KEGG   Panthera uncia (snow leopard): 125937868
Entry
125937868         CDS       T08832                                 
Name
(RefSeq) mitogen-activated protein kinase 14 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
puc  Panthera uncia (snow leopard)
Pathway
puc01522  Endocrine resistance
puc04010  MAPK signaling pathway
puc04015  Rap1 signaling pathway
puc04068  FoxO signaling pathway
puc04071  Sphingolipid signaling pathway
puc04114  Oocyte meiosis
puc04148  Efferocytosis
puc04218  Cellular senescence
puc04261  Adrenergic signaling in cardiomyocytes
puc04370  VEGF signaling pathway
puc04380  Osteoclast differentiation
puc04550  Signaling pathways regulating pluripotency of stem cells
puc04611  Platelet activation
puc04613  Neutrophil extracellular trap formation
puc04620  Toll-like receptor signaling pathway
puc04621  NOD-like receptor signaling pathway
puc04622  RIG-I-like receptor signaling pathway
puc04625  C-type lectin receptor signaling pathway
puc04657  IL-17 signaling pathway
puc04658  Th1 and Th2 cell differentiation
puc04659  Th17 cell differentiation
puc04660  T cell receptor signaling pathway
puc04664  Fc epsilon RI signaling pathway
puc04668  TNF signaling pathway
puc04670  Leukocyte transendothelial migration
puc04714  Thermogenesis
puc04722  Neurotrophin signaling pathway
puc04723  Retrograde endocannabinoid signaling
puc04728  Dopaminergic synapse
puc04750  Inflammatory mediator regulation of TRP channels
puc04912  GnRH signaling pathway
puc04914  Progesterone-mediated oocyte maturation
puc04917  Prolactin signaling pathway
puc04926  Relaxin signaling pathway
puc04932  Non-alcoholic fatty liver disease
puc04933  AGE-RAGE signaling pathway in diabetic complications
puc04935  Growth hormone synthesis, secretion and action
puc04936  Alcoholic liver disease
puc05014  Amyotrophic lateral sclerosis
puc05020  Prion disease
puc05022  Pathways of neurodegeneration - multiple diseases
puc05132  Salmonella infection
puc05133  Pertussis
puc05135  Yersinia infection
puc05140  Leishmaniasis
puc05142  Chagas disease
puc05145  Toxoplasmosis
puc05152  Tuberculosis
puc05161  Hepatitis B
puc05163  Human cytomegalovirus infection
puc05167  Kaposi sarcoma-associated herpesvirus infection
puc05169  Epstein-Barr virus infection
puc05170  Human immunodeficiency virus 1 infection
puc05171  Coronavirus disease - COVID-19
puc05205  Proteoglycans in cancer
puc05208  Chemical carcinogenesis - reactive oxygen species
puc05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
puc05415  Diabetic cardiomyopathy
puc05417  Lipid and atherosclerosis
puc05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:puc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    125937868
   04015 Rap1 signaling pathway
    125937868
   04370 VEGF signaling pathway
    125937868
   04668 TNF signaling pathway
    125937868
   04068 FoxO signaling pathway
    125937868
   04071 Sphingolipid signaling pathway
    125937868
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    125937868
  09143 Cell growth and death
   04114 Oocyte meiosis
    125937868
   04218 Cellular senescence
    125937868
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    125937868
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    125937868
   04613 Neutrophil extracellular trap formation
    125937868
   04620 Toll-like receptor signaling pathway
    125937868
   04621 NOD-like receptor signaling pathway
    125937868
   04622 RIG-I-like receptor signaling pathway
    125937868
   04625 C-type lectin receptor signaling pathway
    125937868
   04660 T cell receptor signaling pathway
    125937868
   04658 Th1 and Th2 cell differentiation
    125937868
   04659 Th17 cell differentiation
    125937868
   04657 IL-17 signaling pathway
    125937868
   04664 Fc epsilon RI signaling pathway
    125937868
   04670 Leukocyte transendothelial migration
    125937868
  09152 Endocrine system
   04912 GnRH signaling pathway
    125937868
