Panthera uncia (snow leopard): 125930540
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Entry
125930540 CDS
T08832
Name
(RefSeq) cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform X1
KO
K13293
cAMP-specific phosphodiesterase 4 [EC:
3.1.4.53
]
Organism
puc
Panthera uncia (snow leopard)
Pathway
puc00230
Purine metabolism
puc01100
Metabolic pathways
puc04024
cAMP signaling pathway
puc04928
Parathyroid hormone synthesis, secretion and action
puc05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
puc00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
125930540
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
125930540
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
125930540
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
125930540
Enzymes [BR:
puc01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
125930540
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
PDE4_UCR
Emfourin
Motif
Other DBs
NCBI-GeneID:
125930540
NCBI-ProteinID:
XP_049498341
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Position
A2:7192646..7228231
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AA seq
871 aa
AA seq
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MEPPAAPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERAEPERP
PHRPIERADAVDTGDRPGLRTSRMSWPSSFHGTGTGSGGASGGSCKRFEAENGPTPSPGR
SPLDSQASPGLVLHAGGAISQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTP
FAQVLASLRSVRSNFSLLTNVPIPSNKRSPLGGPTPVCKATLSEETCQQLARETLEELDW
CLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEI
PSPTMKDREKQPAPRQRPSQQPPPPGPQFQPMSQITGVKKLMHSSSLSDSSIPRFGVKTN
QEELLAQELENLNKWGLNIFCVSEYAGGRSLSCIMYTIFQERDLLKKFRIPVDTMVTYML
TLEDHYHPDVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGV
SNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDM
VLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLE
LYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADL
VHPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEEPRGPGHPPPPDKFQFELTLEEEDEEE
VSTAPGAFTVQGLSVAQDASPAEELLEVDGQDMPTEVKVQEPCCTQQADSAGSVAAGKDK
ATSPDASVDAVGRSSPLALSAESPLPPALRTPPPPEDTPGLPGLPSTAAEAGAQKEHQAA
KRACSACTGTSGEDPPPLPAPGGWGSAGGPT
NT seq
2616 nt
NT seq
+upstream
nt +downstream
nt
atggagcccccggccgccccttcggagaggagcctgtctctgtctctgcccgggccccgg
gagggccaggccaccctgaagccgcccccacagcacctgtggcggcagccgcggacccct
atccgtatccagcagcgcggctactctgacagcgcggagcgcgcagagcccgagcggccg
ccacaccggcccatagagcgcgccgacgccgtggacaccggcgaccggcccggcctgcgc
acttctcgcatgtcctggccctcgtccttccacggtaccggcaccggcagcggcggcgcg
agcggaggcagctgcaagcgcttcgaggcggagaatgggcccacgccatctcctggccgc
agccccctggactcgcaggcgagcccgggcctcgtgctgcacgccgggggggctatcagc
cagcgccgggagtccttcctgtaccgctcggacagtgactatgacatgtcacccaaaacc
atgtcccggaactcgtcggtcaccagcgaggcgcacgctgaggacctcattgtgacacct
ttcgcccaggtgctggccagtctccggagtgttcgcagcaacttctcactcctgaccaat
gtgcccattcccagcaacaaacggtccccgctgggcggcccaacccccgtctgcaaggcc
acgctgtcagaagagacatgtcaacaattggcccgggagacactggaggagctggactgg
tgcctggagcagctggagaccatgcagacctaccgctccgtgagcgagatggcatctcac
aagttcaagaggatgttaaaccgtgaactcacacacctgtcagagatgagcaggtcagga
aaccaggtctctgagtacatctccaccacattcctggacaagcagaatgaagtggagatt
ccatcacccacgatgaaggatcgagaaaaacagccagctccccgccagagaccttcccag
cagcccccgccccccgggccgcaattccagcccatgtctcagatcacgggggtgaagaag
ctgatgcatagcagcagcctgagtgactccagcatcccccgctttggggtgaagaccaac
caagaagagctcctggcccaagaactggagaacctgaacaagtggggcctgaacatcttc
tgcgtatccgaatacgccggaggccgttccctcagctgcatcatgtacacgatatttcag
gagcgtgacctgctgaagaaattccgcatcccagtggacaccatggtgacatatatgctg
accctggaggaccactaccaccccgacgtggcctaccacaacagcctgcacgcggccgat
gtgctgcagtccacccacgtgctgctggccacacccgcgctagatgctgtgttcacggac
ctggagattcttgccgccctcttcgcggccgctattcatgacgtagaccaccctggtgtc
tccaaccagttcctcatcaacactaattcggagctggcgctcatgtacaacgatgagtcg
gtgctggagaaccaccacctggccgtgggcttcaagctgctgcaggaagacaactgcgat
atcttccagaacctcagcaagcgccagcggcagagcctgcgcaagatggtcatcgacatg
gtgctggccacggacatgtccaaacacatgaccctcctggcagacctgaagaccatggtg
gagaccaagaaggtgaccagctcgggggtcctcctgctggacaactactccgaccgcatc
caggtccttcggaacatggtgcactgtgcagacctcagcaaccccaccaagccactcgag
ttgtaccgccagtggaccgaccgcattatggccgagttcttccagcagggggaccgtgaa
cgtgagcggggcatggagatcagccccatgtgcgacaagcacacagcctcggtggagaag
tctcaggtgggtttcatcgactatatcgtgcacccgctgtgggagacgtgggctgacctg
gtccacccggacgcccaggagatcctggacacgttagaggacaacagagactggtactac
agcgccattcggcagagcccatcaccgccgcctgaggaggagcccagggggccaggccac
ccacccccacctgataagttccagttcgagctgacgctggaagaggaagatgaggaggag
gtgtctaccgccccgggtgcatttacggtgcagggattgtccgtggctcaggatgcgtcc
ccagctgaggaactcttggaggtcgatggccaggatatgcccacggaggtgaaggtacag
gaaccttgctgcacgcagcaagcagactcggccggtagtgtggctgcgggcaaggacaag
gccacgtccccagacgcatctgtggatgccgtaggccgcagcagccccctggccttgtct
gccgagagcccccttccgcccgccttgaggaccccaccccctccagaggacaccccgggc
ctcccgggcctcccctccacggcggccgaggcgggggcccaaaaagagcatcaggctgcc
aagagggcgtgcagtgcctgcacaggaacgtccggcgaggacccccccccactcccagct
cctggggggtgggggtcagctggaggccctacctga
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