KEGG   Prionailurus viverrinus (fishing cat): 125167750
Entry
125167750         CDS       T09889                                 
Symbol
AKT1
Name
(RefSeq) RAC-alpha serine/threonine-protein kinase
  KO
K04456  RAC serine/threonine-protein kinase [EC:2.7.11.1]
Organism
pviv  Prionailurus viverrinus (fishing cat)
Pathway
pviv01521  EGFR tyrosine kinase inhibitor resistance
pviv01522  Endocrine resistance
pviv01524  Platinum drug resistance
pviv04010  MAPK signaling pathway
pviv04012  ErbB signaling pathway
pviv04014  Ras signaling pathway
pviv04015  Rap1 signaling pathway
pviv04022  cGMP-PKG signaling pathway
pviv04024  cAMP signaling pathway
pviv04062  Chemokine signaling pathway
pviv04066  HIF-1 signaling pathway
pviv04068  FoxO signaling pathway
pviv04071  Sphingolipid signaling pathway
pviv04072  Phospholipase D signaling pathway
pviv04140  Autophagy - animal
pviv04150  mTOR signaling pathway
pviv04151  PI3K-Akt signaling pathway
pviv04152  AMPK signaling pathway
pviv04210  Apoptosis
pviv04211  Longevity regulating pathway
pviv04213  Longevity regulating pathway - multiple species
pviv04218  Cellular senescence
pviv04261  Adrenergic signaling in cardiomyocytes
pviv04370  VEGF signaling pathway
pviv04371  Apelin signaling pathway
pviv04380  Osteoclast differentiation
pviv04510  Focal adhesion
pviv04517  IgSF CAM signaling
pviv04518  Integrin signaling
pviv04550  Signaling pathways regulating pluripotency of stem cells
pviv04611  Platelet activation
pviv04613  Neutrophil extracellular trap formation
pviv04620  Toll-like receptor signaling pathway
pviv04625  C-type lectin receptor signaling pathway
pviv04630  JAK-STAT signaling pathway
pviv04660  T cell receptor signaling pathway
pviv04662  B cell receptor signaling pathway
pviv04664  Fc epsilon RI signaling pathway
pviv04666  Fc gamma R-mediated phagocytosis
pviv04668  TNF signaling pathway
pviv04722  Neurotrophin signaling pathway
pviv04725  Cholinergic synapse
pviv04728  Dopaminergic synapse
pviv04810  Regulation of actin cytoskeleton
pviv04910  Insulin signaling pathway
pviv04914  Progesterone-mediated oocyte maturation
pviv04915  Estrogen signaling pathway
pviv04917  Prolactin signaling pathway
pviv04919  Thyroid hormone signaling pathway
pviv04920  Adipocytokine signaling pathway
pviv04922  Glucagon signaling pathway
pviv04923  Regulation of lipolysis in adipocytes
pviv04926  Relaxin signaling pathway
pviv04929  GnRH secretion
pviv04931  Insulin resistance
pviv04932  Non-alcoholic fatty liver disease
pviv04933  AGE-RAGE signaling pathway in diabetic complications
pviv04935  Growth hormone synthesis, secretion and action
pviv04936  Alcoholic liver disease
pviv04973  Carbohydrate digestion and absorption
pviv05010  Alzheimer disease
pviv05017  Spinocerebellar ataxia
pviv05132  Salmonella infection
pviv05135  Yersinia infection
pviv05142  Chagas disease
pviv05145  Toxoplasmosis
pviv05152  Tuberculosis
pviv05160  Hepatitis C
pviv05161  Hepatitis B
pviv05162  Measles
pviv05163  Human cytomegalovirus infection
pviv05164  Influenza A
pviv05165  Human papillomavirus infection
pviv05166  Human T-cell leukemia virus 1 infection
pviv05167  Kaposi sarcoma-associated herpesvirus infection
pviv05168  Herpes simplex virus 1 infection
pviv05169  Epstein-Barr virus infection
pviv05170  Human immunodeficiency virus 1 infection
pviv05200  Pathways in cancer
pviv05205  Proteoglycans in cancer
pviv05207  Chemical carcinogenesis - receptor activation
pviv05208  Chemical carcinogenesis - reactive oxygen species
pviv05210  Colorectal cancer
pviv05211  Renal cell carcinoma
pviv05212  Pancreatic cancer
pviv05213  Endometrial cancer
pviv05214  Glioma
pviv05215  Prostate cancer
pviv05218  Melanoma
pviv05220  Chronic myeloid leukemia
pviv05221  Acute myeloid leukemia
pviv05222  Small cell lung cancer
pviv05223  Non-small cell lung cancer
pviv05224  Breast cancer
pviv05225  Hepatocellular carcinoma
pviv05226  Gastric cancer
pviv05230  Central carbon metabolism in cancer
pviv05231  Choline metabolism in cancer
pviv05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pviv05415  Diabetic cardiomyopathy
pviv05417  Lipid and atherosclerosis
pviv05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pviv00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    125167750 (AKT1)
   04012 ErbB signaling pathway
    125167750 (AKT1)
