Prionailurus viverrinus (fishing cat): 125166384 Help Entry 125166384         CDS       T09889                                  Symbol SYNE1 Name (RefSeq) nesprin-1 isoform X1   KO K19326   nesprin-1 Organism pviv  Prionailurus viverrinus (fishing cat) Pathway pviv04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:pviv00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     125166384 (SYNE1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:pviv03036]     125166384 (SYNE1) Chromosome and associated proteins [BR:pviv03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     125166384 (SYNE1) SSDB OrthologParalogGFIT Motif Pfam:  Spectrin Spectrin_SYNE1 CH SYNE1 KASH Spectrin_SYNE1_2 SR_desmoplakin_3 SYNE3 Motif Other DBs NCBI-GeneID:  125166384 NCBI-ProteinID:  XP_047716253 LinkDB All DBs Position B2:complement(137525657..137998394) Genome browser AA seq 8827 aa AA seqDB search MAASRTASRSPRDIANVMQRLQDEQEIVQKRTFTKWINSHLTKRKPPLVVDDLFEDMKDG VKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEGRKIKLVNINSTDIADGRPS IVLGLVWTIILYFQIEELTSNLPQLQSLPGSTSSVDSMVSAETASPPSKRKVATKIQGNA KKALLKWVQYTVAKQTGIDVKDFGRSWRSGVAFHSVIHAIRPELVDLEKVKGRSNRENLE EAFTIAESELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDIHNTGTDGQENDEILP GFPSFANSIQNFKREDGLILKETKVWIEQFERDLTRAQMTESNLQDKYQSFKHFRVQYEI KRKQIEHLIQPVHRDGKLSLDQALVKQSWDRVSSRLFDWHIQLDKSLPAPLGTIGAWLYR AEVALREEITIQQVHEETANTIQRKREQHKDLLQNTDAHKRAFHEIYRTRSVNGIPVPPD QLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRESVELLL QNYISFIENSKFFEQYEVTYQILKQTAEMYVKADGSVEEAENVMKFMNETTAQWRNLSVE VRSVRSMLEEVIANWDRYGNTVASLQAWLEDAEKMLNQSEHAKKDFFRNLPHWIQQHAAM NDAGNFLIETCDEMVSRDLKQQLLLLNGRWRELFMEVKQYARADEMDRMKKEYADCITIL SDFATEAHKKLSEPLEVSFINVKLLIQDLEDIEQRVPVMDAQYKMITKTAHLITKESSQE EANEMFATMSGLKERLTKVKECCPPLLYESQQLLIPLEELEKQMTFFYDSLAKIHEIMAV LEREAQSSALFKQKHQELSACQESCKKTVTQIEKGSQNVQKFVTLSSVLKHFDQTKLHRQ IADAHGAFQNMVKKIGDWKKHVETNSRLMKKFEESRAELEKVLRIAQEGLEEKGNPEDLL KKHTEFFSQLDQRVLNAFLKACDELTDILPEQEQQGLQEAVRKLHKQWKDLQGEAPYHLL HLKIDVEKNRFLASVEECRTELDRETTLVPQEGSEKIIKEHRIFFSDKGPHHLCEKRLQL IEELCLKLPVRDPVRNTPETCHVTLKELRAAIDATYKKLVEDRDKWKDYTRRISEFSSWI SAKETQLKGFKNEPIDTANHGEIKHAVEEIRNGVTTKGETLNWLKSRLKILIEVSSENEA QKQGDELAKLSSSFKALIALLSEVEKMLSNFGDCVQYKEIVKSSLGELISDSKEVQEQAE KILDTENLFEAQQLLLHHQQKTKRISAKKRDVQQQIAQAQQGEGGMPGQVRDELRKLEST LDSMEHSREKQERRIQVTLRKWERFETNKETVVRYLFQTGSSHERFLSFSSLESLSSELE QTKEFSKRTEGIAVQAENLVKEASEIPLGPKNKQLLQQQAKTIKEQVKKLEDTLEEDIKT MEMVKNKWDHFGNNFETLSVWITEKEKELNALETSSSAMDMQINQIKVIIQETESKIGCI TELEEAAQSFAQFVTTGESARIKAKLTQIRRYWEELREHAQCLEGTILGHLSQQQKFEEN LRKIQKSVSEFEDKLADPIKICSSATETYKILQEHMDLCQALEALNSAVTTVSASAQKVA NRATSSIQEAAALQQRYEETRSRAKERQAVLENLLAHWQRLEKELSTFLTWLERCEAIAS SPEMDISADRVKVESELQSIQALQNELVSQASVYSNLLQLKESLFSVASKDDVKMMKLHL EQLDERWRDLPQIISKRINFLQSVVSEHQQFDELLLSFSVWIKLFLSELQTTSEISITDH QAAFARHKDHEVEAESKMGDLQRLRDHLAKLGALGRAEDLHLLQGKAEDCFQLFEEASQV