| Entry |
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| Name |
(RefSeq) multidrug resistance-associated protein 1 isoform X1
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| KO |
| K05665 | ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3] |
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| Organism |
puc Panthera uncia (snow leopard)
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| Pathway |
| puc04977 | Vitamin digestion and absorption |
| puc04981 | Folate transport and metabolism |
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| Brite |
KEGG Orthology (KO) [BR:puc00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
125927918
09132 Signal transduction
04071 Sphingolipid signaling pathway
125927918
09150 Organismal Systems
09154 Digestive system
04977 Vitamin digestion and absorption
125927918
04981 Folate transport and metabolism
125927918
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
125927918
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
125927918
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:puc02000]
125927918
Enzymes [BR:puc01000]
7. Translocases
7.6 Catalysing the translocation of other compounds
7.6.2 Linked to the hydrolysis of a nucleoside triphosphate
7.6.2.3 ABC-type glutathione-S-conjugate transporter
125927918
Transporters [BR:puc02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
125927918
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
E3:7440345..7540269
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| AA seq |
1533 aa
MQTSVALWCSLLTVTLCSCPQEWSVTWNTSNPDFTKCFQNTVLVWVPCSYLWVCFPFYFL
YLCHHDRGYIQMTHLNKTKTALGFLLWIVCWADLFYSFWERSWGKFLAPVFLVSPTLLGI
TMLLATFLIQLERRKGVQSSGIMLTFWLVALLCALAILRSKIMTALKEGAEIDVFRDVTF
YIYFSLVLIQLVLSSFSDRSPLFSETIHDPNPCPESSASFLSRVTFWWITGLMVRGYRQP
LESADLWSLNKEDTSEQVVPVLVKNWKKECAKSRRQQAKIAYSSKDPAKPKGSSQVDVNE
EAEVLIVKSPQKGREPSLFKVLYKTFGPYFLMSFLFKALHDLMMFAGPEILKLLINFVND
TKAPDWQGYFYTALLFVSACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSAR
RSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVVLALYLLWLNLGPSVLAGVAVMIF
MVPVNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEE
LKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVYVTVDKNNILDAQKAFVSLALFNILRFP
LNILPMVISSIVQASVSLKRLRIFLSHEELEADSIERKPGKDGGGTNSITVKNATFTWAR
SDPPTLNGITFSVPEGSLVAVVGQVGCGKSSLLSALLAEMDKVEGHVSVKGSVAYVPQQA
WIQNDSLRENILFGRPLQEWYYKAVIEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQR
VSLARAVYCDSDIYLFDDPLSAVDAHVGKHIFENVVGPKGMLKNKTRLLVTHSISYLPQV
DVIIVMTGGKISEMGSYQELLARDGAFAEFLRTYASTEQEQSEQDDGISSPGKETKQMEN
GMLVTDVAGKQLQRQLSNSSSYSGDVSRHHTSTAEPQKAGAQDEDAWKLVEADKAQTGQV
KLSVYWDYMKAIGLFIAFLSIFLFLCNHVAALASNYWLSLWTDDPIVNGTQEHTKVRLSV
