Prionailurus viverrinus (fishing cat): 125149914
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Entry
125149914 CDS
T09889
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
pviv
Prionailurus viverrinus (fishing cat)
Pathway
pviv00790
Folate biosynthesis
pviv01100
Metabolic pathways
pviv01240
Biosynthesis of cofactors
pviv01523
Antifolate resistance
pviv04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
pviv00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
125149914 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
125149914 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
125149914 (FPGS)
Enzymes [BR:
pviv01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
125149914 (FPGS)
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
125149914
NCBI-ProteinID:
XP_047685015
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Position
D4:complement(1286103..1295058)
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AA seq
593 aa
AA seq
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MSQARRHLRPALFLAAVSARVATTGVAARRGLSAWPAPQEPGMEYQDAVRALNTLQTNAG
YLEQVKRQRGDPQAQLEAMKLYLARSGLQVEDLDQLNIIHVTGTKGKGSTCAFTERILRS
YGLKTGFFSSPHLVQVRERIRINGQPISPELFTKHFWPLYHRLEETKDSSSYVSMPAYFR
FLTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPAVCGISSLGIDHTSILGDTVEEI
AWQKGGIFKRGVPAFTVLQPDGPLAVLRDRAQQISCPLYLCPPLEALEEGGPPLTLGLEG
EHQRSNAALALQLARCWLQQKDYRVPRSRPSPLPGSSGIGELKVSRPSLLRQMPLAPVFQ
PTTHMRHGLRDTEWLGRTQVLRRGPLTWYLDGAHTASSMQACVRWFRQALHRRQRPSRGS
EVLVLLFNSTGDRDPAALLKLLQPCQFDYAVFCPNLTEVSTVGNADQQNFMVTLDQVLLR
CLAHQQHWSRLDEEQAGPEPGEPTSSLLAPHPPEPRSTSSLVFSCISHALLWISQGRDPV
FHPPSPPQGLFAHPVAGSGAGVLREAAAIHVLVTGSLHLVGGVLKLLEPALSQ
NT seq
1782 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcaggcacgccgccacctgcgacccgctcttttcctggcggcggtttctgcgcgc
gttgcaactaccggggtagcggctcggcgagggttgagcgcgtggcccgcgccgcaggag
cccggcatggagtatcaggacgctgtgcgcgcactgaacaccctgcagaccaatgctggc
tatctggagcaggtaaagcgccagcggggtgaccctcaggcacagctggaagccatgaag
ctgtacttggcacggagtgggctgcaggtggaagacttggaccagctgaacatcattcac
gtcactgggaccaaggggaagggttccacttgtgcctttactgaacgtattctccgaagc
tatggcctgaagacaggattctttagctctccccacctggtgcaggtgcgggagcggatc
cgcatcaacgggcagcccataagccctgagctcttcaccaagcacttctggcccctctac
caccggctggaggagaccaaggacagcagcagctatgtctccatgcccgcctacttccgc
ttcctcacgctcatggccttccacgtcttcctccaagagaaggtggacctggcagtggtg
gaggtgggcattggtggcgcttacgactgcaccaacatcatcaggaagcctgcggtgtgt
ggcatctcctctcttggcatcgaccacaccagcattctgggggacacagtggaggagatc
gcgtggcagaaagggggcatcttcaagcgtggcgtccccgccttcaccgtgctccagcct
gacggtcccctggccgtgctgagggaccgggcccagcagatctcgtgtcctctctacctg
tgcccaccactggaagccctggaggaaggggggccgccgctgaccctgggcctggaggga
gagcaccagcggtccaatgccgccttggccttgcagctggctcgctgctggctacagcaa
aaggactaccgggtcccacgcagcaggccctcccccctccctggctcctcaggcatcggg
gagctgaaggtgtccaggcccagtctcttgcggcagatgcccctggcgcccgtgttccag
cccacgacccacatgcggcatgggcttcgggacacggagtggctgggccggacgcaggtg
ctgcggcgcgggcccctcacctggtacctggatggagcgcacaccgccagcagcatgcag
gcctgcgtgcgctggttccgccaggcgctgcaccgccgccagaggccaagccgcggctct
gaggtgcttgtcctgcttttcaactccactggagaccgggatcctgcagcactgctgaag
ctgctgcagccctgtcagtttgactatgctgttttctgccctaacctgacagaggtctca
actgttggcaatgcagaccagcagaacttcatggtgaccctggaccaggtgttgctccgc
tgccttgcacaccaacagcactggagccgcctggacgaggagcaggccggcccggagcct
ggtgagcccacatcctcgctgctggctccccacccgcccgagccccgtagcaccagctcc
ctcgtcttcagctgcatctcccacgccttgctgtggatcagtcaaggtcgggaccctgtc
ttccacccacccagtcccccgcagggcctcttcgcccaccctgtggcaggcagcggggcc
ggcgtgctccgtgaggctgccgccatccacgtgctggtcaccggcagcctgcacctggtg
ggcggcgtcctgaagctgctggagccggccctgtcccagtag
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