VGRRQLALSQLAEFLQHHASLSGVLHRLRHTVETTDSMNKKQTDLLKKDLNRAIQDAKTL ESTAISLDGILAKAQYHLKSGSSEQRTSCRSTADHLCFELERIQNLLGTKQSEADALAVL KKAFQDQKEELLKSIEDIEERTDKERLKEPTRQALQQRLRVFNQLEDELNSHEHELCWLK DKAKQIAQKDVAFASEVDREINRLEVTWDDTKKLIHENQGQCCGLIDLMRDYQNLKSVVS KVLENANNVLATRTTVKDQEDLKWALSKHESVKNEMCNKQKELDNFTSKGKQLLSELKKI HSSDFNLVKTDMESTVDRWLDVSEKIEENMDRLRASLTIWGDVLSSKDEIDGWSNNSVPQ LAESISNLNNSVRAEEYLKEFESEVKNKALRLEELHCKVNDLKELTKNPETPPDLQFIEA DLRQKLEHAKEITEEAKGTLREFTTQSTQVEKFINDITSWLTKVEEVLMNCAQTETWEGL KKVKEIQKELQSQQSNISSTQENLNSLCRKYHSMELESLGSAMTGLIKNHEAVSQLCSKT QASLQDFLEKHFNESMQEFQEWFSGIKAAAKKSSDRTGDSKVLEAKLHDLQNILDSISDG QSKLDAVTQEGQTLYAHLSKQIVSSIQEQVTKANEEFQAFLKQCLKDKQALQDCALELGS FEDQHRKLNLWIHEMDERLSTENFGESKQHIPEKKNEVHKVEMFLGELLAVRESLDKLSQ RGQLLSEEGHGAGKEGRLCSQLLTNYQNLLRTTKEKLRNCQLALQEHEALEEAVQSMWSW VKDIQDKLACAESTVGSKDTLEKRLLQIQDILLMKGEGEVKLNMAIGKGEQALRSSNKQG QKVIQTQLQNLKDVWADIMSSSLRAQSTLESVISKWNDYLEWKNQLEQWMEFVDQKVEHP LQPQPGLKEKFSLLDHFQSIVSEAEDHAGTLHRLASKSRELYQKTEDESFKETAQEELKT QFNDIITVSKEKMRKVEEIVKDHLMYLDAVQEFTDWLHSAKEELHRWSDMSGDSSATQKK LSKIKELMDSRGIGASRLSRVESLAPAVRQNTSASGCELVDAEMQALRADWKQWEDSVLQ TRTSLENLVSQMALSEQEFSGQVVQLEQALEQFGALLTTCAQQLALLESKNTDKEIVECW RKGQEILDALQKAEPKTEDLKSQLNELCRFSRDLSTYSGKVSGLIKEYNCLCLQASKGCQ TREQILQQRFQRAFKDFQQWLVNAKITTAKCFDIPQNISEVSTSLQKIQEFLSESENGQH KLNVMVSKGELLSTLLPKEKADGIQAKVATAKEDWKKFHSNLHQKESALENLKIQMKDFE VSAEPVQDWLSKTEKLVQESSNRLYDLPAKRREQQKLQSVVEEINCYEPQLNRLREKAQQ LWEGQAASKSFMHRVSQLSSQYLALSNLTKEKVSRLDRIVAEHNQFSLGIKELQDWMTDA VHMLDSYCHPISDKSVLDSRMLKLEALLSVKQEKEIQMKMIVTRGESVLQNTSPEGWPAI QQQLQSVKDMWASLLSTAIRCKSQLEGALSKWTSYQDDVRQFSSWMDSVEASLNESERQY AELREKTASLGKAKLLSEEVLSYSSLLEAIELKGAGMTEHYVTQLEFQDLQERYRAITER AKEAVAKSEKLVRLHQEYQRDLKAFEVWLGQEQEKLDRYSVLEGDAHTHETTLRDLQELQ VHCAEGQVLLNSVLHTREEVIPSGIPQTEDRALESLRQDWQAYQQRLSETRTQFNNVVNK LRLMEQKYQQVDEWLKTLEDKVSLRTGRQSNRAAKEIQLHQMKKWHEEVIAYKDEVEDVG ARAQEMLDENHVSSSMGCQATQLTSRYQALLLQVLEQIRFLEEEIQSLEESELSLSSYSD WYSSTHKNFKNVATKIDRVDKATMGKKMKTLEGLLKDMDKGHSLLKSAREKGERALKYLE DGEAEMLRKDIHEHVEQLKELTSTVRKEHMTLEKGLLLAKEFSDKYKALTQWISEYQEIL HTPEEPKMELYEKKAQLSKYKSLQQMVLSHEPSIKSVREKGEALLELVQDVTLKDKMDKL QSDYQDLCGAGKEHVCSLEMKVKDHEDYNSELQEVEKWLLQMSGRLVAPDLMETSSLETI TQQLAQHKAMMEEIAGFEDRLNNLKSKGDNLISQCADHLQAKLKQNVYAHLQGTKDSYSA VCSTAQRVYQSLEHELQKHVSRQDTLQQCQAWLSAVQPDLKPTQHPPLSRAEAVKQVKHY RALQEQARTYLDLLCSTCDLSSSSVKTTAKDIQETEQMIEQRLVQAQNLTQGWGEIKHMK AELWIYLQDADQQLQNMKKRHSELELNIAQNMVSQVKDFVKKLQCKQASVTAITERVNKL TKKQESPEHKEISHLNDQWLDLCLQANSLCLQREEDLQRTRDYHDRMNVVEEFLEKFTTE WDNLARSDAESTAVHLEALKKLALALQERKQAVEDLKDQKQKMIEHLNLDDKELVKEQTS HLEQRWFQLEDLVKRKLQVSVTNLEELNVVRSRFQELMEWAEEQQPNIAEALKQSPPPDM AQNLLMDHLAICSELETKQMLLKSLIKDADRVMADLGLNERQIIQKALSDAQRHVNCLSD LVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDDVSKQVKTCKSA QASLKTYQNEVTGLWAQGRELMKGATEQEKSEVLGKLQELQSVYDTVLQKCSHRLQELEK