Panthera uncia (snow leopard): 125933392
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Entry
125933392 CDS
T08832
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
puc
Panthera uncia (snow leopard)
Pathway
puc00562
Inositol phosphate metabolism
puc01100
Metabolic pathways
puc04014
Ras signaling pathway
puc04015
Rap1 signaling pathway
puc04020
Calcium signaling pathway
puc04024
cAMP signaling pathway
puc04070
Phosphatidylinositol signaling system
puc04919
Thyroid hormone signaling pathway
puc04933
AGE-RAGE signaling pathway in diabetic complications
puc05205
Proteoglycans in cancer
Module
puc_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
puc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
125933392
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
125933392
04015 Rap1 signaling pathway
125933392
04020 Calcium signaling pathway
125933392
04070 Phosphatidylinositol signaling system
125933392
04024 cAMP signaling pathway
125933392
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
125933392
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
125933392
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
125933392
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
puc04131
]
125933392
Enzymes [BR:
puc01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
125933392
Membrane trafficking [BR:
puc04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
125933392
Endocytosis
Macropinocytosis
Phospholipase C
125933392
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
EGF_Pikachurin
Motif
Other DBs
NCBI-GeneID:
125933392
NCBI-ProteinID:
XP_049502364
LinkDB
All DBs
Position
D2:52158850..52480749
Genome browser
AA seq
2301 aa
AA seq
DB search
MTSEEMAASVLTPVTQRKVKSSPSALDESSEKVSDVSVPKAHSVRQSGQTSTISRLNKLK
EESSGSNLPKIVSIAREKIMSDENSNEKYWEESMPDSVKNLNINCNNVLKNSQCSLPQSQ
CYDTCDSVMEEGLCLETGIPSSLERKVFPGIQLEVDGPPMDISPLGNQSAIIESGRAHPD
GSMAAFHFHYEVDRRMSDTFCTLSDNLILDDCGNCVPLPGVRGERQKNYMAYTCKLMELA
ENCDNKNGQLQCDHCDALNDRYLCFEASCQRANAVCSSDSFCREDFTNSPPAKTFLSHFE
DFPDNCEDVEEDFFKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIMRTLPSGHIGLGAY
SYIDQKRSGLLLPCGRVLERRSAVAVREDGSWCLSEAQWYSIYNAVRRREEIENTIGSLI
HFFTKLPASETAHERIRVGPCLKQCVRDTICEYRATLQRTSISQYIVGSLLEATTSLGAR
SGLLSTFGGSTGRMMLKERQPGTSMANSSALPSSSAGISKELIDLQPLIQFPEEVASILM
EQEQNIYRRVLPVDYLCFLTRDLGSPECQTSLPCLKASISASILNSQNGEHNALEDLVMR
FNEVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMW
QFMDQSDLETMRSLKDAMAQHESSCEYKKVVTRALHIPGCKVVPFCGVFLKELCEVLDGA
SGLMKLCPRYNSQEETLEFVADYSGQDNFLQRVGHNGLKNSEKESTVNSIFQIIRSCSRS
LEAEEEDSPSEGNSSRKNSLRDKARWQFIIGDLLDSENDIFEKSKEWDAHGSEEPQKAFD
HGTELIPWYVLSIRADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWTKPTTAS
LASAKAKLGVLSNTSEPGKFPLLGNAGLSGLAEGVLDLFSAKAVYMGHPSIDIHTVCVQN
KLGSMFLSETGVTLLYGLQTTDNRLLHFVAPRHTAKMLFSGLLELTRAVRKMRKFPDQRQ
QWLRKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSTRNPSPGTSAKSAEKPNVQRNNTLG