YGALGISQGISVFGYSMALSIGGIFASRRLHLNLLQNVLRSPMSFFERTPSGNLVNRFSK
ELDTVDSMIPQVIKMFMGSLFNVIGACAIILLATPIAAIIIPPLGLIYFFVQRFYVASSR
QLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRW
LAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSELETNI
VAVERLKEYSETEKEAPWQIPETAPPSTWPQVGRVEFRDYGLRYRENLDLVLKHINVTID
GGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDDINIAKIGLHDLRFRITIIPQDPV
LFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSALPDKLNHECAEGGENLSVGQRQLV
CLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFDDCTVLTIAHRLNTIMDYTRVI
VLDKGEIRECGHPLDLLQERGLFYSMAKDAGLV |
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| NT seq |
4602 nt +upstreamnt +downstreamnt
atgcagacgtctgtggctctttggtgcagcctcttgaccgtgaccctgtgttcctgtccg
caggagtggagtgtgacatggaacaccagcaaccccgacttcaccaagtgctttcagaac
accgtcctcgtgtgggtgccttgttcttatctctgggtctgcttccctttctacttcctc
tatctctgccaccatgaccgggggtacattcagatgacacatctcaacaaaaccaaaact
gccttgggatttttgctgtggatcgtctgctgggcagacctcttctactctttctgggaa
agaagttggggcaaattcctggccccagtgtttctggtcagcccaaccctcttgggcatc
actatgctgcttgctacctttttaattcagctcgagagaaggaagggagtccagtcctcg
gggatcatgctcactttctggcttgtagccctactgtgcgcccttgccatcttgagatcc
aaaatcatgactgccttaaaagagggtgctgaaattgatgtgtttcgcgatgtcactttc
tacatttacttttccctcgtgctgattcagctcgtgttgtcctccttctcggaccgatcg
cccctgttctctgaaaccatccacgaccccaacccctgcccggaatccagtgcctccttc
ctgtccagggtcaccttctggtggatcacagggttgatggtccggggctaccgccagccc
ctggagagcgctgacctctggtccctgaataaggaggacacctcagagcaagtcgtgccc
gttttggttaagaactggaaaaaggagtgtgccaagtccagaaggcagcaggcaaagatc
gcgtactcctccaaggatcccgccaagccgaaagggagctcccaggtggacgtgaatgag
gaggccgaggttttgattgtcaagtcccctcagaagggccgggagccgtctctgttcaag
gtgttatacaagaccttcgggccctacttcctcatgagcttcttattcaaggccctccat
gacttgatgatgtttgccggcccggagatcttaaaattgctcatcaacttcgtgaacgat
acgaaggccccggactggcagggctacttctacacggcgctgctgttcgtcagcgcctgc
ctccagacccttgtgctgcaccagtatttccacatctgcttcgtcagcggcatgaggatc
aagacggccgtcatcggggccgtctaccggaaggccttggtgatcaccaattcagccaga
aggtcttccacggtcggggagatcgtcaacctcatgtccgtggatgcccagaggttcatg
gacctggccacgtacatcaacatgatctggtcagcccctctgcaggtcgtccttgccctc
tacctcctgtggctgaatctgggcccctccgtcctggctggagtggctgtgatgatcttc
atggttcccgtcaacgccgtgatggccatgaaaaccaagacctaccaggtggcccacatg
aagagcaaagacaatcggattaagctgatgaatgagattctcaacgggatcaaagtgcta
aagctgtacgcgtgggaactggccttcaaagacaaggtgctggccatcaggcaggaggag
ctgaaggtgctgaagaaatcggcctacctggcagccgtggggaccttcacctgggtctgc
acacctttcctggtggccctgtctacatttgccgtctacgtgactgtcgacaagaacaac
atcctggatgcccagaaagctttcgtgtccttggccttgttcaacatcctccggtttccc
ctgaatattctccccatggtcatcagcagcatcgtgcaggcgagtgtctccctcaaacgc
ctcaggatctttctgtctcacgaggagctggaggccgacagcatcgagcggaagcctggg
aaagacggtgggggcacaaacagcatcaccgtgaagaatgccacgttcacatgggccagg