SLVSRKHFKEDFDKACHWLKQADIITFPEINLMNESAELHAQLAKYQHILEQSPEYENLL LTLQRTGQAILPSLNEVDHSYLNEKLNALPLQFNVIVALAKDKFYKVQETILARKEYASL IELTTQSLSELEDQFLKMSKVPTDLRVEEAVSLQEGCRALLGEVARLGEAVDELNQKKES FRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVGLLEDTSSAYQEHEKMCHQLEKQLQAVKT EQSKVNEETLPAEEKLKIYHLLAGSLQDAGIVLKRVTVHLEDLVPHLDPSAYEKAKQQIQ SWQEELKVLTSAIGATVTECESRMVQSIDFQTELSRSLDWLRSVKAELSGPVCLDLSLQD IQEEIRKTQIHQEEVQSSLRIMNALSNKEKEKFTKAKELLSADFQHTLAELSELDGDVQE ALRTRQAALTQIYSQCQRYYQVFQAANDWLEDAHEMLQLAGNGLDVESVEENLKNHVEFF STEDQFHSNLEELQHLVASLDPLIKPTGKEHLAQKMASLEEKSQRIIQDSHAQLDLLQRC ADQWQNYQKAREEVIELMNEAEKKLSEFSLLKTSSSHEAEEKLSEHKALASVVNSFHEKV VALEDKTSQLEKTGNDASKAAISRSMTTVWQRWTRLRAVAQDQEKILEDAVDEWTSFNNK VKKATETTDQLQDKLPGGSAEKASKAELLTLLDHHDALVLELEQQQLALGMLRQQALGML QDGAPQPPGEEPPTVQEITAMQDRCLNMQEKVKNAGKVVKQELKEREVVETQINSVKSWV QETKEYLGNPTIEIDAQLEELQLLLTEATNHRQSIEKMAEEQKNKYLGLYSILPSELSLQ LAEVALDLGTIHDQIQDKVREVEQSKAMSQEFSRQIQKIAKDLTTILSKLRAKTDNLQQA KIDQKVLGEELDGCNLKLMELDAAVQKFSEQNGQLGKPLAKKVGKLMELHQQTIRQAENR LSKLSQAASHLEEYTEMLEFILKWIEKAKVLVHGKIAWNSANQLREQYIFHQTMLEESEE IPSNLEAMIEKLQCLASIYSTEKMSQQVADLGRESEELRQTIKIRLQNLQDAAKDMKKFE TELKNLQVALEQAQTTLTSPEVGRLSLKEQLSHRQHLLSEMESLKPKVHAVQICQSALRI PDDVVASLPLCHCALHLQAEASRLQHTAIQQCNIMQEAVVQYEQYEQEMQHLQELIEGAH REIEDTPAATSNIQELQAQISRHEELAQKIKGYQEQIASLNSKCKMLTMKAKHATMLLTV TEVEGLAEGTEDLDRELLPATSAHPSVVMMTAGRCHTLLSPVTEESGEEGTNSEISSPPA CRSPSPVANTDASVNQDIAYYQALSAERLQTDAARIHPSTLPSPEFYELGLEPSATAKLD DLQRSWETLKNVISEKQRTLYEALERQQKYQDSLQSISTKMEAIEMKLSESLEHGRGPES QMAEHQSSPQALMDEILMLQEEISELQSSLAEELVSQSPESDPAEQLALQSTLTVLAERM STIKMMASGKRQLLEEKLNDQLEEQRQEQALQRYRCEADELDHWLLSTKATLDTALGTAQ EPMDMEAQLVDCQNMLVEIEQKVVALSELSVHNDNLLLEGKAHTKEEAEQLAVKLRTLKG SLLELQRALHDKQLLMQQGTAQEKEESHADLTASQSPGVQEWLAQARTAWAHQRQSSLQQ QKELEQELAEQKSLLRSVASRGEEILTQHSAAETSAGIGEKPDVLSQELGMEGEKSASED QMRMKWESLHQEFSTKQKLLQNVLEQEQEQVLYSRPNRLLSGVPLYKGDGQTQDRSAVTS LLDGLNQAFEEVSSQGGGTKRQNIHFEQKLYDGVSATSTWLDDVEERLFVAAALLPEETE ACLFNQETLAKDIKEMSEEMDKNKNLFSQAFPENGDNRDVIEDTLGCLLGRLSLLDSVVN QRCHQMKERLQQILNFQNDLKVLCTSLADSKYIILQKLANVFEQPVAEQIEAIQQAEDGL KELDAEIIELKKHGDKLQIEQPSMQELSKLQDMYDELMMTIGSWRSSLNQNLALKSQYER ALQDLADLLETGQEKMAGDQKIIVSSKEEIQQLLDKHKEYFQGLESHMILTETLFRKIIN FAVLQETQFHTELMTQASAVLKRAHKRGVELEYILETWSHLDEDHQALSKQLEVVESSIP SVGLVEESEERLIDRITLYQHLKSSLHEYQPKLYQVLDDGKRLLISISCSDLESQLNQLG EQWLDNTNKVSKELHRLETVLKHWTRYQSESAELIHWLQSAKDRLEFWTQQSVTVPQELE MVRDHLNAFLEFSKEVDAKSSLKSSVLSIGNQLLRLKKVDTASLRSELSHIDSQWTDLLT NIPTVQEKLHQLQMDKLPSRHAISELTTWISLMENVIQKDEENIKNSIGYKAIHEYLQKY KGFKIDINCKQLTVDFVNQSVLQISSQDVESKRSDKTDFAEQLGAMNKSWQILQGLVTEK IQLLEGLLESWSEYENNVQSLKTWYETQEDKLKQQHRIGDQASVQSAMKDCQDLEDLIRA KEKEVEKIEQNGLALIQNKKEEVSGVVMSTLRELNQTWANLDHMVGQFKILLKSVFDQWN NHKEAFDEINSYLMEARYSLSRFRLLTGSLEAVQVQVDNLQNLQDDLEKQEKNLQNFGSI TNQLLKECHPPVTETLTTTLKDVNMRWNNLLEEIAKQLCSSKALLQLWQRYKDYSKQCAS TVQQQEDGASELLKAATNKDIADDEAATWIQDCNDLLKGLGTVKDSLFVLRELGEQLKQQ VDASAASTIQSDQLSLSQRLCALEQALCKQQTMLQAGVLDYETFTKSLEALEAWIVEAEE ILQGQDPGHSSDLSTIQQRMEELKGQMLKFSSMAPDLDRLNELGYRLPLNDKEIKRMQNL NRHWSLISSQTTERFSKLQSFLLQHQTFLEKCETWMEFLVQTEQKLAVEISGNYQHLLEQ QRAHELFQAEMFSRQQILHSIIIDGQRLLEQGQVDDRDEFNLKLTLLSNQWQGVIRRAQQ RRGIIDSQIRQWRRYREMAEKLRKWLVEVSYLPVSALGSVPIPLQQARTLFDEVQFKEKV FLRQQGSYILTVEAGKQLLLSADSGAEAALQAELAEIQEKWRSASVHLEEQKKKLAFLLK DWEKCENGIADSLEKLRTFKKKLSPPLPDHHEELHAEQMRCKELENAAGNWTDDLAQLAL LKDTLCAYISADDISILNERMELLQRQWEELCHQLSLRRQQVSERLNEWAVFSEKNKELC EWLTQMESKVSQNGDILIEEMIEKLKKDYQEEIAVAQENKIQLQQMGERLARASHESKAS EIEYKLGKVNDRWQHLLDLMAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIV YDSCDSDEIQKKLTEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQAT RNLDRRWRNICAMSMERRLRIEETWRLWQKFLDDYSRFEDWLKISERTAAFPSSSGVLYT VAKEELKKFEAFQRQVHESLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNLQ KRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQ QEISLNHNKIEQIISQGEQLIEKSEPLDAAVIEEELDELRRYCQEVFGRVERYHKKLIRL PLPDDEHDLSDRELELDDSAALSDLHWRDTSADSVLSPQPSSNPSLSLAQPLRSERSGRD TPASVDSIPLEWDHDYDLSRDLESAVSRTLPSEDEEVGDDKDFYLRGAVGLSDVMIPESP EAYVKLTESAIRNTSGAPSALESQIRQLDKALDESRFQMQQTENIIRSKTPTGPELDSSY RGYMKLLGECSGSIDSVRRLEHKLKEEEENFPGFVNLNSTETQTAGVIDRWELIQAQALS KELRMKQNLQKWQQFNSDLNNIWTWLGETEEELERLQHLELSTDIQAIELQIKKLKELQK AVDHRKAIILSINLCSPEFTQTGSEKSQDLQDRLSQMNGRWDRVCSLLDEWRGLLQDALM QCQDFHEMSHGLLLMLENIDRRKNEVVPIDSNQDAETLQDHHKQLMQIRHELLESQLKVA SLQDMSCQLLVNAEGTDCLEAKEKVHVIGNRLKLLLKEVSRHIKELEKLLDMSSSQQDLS SWSSADELDTSGSVSPTSGRSTPNRQRTPRGKCSLSQPGPSVNSPHSRSIKGGCDSSLSE PRPARSGRAFLLRVLRAALPLQLLLLLLIGLACLVPMSEEDYSCALSNNFARSFHPMLRY TNGPPPL NT seq 26484 nt NT seq  +upstreamnt  +downstreamnt atggctgcctccaggacggcctcacggtctccccgggacattgccaatgtgatgcaaagg ttgcaagatgagcaagagatagtacaaaaacgtactttcacgaaatggatcaactcgcat ctgaccaagcggaaacccccactggtggtagatgatctttttgaagacatgaaagatggc gttaagctgcttgctcttctggaggtcctgtccgggcagaaactgccttgtgaacaagga cgccgtatgaagcgaatccatgctgtggctaatattggcacagcactgaagttccttgaa ggaaggaagattaaactagtcaacattaactccaccgatatagcagatggccggccatca atagttctcggattggtgtggaccattattctgtatttccagattgaggagctgaccagc aacctgccgcagctgcagtccctgcctggcagcacatcctctgtggacagcatggtcagc gcggagaccgccagccccccgagtaagcggaaggtggccaccaagatccaaggaaatgct aagaaggctttattaaagtgggttcagtacacagtagccaagcagacgggaatagacgta aaggacttcgggcggagttggagaagtggagttgcctttcattcggtcatccatgccatt cgaccagaactagtggacttggagaaagtgaaaggcagatctaaccgggaaaacctggag gaagctttcactattgctgaatcagaactaggaattccaagactactggatcctgaagat gttgatgtggataaaccagatgagaagtctattatgacctatgtagcccagtttctgaag cattaccctgacatccacaacacaggcactgatgggcaagagaatgatgaaatacttcca ggttttccatcttttgcaaattctatccaaaattttaagagagaagacgggctaattttg aaggaaacaaaagtctggatagaacaatttgaaagagatttgacaagggcacagatgacg gaatcaaatttacaggataaatatcagtcatttaagcacttcagagttcaatatgaaata aaaaggaagcagatcgaacatttaatacaaccagtacatagagacggtaaattgtcactt