Panthera uncia (snow leopard): 125928028
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Entry
125928028 CDS
T08832
Name
(RefSeq) mitogen-activated protein kinase 3 isoform X1
KO
K04371
mitogen-activated protein kinase 1/3 [EC:
2.7.11.24
]
Organism
puc
Panthera uncia (snow leopard)
Pathway
puc01521
EGFR tyrosine kinase inhibitor resistance
puc01522
Endocrine resistance
puc01524
Platinum drug resistance
puc04010
MAPK signaling pathway
puc04012
ErbB signaling pathway
puc04014
Ras signaling pathway
puc04015
Rap1 signaling pathway
puc04022
cGMP-PKG signaling pathway
puc04024
cAMP signaling pathway
puc04062
Chemokine signaling pathway
puc04066
HIF-1 signaling pathway
puc04068
FoxO signaling pathway
puc04071
Sphingolipid signaling pathway
puc04072
Phospholipase D signaling pathway
puc04114
Oocyte meiosis
puc04140
Autophagy - animal
puc04148
Efferocytosis
puc04150
mTOR signaling pathway
puc04151
PI3K-Akt signaling pathway
puc04210
Apoptosis
puc04218
Cellular senescence
puc04261
Adrenergic signaling in cardiomyocytes
puc04270
Vascular smooth muscle contraction
puc04350
TGF-beta signaling pathway
puc04360
Axon guidance
puc04370
VEGF signaling pathway
puc04371
Apelin signaling pathway
puc04380
Osteoclast differentiation
puc04510
Focal adhesion
puc04520
Adherens junction
puc04540
Gap junction
puc04550
Signaling pathways regulating pluripotency of stem cells
puc04611
Platelet activation
puc04613
Neutrophil extracellular trap formation
puc04620
Toll-like receptor signaling pathway
puc04621
NOD-like receptor signaling pathway
puc04625
C-type lectin receptor signaling pathway
puc04650
Natural killer cell mediated cytotoxicity
puc04657
IL-17 signaling pathway
puc04658
Th1 and Th2 cell differentiation
puc04659
Th17 cell differentiation
puc04660
T cell receptor signaling pathway
puc04662
B cell receptor signaling pathway
puc04664
Fc epsilon RI signaling pathway
puc04666
Fc gamma R-mediated phagocytosis
puc04668
TNF signaling pathway
puc04713
Circadian entrainment
puc04720
Long-term potentiation
puc04722
Neurotrophin signaling pathway
puc04723
Retrograde endocannabinoid signaling
puc04724
Glutamatergic synapse
puc04725
Cholinergic synapse
puc04726
Serotonergic synapse
puc04730
Long-term depression
puc04810
Regulation of actin cytoskeleton
puc04910
Insulin signaling pathway
puc04912
GnRH signaling pathway
puc04914
Progesterone-mediated oocyte maturation
puc04915
Estrogen signaling pathway
puc04916
Melanogenesis
puc04917
Prolactin signaling pathway
puc04919
Thyroid hormone signaling pathway
puc04921
Oxytocin signaling pathway
puc04926
Relaxin signaling pathway
puc04928
Parathyroid hormone synthesis, secretion and action
puc04929
GnRH secretion
puc04930
Type II diabetes mellitus
puc04933
AGE-RAGE signaling pathway in diabetic complications
puc04934
Cushing syndrome
puc04935
Growth hormone synthesis, secretion and action
puc04960
Aldosterone-regulated sodium reabsorption
puc05010
Alzheimer disease
puc05020
Prion disease
puc05022
Pathways of neurodegeneration - multiple diseases
puc05034
Alcoholism
puc05132
Salmonella infection
puc05133
Pertussis
puc05135
Yersinia infection
puc05140
Leishmaniasis
puc05142
Chagas disease
puc05145
Toxoplasmosis
puc05152
Tuberculosis
puc05160
Hepatitis C
puc05161
Hepatitis B
puc05163
Human cytomegalovirus infection
puc05164
Influenza A
puc05165
Human papillomavirus infection
puc05166
Human T-cell leukemia virus 1 infection
puc05167
Kaposi sarcoma-associated herpesvirus infection
puc05170
Human immunodeficiency virus 1 infection
puc05171
Coronavirus disease - COVID-19
puc05200
Pathways in cancer
puc05203
Viral carcinogenesis
puc05205
Proteoglycans in cancer
puc05206
MicroRNAs in cancer
puc05207
Chemical carcinogenesis - receptor activation
puc05208
Chemical carcinogenesis - reactive oxygen species
puc05210
Colorectal cancer
puc05211
Renal cell carcinoma
puc05212
Pancreatic cancer
puc05213
Endometrial cancer
puc05214
Glioma
puc05215
Prostate cancer
puc05216
Thyroid cancer
puc05218
Melanoma
puc05219
Bladder cancer
puc05220
Chronic myeloid leukemia
puc05221
Acute myeloid leukemia
puc05223
Non-small cell lung cancer
puc05224
Breast cancer
puc05225