   04014 Ras signaling pathway
    125167750 (AKT1)
   04015 Rap1 signaling pathway
    125167750 (AKT1)
   04370 VEGF signaling pathway
    125167750 (AKT1)
   04371 Apelin signaling pathway
    125167750 (AKT1)
   04630 JAK-STAT signaling pathway
    125167750 (AKT1)
   04668 TNF signaling pathway
    125167750 (AKT1)
   04066 HIF-1 signaling pathway
    125167750 (AKT1)
   04068 FoxO signaling pathway
    125167750 (AKT1)
   04072 Phospholipase D signaling pathway
    125167750 (AKT1)
   04071 Sphingolipid signaling pathway
    125167750 (AKT1)
   04024 cAMP signaling pathway
    125167750 (AKT1)
   04022 cGMP-PKG signaling pathway
    125167750 (AKT1)
   04151 PI3K-Akt signaling pathway
    125167750 (AKT1)
   04152 AMPK signaling pathway
    125167750 (AKT1)
   04150 mTOR signaling pathway
    125167750 (AKT1)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    125167750 (AKT1)
   04518 Integrin signaling
    125167750 (AKT1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    125167750 (AKT1)
  09143 Cell growth and death
   04210 Apoptosis
    125167750 (AKT1)
   04218 Cellular senescence
    125167750 (AKT1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    125167750 (AKT1)
   04550 Signaling pathways regulating pluripotency of stem cells
    125167750 (AKT1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    125167750 (AKT1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    125167750 (AKT1)
   04613 Neutrophil extracellular trap formation
    125167750 (AKT1)
   04620 Toll-like receptor signaling pathway
    125167750 (AKT1)
   04625 C-type lectin receptor signaling pathway
    125167750 (AKT1)
   04660 T cell receptor signaling pathway
    125167750 (AKT1)
   04662 B cell receptor signaling pathway
    125167750 (AKT1)
   04664 Fc epsilon RI signaling pathway
    125167750 (AKT1)
   04666 Fc gamma R-mediated phagocytosis
    125167750 (AKT1)
   04062 Chemokine signaling pathway
    125167750 (AKT1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    125167750 (AKT1)
   04922 Glucagon signaling pathway
    125167750 (AKT1)
   04923 Regulation of lipolysis in adipocytes
    125167750 (AKT1)
   04920 Adipocytokine signaling pathway
    125167750 (AKT1)
   04929 GnRH secretion
    125167750 (AKT1)
   04915 Estrogen signaling pathway
    125167750 (AKT1)
   04914 Progesterone-mediated oocyte maturation
    125167750 (AKT1)
   04917 Prolactin signaling pathway
    125167750 (AKT1)
   04926 Relaxin signaling pathway
    125167750 (AKT1)
   04935 Growth hormone synthesis, secretion and action
    125167750 (AKT1)
   04919 Thyroid hormone signaling pathway
    125167750 (AKT1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    125167750 (AKT1)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    125167750 (AKT1)
  09156 Nervous system
   04725 Cholinergic synapse
    125167750 (AKT1)
   04728 Dopaminergic synapse
    125167750 (AKT1)
   04722 Neurotrophin signaling pathway
    125167750 (AKT1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    125167750 (AKT1)
  09149 Aging
   04211 Longevity regulating pathway
    125167750 (AKT1)
   04213 Longevity regulating pathway - multiple species
    125167750 (AKT1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    125167750 (AKT1)
   05205 Proteoglycans in cancer
    125167750 (AKT1)
   05207 Chemical carcinogenesis - receptor activation
    125167750 (AKT1)
   05208 Chemical carcinogenesis - reactive oxygen species
    125167750 (AKT1)
   05230 Central carbon metabolism in cancer
    125167750 (AKT1)
   05231 Choline metabolism in cancer
    125167750 (AKT1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    125167750 (AKT1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    125167750 (AKT1)
   05212 Pancreatic cancer
    125167750 (AKT1)
   05225 Hepatocellular carcinoma
    125167750 (AKT1)
   05226 Gastric cancer
    125167750 (AKT1)
   05214 Glioma
    125167750 (AKT1)
   05221 Acute myeloid leukemia
    125167750 (AKT1)
   05220 Chronic myeloid leukemia
    125167750 (AKT1)
   05218 Melanoma
    125167750 (AKT1)
   05211 Renal cell carcinoma
    125167750 (AKT1)
   05215 Prostate cancer
    125167750 (AKT1)
   05213 Endometrial cancer
    125167750 (AKT1)
   05224 Breast cancer
    125167750 (AKT1)
   05222 Small cell lung cancer
