KEGG   Prionailurus viverrinus (fishing cat): 125161813
Entry
125161813         CDS       T09889                                 
Symbol
GNAS
Name
(RefSeq) guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas isoform X1
  KO
K04632  guanine nucleotide-binding protein G(s) subunit alpha
Organism
pviv  Prionailurus viverrinus (fishing cat)
Pathway
pviv01522  Endocrine resistance
pviv04015  Rap1 signaling pathway
pviv04020  Calcium signaling pathway
pviv04024  cAMP signaling pathway
pviv04072  Phospholipase D signaling pathway
pviv04081  Hormone signaling
pviv04082  Neuroactive ligand signaling
pviv04261  Adrenergic signaling in cardiomyocytes
pviv04270  Vascular smooth muscle contraction
pviv04540  Gap junction
pviv04611  Platelet activation
pviv04713  Circadian entrainment
pviv04714  Thermogenesis
pviv04724  Glutamatergic synapse
pviv04726  Serotonergic synapse
pviv04728  Dopaminergic synapse
pviv04730  Long-term depression
pviv04750  Inflammatory mediator regulation of TRP channels
pviv04911  Insulin secretion
pviv04912  GnRH signaling pathway
pviv04913  Ovarian steroidogenesis
pviv04915  Estrogen signaling pathway
pviv04916  Melanogenesis
pviv04918  Thyroid hormone synthesis
pviv04921  Oxytocin signaling pathway
pviv04922  Glucagon signaling pathway
pviv04923  Regulation of lipolysis in adipocytes
pviv04924  Renin secretion
pviv04925  Aldosterone synthesis and secretion
pviv04926  Relaxin signaling pathway
pviv04927  Cortisol synthesis and secretion
pviv04928  Parathyroid hormone synthesis, secretion and action
pviv04934  Cushing syndrome
pviv04935  Growth hormone synthesis, secretion and action
pviv04961  Endocrine and other factor-regulated calcium reabsorption
pviv04962  Vasopressin-regulated water reabsorption
pviv04970  Salivary secretion
pviv04971  Gastric acid secretion
pviv04972  Pancreatic secretion
pviv04976  Bile secretion
pviv05012  Parkinson disease
pviv05030  Cocaine addiction
pviv05031  Amphetamine addiction
pviv05032  Morphine addiction
pviv05034  Alcoholism
pviv05142  Chagas disease
pviv05146  Amoebiasis
pviv05163  Human cytomegalovirus infection
pviv05165  Human papillomavirus infection
pviv05200  Pathways in cancer
pviv05207  Chemical carcinogenesis - receptor activation
pviv05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:pviv00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    125161813 (GNAS)
   04020 Calcium signaling pathway
    125161813 (GNAS)
   04072 Phospholipase D signaling pathway
    125161813 (GNAS)
   04024 cAMP signaling pathway
    125161813 (GNAS)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    125161813 (GNAS)
   04081 Hormone signaling
    125161813 (GNAS)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    125161813 (GNAS)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    125161813 (GNAS)
  09152 Endocrine system
   04911 Insulin secretion
    125161813 (GNAS)
   04922 Glucagon signaling pathway
    125161813 (GNAS)
   04923 Regulation of lipolysis in adipocytes
    125161813 (GNAS)
   04912 GnRH signaling pathway
    125161813 (GNAS)
   04913 Ovarian steroidogenesis
    125161813 (GNAS)
   04915 Estrogen signaling pathway
    125161813 (GNAS)
   04921 Oxytocin signaling pathway
    125161813 (GNAS)
   04926 Relaxin signaling pathway
    125161813 (GNAS)
   04935 Growth hormone synthesis, secretion and action
    125161813 (GNAS)
   04918 Thyroid hormone synthesis
    125161813 (GNAS)
   04928 Parathyroid hormone synthesis, secretion and action
    125161813 (GNAS)