Hepatocellular carcinoma
puc05226
Gastric cancer
puc05230
Central carbon metabolism in cancer
puc05231
Choline metabolism in cancer
puc05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
puc05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
puc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
125928028
04012 ErbB signaling pathway
125928028
04014 Ras signaling pathway
125928028
04015 Rap1 signaling pathway
125928028
04350 TGF-beta signaling pathway
125928028
04370 VEGF signaling pathway
125928028
04371 Apelin signaling pathway
125928028
04668 TNF signaling pathway
125928028
04066 HIF-1 signaling pathway
125928028
04068 FoxO signaling pathway
125928028
04072 Phospholipase D signaling pathway
125928028
04071 Sphingolipid signaling pathway
125928028
04024 cAMP signaling pathway
125928028
04022 cGMP-PKG signaling pathway
125928028
04151 PI3K-Akt signaling pathway
125928028
04150 mTOR signaling pathway
125928028
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
125928028
04148 Efferocytosis
125928028
09143 Cell growth and death
04114 Oocyte meiosis
125928028
04210 Apoptosis
125928028
04218 Cellular senescence
125928028
09144 Cellular community - eukaryotes
04510 Focal adhesion
125928028
04520 Adherens junction
125928028
04540 Gap junction
125928028
04550 Signaling pathways regulating pluripotency of stem cells
125928028
09142 Cell motility
04810 Regulation of actin cytoskeleton
125928028
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
125928028
04613 Neutrophil extracellular trap formation
125928028
04620 Toll-like receptor signaling pathway
125928028
04621 NOD-like receptor signaling pathway
125928028
04625 C-type lectin receptor signaling pathway
125928028
04650 Natural killer cell mediated cytotoxicity
125928028
04660 T cell receptor signaling pathway
125928028
04658 Th1 and Th2 cell differentiation
125928028
04659 Th17 cell differentiation
125928028
04657 IL-17 signaling pathway
125928028
04662 B cell receptor signaling pathway
125928028
04664 Fc epsilon RI signaling pathway
125928028
04666 Fc gamma R-mediated phagocytosis
125928028
04062 Chemokine signaling pathway
125928028
09152 Endocrine system
04910 Insulin signaling pathway
125928028
04929 GnRH secretion
125928028
04912 GnRH signaling pathway
125928028
04915 Estrogen signaling pathway
125928028
04914 Progesterone-mediated oocyte maturation
125928028
04917 Prolactin signaling pathway
125928028
04921 Oxytocin signaling pathway
125928028
04926 Relaxin signaling pathway
125928028
04935 Growth hormone synthesis, secretion and action
125928028
04919 Thyroid hormone signaling pathway
125928028
04928 Parathyroid hormone synthesis, secretion and action
125928028
04916 Melanogenesis
125928028
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
125928028
04270 Vascular smooth muscle contraction
125928028
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
125928028
09156 Nervous system
04724 Glutamatergic synapse
125928028
04725 Cholinergic synapse
125928028
04726 Serotonergic synapse
125928028
04720 Long-term potentiation
125928028
04730 Long-term depression
125928028
04723 Retrograde endocannabinoid signaling
125928028
04722 Neurotrophin signaling pathway
125928028
09158 Development and regeneration
04360 Axon guidance
125928028
04380 Osteoclast differentiation
125928028
09159 Environmental adaptation
04713 Circadian entrainment
125928028
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
125928028
05206 MicroRNAs in cancer
125928028
05205 Proteoglycans in cancer
125928028
05207 Chemical carcinogenesis - receptor activation
125928028
05208 Chemical carcinogenesis - reactive oxygen species
125928028
05203 Viral carcinogenesis
125928028
05230 Central carbon metabolism in cancer
125928028
05231 Choline metabolism in cancer
125928028
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
125928028
09162 Cancer: specific types
05210 Colorectal cancer
125928028
05212 Pancreatic cancer
125928028
05225 Hepatocellular carcinoma
125928028
05226 Gastric cancer
125928028
05214 Glioma
125928028
05216 Thyroid cancer
125928028
05221 Acute myeloid leukemia
125928028
05220 Chronic myeloid leukemia
125928028
05218 Melanoma
