Prionailurus viverrinus (fishing cat): 125154173
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Entry
125154173 CDS
T09889
Symbol
NOS3
Name
(RefSeq) nitric oxide synthase, endothelial isoform X1
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
pviv
Prionailurus viverrinus (fishing cat)
Pathway
pviv00220
Arginine biosynthesis
pviv00330
Arginine and proline metabolism
pviv01100
Metabolic pathways
pviv04020
Calcium signaling pathway
pviv04022
cGMP-PKG signaling pathway
pviv04066
HIF-1 signaling pathway
pviv04071
Sphingolipid signaling pathway
pviv04151
PI3K-Akt signaling pathway
pviv04370
VEGF signaling pathway
pviv04371
Apelin signaling pathway
pviv04611
Platelet activation
pviv04915
Estrogen signaling pathway
pviv04921
Oxytocin signaling pathway
pviv04926
Relaxin signaling pathway
pviv04931
Insulin resistance
pviv04933
AGE-RAGE signaling pathway in diabetic complications
pviv05415
Diabetic cardiomyopathy
pviv05417
Lipid and atherosclerosis
pviv05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pviv00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
125154173 (NOS3)
00330 Arginine and proline metabolism
125154173 (NOS3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
125154173 (NOS3)
04371 Apelin signaling pathway
125154173 (NOS3)
04066 HIF-1 signaling pathway
125154173 (NOS3)
04020 Calcium signaling pathway
125154173 (NOS3)
04071 Sphingolipid signaling pathway
125154173 (NOS3)
04022 cGMP-PKG signaling pathway
125154173 (NOS3)
04151 PI3K-Akt signaling pathway
125154173 (NOS3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
125154173 (NOS3)
09152 Endocrine system
04915 Estrogen signaling pathway
125154173 (NOS3)
04921 Oxytocin signaling pathway
125154173 (NOS3)
04926 Relaxin signaling pathway
125154173 (NOS3)
09160 Human Diseases
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
125154173 (NOS3)
05418 Fluid shear stress and atherosclerosis
125154173 (NOS3)
05415 Diabetic cardiomyopathy
125154173 (NOS3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
125154173 (NOS3)
04933 AGE-RAGE signaling pathway in diabetic complications
125154173 (NOS3)
Enzymes [BR:
pviv01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
125154173 (NOS3)
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GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
Motif
Other DBs
NCBI-GeneID:
125154173
NCBI-ProteinID:
XP_047693940
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Position
A2:163631672..163649696
Genome browser
AA seq
1203 aa
AA seq
DB search
MGNLKSVGQEPGPPCGLGLGLGLGLCGKQGPASPTAEPGRAPAPAPPPPPAPDRSSPPLT
KPPEGPKFPRVKNWEVGSITYDTLSAQAQQEGPCTPRRCLGSLVFPRKLQSRPSQDPPPT
EQLLSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEIAAAGTYQLRESELVFGAKQAWRN
APRCVGRIQWGKLQVFDARDCNSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGD
FRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEPP
ELFALPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMST
EIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSYQLAKVTIVDH
HAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYVLSPAFHYQPDPW
KGSGSKGAGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGR
LFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSS
PRPEQHRSYKIRFNSVSCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHF
CAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQASCETFCVGEDAKAAA
RDIFSAKRSWKRQRYRLSTQAEGLQLLPGLIHVHRRKMFQATILSVENLQSSKSTRATIL
VRLDTGGQEGLQYQPGDHIGICPPNRPGLVEALLSRVEDPPPPGEPVAVEQLEKGSPGGP
PPSWVRDPRLPPCTLRQALTFFLDITSPPSPQLLRLLSTLAEESGEQQELESLSQDPRRY
EEWKWFRCPTLLEALEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSAHPGEIHLTVAVL
AYRTQDGLGPLHYGVCSTWLSQLKAGDPVPCFIRGAPSFRLPPDPSLPCILVGPGTGIAP
FRGFWQERLHDIDSKGLHPAPMTLVFGCRCSQLDHLYRDEVQDAQQRGVFGRVLTAFSRE
PDCPKTYVQDILRTELAAEVHRVLCLERGHMFVCGDVTMATSVLQTVQRILATEGDMELD
EAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERHLRGAVPWAFDPPGPDT
