Panthera uncia (snow leopard): 125928821
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Entry
125928821 CDS
T08832
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
puc
Panthera uncia (snow leopard)
Pathway
puc00310
Lysine degradation
puc01100
Metabolic pathways
puc05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
puc00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
125928821
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
125928821
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
puc03036
]
125928821
Enzymes [BR:
puc01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
125928821
Chromosome and associated proteins [BR:
puc03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
125928821
HMT complexes
Dot1-containing complex
125928821
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
HALZ
Motif
Other DBs
NCBI-GeneID:
125928821
NCBI-ProteinID:
XP_049495514
LinkDB
All DBs
Position
A2:1181188..1242225
Genome browser
AA seq
1692 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTATPTKVP
ESKAAVAADTPVDSGAEEEKAGTTAIKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMSAA
NPERKPRKSQTALDLLHAPASSQTAAPSPQDAYRSPHSPFYQLPPCVQRHAPDRPLLAAT
PPALQKLLESFKIQYLQFLAYTKTAQYKASLQQLLDQEKEKNARLLGAAQQLFGHCQAQK
EEIKRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQTEQLQEDNRELRSQSLQLL
KARCEELKLDWSTLSLENLLKEKQALRSQISEKQRHCLELQISIVELEKSQRQQELLQLK
SCVPPDDALPAHLRGKGALGREPEADPGRLHLDLDCSRFSLPHFSSASPELSMNGHAASY
ELCGALSRPPSKQNTPQYLASPLDQEVVPCTPSHGSRPRLEKVSGLALPDYTRLSPAKLV
LRRHLSQDHAAGGKTAAGELHPRAEHAKENGLPYQSPGIANGIKLSPQDPRPSSPVALQM
TGERGGEKGLKERAYASSGEAITSLPVSIPLSTVQPSKLPVSIPLASVVLPSRAEKVRST
PSPVPQTRESLSTLEKQMGTNAHSAGSKSLAPAPAGFYAGSVAVSPAPLASGADPGTSDE
VPSAGGLFASVGSCGSTPQHPPLLPQPRSSGAASPAHPLCASPRLGGAAQGPLPDANKGD
LPPEAGFSDPEGEAKRRIVFTVSAGGGSTKQSPPSKPSPLPTGGRGDGSQGHGQDSRKRG
RRKRAAAGTPGLSSGVSPKRRALPSVAGLFTQSSGSPLNLNSMVSNINQPLEITAISSPE
SLKSSPVPYQDSDQPPVLKKEKPLSQTNGAHYSPLTSDEEQGSEDEPGSTRIERKIATIS
LESRSPPKTLENGGGLAGRKPPPAGEPANSSKWKSTFSPISDLGLAKCADSPLQAGSALS
HNSLFAFRPPLEEPGSADAKLAAHPRKSFPGALSGAGGLSPSSNPPNGFAFSGGLAADLS
LHSFSDGASLSHKVPEAAGLGAPLSFPAPRGKDSAAEPGPFVNKRQLDGAGGPKGREAGE
PGPPACGPPDKASLAHGKPGKGRDREPDLKNGHNLFIAAANVPPGGLLSGPGLATAASSV
VSAAPSAQAHRPFLGTFAPGPQFALGPMSLQANLGSSVLQSLFGSVPAAGLVHVSSAATR
LTNSHAMGSFPSGVAGGAVGGVFNHAVPSASAHPFGASFGSGAACRSATLSLTPLQAVAG
APPPPPPGQPALPAPPPPNAALPPAPALLPANSEPALLQNLASLPANQAFLPASSAASLQ
PANASLSIKLASLPHKAPRPSFTVHHQPLPGLALAQAAPVIPQASSTGPSAVWVSLGMPP
PYAARLAGVKPR
NT seq
5079 nt
NT seq
+upstream
nt +downstream
nt
atgggggagaagctggagctgaggctcaagtcgcccgtaggggccgagcccgccgtctac