gaccaagcattggtaaagcagtcctgggatagagtgtcctccaggctctttgactggcat atacagcttgataaatctctccctgcacctctgggcaccataggtgcctggttatacaga gcggaggtggccctgagagaggaaataaccattcagcaggtgcacgaggaaacggccaac acaatacaacggaaacgcgagcaacacaaggatctgcttcaaaacacagatgcccacaaa agagcattccatgaaatctaccggaccagatctgttaacgggatcccagtaccacctgat caattagaggacatggccgagaggtttcattttgtttcctccacatcagagctacactta atgaaaatggaatttctagaattaaagtaccgtctgctctcactgctggttcttgcagag tcaaagctgaaatcttggatcatcaagtatgggaggagagagtccgtggagctccttcta cagaactacatctcttttatagaaaatagcaagttctttgaacaatatgaagtgacatac cagatcttgaaacagacagctgagatgtacgtcaaagctgatggttcagtggaagaagct gagaatgtgatgaaattcatgaatgaaaccacagcccagtggaggaacctctcagtagag gtcaggagcgtgcgaagcatgctggaagaagtcatcgcgaactgggatcgatatggcaat actgtggctagtcttcaggcctggctggaggatgctgagaaaatgctaaatcaatcagag catgccaaaaaggatttttttcgaaacttgcctcactggatacagcagcacgctgccatg aatgatgctggcaattttctaattgaaacatgtgatgaaatggtttcccgagatcttaaa cagcaattgctattgctcaatggacggtggagggaattgtttatggaagtcaagcaatat gctcgggctgatgagatggacagaatgaagaaggagtatgcagactgtattactatcctg tctgattttgcaactgaagcccataagaaactttctgaacccttagaagtctcttttatt aatgtcaagttattaattcaagacttggaggacattgagcagcgggtacctgtaatggat gctcagtacaagatgattaccaagaccgcacacctcattaccaaggagagctcccaagaa gaagccaatgaaatgtttgcaaccatgtctgggctcaaagaacggctaaccaaggtcaaa gaatgttgccctccactcctttatgagtctcagcagctgttgatcccattggaagaactg gagaagcagatgacgttcttttatgactcgcttgcgaaaatccacgaaattatggcagtt ctcgagcgtgaagcacaatccagtgccctttttaaacagaaacatcaggaactgtcagct tgtcaagagagctgtaagaaaaccgtgacgcagatagagaaaggcagtcaaaatgttcaa aagtttgtgaccttgagcagtgtgttaaagcattttgatcagacgaagctgcacagacag attgcagatgcccacggtgctttccagaatatggtgaagaaaattggagactggaagaaa catgtggaaaccaatagtcgcttgatgaagaaatttgaagagtctcgagcagagctggag aaggtgctacggatcgctcaggagggcctggaggaaaaggggaacccagaagacctcctg aagaaacatacagaatttttcagtcagctggatcagagagtgctcaatgctttcctgaaa gcttgcgacgagctcactgacatcctccctgagcaggaacagcagggcctgcaggaagct gttagaaagctccataaacagtggaaggaccttcaaggagaagccccatatcatttgctt catctgaagattgatgtggagaagaatagattcctagcttctgtagaagaatgcagaact gagctggatcgagagaccacgctggtgccccaggaaggcagtgaaaagattattaaggag cacaggattttcttcagtgacaaaggtcctcatcatctttgtgagaaaaggttacagctt attgaagaactgtgtctgaaactccccgtccgggacccagtaaggaacacacctgaaacc tgtcacgtgactctcaaagagctcagagctgccattgacgccacctacaagaagctcgtg gaagaccgggacaagtggaaggactacactagaagaatttctgagttctcatcttggata tctgcaaaggagacacaattgaaagggtttaagaatgagcccatcgataccgccaaccat ggagagattaaacatgccgtagaggagatcagaaatggtgttaccacaaagggcgagact ctcaactggctgaaatccaggcttaaaattttaattgaagtttcttctgagaatgaagcc caaaagcaaggagatgagttggcaaaattatctagttctttcaaggctctcatagctttg ttgtcagaggttgaaaagatgttaagcaactttggggactgtgtccagtacaaagaaata gtcaaaagttcccttggagagttgatttctgactctaaagaagtccaggagcaagctgag aagatcttggacactgaaaatctgtttgaagcacagcaattacttcttcatcaccagcaa aagacaaagaggatttctgcgaagaagagagacgtgcagcagcagatagcacaggctcag