Prionailurus viverrinus (fishing cat): 125167382
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Entry
125167382 CDS
T09889
Symbol
IDH2
Name
(RefSeq) isocitrate dehydrogenase [NADP], mitochondrial isoform X1
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
pviv
Prionailurus viverrinus (fishing cat)
Pathway
pviv00020
Citrate cycle (TCA cycle)
pviv00480
Glutathione metabolism
pviv01100
Metabolic pathways
pviv01200
Carbon metabolism
pviv01210
2-Oxocarboxylic acid metabolism
pviv01230
Biosynthesis of amino acids
pviv04146
Peroxisome
pviv05230
Central carbon metabolism in cancer
Module
pviv_M00009
Citrate cycle (TCA cycle, Krebs cycle)
pviv_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
pviv00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
125167382 (IDH2)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
125167382 (IDH2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
125167382 (IDH2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
125167382 (IDH2)
Enzymes [BR:
pviv01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
125167382 (IDH2)
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GFIT
Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-GeneID:
125167382
NCBI-ProteinID:
XP_047717400
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All DBs
Position
B3:1077111..1094810
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AA seq
451 aa
AA seq
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MAGYLRVVRSLCRASGSGPAWAPAAPTGPNLQEQPRRHYADKRIKVAKPVVEMDGDEMTR
IIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSALATQKYSVAVKCATITPDE
ARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYK
ATDFVVDRAGTFKIVFSPKDGSGAKEWEVFNFPAGGVGMGMYNTDESISGFAHSCFQYAI
QKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKHKIWYEHRLIDDMVAQVLKS
SGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQK
GRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVQTVESGAMTKDLAGCIH
GLSNVKLNEHFLNTSDFLDTIKNNLDKALGQ
NT seq
1356 nt
NT seq
+upstream
nt +downstream
nt
atggctgggtacctgcgggtcgtacgctcgctctgcagggcctccggctccgggccggcc
tgggcgccggcagccccgacaggccccaacttgcaggagcagccgcggcgccactatgcc
gacaagaggatcaaggtggcgaagccggtggtggagatggacggcgatgagatgacccgg
atcatctggcagttcatcaaggagaagctcatcctgccgcacgtggatgtccagctcaag
tatttcgacctggggctcccaaaccgtgaccagaccaacgaccaggtcaccatagactcc
gcactggccacccagaagtacagtgtggctgtgaagtgcgccaccatcacccccgatgag
gcccgtgtggaagaattcaagctgaagaagatgtggaagagtcccaatggaaccatccga
aacatccttggggggaccgtcttccgggaacccatcatctgcaaaaacatcccacgcctc
gtccccggctggaccaagcccatcaccattggcaggcacgcccatggcgaccagtacaag
gccacggactttgtggtcgaccgggccggcacgttcaagatcgtcttctccccgaaggat
ggcagtggcgctaaggagtgggaagtgttcaatttccctgccggcggcgtggggatgggc
atgtacaacacggatgagtccatctcgggttttgcgcacagctgcttccagtatgccatc
cagaagaagtggccgctgtacatgagcaccaagaacaccatcctgaaggcctacgacggg
cgcttcaaggacatcttccaggaaatctttgacaagcactataagaccgacttcgacaag
cataagatctggtacgagcaccggctcattgatgacatggtggctcaggtcctcaagtct
tcaggcggcttcgtgtgggcctgcaagaactatgatggagacgtgcagtcggacatcctg
gcccagggctttggctccctcggcctgatgacgtctgtgctggtctgcccagatgggaag
accatcgaggctgaggccgctcatgggacggtcacccgccattatagggagcaccagaag
ggccggcctaccagcaccaaccccatcgccagcatctttgcctggacgcgtggcctggag
caccgggggaagctggatgggaaccaggacctcatcaggtttgcacagaccctggagaag
gtgtgtgtccagacggtggagagcggagccatgaccaaggacctggcgggctgcatccat
ggcctcagcaacgtgaagctgaacgagcacttcctgaacacctcggacttcctggacacc
atcaagaacaacctggacaaggccctgggccagtag
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