ccgtggccgctgccggtctacgacaaacaccacgatgctgctcacgaaatcatcgagacc
atccggtgggtctgcgaagagatcccggacctcaagctcgctatggagaactacgtttta
atcgactacgacaccaaaagcttcgagagcatgcagaggctctgtgataagtacaaccgc
gccatcgacagcatccaccagctgtggaaggggaccactcagcccatgaaactgaacacc
cggccgtccaatgggctcctgcggcacatcctgcagcaggtgtataaccactcggtgacg
gaccccgagaagctcaacaactacgagcccttctccccggaggtgtacggggagacctcc
tttgacctggtcgcgcagatgatcgacgagatcaagatgaccgaggacgacctgtttgtg
gacctgggcagcggagtgggccaggtcgtgctccaggtggccgcggccaccaactgcaaa
catcactacggcgtggagaaagccgacatcccagccaagtacgcggagaccatggaccga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggaaaga
ggcgacttcctctcggaggagtggagagagcgaattgccaacacaagtgttatatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggagcggtttgcgaacatg
aaggaaggtggcagaattgtgtcctcgaagccctttgcgcctctgaacttcagaataaac
agcagaaacttgagcgacatcggcaccatcatgcgcgtcgtggagctctcgcccctgaag
ggctctgtgtcctggacggggaagccagtctcctactacctgcacaccatcgaccgcacc
atacttgaaaactatttttctagtctgaaaaacccaaaactcagggaggagcaagaggcg
gctcggcgccggcagcagcgagagaacaagagcaacacggccactcccaccaaggtgccc
gagagcaaggctgccgtggccgcggacacccccgtggattccggtgccgaggaagagaag
gctgggacgaccgccatcaaaaagccgtccccctccaaagcccggaagaagaagctgaac
aagaaggggcggaaaatggccggcaggaagcgcgggcgccccaagaagatgagcgctgcc
aaccccgagcgcaagccccggaagagccaaactgcactggacctcctgcacgccccggcc
tcgtcgcagacggcggcgccctcgccacaggatgcgtacaggtcacctcatagccccttc
tatcagctacctccctgcgtgcagcggcacgcccccgaccggccgctgctggcagccacc
ccgcccgcactgcagaagctgctagaatccttcaagattcagtacctgcagttcttggcc
tacaccaagaccgcccagtacaaggccagccttcagcagctgctggaccaggagaaggag
aagaacgcccggctgctgggggccgcacagcagctgttcggccactgccaggcccagaaa
gaggagatcaagaggctcttccagcagaaactggatgagctgggggtgaaggcgctgacc
tacaacgacctgattcaggcgcagaaggagatctcggcccataaccagcagctgagggag
cagacagagcagctgcaggaggacaacagggagctgaggagccagagcctgcagctgctc
aaggctcggtgtgaggagttgaaactggactggtccacgctgtcgctggagaacctgctg
aaggagaagcaggccctgaggagccagatctccgagaagcagaggcactgcctggagctg
cagatcagcatcgtggagctggagaagagccagcggcagcaagagcttctgcagctcaag
tcctgcgtgccgcccgacgacgccctgccggcgcacctgcgcgggaaaggcgccctgggc
cgggagccggaggcggaccccggccggctgcacctcgacctggactgctctaggttctcc
ctgccgcacttcagcagcgccagcccggaactctccatgaacggccacgcggccagctac
gagctctgcggtgcgctgagccggcccccgtccaagcagaacaccccccagtacctggcc
tccccgctggaccaggaggtcgtgccctgcacccccagccacggcagccggccgaggctc
gagaaggtgtccggcctggccttgccggactacaccaggctgtccccggccaagctggtg
ctgaggcggcacctcagccaggaccacgcggccggcggcaagacggcggccggggagctg
cacccgcgagccgagcacgccaaggagaacggccttccgtaccagagcccgggcatcgcc
aacggcatcaagctgagccctcaggacccccggccctcgtcccccgtggccttacagatg
acaggggagaggggcggcgagaagggtttgaaggagcgtgcctatgccagcagcggggag