agtgaccctccaacgctgaatggcattaccttctccgttccggaaggttccttggtggcc
gtggtgggccaggtgggctgtggaaagtcgtctctgctctcagcactcctggccgagatg
gacaaggtggagggccacgtgtctgtcaagggctcagtggcctacgtcccccagcaggcc
tggattcagaatgattctctccgagaaaatatccttttcggacgcccgctccaggaatgg
tattacaaggcagtgatcgaagcctgtgccctcctcccagatctggagatcctgcccagc
ggggaccggacggagattggtgagaagggcgtgaacctctctgggggccagaagcagcgt
gtgagcctggcccgggccgtgtactgtgactctgacatctacctcttcgatgaccccttg
tcggcggtggatgcccatgtgggaaaacacatatttgaaaatgtggttggccccaagggg
atgctgaagaacaagacacggctcctggtcacacacagtatcagctacctgccccaggtg
gatgtcatcatcgtcatgactggaggcaagatctccgagatgggctcctaccaggagctg
ctggcccgggacggggcctttgccgagttcctgcgcacgtacgccagcaccgagcaggag
cagtccgagcaggatgacggcatcagtagtcccgggaaggagacgaagcagatggagaat
ggcatgctggtgacggacgtcgcggggaagcagctgcagagacagctgagcaactcttcc
tcctacagcggggacgttagccgccaccacacgagcaccgctgagccgcagaaagctgga
gcccaggacgaggacgcgtggaagctggtggaggcagacaaggctcaaacggggcaggtc
aagctgtccgtgtactgggactacatgaaggccatcggactgttcatcgcctttctgagc
atcttccttttcttgtgcaaccacgttgctgccctggcttctaactattggctcagcctc
tggactgatgaccccatcgtcaacgggacccaggagcacaccaaagtccggctgagcgtc
tacggcgccctgggcatttcgcaaggtatctccgtgttcggctactccatggcgctgtcc
atcggggggatctttgcttcccgccgcctgcacctgaacctgctccagaacgtgctccgg
tcccccatgagcttcttcgagcggacccccagcgggaacctggtgaaccgcttctccaag
gagctggacacggtggactcgatgatccctcaggtcatcaagatgttcatgggctccctg
ttcaacgtcatcggcgcctgcgccatcatcctgctggccacgcccatcgctgccatcatc
atcccgccgctgggcctcatctacttcttcgtgcagaggttctacgtggcctcgtcccgg
cagctgaaacgcctcgagtccgtcagccgctccccagtgtattcccacttcaatgagacc
ctgctgggggtcagcgtcatccgcgccttcgaggaacaggagcgcttcatccgccagagc
gacctgaaggtggacgagaaccagaaggcctattaccccagcatcgtggccaacaggtgg
ctggccgtgcggctggagtgcgtaggcaactgcatcgtcctgtttgctgccctgttcgcc
gtgatctccaggcacagtctcagcgccggcttagtgggcctctcggtgtcctactcactg
caggtcaccacgtacttgaactggctggttcgcatgtcgtccgagttggagaccaacatc
gtggccgtggagagactgaaggagtattcggaaacggagaaggaggctccctggcaaatc
cccgagacggctccgcccagcacctggcctcaggttggccgagtagaattccgagactat
ggcctgcgttaccgggaaaacctggacttggttctcaagcacattaacgtcaccatcgat
ggaggggagaaggttggcatcgtggggcggacaggagcggggaagtcgtccctgaccctg
ggcttgtttcggatcaacgagtctgctgagggagagatcattattgacgacatcaacata
gccaagattggcctacatgatctgcgcttcaggatcaccattatcccacaggaccctgtt
ttgttttcgggttccctgcgcatgaacctggacccgttcagccagtactccgatgaagaa
gtctggacgtccctggagctggctcacctcaaggactttgtgtcagcccttcccgataag
ctgaaccacgagtgtgcagaaggcggggagaacctgagcgttgggcagcgtcagctggtg
tgcctggcccgggctctgctgaggaagacaaagatcctggtcttggatgaggccaccgcg
gctgtggacctcgaaaccgatgacctcattcagtctaccatccggacacagtttgacgac
tgcactgtcctgaccattgctcaccggctcaacaccatcatggactacacaagggtaatc
gtcctagacaaaggagaaatccgggagtgtggccaccccttggacctcctgcaggagaga
ggtcttttctacagcatggccaaagatgctggcctggtgtga |
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