PSP
NT seq
3612 nt
NT seq
+upstream
nt +downstream
nt
atgggcaatttgaagagtgtgggccaggagccggggcctccctgcggcctggggctgggg
ctgggcctgggcctgtgcggcaagcagggcccagcctccccaacagcagagcccggcagg
gcaccggcacccgcacccccacccccacccgcgccagaccgcagcagtcctccgctcacc
aagcccccggaggggcccaagttccctcgtgtgaagaactgggaggtggggagcatcact
tacgacaccctgagtgcccaggcacagcaggaggggccctgcacccctagacgctgcctg
ggctccctggtttttccacggaaactgcagagccggccctcccaggacccaccacccact
gagcagctgctgagccaggccagggacttcatcaaccagtactacagctccatcaagagg
agtggctcccaggcccatgagcagaggcttcaggaggtggaagccgagatagcagccgca
ggcacataccagcttcgggagagcgagctggtgttcggggctaagcaggcttggagaaat
gcaccccgctgcgtgggccggatccagtgggggaagctgcaggtgtttgatgcccgggat
tgcaactctgcccaggagatgttcacctacatctgcaaccacatcaagtacgccaccaac
cggggcaacctccgctcggccatcacagtgttcccccagcgcgccccaggccgcggagac
ttccgaatctggaacagccaactggtgcgctacgcggggtacaggcagcaggatggctcc
gtgcggggggacccagccaacgtggagatcactgagctctgcatccagcacggctggacc
ccaggaaatggccgctttgacgtactgcccctactgctccaggccccagatgagcccccg
gaactctttgccctgccccccgagctggtcctcgaggtgcccctggagcaccccacgctg
gagtggtttgcggccctgggcctgcgctggtacgccctcccggcggtgagcaacatgctg
ctggaaattggggggctggagttccccgcggcccctttcagcggctggtacatgagcact
gagatcggcacgcggaacctgtgtgacccgcaccgatacaacatcctggaggatgtggcc
gtctgcatggacttggatacccggaccacctcatccctgtggaaagacaaggcagccgtg
gaaatcaacttggccgtgctgcacagttaccagctggccaaagtgaccattgtggaccac
catgctgccacggcctccttcatgaagcacctggagaatgagcagaaggctagggggggc
tgccctgccgactgggcctggatcgtgccccccatctccggcagcctcacccctgtgttc
catcaggagatggtcaactatgtcctgtcccctgccttccactatcagccagacccgtgg
aagggaagtgggtccaagggtgccggcatcaccaggaagaagacctttaaggaagtggcc
aatgcggtgaagatctctgcctcactcatgggcaccgtgatggcaaagcgagtaaaggca
acaatcctgtatggctccgagaccggccgggcccagagctatgcacagcagctggggaga
ctcttccggaaggctttcgatccccgggtcctgtgcatggatgagtatgatgtcgtgtcc
ctcgagcatgagacgctagtgctggtcgtgaccagcacattcgggaatggtgatccccca
gagaatggagagagttttgcggcggccctgatggaaatgtctggtccctacaacagctcc
cctcggccagaacaacacaggagttacaaaatccgcttcaacagtgtctcctgctcagac
ccgctggtgtcctcctggaggcggaagagaaaggagtccagtaacacagacagtgcaggg
gcactgggtaccctcaggttctgtgtgttcgggctgggctcccgggcgtacccccacttc
tgtgcctttgcccgtgcggtggacacgcggctggaggagctgggtggcgagcggctgctg
cagctgggccagggagatgagctgtgtggccaggaggaggccttccgtggctgggcccag
gccgccttccaggcctcctgtgagactttctgcgtgggagaggacgccaaggctgccgcc
agggacatattcagcgccaaacggagctggaagcgccaaaggtaccggctcagcacccag
gcggagggcctccagctgctgccaggcctgatccatgtgcacaggaggaagatgttccag
gctaccatcctctcagtcgaaaacctgcaaagcagcaagtccacccgggccacgatcctg
gtgcgcctggacactggaggccaggaggggctgcagtaccagccgggggaccacataggc
atctgcccgcccaaccgaccgggcctcgtggaggcgctgctgagccgtgtggaggacccg
cctccgccaggagagcctgtggccgtggagcagctggagaagggcagccctggtggccca
ccccccagctgggttcgggacccccggctgcccccctgcacgctgcgccaggctctcacc
ttcttcctggacatcacctccccgcccagccctcaactccttcgactgctcagcaccctg
gcggaagagtccggagaacagcaggagctggagagcctcagccaggacccccggcgctac
gaggaatggaagtggttccggtgccccacgctgctggaggcgctggaacagttcccgtcc
gtggcgctgcctgcccccctgctcctcacccagctgcccctgctccagccccggtactac
tccgtcagctcggcgcccagcgcccacccgggagagattcacctcacagtggccgtgctg
gcgtacaggacccaggatggactgggccccctgcactatggagtctgctccacatggctg
agccagctgaaggccggagatcctgtaccttgcttcatcaggggggctccctccttccgg
ctgccgcctgatcccagcttgccctgcatcctagtgggccctggcacaggtattgccccc
ttccggggattttggcaggagcggctgcacgacattgacagcaaagggctgcacccggcc
cccatgaccttggtgttcggctgccgatgctcccagctcgaccacctctaccgcgacgag
gtgcaggatgcccagcagcgcggggtttttggacgcgtcctcaccgccttctctcgggag
cccgactgccctaagacctacgtgcaggacatcctgcggacggagctggcggctgaggtg
caccgcgtgctgtgcctcgagcggggccacatgtttgtgtgcggcgacgtcaccatggca
accagcgtcctgcagacggtgcagcgaatcctagcgacggagggcgacatggagctggac
gaggccggcgacgtcatcggcgtgctgcgggatcagcaacgctatcacgaggacattttc
gggctcacactgcgcacccaggaggtgactagccgcatacgcacccagagcttttccctg
caggagcggcatctgcgcggcgcagtgccctgggcgttcgaccctcccggcccagacacc
cccagtccctga
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