Providencia vermicola: G3341_03100
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Entry
G3341_03100 CDS
T06449
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
pvc
Providencia vermicola
Pathway
pvc00260
Glycine, serine and threonine metabolism
pvc00261
Monobactam biosynthesis
pvc00270
Cysteine and methionine metabolism
pvc00300
Lysine biosynthesis
pvc01100
Metabolic pathways
pvc01110
Biosynthesis of secondary metabolites
pvc01120
Microbial metabolism in diverse environments
pvc01230
Biosynthesis of amino acids
Module
pvc_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
pvc_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
pvc_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
pvc_M00526
Lysine biosynthesis, DAP dehydrogenase pathway, aspartate => lysine
Brite
KEGG Orthology (KO) [BR:
pvc00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
G3341_03100 (thrA)
00270 Cysteine and methionine metabolism
G3341_03100 (thrA)
00300 Lysine biosynthesis
G3341_03100 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
G3341_03100 (thrA)
Enzymes [BR:
pvc01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
G3341_03100 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
G3341_03100 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
DUF2652
Motif
Other DBs
NCBI-ProteinID:
QIC14753
LinkDB
All DBs
Position
722673..725132
Genome browser
AA seq
819 aa
AA seq
DB search
MRVLKFGGTSVANDERVLNVADIAESKLADGPVALVLSAPAKITNHLVAMIDKTVAGQDV
ITHVNDAEMIFANLLKGLKEKQPGFDYDRLKKLTEQEFAQIKQVLHGITLLGQCPDSINA
SIICRGEKLSIAIMESVLKARGHKVTVINPVERLLAVGHYLESTVDINESTKRIAELNIP
KDHFVLMAGFTAGNDKGELVVLGRNGSDYSAAVLAACLRAACCEIWTDVDGVYTCDPRLV
PDARLLKGMSYQEAMELSYFGAKVLHPRTIAPIAQFQIPCLIKNTTNPSAPGTLIGDGQT
DESTPVKGITNLNNMAMINVSGPGMKGMVGMAARIFSVMSRKGISVVLITQSSSEYSISF
CVPQGELVRARAALEEEFYLELKDGVLDPLDVMEQLAIISVVGDGMRTLKGISARFFSAL
TRGNINIVAIAQGSSERSISAVIANEAATTAVRLCHQMLFNAEQVIEAFIIGVGGVGNAL
IEQIHRQQQWLKQKHIDLRVCGIANSRAMLTNMQGISLDNWKEELAQATEPFSLSRLIRL
EREYHFLNPVIIDCTSNQEIAEQYVNFLKDGFNVVTPNKKANTLSMDYYRQLRSACEVSK
RKFLYDTNVGAGLPVIENLQNLLNAGDELVHFSGILSGSLSFIFGKLDEGMSLSEATTLA
KEKGFTEPDPRDDLSGMDVARKLLILAREAGYQLELDDIEIDAVLPAEFDSSGSVAEFMA
RLPQLDQQFAERIKAAEAEEKVLRYVGLIEEGRCQVKIVAVDGNDPLFKVKNGENALAFY
TRYYQPIPLVLRGYGAGNDVTAAGVFADMLRTLSWKLGV
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgcgtgtgcttaaatttggcggtacttcggttgcaaatgacgaacgagtacttaatgtt
gctgacatcgctgagagtaaattggccgatgggccggtggctttggtgttatccgcacca
gcaaaaatcactaaccatttggtcgcaatgattgataaaacggttgcaggtcaggatgtc
atcacgcatgtgaatgatgcagaaatgatttttgcaaacttactaaaaggattgaaagaa
aaacaacccggttttgattacgacagactgaaaaaactcaccgaacaagaatttgcacaa
atcaaacaagtactgcatggtattactcttctaggccaatgccctgatagcattaatgct
tccatcatttgtcgtggtgaaaaactctccattgctatcatggaatctgtgttaaaagca
cgcggacacaaagtgacagtgattaaccctgtcgaacgtttattagcagttggccattac
cttgaatcaacagttgatatcaatgaatcgactaagcgtattgcagaattaaatatcccg
aaagaccactttgtattgatggcgggttttactgcgggtaatgataaaggcgaactggtg
gtattaggacgcaatggttctgattattctgccgctgttttagcagcttgtttacgggcg
gcctgttgtgagatctggaccgatgtggatggggtgtatacctgtgaccctcgtttagtg
cctgatgcgcgtttattaaaagggatgtcttaccaagaagcaatggaactgtcctacttt
ggtgcaaaagttcttcacccacgcaccatcgcgccaatcgcacaattccaaattccttgc
ctgattaaaaataccactaatccaagtgctccggggactttgattggcgatggtcaaacg
gatgaaagtacaccagttaaagggatcacgaatcttaataacatggcaatgatcaacgtt
tcgggtcctggcatgaaagggatggttggcatggcagctcgtattttctcagtcatgtcg
cgtaaagggatctcggtggtcttgattactcagtcatcatccgaatacagcattagtttc
tgtgtgccacaaggtgaattagtgcgagcacgcgcagcactggaagaagagttctattta
gaattaaaagacggtgtcttggatcctcttgatgtcatggagcagttggcgattatttcc
gtagtgggagatgggatgcgtacccttaaagggatatcagcacgtttcttttcagcttta
acacgcggaaatataaatattgttgcgattgcgcaaggttcatctgaacgctccatttca
gcggtcatcgcgaatgaggcggcaacaacggcagttcgtttatgccatcaaatgctattt
aatgcagagcaggtgatagaagcctttatcattggggtagggggggttggaaatgcattg
attgaacagatccatcgccaacaacaatggttaaagcaaaaacatattgatttacgtgtg
tgcggaattgctaactcaagagccatgctaaccaatatgcaaggcatctctcttgataat
tggaaagaagaacttgcacaagcgacagaaccctttagcttaagtcgtttgatcagactt
gaacgtgaatatcacttcctcaatcctgtgattatcgattgtacctctaaccaagagatt
gccgagcagtatgtgaatttcttaaaagatggttttaacgtggtcacgcctaataaaaaa
gccaacacgttatcgatggattattaccgccaactacgttcagcgtgtgaagtatcaaaa
cgtaagttcctttatgacactaacgttggtgcaggtttgccggtgattgaaaacttacag
aatcttctgaatgcgggtgatgagctggtgcactttagtggaattctctctggctcacta
tcctttatctttggtaagttagatgaaggtatgtctctgtctgaggcgacaacattagcg
aaagagaaaggatttactgagcctgacccacgtgatgacttatccggtatggatgttgct
cgtaaactgttgatccttgctcgtgaagcgggctatcaattagagctagacgatattgaa
attgatgcggtattacctgctgagtttgatagcagtggcagtgttgctgaatttatggct
cgtttaccacagctcgaccaacaatttgcagaacgtataaaagccgcagaagcggaagaa
aaagtgttacgctatgttgggttgatagaggaaggacgttgccaagtaaaaattgttgcc
gttgatggcaatgatccactctttaaagtcaagaatggcgaaaacgcattggctttctat
acacgctattaccaaccaatacctttagttctaagaggctatggtgcaggtaatgatgtt
accgctgccggcgtatttgcagatatgttgcgtaccctatcatggaaattgggagtctga
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