Prionailurus viverrinus (fishing cat): 125154230 Help Entry 125154230         CDS       T09889                                  Symbol TSC2 Name (RefSeq) tuberin isoform X1   KO K07207   tuberous sclerosis 2 Organism pviv  Prionailurus viverrinus (fishing cat) Pathway pviv04072   Phospholipase D signaling pathway pviv04115   p53 signaling pathway pviv04140   Autophagy - animal pviv04150   mTOR signaling pathway pviv04151   PI3K-Akt signaling pathway pviv04152   AMPK signaling pathway pviv04211   Longevity regulating pathway pviv04218   Cellular senescence pviv04714   Thermogenesis pviv04910   Insulin signaling pathway pviv04919   Thyroid hormone signaling pathway pviv05163   Human cytomegalovirus infection pviv05165   Human papillomavirus infection pviv05168   Herpes simplex virus 1 infection pviv05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:pviv00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     125154230 (TSC2)    04151 PI3K-Akt signaling pathway     125154230 (TSC2)    04152 AMPK signaling pathway     125154230 (TSC2)    04150 mTOR signaling pathway     125154230 (TSC2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     125154230 (TSC2)   09143 Cell growth and death    04115 p53 signaling pathway     125154230 (TSC2)    04218 Cellular senescence     125154230 (TSC2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     125154230 (TSC2)    04919 Thyroid hormone signaling pathway     125154230 (TSC2)   09149 Aging    04211 Longevity regulating pathway     125154230 (TSC2)   09159 Environmental adaptation    04714 Thermogenesis     125154230 (TSC2)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     125154230 (TSC2)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     125154230 (TSC2)    05163 Human cytomegalovirus infection     125154230 (TSC2)    05165 Human papillomavirus infection     125154230 (TSC2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:pviv01009]     125154230 (TSC2) Protein phosphatases and associated proteins [BR:pviv01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      125154230 (TSC2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP HEAT Cnd1 Motif Other DBs NCBI-GeneID:  125154230 NCBI-ProteinID:  XP_047694074 LinkDB All DBs Position E3:complement(40227313..40262353) Genome browser AA seq 1809 aa AA seqDB search MAKPTSKDSGLKEKFRILFGLGTPRPNPRSAEGKQTEFIITAEILRELSVECGLNNRIRV IGQICEVAKTKKFEEHAVEALWKAVEDMLQPERPPEARHAVLALLKAIVQGQGDRLGVLR ALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELAGFVLQWMDIGLSSEFLLVL VNLVKFNSCYLDEYIASMVHMICLLCVQTVSSVDIEVSLQVLDAVVCYNCLPAESLPLFI VTLCRTVNVKELCEPCWKLMRNLLGTHLGHSAIYNMCRIMEDRAYMEDAPLLRGAVFFVG MALWGAHRLYSLKNSPTSVLPSFYEAMTCPNEVVSYEIVLSVTRLIKKYRRELQAVTWDI LLDIIERLLQQLQSLDSPELRAIVHDLLTTVEELCDQNEFHGSHERYFELVERCADQRPE SSLLNLITYRAQSIHPAKDGWIHNLQLLMERFFRNESRSAVRIKVLDVLSFVLLINRQFY EEELISSVVISQLSHIPEDKDPQVRKLATQLLVDLAEGCHTHHFNSLLDIVEKVMARSLS APPELEERDVVAYSASLEDVKTAVLGLLVILQTKLYALPASHAVRVYETLVSHLQLHYKH GYTLPIASSIRLQAFDFLLLLRADSLHRLGLPSKDGAVRFSPYCVCDSTEPERGSEKKAG GPLSPPTGPSGPAPAGPAVRLGSLPYSLLFRVLLQCLKQETDWKVLKLVLGKLPESLRFK VLIFTSPCSVDQLSSALCSMLSGPRTLERLRGTPEGFSRTDLHLAVVPVLTALISYHNYL DKARQREMVYCLEQGLIYRCASQCVVALAVCSVEMPDIIIKALPVLVVKLTHISATASMA IPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC RLPFRKDFVPYITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARPPKQGLNNS PPVREFQESSAADAFRCRSISVSEHVVRSRIQTSLTSASLGSADENSMAQADDNLKNLHL ELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSL LGLDSGELRGSPELSSDPSAHVRQTKEAPAKLESQAGQQVCRGARDRVRSMSGGHGLRVG ALDAPATHCPGAQTTPASTSERASAAAQLPAQEKTSLAAYVPLLTQGWAEILVRRPTGNT SWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKERRDTALYKSLSVPAAGSAKPPPP PRSNTVASFSSLYQTSCQGELHRSISWADSAVVLEEGSPSETDLPGEPTELEDFEATLGP ERRCRRPEAYSRSSSSSSQEEKSFAAEEVAAGGLPIGRAVSAEGARPSAGLSFQPAQPLS KSSSSPELQTLQDTLGDPGDKADVGRLSPEAKARSQSGTLDGAGATWSTPGEESQGRGPA RPEGPLPSGCPRSPGGLRPRGYTISDSAPSRRGKRVERDAFKSRAGASNTEKVPGINPSF VFLQLYHSPFFGDESNKPILLPNESFERSVQLLDQIPSYDTHKIAVLYVGEGQSSSELAI LSNEHGSYRYTEFLTGLGKLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHI ATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIITPLDYECN LVSLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWI ARLRHIKRLRHRVGQIREEAHYSNPSLPLTQTHPPGHAKAPAPAEPMPTYETGQRKRLIS SVDDFTEFV NT seq 5430 nt NT seq  +upstreamnt  +downstreamnt atggccaagccgacaagcaaggattcaggcttgaaggagaagttcaggattctgtttgga ctgggaaccccgcggccaaaccccaggtctgcagagggcaagcagacggagtttatcatc acggcggaaatcctgagagagctgagcgttgaatgtggcctcaacaatcgcatccgggtg atagggcagatctgtgaagttgcaaaaacgaagaagtttgaagagcatgcagtggaagcg ctctggaaggccgtcgaggacatgctgcagccagagcggccaccggaggcccggcatgcg gtgctggctctgctgaaggccatcgtgcaggggcagggggaccgcttgggcgttctcagg gccctcttctttaaggtcatcaaggattacccctctaatgaagatctccacgaaagactg gaagttttcaaggccctcacagacaatgggagacacatcacatatttggaagaagaactg gctgggtttgtgctgcagtggatggacatcggcctgtcctcagagttccttctggtgctt gtgaacttggtcaaattcaacagctgttacctggatgaatacatcgcatcaatggtccac atgatctgcctgctgtgcgtccagactgtgtcctccgtggacatagaggtctctctgcag gtgctggacgccgtcgtctgctacaactgtctgccggctgagagcctgcccctgttcatc gtcactctctgtcgtaccgtcaacgtcaaggagctctgtgagccttgctggaagctgatg cgtaatcttctgggcacccacctgggtcacagtgccatctacaacatgtgccgcatcatg gaggacagagcctacatggaagacgccccgctgctgagaggggccgtgttctttgtgggc atggctctctggggggcgcaccgactctactcgctcaagaactccccgacatccgtgctg ccgtcgttttatgaggccatgacctgtccgaacgaggtggtgtcctatgaaatcgtcctg tctgtcaccagactcatcaagaagtaccggagggagctccaggctgtgacgtgggatatc ctcctggacatcatcgaacgtctgctgcagcagctccagagcctggacagcccggagctc agagccatcgtccatgacctgctgaccacagtggaggagctgtgtgaccagaatgagttc cacggctcacacgagagatacttcgagctcgtcgagagatgtgcagaccagaggccggag tcctccctcctaaacttaataacctacagggctcagtccatccatccggcaaaggacggc tggattcacaacctgcagttactgatggagagattcttccggaatgaatcccgcagtgct gtgcgcatcaaggtgctcgacgtcttgtcctttgtgctgctcatcaacaggcagttctat gaggaggagctgatcagctcggtggtcatctctcagctctcccacatcccggaggacaaa gacccccaagtccggaaactggccacccagttgctggtggacctggccgaaggctgtcac acccaccacttcaacagcctgctggacattgtggagaaggtgatggcccgctccctttcc gcaccccctgagctggaggaaagagatgtggtggcatattcagcctccttagaggatgtg aagactgccgtcttggggctcctggtgatccttcagaccaagctgtacgccttgcctgcc agccacgcggtgcgtgtgtacgagaccctcgtcagccacctgcagctccactacaagcac ggctataccctgcccatcgccagtagcatccggctgcaggcctttgacttcctgctgctg ctgagggcggactccctgcaccgcctcggcctgcccagcaaggacggggctgtgaggttc agcccctactgcgtctgcgactccacggagccagagagaggctctgagaagaaggccggc ggccccctgtcgcctcccaccgggccgtccggcccagcacctgccggtcccgctgtgcgg cttggctccctgccctactccctgctcttccgggtcctgctgcagtgcttaaagcaggag acggactggaaggtgctgaagcttgttctcggcaagctgcccgagtccctgcgcttcaag gtcctcatcttcacgtccccgtgcagcgtcgaccagctgtcttccgccctctgctccatg ctttcaggtcccagaactctggagcggctccgaggcaccccggaaggtttctccaggacc