125928028
05211 Renal cell carcinoma
125928028
05219 Bladder cancer
125928028
05215 Prostate cancer
125928028
05213 Endometrial cancer
125928028
05224 Breast cancer
125928028
05223 Non-small cell lung cancer
125928028
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
125928028
05170 Human immunodeficiency virus 1 infection
125928028
05161 Hepatitis B
125928028
05160 Hepatitis C
125928028
05171 Coronavirus disease - COVID-19
125928028
05164 Influenza A
125928028
05163 Human cytomegalovirus infection
125928028
05167 Kaposi sarcoma-associated herpesvirus infection
125928028
05165 Human papillomavirus infection
125928028
09171 Infectious disease: bacterial
05132 Salmonella infection
125928028
05135 Yersinia infection
125928028
05133 Pertussis
125928028
05152 Tuberculosis
125928028
09174 Infectious disease: parasitic
05145 Toxoplasmosis
125928028
05140 Leishmaniasis
125928028
05142 Chagas disease
125928028
09164 Neurodegenerative disease
05010 Alzheimer disease
125928028
05020 Prion disease
125928028
05022 Pathways of neurodegeneration - multiple diseases
125928028
09165 Substance dependence
05034 Alcoholism
125928028
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
125928028
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
125928028
04933 AGE-RAGE signaling pathway in diabetic complications
125928028
04934 Cushing syndrome
125928028
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
125928028
01524 Platinum drug resistance
125928028
01522 Endocrine resistance
125928028
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
puc01001
]
125928028
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
puc03036
]
125928028
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
puc04147
]
125928028
Enzymes [BR:
puc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
125928028
Protein kinases [BR:
puc01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
125928028
Chromosome and associated proteins [BR:
puc03036
]
Eukaryotic type
Centromeric chromatin formation proteins
SAC (spindle assembly checkpoint) factors
Protein kinases
125928028
Exosome [BR:
puc04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
125928028
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
APH
Haspin_kinase
Choline_kinase
FTA2
Kdo
Motif
Other DBs
NCBI-GeneID:
125928028
NCBI-ProteinID:
XP_049494507
LinkDB
All DBs
Position
E3:16937135..16943346
Genome browser
AA seq
410 aa
AA seq
DB search
MAAAAAQGGGGGEPGGADGVGPGVSGEVEVVKGQPFDVGPRYTQLQYIGEGAYGMVSSAY
DHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRAPTLEAMRDVYI
VQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL
KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSD
AKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEVGQPPATGLVGRWMGKRPSVP
GLSLTSLLPQPVAEEPFTFDMELDDLPKERLKELIFQETARFQPGALEAP
NT seq
1233 nt
NT seq
+upstream
nt +downstream
nt
atggcggcggcggcggctcaggggggcgggggcggggagcccgggggagctgatggggtc
ggcccgggggtctcgggggaggtggaggtagtgaaggggcagccgttcgacgtgggcccg
cgctacacgcagctgcagtacatcggcgagggcgcgtacggcatggtcagctcagcttat
gaccacgtgcgcaagactcgcgtggccatcaagaaaatcagccccttcgagcatcagacc
tactgccagcgcacgctgcgggagatccagatcctgctgcgcttccgccatgagaacgtc
attggcatccgggacattctgcgggcgcccaccctggaagccatgagggatgtctacatt
gtgcaggacctgatggagacagacctgtacaagttgctcaaaagccagcagctgagcaac
gaccacatttgctacttcctctaccagatcctgcggggcctcaagtatatccactcagcc
aacgtgctccaccgggatttaaagccctctaacctgctcatcaacaccacctgcgacctt
aagatctgtgattttggcctggcccggattgccgatcctgagcatgaccacactggcttc
ctgacagaatatgtggccacacgctggtaccgggctccagaaatcatgcttaattccaag
ggctacaccaagtccatcgacatctggtctgtgggctgcattctggctgagatgctctcc
aacaggcccatcttccctggcaagcactacctggaccagctcaaccacattctggggatc
ctgggctccccatcccaggaggacttgaattgtatcatcaacatgaaggcccgaaactac
ctacagtctctgccctccaagaccaaggtggcctgggccaagctttttcccaagtcagat
gccaaagccctggatctgctagaccggatgttgacctttaaccccaacaaacggatcaca
gtggaggaagcactggctcacccctacctggagcagtactacgacccaacggatgaggtg
ggccagccaccagcaacagggctggtgggtagatggatgggtaagcgaccctcagtgcct
ggcctgagcctgacttctttactaccccagccagtggccgaggagcctttcaccttcgac
atggagctggatgatctacccaaggagcggctgaaggagctcatcttccaggagacagcc
cgcttccagcctggggcactggaggccccctaa
DBGET
integrated database retrieval system