    125167750 (AKT1)
   05223 Non-small cell lung cancer
    125167750 (AKT1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    125167750 (AKT1)
   05170 Human immunodeficiency virus 1 infection
    125167750 (AKT1)
   05161 Hepatitis B
    125167750 (AKT1)
   05160 Hepatitis C
    125167750 (AKT1)
   05164 Influenza A
    125167750 (AKT1)
   05162 Measles
    125167750 (AKT1)
   05168 Herpes simplex virus 1 infection
    125167750 (AKT1)
   05163 Human cytomegalovirus infection
    125167750 (AKT1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    125167750 (AKT1)
   05169 Epstein-Barr virus infection
    125167750 (AKT1)
   05165 Human papillomavirus infection
    125167750 (AKT1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    125167750 (AKT1)
   05135 Yersinia infection
    125167750 (AKT1)
   05152 Tuberculosis
    125167750 (AKT1)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    125167750 (AKT1)
   05142 Chagas disease
    125167750 (AKT1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    125167750 (AKT1)
   05017 Spinocerebellar ataxia
    125167750 (AKT1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    125167750 (AKT1)
   05418 Fluid shear stress and atherosclerosis
    125167750 (AKT1)
   05415 Diabetic cardiomyopathy
    125167750 (AKT1)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    125167750 (AKT1)
   04932 Non-alcoholic fatty liver disease
    125167750 (AKT1)
   04931 Insulin resistance
    125167750 (AKT1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    125167750 (AKT1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    125167750 (AKT1)
   01524 Platinum drug resistance
    125167750 (AKT1)
   01522 Endocrine resistance
    125167750 (AKT1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pviv01001]
    125167750 (AKT1)
Enzymes [BR:pviv01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     125167750 (AKT1)
Protein kinases [BR:pviv01001]
 Serine/threonine kinases: AGC group
  AKT/PKB family
   125167750 (AKT1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PH Pkinase_C Kinase-like PH_20 PH_11 Seadorna_VP7
Other DBs
NCBI-GeneID: 125167750
NCBI-ProteinID: XP_047718320
LinkDB
Position
B3:complement(141978734..142000451)
AA seq 480 aa
MNDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVEQRESPLNNFSVAQC
QLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKRQEEEMMDF
RSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKI
LKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLS
RERVFPEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI
KDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL
ILMEELRFPRTLSPEAKSLLSGLLKKDPKQRLGGGADDAKEIMQHRFFASIVWQDVYEKK
LSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQGDSVEGEDSERRPHFPQFSYSASGTA
NT seq 1443 nt   +upstreamnt  +downstreamnt
atgaacgacgtggccatcgtgaaggagggttggctgcacaagagaggggaatacatcaag
acctggaggccccggtacttcctcctcaagaatgacggcaccttcatcggctacaaggag
cggccacaggacgtggagcagagagagtccccgctcaacaacttctctgtggcgcagtgt
cagctgatgaagacggagcggcccaggcccaacaccttcatcatccgctgcctgcagtgg
accacggtcatcgagcgcaccttccacgtggagacccccgaggagcgggaggagtggacc
accgccatccagacggtggccgacgggctcaagaggcaggaggaggaaatgatggacttc
cggtcgggctcgcccagcgacaactcgggggccgaggagatggaggtgtccctggccaag
cccaagcaccgcgtgaccatgaacgagtttgagtacctgaagctgctgggcaaaggcacg
tttgggaaggtgatcctggtgaaggagaaggccacgggccgctactatgccatgaagatc
ctcaagaaggaggtcatcgtggccaaggatgaggtggcccacacgctcacagagaaccgc
gttctccagaactctcggcaccctttcctgacggccctgaagtactccttccagacccac
gaccgtctctgcttcgtcatggagtatgccaacgggggcgagctcttcttccacttgtcc
cgggagcgggtcttccccgaggaccgtgcgcgcttctacggcgccgagatcgtgtccgcg
ctggactacctgcactccgagaagaacgtggtctaccgcgacctcaagctggagaacctc
atgctggacaaggacgggcacatcaagatcaccgacttcggcctgtgcaaggagggcatc
aaggacggcgccaccatgaagaccttctgtgggacgcccgagtacctggcccccgaggtg
ctggaggacaacgactacggccgcgcggtcgactggtgggggctgggcgtggtcatgtac
gagatgatgtgcggccgcctgcccttctataaccaggaccacgagaagctcttcgagctc
atcctcatggaggagctccgcttcccgcgcacgctcagccccgaggccaagtccctgctg
tcggggctgctcaagaaggaccctaagcagaggctgggagggggcgccgacgacgccaag
gagatcatgcagcaccgctttttcgccagcatcgtgtggcaggacgtgtacgagaagaag
ctcagtccgcccttcaagccccaggtcacctcagagacggacaccaggtattttgatgag
gagttcacggcccagatgatcaccatcacgccccccgaccaaggcgacagcgtggagggc
gaggacagcgagcggaggccccacttcccacagttctcctactccgccagcggcacggcc
tga

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