   04916 Melanogenesis
    125161813 (GNAS)
   04924 Renin secretion
    125161813 (GNAS)
   04925 Aldosterone synthesis and secretion
    125161813 (GNAS)
   04927 Cortisol synthesis and secretion
    125161813 (GNAS)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    125161813 (GNAS)
   04270 Vascular smooth muscle contraction
    125161813 (GNAS)
  09154 Digestive system
   04970 Salivary secretion
    125161813 (GNAS)
   04971 Gastric acid secretion
    125161813 (GNAS)
   04972 Pancreatic secretion
    125161813 (GNAS)
   04976 Bile secretion
    125161813 (GNAS)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    125161813 (GNAS)
   04961 Endocrine and other factor-regulated calcium reabsorption
    125161813 (GNAS)
  09156 Nervous system
   04724 Glutamatergic synapse
    125161813 (GNAS)
   04728 Dopaminergic synapse
    125161813 (GNAS)
   04726 Serotonergic synapse
    125161813 (GNAS)
   04730 Long-term depression
    125161813 (GNAS)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    125161813 (GNAS)
  09159 Environmental adaptation
   04713 Circadian entrainment
    125161813 (GNAS)
   04714 Thermogenesis
    125161813 (GNAS)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    125161813 (GNAS)
   05207 Chemical carcinogenesis - receptor activation
    125161813 (GNAS)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    125161813 (GNAS)
   05165 Human papillomavirus infection
    125161813 (GNAS)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    125161813 (GNAS)
   05142 Chagas disease
    125161813 (GNAS)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    125161813 (GNAS)
  09165 Substance dependence
   05030 Cocaine addiction
    125161813 (GNAS)
   05031 Amphetamine addiction
    125161813 (GNAS)
   05032 Morphine addiction
    125161813 (GNAS)
   05034 Alcoholism
    125161813 (GNAS)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    125161813 (GNAS)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    125161813 (GNAS)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    125161813 (GNAS)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:pviv04147]
    125161813 (GNAS)
   04031 GTP-binding proteins [BR:pviv04031]
    125161813 (GNAS)
Exosome [BR:pviv04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   125161813 (GNAS)
  Exosomal proteins of other body fluids (saliva and urine)
   125161813 (GNAS)
  Exosomal proteins of colorectal cancer cells
   125161813 (GNAS)
  Exosomal proteins of bladder cancer cells
   125161813 (GNAS)
GTP-binding proteins [BR:pviv04031]
 Heterotrimeric G-proteins
  Alpha Subunits
   Alpha type 2 (Gs)
    125161813 (GNAS)
SSDB
Motif
Pfam: G-alpha Arf Gtr1_RagA GTP_EFTU
Other DBs
NCBI-GeneID: 125161813
NCBI-ProteinID: XP_047707886
LinkDB
Position
A3:complement(4455756..4510498)
AA seq 1004 aa
MGVRNCLDGNNMSGQRDIPLELGEQPEQPPLEAPGAAAPSPGPGAAEEMETEPPHSEPVP
LEIEGEACGPPEVSGPNCQDLGQAIEETRALGGYSPPPEEAMPFEVEQPSPGGFWPTLEQ
PGDTTGAQAGPEVFSPTVMEPGAFDDARPRLGGYSPPPEEAMPFEFEQPAQGGCSQPLLQ
VSDLAPGGPGAGVFSTPPQEPGALKPATTGFRGDCSPPPEEAMPFEFDGAAFGDDSPPPG
LPRAIPQIDGGSIGQPAAVAVPSAVLLAPAANEPPLWVPGAIGSPSREAVRSPPHFAGDS
PPMEISGPPLEIGSAPVGVDDAPVNMDSPPIALDGPPIEVSGAPVKRERAEGERPPVEGE
AAEMEGGSAAASAAGRGEVPSPGDGAPAAGAAPASPAAPAAPAAGAAAAAPAAPAAGAAA
PAARAAPAAPAAPAAGAAPAARAAPAAPASGARPKLRFLRPPSPEIQAADPPTPQPTRAF
AWRGRSGRGRDDDERSVSSDDDHSSDESDDGTSGCRRWLQPRRNRRRRKPRRNLLRKFLM
QAFGGCFGRSESPQPKAAPSPKVKKIPLAEKRRQMRKEALEKRAQKRAEKKRSQLIDKQL
QEEKMGYMCTHRLLLLGRKVVPSNTEGRFRLDKPAPATVRCPRVLGWGPARKAGASGAGE
SGKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAM
SNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQ
LIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDE
RRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILF
LNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRIST
ASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL
NT seq 3015 nt   +upstreamnt  +downstreamnt
atgggcgtgcgcaactgcctcgacggcaataatatgtcaggacaacgcgatatccccctt
gaactcggggaacagcccgagcaaccacctttggaggccccaggggcagctgcccccagt
cctgggcctggcgcagccgaagagatggagaccgaaccgcctcacagcgagcccgtcccc
ctcgagattgaaggcgaggcctgtggaccccccgaggtctccggacccaactgccaggac
ctgggccaggccatcgaggaaaccagagccctcggaggctacagcccacctcctgaggaa
gccatgcccttcgaggtcgagcagcccagcccaggaggcttctggcctaccctggagcag
cccggagacaccactggggcccaggcaggccctgaggtcttcagcccaacggtcatggag
cccggagccttcgatgatgccagaccccgcctgggaggctacagccctccacctgaagaa
gccatgccctttgagtttgagcagcctgcacagggaggttgcagccagcctctcctgcag
gtctcagacctcgctccaggaggcccaggtgcaggggtcttcagcactcctccccaggag
cccggagccctcaagcctgcaaccacaggcttcagaggagactgtagtcctccccctgag
gaggctatgccatttgagtttgatggagcagcctttggggacgacagcccaccccccggg
ctcccccgagctatcccacaaatcgacggcggcagcatcggccagcccgcggcagtcgcg
gtcccgagtgcggtcctcctcgctcccgccgcgaacgagccccccctctgggtccccggc
gccatcggcagcccatcccgagaggctgtcagatctcctccacacttcgcgggcgacagc
cccccgatggagatctccggacccccgctcgagattggcagcgcccccgttggggtcgac
gacgctcccgtcaacatggacagccccccaatcgcgcttgacggcccgcccatcgaggtc
tccggagccccagttaagagagagcgagcagagggagagagacccccagttgagggagaa
gcagccgagatggaaggaggctcagccgccgcctctgctgcggggagaggagaagtcccc
tctcccggggacggagccccagcggccggggccgcccctgcctctccagccgcccctgcc
gctccggccgccggggcagccgctgccgcccctgccgctccggccgccggggcagcagct
ccggccgccagggcagctcctgccgcccctgccgctccggccgccggggcagctcctgcc
gcccgggcagcccctgccgcccctgcgtctggagcccgacccaagctccgcttcctccga
ccccccagccccgagatccaggctgccgatccacctactccgcagcctactcgcgcattt
gcctggcggggcaggtctggccgcggccgcgacgacgacgagaggtcggtcagcagcgac
gacgaccacagcagcgatgaatccgacgatgggacctccggatgccgccgctggctgcag
ccccggcgaaatcgccgccgccgaaagccccggcgcaacttgctccgcaagttcctcatg
caggccttcgggggctgcttcggccgatccgagagcccccagcccaaagccgcccccagc
cccaaggtcaagaagattcccctggcagagaagcgcagacagatgcgcaaggaagccctg
gagaagcgcgcccagaagcgcgcagagaagaaacgcagccagctcatcgacaaacaactc
caggaagaaaagatggggtacatgtgtacgcaccgcctgctgcttctagggagaaaagtg
gtgccgagcaacactgagggtcgtttccggctggacaagccagcgccagcgaccgtaaga
tgcccccgagtcctggggtgggggccggcaaggaaggcgggggcttcaggtgctggagaa
tctggtaaaagcaccattgtgaagcaaatgaggattctgcatgttaatgggtttaatgga
gagggcggcgaagaggacccgcaggctgccaggagcaacagcgatggtgagaaggcaacc
aaagtgcaggacatcaaaaacaacctgaaagaggccatcgaaaccatcgtggccgccatg
agcaacctggtcccccccgtggagctggccaaccccgagaaccagttcagagtggactac
attctgagcgtgatgaacgtgcccgactttgatttccctcccgagttctatgagcacgcc
aaggctctgtgggaggacgaaggagtgcgtgcctgctatgagcgctccaacgagtaccag
ctgattgactgcgcccagtacttcctggacaagatcgatgtcatcaagcaggctgactac
gtgcccagtgaccaggatctgcttcgctgccgcgtcctgacttctggaatctttgagacc
aagttccaggtggacaaagtcaacttccacatgttcgacgtgggtggccagcgtgacgag
cgccgcaagtggatccagtgcttcaacgatgtgactgccattatcttcgtggtggccagc
agcagctacaacatggtcattcgggaggacaatcagaccaaccgcctgcaggaggctctg
aacctcttcaagagcatctggaacaacagatggctgcgaaccatctccgtgatcctgttc
ctcaacaagcaagacctgctcgctgagaaagtcctcgctggaaaatcgaaaattgaggac
tactttccagaatttgctcgctacactactcccgaggatgctactcccgagcccggagag
gacccacgcgtgacccgggccaagtacttcatccgcgacgaatttctgagaatcagcact
gccagtggagacgggcgtcactactgctatccccacttcacttgcgccgtggacaccgag
aacatccgccgtgtgttcaacgactgccgtgacatcattcagcgcatgcaccttcgtcag
tacgagctgctctaa

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