   04914 Progesterone-mediated oocyte maturation
    125937868
   04917 Prolactin signaling pathway
    125937868
   04926 Relaxin signaling pathway
    125937868
   04935 Growth hormone synthesis, secretion and action
    125937868
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    125937868
  09156 Nervous system
   04728 Dopaminergic synapse
    125937868
   04723 Retrograde endocannabinoid signaling
    125937868
   04722 Neurotrophin signaling pathway
    125937868
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    125937868
  09158 Development and regeneration
   04380 Osteoclast differentiation
    125937868
  09159 Environmental adaptation
   04714 Thermogenesis
    125937868
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    125937868
   05208 Chemical carcinogenesis - reactive oxygen species
    125937868
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    125937868
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    125937868
   05161 Hepatitis B
    125937868
   05171 Coronavirus disease - COVID-19
    125937868
   05163 Human cytomegalovirus infection
    125937868
   05167 Kaposi sarcoma-associated herpesvirus infection
    125937868
   05169 Epstein-Barr virus infection
    125937868
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    125937868
   05135 Yersinia infection
    125937868
   05133 Pertussis
    125937868
   05152 Tuberculosis
    125937868
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    125937868
   05140 Leishmaniasis
    125937868
   05142 Chagas disease
    125937868
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    125937868
   05020 Prion disease
    125937868
   05022 Pathways of neurodegeneration - multiple diseases
    125937868
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    125937868
   05418 Fluid shear stress and atherosclerosis
    125937868
   05415 Diabetic cardiomyopathy
    125937868
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    125937868
   04932 Non-alcoholic fatty liver disease
    125937868
   04933 AGE-RAGE signaling pathway in diabetic complications
    125937868
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    125937868
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:puc01001]
    125937868
Enzymes [BR:puc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     125937868
Protein kinases [BR:puc01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   125937868
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH NAD_binding_8
Other DBs
NCBI-GeneID: 125937868
NCBI-ProteinID: XP_049508721
LinkDB
Position
B2
AA seq 360 aa
MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
TPGADLLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA
QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
NT seq 1083 nt   +upstreamnt  +downstreamnt
atgtctcaggagaggcccacgttctaccggcaggagctgaacaagacaatctgggaggtg
ccggagcgttaccagaacctgtccccggtgggctccggtgcctatggctccgtgtgtgct
gcctttgacacaaaaactgggttacgtgtggcagtgaagaagctctccagaccgtttcag
tccatcattcatgccaaaaggacctacagagaactgcggttacttaaacatatgaaacat
gaaaatgtgattggtctgttggatgtttttacacctgcaaggtctctggaggaattcaat
gatgtgtatctggtgacccatctcatgggagcagatctgaacaacattgtgaaatgtcag
aagcttacggatgaccatgttcagttccttatctaccagattctccgaggtctcaagtat
atacattcagctgacataattcacagggacctgaagcctagtaatctagctgtgaatgaa
gactgtgagctgaagatcttggattttggactggctcgacatacagatgatgaaatgaca
ggctatgtggccactaggtggtacagggctcctgagatcatgctgaactggatgcattac
aaccagacagttgatatttggtcagtgggatgcataatggctgagctgttgactggaaga
acgttgtttcctggtacagaccatattgatcagttgaagctcattttaagactcgttgga
accccaggggctgatcttttgaagaaaatctcctcagagtctgcaagaaactacattcag
tctttgacccagatgccgaaaatgaactttgcaaatgtatttattggtgccaatcccttg
gcggtggacttgctggagaagatgcttgtactggactcagacaagagaatcacagcggcc
caagcacttgcacacgcctactttgcccagtaccatgatcctgatgatgaaccagtggcc
gatccttatgatcagtcctttgaaagcagggacctccttatagatgaatggaagagcctg
acctacgatgaagtcatcagctttgtgcccccaccccttgaccaagaagagatggaatcc
tga

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