caaggagaaggtgggatgcccggccaagtccgggacgagctgcggaagctggagagcacc ctggacagcatggagcacagcagagagaagcaggaacgccgcatccaggtcacattaaga aagtgggagcgatttgaaacaaacaaagagacagtggtcagatacctttttcaaacaggt tccagccatgagcgctttttgagttttagcagtttggaaagtttatcttcagaattggaa cagacaaaggagttttctaaacgaacagaaggtattgcagtccaggctgagaatcttgtg aaggaagcttccgagataccacttgggcccaagaataagcagctgcttcaacagcaggcc aagacaatcaaagagcaagtcaaaaaattagaagacacacttgaagaagatattaaaacc atggaaatggtgaaaaacaagtgggatcattttggcaataattttgagaccctgtccgtc tggataactgagaaagaaaaagaactcaatgccttggaaacttcatcatctgccatggac atgcaaatcaaccagattaaggtcataattcaggaaacagaaagcaagatcggctgcatt 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cagatgagaatgaaatgggaaagcctacatcaagaatttagtaccaagcagaaactacta cagaatgttctggaacaggaacaagagcaagtgctctacagcaggccaaatcggctcctg tctggcgtgccactgtacaaaggggatgggcagacccaagacagatctgcagtgacgtct ttactggatggattgaaccaggcgtttgaggaggtttcgtcccagggtggggggacaaag aggcagaacattcacttcgaacagaagttatatgatggggtctcagctacctctacatgg ttggatgatgtggaggaacgcttatttgttgccgcagcacttttaccagaagaaaccgaa gcttgcctcttcaaccaagagactcttgccaaagatattaaggaaatgtctgaagaaatg gataagaacaagaacttgttttcccaagcatttccagagaatggtgataaccgagatgtt attgaagacactttgggttgtcttttgggccggttatccttgttagactcagtagtgaat cagcgatgtcatcagatgaaggaaagacttcagcaaatactaaattttcagaatgatctg aaggtgctgtgtacatcattggccgacagcaaatacatcattctgcagaaactggcaaat gtgtttgaacagcccgtggcagagcaaattgaggcaatacaacaggctgaagatgggcta aaggagttggatgcagaaatcattgaattaaaaaagcatggtgacaagttgcagattgag cagccttccatgcaggaactgtccaaacttcaggacatgtatgatgaactgatgatgacc attggctcctggcggagtagtctgaaccagaatcttgccctcaagagtcagtacgaaagg gccctacaagatctggctgacctgctggagactggacaggagaagatggcaggtgaccag aaaatcattgtgtcttccaaggaggaaattcaacaactgcttgacaaacataaggaatac ttccaaggcctggaatctcatatgatcctgacggagacactcttcagaaagataatcaac tttgcggtcctacaagaaacgcagttccacacagaactgatgacacaggcttcagctgta ctgaaacgggctcacaagaggggtgtggagttggagtacattctagagacatggtctcat ctggatgaagaccaccaggcgctcagcaaacagctggaggtggtggaaagtagcatccca agtgtgggattggtggaggagagcgaggagaggctcatcgaccggataacactctaccag catttgaaatccagccttcatgaataccagcccaaattatatcaggtgttagatgatgga aaacgactgctcatatccattagctgctcagatctagaaagccagctcaatcaactggga gaacagtggttggataataccaacaaagtgtcaaaggaacttcaccgattggaaacagta ctgaaacactggaccagatatcaaagcgaatctgcagaacttattcactggttacagtct gcaaaagacaggctagaattttggactcaacagtctgtgacagtcccacaagaactggaa atggtccgtgatcatctaaatgctttcctggagttttccaaagaagtggatgcgaaatct tccctgaaatcatctgttctgagcatcggaaatcagcttcttcgattaaagaaagtggac acggcttccctacgttcagaactgtcacacattgacagccagtggactgatctgctgaca aatattccgactgtacaggaaaagctccaccagctccagatggataagctgccgtcccgc catgccatttctgaactgacgacttggatttctctaatggaaaatgttattcaaaaggat gaagagaacataaaaaattcgataggttacaaggcaattcatgaataccttcagaaatac aagggttttaagatagatattaactgtaaacagttgacagttgattttgtgaatcagtcc gtgctacaaatcagcagtcaggatgtggaaagtaaacgcagtgacaagactgattttgct