gccatcaccagcctgcctgtcagcatcccgctcagcaccgtgcagcccagcaagctgccc
gtcagcatccctctggccagcgtggtgctgcccagccgtgccgagaaagtgagaagcacc
cccagccccgtgccgcagacccgagagtccttgtccacacttgaaaagcagatgggcact
aatgcacacagcgccggaagcaaaagtcttgccccagcccctgcaggcttctacgcgggc
tcggtggccgtcagcccagccccccttgcttccggagcggatcccggcacctctgacgag
gtccccagcgcgggcggtctgtttgccagcgtggggtcctgtggctccaccccgcagcac
ccgcccctgctgccgcagccccgcagctctggcgcagcctcgcccgcccacccgctctgt
gccagcccccgcctgggtggcgccgcccagggcccgctccctgacgccaacaaaggggac
cttcctcccgaggccggcttctcggaccccgagggcgaagccaagcggaggatcgtcttc
accgtctcggccggcgggggcagcaccaagcagtcgcctcccagcaagcccagccctctg
cccacgggcggccgtggggacggcagccagggccacgggcaggacagccgcaagcggggc
agaaggaagcgggcggcggcagggacccccggcctgagctcaggcgtgtcgcccaagcgc
cgggccctgccgtccgtggccggcctcttcacgcagtcttcagggtcccccctgaacctg
aactccatggttagcaacattaaccagcctttggaaatcacggccatttcgtcccccgag
agcctgaagagctcccctgtcccctaccaggacagcgaccagccgcccgtcctcaagaag
gagaagcccctgagccagaccaacggggcccactactccccactgacctcggacgaggag
cagggctccgaggacgagccgggcagcaccagaattgagagaaaaattgcgacaatctcc
ttagaaagcagatctcctccgaaaaccttggaaaacggtggtggcctggccgggaggaag
ccgccccctgccggcgagcccgccaacagcagcaagtggaagtctaccttttcgcccatc
tccgacctcggcctggccaagtgcgccgacagcccgctgcaggccggctctgccctgagc
cacaactccctgtttgctttccggccgcccctggaggagcccggctcggccgacgccaag
ctggccgcccaccccaggaaaagcttccctggtgccctgtcgggggcaggcgggctgagc
ccaagcagcaaccctcccaacggcttcgccttcagcgggggcctggccgccgacctcagt
ttacacagcttcagtgatggtgcttctctctcccacaaggtccccgaggcggcaggcctg
ggcgcccccctgagctttcccgccccccggggcaaggacagcgctgcagagcctgggccc
tttgtgaacaagaggcagctggacggcgcgggcggccccaagggcagggaggcaggcgag
ccgggccccccggcgtgcgggcccccggacaaggcctcgctggcgcacggcaagccgggc
aagggccgggaccgtgagcccgacctgaagaacggccacaacctcttcattgcggccgcc
aacgtgccccccggcggcctcctcagtggcccgggcctcgccacggcagcgtcctcggtg
gtcagcgcggccccctctgcccaggcgcaccgccccttcctgggcacatttgcccccggc
ccgcagttcgccctgggccccatgtcgctgcaggccaacctgggctcgtctgtgctgcag
tccctgtttggctccgtgccggccgccggcctggtgcacgtctcgtccgccgcaaccaga
ctgaccaactcgcacgccatgggcagctttccctccggggtggcaggcggcgcagttgga
ggtgtctttaaccacgcggtgccttccgcctccgctcatccgtttggagccagtttcggc
agcggggctgcgtgtcgcagcgccacgctgagcttaaccccgctgcaggcggtggccggc
gccccgcccccgcccccaccggggcagcctgccctccccgcgccccctccccctaacgcc
gccttgcctcccgcccccgcactgctccctgctaactctgagcccgcgcttctgcagaac
ctcgcgtccctcccggctaaccaggctttcttacccgcctcctctgccgcctctctgcag
cctgctaacgcctctctgtccatcaagctcgcctccctcccgcacaaggccccccgcccc
tccttcacggtgcaccaccagcccctgcccgggctggccctggcccaggccgcgcccgtg
atcccacaggccagctccacggggccgtccgccgtgtgggtttcccttggcatgccgcct
ccgtatgccgcgcgccttgcgggggttaagccaagataa
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