ISTTKKKKKILIRGESGEAADDEMATRKAKMHRECRSRSGSDPQDMNEQEESEANAIMSP
PNTLPSRRAHSLTTAGSPNLSAGTSSPNRPVSSPVLSSSNKSPSSAWSSSSWHGRIKGGM
KGFQSFMVSDSNMSFVEFVELFKSFSVRSRKDLKDLFDVYAVPCNRAGSESVPLYTNLTI
DENTSDLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGVESTSLG
VFGVGILELNDFLVNCQGEHCTYDEILSIIQKFEPSVSMCHQGLLSFEGFARFLMDKDNF
ASKNDESQENIKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDC
WDGDDGLPIIYHGHTLTTKIPFKEVVEAIERSAFVNSDLPIIISIENHCSLPQQRKMAEI
FKSVFGEKLVAKFLFESDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLA
SMQAQAYNGGNANPPPANNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEYN
EEIPKRIKKADNSACNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPGL
STLNASGSSRGKERKSRKSIFGNNPGRMSPGETASFNKASGKSSCEGMRQAWEESSSPLN
PTTSLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPAATRIDSSNPN
PLMFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLE
RDLDNMEPAIYSLTIVSGQNVCPSSSTGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMW
NEQFLFRVHFEDLVFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISS
LFINSRRMEENSSSSTTPASLMFNSEERKCLQAHRVTVHGVPGPEPFTVFSISGGTKAKQ
LLQQILTIEQDTKPIITDYFLMEEKYFISKEKNECRKQPFQRVIGPEEEIMQILSSWFPE
EGYVGRIVLKTQQENLEEKSIVHDDKEVTLSSEEESFFVQVHDVSPEQPRTVIKAPRVST
AQDVIQQTLCKAKYSYSILSNPNPSDYVLLEEVVKDTTKKSSTPKSSQRVLLDQECVFQA
QSKWKGAGKFILKLKEQVQASREDKRKGISFASEFKKFTKSTKQPRGLASPSQVLASEGV
QNKEEKPMGSLSSGDTMEYRQ
NT seq
6906 nt
NT seq
+upstream
nt +downstream
nt
atgacttctgaagaaatggcagcttctgttctcacacctgtgactcagagaaaggtgaaa
tcgtctccgtcggctttagatgaaagtagtgaaaaggtctcagacgtcagtgttccaaag
gcacatagtgtcaggcagagtggtcagacttccaccatctcacgactcaacaagcttaaa
gaagaatcctctggaagcaacttgcccaagattgtctccatagcaagggagaagataatg
agtgatgagaacagcaatgagaagtactgggaggaaagcatgccagattctgtgaaaaac
ctcaatattaactgcaacaacgtactgaaaaacagccagtgcagccttcctcagagccag
tgttatgacacgtgcgattctgtcatggaggaaggcctgtgtttggaaactggaatccca
tcctcactggaaagaaaggtgttccctggaattcaactggaagtggatggacctcccatg
gacattagtcccttaggaaatcagtcggccatcatagagagcggccgggcacaccctgac
ggcagcatggcagcatttcactttcattatgaagtcgacagaagaatgtcagacactttc
tgtaccttgtcagacaacctgattttggatgattgtggtaactgtgtaccactgcctggt
gttcgtggggagcgacagaaaaattatatggcatatacttgtaaactcatggaattggca
gaaaactgtgataataagaatgggcagctgcagtgtgatcattgtgacgccttaaatgac
agatacttgtgcttcgaagcttcttgccaaagggccaatgcggtgtgttcaagtgacagc
ttttgcagggaggactttactaacagtccacctgccaagacctttctgagccattttgag
gacttccctgataattgtgaagatgtagaagaagatttttttaagagcaaaaaggagagg
tccactttgttagtgagaagattttgtaaaaatgacagggaagtaaagaaatctgtatat
actgggacaagggcgatcatgagaactctgccttctggtcacattgggctgggagcttac
agttacattgatcagaagagaagtggtctcctgctgccctgtgggagagttctggaacgg
cggtcagcggtggcagttagggaagatgggagctggtgcctgtcagaagctcagtggtat
tcgatctacaatgcagtgagaaggagagaagaaatagaaaatacaattggatctcttatt
catttcttcacaaagcttccagcctccgaaacagcccatgaaaggattagggttggtccg
tgcttaaagcaatgtgtccgagataccatatgtgagtaccgtgccaccctccagaggacg