gagcaacttggagccatgaataaaagttggcaaatcctgcagggcctagtgactgagaag atccagcttttggaaggcttattggaatcttggtcagaatatgaaaataatgtgcaaagt ctgaaaacttggtatgaaacccaggaagacaaactaaaacaacagcatcgaattggagat caggcttcagttcaaagcgcaatgaaagactgtcaggatctagaagatttgattagagca aaagaaaaagaagtagagaaaattgagcagaatggacttgctttgattcagaacaagaaa gaagaagtctctggtgttgtcatgagcacgctgcgggagctcaaccaaacctgggcaaat ttagaccacatggttgggcagttcaagatactgttgaagtccgtgtttgaccaatggaac aatcacaaggaggcctttgatgagataaacagttacctcatggaggccagatattctctt tcccgcttccgcctgctgactggttctttagaagctgtacaagttcaggtagacaatctt cagaatcttcaagatgatctggaaaaacaggaaaagaacttacagaattttggttccatc accaaccaactgttaaaagaatgtcacccacctgtgacagaaactcttaccaccacatta aaagatgtcaatatgagatggaataacttgctggaagagattgctaagcagctgtgctcc agcaaggcactccttcaactttggcaaagatacaaggactactccaaacagtgtgcttct acggttcagcagcaggaggatggagccagtgagctcctgaaggcagccactaacaaggac attgccgatgacgaagctgcgacgtggattcaggattgcaacgatctcctcaaaggcttg gggacagtgaaggattccctttttgttctccgtgagctgggagagcagctcaagcaacaa gtggatgcttcagcggcatcaaccattcaatccgatcagctgtccttgagtcaacgctta tgtgccctagaacaggctctctgcaagcagcagaccatgttacaggctggagttcttgac tatgaaacctttaccaagagtttagaagctttggaggcctggatagtagaagcggaagaa atattgcaagggcaggaccctggccactcttctgacctctcaaccatccagcaaaggatg gaagaacttaagggacagatgttaaaattcagcagcatggccccagatttagaccgtcta aatgagcttggatataggctacccctgaatgataaagaaatcaaaaggatgcaaaatctg aaccggcactggtctctgatctcctctcagacaacagagagattcagtaagttgcagtcg tttttgctacaacatcagactttcttggaaaaatgtgaaacatggatggaattcctggtt caaacggaacaaaagttagcagtagagatttctggcaattatcagcatcttttggagcag cagagagcacatgagttgtttcaagcagagatgttcagtcgtcagcagattttgcactcg atcattattgatgggcagcgtcttctagaacaaggtcaagttgatgacagggatgaattc aacctgaaactgacccttctcagcaatcagtggcagggagtgattcgcagggcccagcaa aggaggggcatcatcgacagccaaattcgccagtggaggcggtacagggagatggcagaa aagcttcgtaaatggttggttgaagtgtcctatcttcccgtgagtgctcttggaagtgtc ccaataccactgcagcaggcaaggaccctctttgatgaagtgcagttcaaagaaaaagtg ttcctgcgacaacaaggcagctacatcctaacagtggaggctggcaagcagcttctgctc tcggccgacagtggagctgaggccgccttgcaggcggaacttgctgaaatccaagagaaa tggagatcggccagtgtgcatctggaggaacagaagaaaaagctggccttcttgctgaaa gactgggaaaaatgtgagaatggtatagctgattctctggagaagctacggactttcaaa aagaagctgtctccacccctgccagatcaccacgaagagctccatgcagagcaaatgcgt tgcaaggagttggaaaatgcagctgggaactggacagatgacttggctcagttggctctg ctgaaggacaccctctgtgcctacatcagcgccgatgatatctccatcctgaacgaacgc atggagcttctgcagagacagtgggaagaactgtgccaccagctctccttaaggcggcag caagtgagtgagagattgaatgaatgggctgtcttcagtgaaaagaacaaggagctttgc gaatggctgacccagatggaaagcaaagtttctcaaaatggagacattctcattgaagaa atgatagagaaactcaagaaggattatcaagaggaaattgctgttgcccaagagaacaaa atacagctccagcaaatgggagaacgacttgctcgagccagccatgaaagcaaagcctct gagattgaatacaagcttggaaaggtcaacgaccggtggcagcatctcctggatctcatg gcagccagggtaaagaagctgaaggagaccctggtggccgtacagcagctggataagaac atgagcagcctgaggacgtggctggctcacatcgagtcagagctggccaagcccatagtc