gaccctgatgacgttcccgatgataaaaacggggagcgaaaatctcaaaacagtttattg
ctgaagaagaaacacttcaagaccaaagagttagatattttctctgcccatgaaaatagc
tgtcaaatacaggaacgccaagcggacggtaaagatttggtctcgtttacggaaatggcc
gatccttgtgtgaagaaaacctctcccttcaaagaccccgtgactcttcttgaatcgaga
gataaggaagctggcaagagtaccaccagtcaggggtcttctcacttgagggaacaggct
cctagcctcagtccacagtccaacaccttgacagattcccagatagaccgagacctccac
aaattatctttgatagcccaagccagtgttattaagtttccgtcggagtcaactcaaaag
agctcatcccagctacaaagaaaagtaaaagataaaaggtgtttcacagctaacccgaat
aatgctggagaagcctgccggggccaggtgattatcatttcagattctgatgatgatgat
ggtgacgaagggattctgggttttgagaaacacattaaacgagataaaataggcatcaag
aaagaatatccagaggagcatacttcagtagctagtacaaatgtggaacagaagctaata
aaggaagaagaggcaaagtccctattggagtttgaggaatcggattctcagttttttgag
tttgaaagtccacatgaggtgttttcagtttggcaagatcaggaaccagacgacaagaac
tcagttcaagaggatgaaaacaagtcacgtctgactcgcctaaacgatgtcacgaatgat
tggggttatgatacagattatgtatctgaagaggttattaagaaagtagcagagggcatt
gaaaaacacacagaaccacagagtggtagttctgtcggggaattttgtgcaactgaagtg
aaaaaacgtaagagaaaacgatatgaaaaacctgtagctgaagatcctctgaggccttca
ccttctgagagaaatgaggaccagtctgataatgagagaggtctgactggaagtgatctt
aaaagtatagagctgaggtcaagttccaggtcgaatcttcaaagagacactacagattca
ctaaagaagtcttctccaaagcttcgtacttactccaaacccgttaggagagtcccgcat
tctaaaactaagaaaacacattcagataccaaaaaagggcagaataaaagttcgaattac
ataagctgtaggacgactcctgctatagtcccaccaaagatacttcgccagtgccctgaa
ccaacttcaactgttgaaaaacttggtctgaaaaaggctcctcgtagggcattcgattta
tctcagcgatctctagggtatttagttcagttacgggaccatggcaaaaccgtgggagtg
gttgataccagaaaaaaggctaaattaatttctcctcagactctctctctcaaaaataat
aagaaactgttgacaagtcaagatcttcagtcgcgaaggcaggcgaaacacaaatcaaag
cagaagaggcgaggatctctgggttctgaaagtaggactcctacaagagcagggctgcgt
tcagcccagaatcctgaccctcccgtcccagaatccgatagctcagattatcgtgctaac
ggaggcgccgaggtgggtgctaccaatactggaaagccatcgataaaacgcgcgtcttcg
gaaccagaacccgtgaaaacgatacgtgtttctcaggtggctgatgatccttgcctttcg
aaccagtgcacttctgttgtgttaaatggaagagaagcaacacatgaagccattgtctct
acgtcagctgaccctttaggtggaggcgacctaacagaacatcgtttagagttgaccgct
ctgaaagagggagagcccagatgcaacagtgactcggaagatgagaatatatttctaacc
cagcgcgatcccgcagatatggatttatgttcacaaatggaaaatggtaacgagaaactc
atcgaagtagttcatggaaaagagacagctctgatggaagaagaatcctggagcagcaca
aaatgtaagtacaaggattgtgtcgaagccgcgcaaaagcagggtgaatactgctccaaa
cactgcgaagctaaagcggtggatgaagatgtgtttcgtaaaccgggcctgcccccctct
gcgtccaagagaccctccactgccaaggtctttagctcaagtagtacttcacgaatcgcc
aatctttcgaagtctttggaaagttcctccataccgccaccggctctcaaacagaagtca
aacggggtaccatctgttttgaaagtcccacagccagcctctgtgttgtctccaaagcca
atgggtgaggtgaagagtttgtctgatgttctccgtcctcagaccctgaataattccaac
aggcaaggttacaagcttacgtttggcgaaagcagatctttttcggcttcctctgcggtg
aatgttctcttgtcctcacagtctatctcggacacctttgttaaagaggtcttaaagtgg
aagtacgaaatgtttgtgaactttgatcagtgtgggccccccaccagcctttgtcagtcc
atctcaagaccggtgcctgtcagatttcaagattgtggagattatttcagtgtttttttc
cctttgatgatactgaatacttttgaaacggtggcacaggagtggatcagctctccaaac