tccatatctcagtacatcgtgggttctctgctagaagcaaccacatctttaggagcaaga
agtggcctactcagtacctttggaggatccaccggacgaatgatgctaaaagaacgtcag
ccaggcacctccatggccaattctagtgccctcccttcaagttcagctgggatcagcaag
gagctgattgatctgcagcccctcattcagttcccagaggaagtcgccagcatcctgatg
gagcaggagcagaacatttaccgaagggtcttgccagttgactacctttgcttcttgacc
cgggacttgggctctccagaatgccagacatccctgccctgcctcaaagcgtccatctca
gcatcaattcttaactcccagaacggagaacacaatgccctggaagatcttgtgatgaga
tttaatgaggtgagctcctgggtaacgtggctgatcctcacggcgggctccatggaggag
aagcgagaagtcttctcctatttggtgcacgtggccaaatgctgctggaacatgggcaac
tacaatgctgtcatggagttcttggccggcctcaggtcaagaaaagttttaaaaatgtgg
cagtttatggaccagtctgacctagagaccatgaggagcctgaaggatgccatggctcag
cacgaatcttcctgcgagtacaagaaggtggtcacgcgggctctgcacatacctggctgt
aaggtggttccgttctgtggggtgtttctgaaggagctctgtgaagtactggacggagcc
tccggcctcatgaagctttgcccgaggtacaattcccaagaagaaactctagagtttgta
gccgattacagcggacaagataatttcttacaacgagtgggacataatggcttaaagaat
tcggagaaagagtccacagtcaacagcatctttcagatcatcaggagctgcagccgaagt
ctggaggccgaggaggaggacagccccagtgaaggaaacagctccaggaaaaattcctta
agggataaagcccgatggcagtttatcattggagacctgttagattctgaaaatgacatc
tttgagaaatccaaagaatgggacgctcacggatcagaagagccacagaaggcctttgac
catgggacagagctaatcccatggtacgtgctgtccatccgagccgatgtgcaccagttc
ctgctgcagggggccactgtcatccactacgaccaggacacgcacctctctgcccgatgc
ttcctccagcttcagcctgacaacagcaccttgacctggacaaagcccaccactgcttcc
ctggccagtgctaaagcaaaactcggtgtgcttagtaacacgtctgagcctggcaaattc
ccgttactgggcaatgctggactaagtggcctggcagagggggtcttggatctgttctca
gccaaagctgtgtacatgggacaccctagcatcgatatacacactgtgtgtgttcagaac
aaactgggtagcatgtttctctcagagactggcgtgacgctgctctatgggctccagacc
acggacaatagattattgcactttgtggcacccaggcacacagctaagatgctcttcagt
ggattgctggaactcacgagagccgtgaggaagatgaggaagttccctgaccagagacag
cagtggctgcggaaacagtacgtcagcctctatcaggaagatggacggtacgaaggccca
actttggctcacgccgtggagttgtttggtggcaggcggtggagtacacgaaaccccagc
cccgggacatcagcaaagagtgccgagaagcccaatgtgcaaagaaacaacaccttgggc
ataagcactaccaagaaaaagaagaaaatccttataaggggtgagagtggagaggcagcc
gacgatgaaatggccacccgaaaagccaaaatgcacagagagtgtcgcagccggagtggt
tctgaccctcaagacatgaatgaacaagaagaatcagaggcaaatgccatcatgagccct
cctaacactctgccttccagaagagcccactctttgaccacggctgggtcccctaacttg
tctgccgggacatcatctcccaacaggccagtgtcttcccctgtgctgtcttcttcaaac
aagagcccgtccagtgcttggagcagcagcagctggcacgggcggatcaaaggcggaatg
aaaggtttccagagcttcatggtttcagacagtaacatgagctttgttgaattcgttgag
ctgttcaaatcattcagcgtgaggagccgcaaggacctgaaggacctcttcgacgtctac
gccgtgccctgcaaccgagccggctccgagtcggtgccgctctacaccaacctaacaatt
gacgaaaacaccagtgatcttcagcctgacctagatttattgaccagaaatgtctcggat
ttggggttgttcattaagagtaaacagcagctgtcagacaaccagaggcagatatctgat
gccattgctgctgcaagtatcgtgacaaacggcactggggtcgagagcacatccttgggc
gtgtttggggttggcatcctcgagctcaatgactttctagtgaactgccaaggagaacac
tgcacttatgatgaaatcctcagcatcatccagaagttcgagcctagcgttagtatgtgt
catcagggcctactgtcatttgaaggatttgcaaggtttctgatggataaagataatttc
gcctccaaaaatgatgagtcacaggaaaacattaaagaactacagctgcccctctcctac