gacctgcacctggctgtggttcctgtgctgacggcgttaatctcttaccataactatttg gacaaagccagacagcgggagatggtgtactgcctggagcaaggcctgatctaccgctgt gccagccagtgtgtggtggccctggccgtgtgcagcgtcgaaatgcccgacatcatcatc aaggcgctgcctgtcttggtcgtgaagctcacacacatttcggccacagccagcatggcc attccactcctcgaattcctgtcaactctggccaggctgcctcacctctacaggaacttt gccgctgagcagtacgcgagtgtgtttgccatctccctgccgtacaccaacccctccaag tttaatcagtacatcgtgtgcctggcccatcacgtcatagccatgtggttcattagatgt cgtctgccttttcggaaggattttgttccttatatcactaagggcctacgctccaatgtc ctcctgtcttttgatgacaccccggagaaggacagcttcagagcgcggagcaccagtctc aacgagaggcccaagagtttgaggatagccagaccccccaaacaaggcttgaataactcc ccacccgtgagagaattccaggagagctctgcagccgacgccttccggtgccgcagcatc agtgtgtctgaacatgtggtccgcagcaggatccagacgtccctcacgagtgccagcttg gggtctgcggacgagaactcaatggcccaggctgacgacaacttgaaaaatctccacctg gagctcacggagacttgtctggacatgatggccagatacgtgttctccaacttcacggcg gtccccaagaggtcccctgtaggggagttcctcttggctggtggcaggaccaagacctgg ctggttggaaacaagctcgtcaccgtgacgacgagcgtggggaccgggacccggtcactg ctgggcttggactcaggagagctgcggggcagcccagagctgagctctgaccccagtgcg catgtgaggcagacaaaggaggcgcctgccaagttggagtcccaggctgggcagcaggtg tgccgtggggcccgggaccgcgtccgctccatgtctgggggccacggccttcgtgttggt gccttggacgctcccgccacccactgcccaggcgcacagaccacaccggccagcacgtct gagagggcctcggctgccgcccagctcccggcgcaggagaagacgagcctggcggcctac gtacccctgctgacccagggctgggcggagatcttggtccggaggcccacggggaacacc agctggctgatgagcctggagaaccccctcagccccttctcctcggacatcaacaacatg cccctgcaggagctgtccaacgccctcatggccgccgaacgcttcaaggagcgtcgtgac acggccctgtacaagtcactttcggtgccggcggccggctccgccaagccccctccgccc ccacgttctaacacagtggcctctttctcctccctgtaccagaccagttgccaaggagag ctgcacaggagcatttcctgggcagactccgcggtggttctggaggagggaagtcccagc gagactgatttgccaggcgagcccactgagctggaggactttgaggccaccctgggccca gagaggcgctgtcggcgccctgaagcctacagtagatcgtcttccagctccagccaagag gagaagtctttcgccgcagaggaggtggctgccggagggctccccatcgggcgggccgtg tctgccgagggagcccggccctctgcggggctctccttccagcccgcccagcccctcagc aagtctagctcctcgccggagctgcagaccctgcaggatacactcggggaccctggggac aaggccgacgttggccggctgagccccgaggccaaggcccgctcacagtccgggactctg gacggggcaggtgccacctggtcaaccccaggtgaagagagtcagggccggggccctgcg aggcccgagggtcccttgccttctggctgtccccgttcccccggtggcctgcgtcccaga ggctacaccatttcggattcagccccgtcacgcagaggcaagagggtagagcgggacgcc ttcaagagcagagctggggcctccaatactgagaaggtgccgggcatcaaccccagcttc gtgttcctgcagctctaccactctcctttctttggcgacgagtccaacaagccgatcctt ctgcctaacgagtccttcgagcggtcggtgcagctcctcgaccagatcccatcctatgac acgcacaagatcgcggtcctgtacgtgggagaaggccagagcagcagcgagctcgccatc ctgtccaacgagcacggctcgtaccggtacacagagttcctgacgggcctgggcaagctc atcgagctcaaggactgccagccggataaggtgtacctgggcggtctggacgtgtgcggg gaggacggccagttcacctactgctggcacgatgacatcatgcaggctgtcttccatatc gccaccctgatgcccaccaaggacgtggacaagcaccgctgtgacaagaagcgccatctg ggcaacgactttgtgtccattgtctataatgactccggcgaggacttcaaactgggcacc attaaaggccagttcaacttcgtccacgtgatcatcacccccctggactacgagtgcaac ctggtgtccctgcagtgcaggaaggacatggagggcctcgtggacaccagcgtggccaag atcgtgtctgatcgcaacctgcccttcgtggcccgtcagatggctctgcacgccaacatg gcctcccaggtgcaccatagccgctccaaccccacggatatctacccgtccaagtggatc gccaggctccgtcacatcaagcggctgcgccaccgggtagggcagatccgtgaggaagcc cactactccaacccgagcctgccgctgacgcagacgcaccctccgggccacgccaaggcc ccggccccggccgagcccatgcccacgtacgagacgggccagcggaagcgcctcatctcc tctgtggatgacttcaccgagttcgtgtga

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