Prionailurus viverrinus (fishing cat): 125172914
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Entry
125172914 CDS
T09889
Symbol
ATIC
Name
(RefSeq) bifunctional purine biosynthesis protein ATIC
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
pviv
Prionailurus viverrinus (fishing cat)
Pathway
pviv00230
Purine metabolism
pviv00670
One carbon pool by folate
pviv01100
Metabolic pathways
pviv01523
Antifolate resistance
Module
pviv_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
pviv00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
125172914 (ATIC)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
125172914 (ATIC)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
125172914 (ATIC)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
pviv04147
]
125172914 (ATIC)
Enzymes [BR:
pviv01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
125172914 (ATIC)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
125172914 (ATIC)
Exosome [BR:
pviv04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
125172914 (ATIC)
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GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Motif
Other DBs
NCBI-GeneID:
125172914
NCBI-ProteinID:
XP_047727508
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Position
C1:complement(16692459..16720931)
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AA seq
592 aa
AA seq
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MAPGQLALFSVSDKTGLVEFARNLTSVGLNLIASGGTAKALRDAGLAVRDVSELTGFPEM
LGGRVKTLHPAVHAGILARNIPEDNADMARLDFDLIRVVVCNLYPFVKTVASPDVTVEQA
VEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVAVCTEMQNSDSKDTSLETRRQLALKAFT
HTAQYDEAISDYFRKQYSKGISQMPLRYGMNPHQTPAQLYTLKPKLPITVLNGAPGFINL
CDALNAWQLVKELREALDLPAAASFKHVSPAGAAVGIPLSEDEARVCMVYDLYETLTPIS
TAYARARGADRMSSFGDFIALSDICDVPTAKIISREVSDGIVAPGYEDEALKILSKKKNG
SYCVLQMDPSYSPDENEVRTLFGLRLSQKRNNGVIDKSLFSSVVTKNKDLPESALRDLIV
ATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKT
GVKRAEISNAIDQYVTGTIGEDEDLVKWKALFEEVPELLTEAEKKEWVDKLNEVSISSDA
FFPFRDNVDRAKRSGVAYIAAPSGSAADRVVIEACDELGIILAHTNLRLFHH
NT seq
1779 nt
NT seq
+upstream
nt +downstream
nt
atggcacccggccagctcgccttatttagtgtctctgacaaaacgggcctcgtggaattt
gccagaaacctaacttctgttggtttgaatttgatcgcttctggagggactgcaaaagct
ctcagggatgcaggtctggcagtcagagatgtctccgagctgacgggatttcctgaaatg
ttaggggggcgtgtgaaaaccttgcatcctgcagtccatgctggaatcttggctcgtaat
atcccagaagataatgctgacatggctagacttgattttgatcttatcagggttgtcgtc
tgtaatctgtatccctttgtgaagacagtggcttctccagatgtaactgttgaacaggct
gttgagcagattgatattggtggagtaaccctcctgagagcagcagccaaaaaccacgct
cgagtaacagtagtatgtgaacctgaggactatgtggccgtttgcacagagatgcagaac
tccgacagtaaagacacctccttggagactagacgccagttagccttgaaggctttcact
catacagcacaatatgatgaagcgatttcagattacttcaggaaacagtatagtaaagga
atatctcagatgcccttgaggtatggaatgaatcctcaccaaactcctgcccagttatac
acgctgaagcccaagcttcccatcacagttctaaatggagcccctggatttataaacttg
tgtgatgctttgaatgcctggcagctggtgaaggaactcagagaagctttagaccttcct
gctgctgcctctttcaaacatgtcagcccagcaggtgctgctgttggaattccactaagt
gaagatgaggccagagtctgcatggtctatgatctgtatgaaacacttacacccatatca
actgcgtatgcaagagcaagaggggctgataggatgtcttcatttggtgactttatcgca
ttatctgatatttgtgatgtccctactgccaaaattatctccagagaggtatctgatggt
atcgtcgccccaggatatgaagatgaagctttgaaaatactctctaaaaagaaaaacggg
agctactgtgttcttcagatggacccgtcttacagtccagatgaaaacgaagttcgaact
ctctttggtcttcgtttaagtcagaagagaaataatggtgtcattgacaagtcattgttt
agcagtgttgtgaccaagaataaagatttgccagagtctgcgctcagagacctcattgta
gccaccattgctgtgaagtacacgcagtctaactccgtgtgctatgccaagaatggtcag
gttattggcattggagcaggacagcagtctcgaatacactgcacacgccttgcaggggat
aaggcgaactactggtggcttagacatcatccacaagtgctttcaatgaagtttaaaact
ggagtgaagagagcagaaatctccaatgccattgatcagtatgttactggaaccattggc
gaggatgaagatttggtaaagtggaaggcattgtttgaggaagtccctgaactgctaact
gaagcagagaagaaagaatgggttgacaaacttaatgaagtttctatcagctctgatgcc
ttctttcctttcagagataacgtagacagagctaaaaggagcggcgtggcatacatcgct
gctccttctggttctgctgccgacagagttgtgatagaggcttgtgatgaactgggaata
attctcgctcatacgaatcttcggctctttcatcactga
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