aaagagaagttctatcagttgcatgtacggaaatttcctgctgattataaaaagtactgg
gagtttgtggttcatcttgaggaatgtgaactaactaaacagctgcatccaaaggaaaat
gatttggtgtttttggttcttgaaaaacaaaatggagagaagaagaacacagagagaagt
cgcatgccggatctccacgaatatcactgcggttatgttcataaatttcgccgcacctca
gtcatgcgtaatgggaaatctgagtgttccctttccatccagactcaagataatttgcca
ctcagtttaaatgaactcgtgaaatgcactgtaatcagttctctggtaactacacagagg
aagttgaaagccatgtctttgttgagtggacggaaccaactagccagagctgttctgaac
ccaaaccccatggacttctgtacgaaagatttactgactacgacgtctgagagaatcatc
gcctacttgaaagatttcaacgaagaccaaaagaaagcgatagaaactgcatacgccatg
gtcaaacactccccatcggttgccaagatctgtttgattcatggaccacctggaacagga
aagtcaaaaacgatcgttggccttctgtaccgcctgctgacagagaaccagaggaagggg
cgttcagatgaaaactccaatgccaaaatcaaacaaaaccgtgtccttgtgtgtgcacct
tccaacgcggctgttgatgaacttatgaaaaaaatcatcctcgaatttaaagagaagtgt
aaagacaagaagaatcctttgggaaactgtggagatataaatttagtacgtctgggtcca
gaaaagtctattaataatgaggtcctaagatttagtttggacagccaagttaaccacaga
atgaaaaaagacttaccttctcatgttcaggagatgcatagaagaaaggaatttctggat
catcagctagatgaactttcccgccagcgtgctttatgccgaggtggaaaggaaacacag
aggcaagaattagatgaaaaaatcgcaaaggtttcaaaagagaggcaggaactagcttct
aaaattaaagaggttcaaggacgcccacaaaaaacacagagcatcatcatcttagagtcc
cacgtcatctgctgcacactgagcacgagtggcggtttactgctcgagtctgcttttcgt
gggcaagggggtgtccccttcagttgtgtcatcgtcgatgaggctgggcagtcttgtgaa
gtggagactcttaccccgctcatccatcgttgtaacaagctgatcctcgtcggagaccca
aaacagctccctcccacggtcatttccatgaaagcacaggagtatggctatgaccagtcg
atgatggctcgcttctgcaagctgctggaagacagcgtagagcacaatgtgatcggcagg
ctgcctgttttacagcttactgttcagtacaggatgcacccagacatatgtctcttcccc
tctaattatgtttataacagaagcttgaaaacaaatagactgactgaaaccaatcggtgt
tcatcagactggccatttcaaccttacctcgtgtttgatgtcggagacggttcagaaaga
cgggataatgactcatatataaatgttcaagaaataaaactggtaatggaaataattaaa
cttattaaagacaaaagaagggatgttactttccggaacattggcataataacccattac
aaggctcagaagacgatgattcagaaggatttggacaaagagtttgatagaaaagggccg
gcagaagtagatactgtggacgcgttccagggccgccagaaagattgtgttatcgtcacg
tgtgtcagagcaaatgccatgcaaggctccattggatttctggcaagtttgcaaagattg
aatgtcaccattacacgagccaagtacagcctcttcatcctcggacatttaaggaccttg
atggaaaatcagcactggaatcacctgattcaggatgcacagaagcggggtgccattgtc
aagacgtgcgacaaaaactacaggcacgacgcagccaagattctgaaactcaagcccgtc
ctgcagagaagtctgactcacccgcccaccgtggccccggaggtggccaggccccagggt
ggcttgcccagcagcaagccagacggtgaatttgccaagacgtctttcccttcctccctg
tatcacgtgccttctggctgtaaggaatccactggtactgttaccaccaaggaccctgaa
agacctcctattcaggaccggcttcgggacccacgactgcttaggaggctgggcatagac
cccgaagccaaagggacatgcccgagggatccgcagcccctgagcccccagcatcctggg
gccacacctccctcgggggagccaggcttccctctgagtcaccaggacctgggtggtgcc
cagctgtccaccgccagagggaccacgctgagcaaccagaaccctcccgtgcagtgggag
cctccagctgccggtacggatgtctccgctagtaaaagagcatgtgactgggaaggaggg
ctcagccgcaggagagagaccagggctttcagcgaaggggaccgggagacgcagagcccg
gagagccgtcacccgaagaggcgctctggctgggacaacaggagactggaggaggaagcc
agtggttccaagaaaagaaagtttttatag
DBGET
integrated database retrieval system