tattacattgaatcttcacacaatacctacctcacaggccaccagctcaaaggagagtcc
tcagtagaactctacagccaggtcctcctgcaaggctgtaggagcgtagagctggattgt
tgggatggagacgacgggttgcccatcatctatcatggacacacgctgacaaccaagatc
cccttcaaggaggtggttgaagccattgaacgcagtgcctttgtcaactctgacctgccc
atcatcatatcgattgagaaccactgctcattgcctcagcaacgaaaaatggcagaaatt
ttcaagagtgtgtttggagaaaaactggtggctaagttcctgtttgagagtgatttctca
gatgacccaatgcttccctcacccgaccaacttaggaggaaagtgctccttaaaaataag
aagctaaaagcccaccaaacaccagtggatatcttaaagcaaaaggctcatcagttagca
tccatgcaagctcaggcttacaatggtgggaatgccaaccccccaccggctaataacgag
gaagaggaggatgaagaagacgaatatgattacgactatgaatccctgtctgatgacaac
attctagaagacagacctgaaaataaatcatgtaatgacaagcttcagtttgagtataat
gaagaaatccccaagaggataaagaaagcagataactctgcttgcaacaaaggaaaggtt
tatgacatggaactgggagaagagttttatctccctcagaataaaaaagaaagcagacag
attgcaccagagctctctgaccttgtcatctattgccaagcagtaaaatttccaggcctg
tcaactctaaatgcatctggctctagcagaggaaaagaaaggaaaagcaggaagtccatt
tttggcaacaatccgggcagaatgagccctggggagacagcatcgtttaacaaagcatct
ggaaaaagttcctgtgaaggaatgcgacaggcctgggaggaatcttcttcccccctcaac
ccaaccacatccctcagcgctatcattagaactcccaaatgttaccatatctcctcgctg
aatgaaaatgccgccaaacgtctgtgtcgcaggtattctcagaaactgatccagcacacc
gcctgtcagctgctgaggacttacccggctgccactcgcatcgactcctccaaccccaat
cccctcatgttctggctccatgggatacagctcgtggcgctcaactaccagacagatgat
ctccctttacatttaaatgctgccatgtttgaagccaacggtgggtgtggttatgttttg
aaacccccagttctgtgggacaagaactgtcccatgtatcagaagttctctcccttagaa
agagatctggacaacatggagcctgccatctactccttaactattgtctctggtcaaaac
gtgtgcccgagtagcagcacaggaagcccgtgtatcgaagtcgatgtgctgggcatgccc
ctggacagctgccatttccgcacaaagcccatccaccggaacactctgaaccccatgtgg
aatgaacagtttctcttccgggttcactttgaagatctcgtatttcttcgttttgccgtt
gtggaaaacaacagctcagctgtaactgctcagagaatcatcccactcaaggctttaaaa
cgaggatatcgacatcttcagctgcgaaatcttcacaacgaagtcttggaaatctctagt
ttattcataaacagtaggaggatggaagaaaattcctccagcagcaccacgccggcctct
ttgatgtttaattcagaagaaagaaaatgtttgcaggctcacagagtcacggtgcatggg
gtcccaggtccagagccctttactgttttctccataagtggaggcaccaaagcaaagcag
cttctccaacaaattctgaccattgaacaagacaccaaacctatcatcacagactatttt
ttgatggaagaaaaatattttatatctaaagaaaagaatgaatgcaggaaacaaccgttc
cagagagtcattggtccagaggaagagattatgcagattttaagcagctggtttccagag
gaaggatatgttggcaggattgtcttaaaaacccagcaggaaaacctagaagagaaaagc
attgttcacgatgacaaagaggtgaccttgagctcagaggaggagagtttctttgttcaa
gtgcacgatgtttctccagagcaacctcgaacggtcatcaaagcaccccgtgtcagcacc
gcacaggacgtcattcagcagaccttatgcaaagcaaagtattcctacagcatcctgagc
aatcccaacccaagtgactatgtgcttttggaagaggtggtaaaagacacgaccaagaag
tcttccaccccaaagtcctcccagcgggtccttttggatcaggagtgtgtgtttcaagcc
caaagcaagtggaaaggggcaggaaaattcatccttaagctaaaggagcaggtgcaggca
tcccgagaagacaaaaggaaaggcatttcttttgcaagtgaatttaagaagttcaccaag
tcaactaaacaaccccgaggactcgcatcaccttctcaggtcttggcctcagaaggtgtc
caaaacaaggaggagaaacctatgggcagcttgtcctccggtgacaccatggagtatcga
caataa
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integrated database retrieval system