tacgattcctgtgactcggatgaaatacagaaaaagcttactgagcagcaggagcttcag agagacatcgagaaacacagcacgggtgtggcgtctgtcctcaacctgtgtgaggtcctg ctgcatgactgtgatgcctgtgccacagatgcggagtgtgactccatccagcaggctacg cgaaacctggaccggcggtggaggaatatctgtgccatgtccatggagaggaggctcaga attgaagagacgtggcgattgtggcagaagtttctggacgattattctcgttttgaagat tggctcaagatttcagaaaggacagctgccttccccagctcttccggggtgctctataca gttgccaaggaagaactaaagaaatttgaggctttccagcgacaggtgcacgagagcctg acccagctggagctgatcaacaagcagtaccgtcgcctggccagagagaaccgcaccgat tctgcctgtagcctaaagcagatggttcacgaaggcaaccagagatgggacaacctgcag aagcgtgtcacctccatcttgcgcagactcaagcatttcatcggccagcgtgaggagttt gagactgcgcgggacagcattctggtgtggctgacagaaatggatctgcagctcactaat attgagcatttttctgagtgtgatgttcaagctaaaataaagcaactcaaggccttccag caggaaatctcactgaaccacaataagattgagcagataatttcccaaggagaacagctt atagagaagagtgagcccttggatgcagcggtcattgaggaggaactggatgaactccga cgttactgtcaggaggttttcgggcgcgtggaaagataccataagaaactgattcgcctg cctctcccagatgatgagcatgacctctctgaccgggagctggagctggatgactctgca gctctctcggacctccactggcgggacacctctgcagacagcgtgctttccccccagcct tcttccaacccctccctctcactcgcccagcccctgcggagcgagcggtcgggacgagac acccctgccagtgtggactcaattcccctggagtgggaccatgattatgacctcagtcgg gacctggagtctgctgtgtccagaactctgccctctgaggatgaagaggttggagacgat aaagatttctacctcaggggagctgttggcttatcagatgtaatgatccccgaaagtcct gaggcctatgtaaaactcacagaaagtgcaatcagaaatacctctggagcccccagtgcc ttagagtcacagatccgacaactagacaaagccttggatgagagccgttttcagatgcag caaactgaaaacatcatccgcagcaaaacccccaccggaccagagctagactccagctac agaggctatatgaaactactgggtgagtgcagtggcagcatagactccgtgaggagactg gaacacaaactgaaggaggaagaagagaactttccaggctttgttaacctgaacagtacg gaaacccaaacagctggtgtgatcgaccgatgggaactcatccaggcgcaggccctgagc aaggagctgaggatgaagcagaacctccagaagtggcagcagttcaactctgacctgaac aacatctggacgtggctgggggagacggaggaggagctggagcggctgcagcacctggag ctcagcaccgacatccaggcgatcgagctccaaatcaaaaagctcaaggagctccagaag gctgtggaccaccgcaaagccatcatcctctccatcaacctgtgcagccccgagttcacc cagactggcagtgagaaaagccaggatctgcaagatcgcctgtcccagatgaacggacgc tgggaccgcgtgtgctcgttgctggacgagtggcggggcctgctccaggatgcactgatg cagtgtcaggatttccatgaaatgagtcatggtttgcttcttatgctggagaacatcgac agaaggaaaaatgaagttgtccctattgattctaaccaggatgcagagacacttcaggac catcacaagcagcttatgcaaataaggcatgagctattggaatcccaactcaaagtggcc tcactgcaagacatgtcttgccaactactggtgaatgctgaaggcacagactgtttagaa gccaaagaaaaagtccatgtgattggaaatcggctcaaacttctcttgaaggaggtcagc cgacacatcaaggagctggagaagttattagacatgtcaagcagtcagcaggatttgtct tcctggtcttctgcggatgaactggacacctcgggatctgtgagtcctacgtcaggaaga agcaccccgaacagacaaagaacgccacgaggcaaatgtagtctctcacagcctggaccc tctgtcaacagtccacatagcaggtccataaaaggtggctgcgattcctccctttctgag cctcggccagctcggtccggccgggccttcttactcagagtcctccgcgcggcccttcca ctccagcttctcctgttgctcctcatcgggctcgcctgcctcgtaccaatgtcagaggaa gactatagttgtgccctctccaacaactttgcccggtcattccaccccatgctcagatac acaaacggccctcctccactctga

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