Prionailurus viverrinus (fishing cat): 125173198 Help Entry 125173198         CDS       T09889                                  Symbol JAK1 Name (RefSeq) tyrosine-protein kinase JAK1   KO K11217   Janus kinase 1 [EC:2.7.10.2] Organism pviv  Prionailurus viverrinus (fishing cat) Pathway pviv01521   EGFR tyrosine kinase inhibitor resistance pviv04151   PI3K-Akt signaling pathway pviv04217   Necroptosis pviv04380   Osteoclast differentiation pviv04550   Signaling pathways regulating pluripotency of stem cells pviv04620   Toll-like receptor signaling pathway pviv04621   NOD-like receptor signaling pathway pviv04630   JAK-STAT signaling pathway pviv04658   Th1 and Th2 cell differentiation pviv04659   Th17 cell differentiation pviv05140   Leishmaniasis pviv05145   Toxoplasmosis pviv05152   Tuberculosis pviv05160   Hepatitis C pviv05161   Hepatitis B pviv05162   Measles pviv05163   Human cytomegalovirus infection pviv05164   Influenza A pviv05165   Human papillomavirus infection pviv05166   Human T-cell leukemia virus 1 infection pviv05167   Kaposi sarcoma-associated herpesvirus infection pviv05168   Herpes simplex virus 1 infection pviv05169   Epstein-Barr virus infection pviv05171   Coronavirus disease - COVID-19 pviv05200   Pathways in cancer pviv05203   Viral carcinogenesis pviv05212   Pancreatic cancer pviv05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:pviv00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     125173198 (JAK1)    04151 PI3K-Akt signaling pathway     125173198 (JAK1)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     125173198 (JAK1)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     125173198 (JAK1)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     125173198 (JAK1)    04621 NOD-like receptor signaling pathway     125173198 (JAK1)    04658 Th1 and Th2 cell differentiation     125173198 (JAK1)    04659 Th17 cell differentiation     125173198 (JAK1)   09158 Development and regeneration    04380 Osteoclast differentiation     125173198 (JAK1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     125173198 (JAK1)    05203 Viral carcinogenesis     125173198 (JAK1)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     125173198 (JAK1)   09162 Cancer: specific types    05212 Pancreatic cancer     125173198 (JAK1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     125173198 (JAK1)    05161 Hepatitis B     125173198 (JAK1)    05160 Hepatitis C     125173198 (JAK1)    05171 Coronavirus disease - COVID-19     125173198 (JAK1)    05164 Influenza A     125173198 (JAK1)    05162 Measles     125173198 (JAK1)    05168 Herpes simplex virus 1 infection     125173198 (JAK1)    05163 Human cytomegalovirus infection     125173198 (JAK1)    05167 Kaposi sarcoma-associated herpesvirus infection     125173198 (JAK1)    05169 Epstein-Barr virus infection     125173198 (JAK1)    05165 Human papillomavirus infection     125173198 (JAK1)   09171 Infectious disease: bacterial    05152 Tuberculosis     125173198 (JAK1)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     125173198 (JAK1)    05140 Leishmaniasis     125173198 (JAK1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     125173198 (JAK1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:pviv01001]     125173198 (JAK1) Enzymes [BR:pviv01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      125173198 (JAK1) Protein kinases [BR:pviv01001]  Non-receptor tyrosine kinases   JAK family [OT]    125173198 (JAK1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase Jak1_Phl FERM_F2 SH2_1 FERM_F1 ABC1 SH2 RIO1 FERM_C_FAK1 Endonuclea_NS_2 Motif Other DBs NCBI-GeneID:  125173198 NCBI-ProteinID:  XP_047728058 LinkDB All DBs Position C1:160752950..161007020 Genome browser AA seq 1156 aa AA seqDB search MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVLFYLSDREPLRLGSGEYTAEEL CIRAAQECCISPLCHNLFALYDENTKLWYAPNRTITVDDKTSLRLHYRMRFYFTNWHGTN DNEQSVWRHSPKKQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN WFHPDDSGNILYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKWKKLENKHKKDEEKNKIRE EWNNFSYFPEITHIVIKECVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAHH YLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVTC FEKSEVVGSQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMNHLKKQILRTDNISFVLKR CCQPKPREISNLLVATKKAQEWQPVYSMSQLSFDRILKKDIVQGEHLGRGTRTHIYSGTL LDYKDDEGTSEEKRIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDVE NIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLLL AREGIDSEFGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGTT LWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAIM RDINKLEEQNPDIVSERKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTG EQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPSG SLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDF GLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSDS SPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPTNRTTF QNLIKGFEALLEALLK NT seq 3471 nt NT seq  +upstreamnt  +downstreamnt atgcagtatctaaatataaaagaggactgcaatgccatggctttctgtgctaaaatgagg agctccaagaagacggaggtgaatctggaggcccccgaaccaggggtggaagtgctcttc tatctgtccgatagggagccgctccggctgggcagcggggagtacacggcagaggagctg tgcatcagggcggcgcaggaatgctgtatctctcctctgtgtcacaacctttttgccctg tatgatgagaacaccaagctttggtacgctccgaatcgcacgatcacagttgatgacaag acatcactccggctccactaccggatgaggttctatttcaccaactggcatgggaccaat gataatgagcagtctgtatggcgacattctccgaagaagcagaaaaatggctacgagaaa aaaaaagttccagatgcaacccctctccttgacgccagctccctggagtatctgtttgct cagggacaatatgatttggtcaaatgcctggctcccattcgagaccccaagaccgagcag gatggacacgatattgagaacgagtgtctgggaatggctgtcctggccatctcccactac gccatgatgaagaagatgcaattgccagaactgcccaaggacatcagctacaagcgatat atcccagaaacattgaataagtccatcaggcagaggaatcttctcaccaggatgcggata aataacgttttcaaggatttcctaaaggaatttaacaacaagaccatctgtgacagcagt gtatctactcatgacctgaaggtgaaatacctggcgaccttggagactttgacaaaacat tatggtgctgaaatatttgagacttccatgttactgatttcgtcagaaaatgagatgaat tggtttcatccagatgacagtggaaacattctctatgaagtgatggtaactggaaatctt ggaatccagtggagacagaaaccaaatgttgttcctgttgaaaaggaaaaaaacaaactg aaatggaaaaagctggaaaataaacacaagaaggatgaggagaaaaacaaaatccgggaa gagtggaacaatttttcttacttccctgaaatcactcacattgtaataaaggagtgtgtg gtcagcatcaataagcaggacaataaaaaaatggaactgaagctttcgtcccacgaggag gccttgtcctttgtgtccctggtagacggctacttccggctcacagcggatgcccatcat tacctctgcactgatgtggctcccccactgattgtccacaacatacagaatggctgtcac ggtcccatctgcacagaatatgccatcaataagttgcggcaagaaggaagtgaggaggga atgtatgtgctgaggtggagctgtaccgactttgacaatatcctcatgactgtcacctgc tttgaaaaatctgaggtggtgggtagccagaaacagttcaagaacttccagatcgaggtg cagaagggccgttacagcctgcatggctcggaccgcagcttccccagcctgggggacctc atgaaccacctcaagaaacagatcctgcggacggacaacatcagctttgtgctgaaacgc tgctgccagcccaagccccgagagatctccaatttgctggtggctactaagaaagcccag gagtggcagcctgtctactctatgagccagctgagttttgaccggatcctcaagaaagat atcgtgcaaggcgagcaccttgggagaggcacgcggacgcatatctactctggaaccctt ctggattacaaagatgacgaaggaacttccgaagaaaagagaataaaagtgatcctcaaa gtcttagaccccagccacagggacatttctctggccttctttgaggcagccagcatgatg aggcaggtctcccacaaacacatcgtgtacctctatggcgtctgtgtccgagatgtggaa aatatcatggtggaggagtttgtggagggggggcccctggatctcttcatgcaccggaaa agcgatgtcctcaccacaccgtggaagtttaaagttgccaaacagctggctagtgccttg agttacttggaggataaagacctggtccacggaaatgtgtgcactaaaaacctcctcttg gcccgtgagggcatcgacagtgagttcggcccgttcatcaagctcagtgaccccggcatc cccatcaccgtgctgtccaggcaagagtgcatagaacgaatcccgtggattgctcccgag tgtgttgaagactccaagaacctgagtgtggccgctgacaaatggagctttggaaccaca ctctgggaaatctgctataatggcgagatccctctgaaagacaagacactgattgagaaa gagcgattctatgaaagccggtgccggccagtgacaccatcttgtaaggagctggctgac ctcatgacccgctgcatgaactatgaccccaaccagagacccttcttccgagccatcatg agagacatcaataaactggaggagcagaatccagacattgtttcggaacgaaagccggca accgaagtggatcccacacattttgaaaagcggttcttgaagagaatccgtgacttggga gagggccactttgggaaggttgagctctgcagatacgaccctgagggtgacaataccggg gagcaggtggctgtcaaatccctgaagcctgagagtggaggtaaccacatagctgatctg aagaaggaaattgaaatcttaaggaacctctatcatgagaacattgtgaagtacaaaggc atctgtacagaagacggaggaaatggtattaagctcatcatggagtttctaccttcagga agccttaaggaatatcttccaaagaataagaacaaaattaacctcaaacaacagttaaaa tatgctgttcagatttgtaaggggatggactacttggggtctcggcagtacgttcaccgg gacttagcagcaagaaatgtcctcgttgagagtgagcaccaagtgaaaattggagacttc ggtttaaccaaagccattgaaaccgacaaagagtactacacagtcaaggatgatcgggac agccctgtgttttggtatgctccagaatgtttaattcagtgtaaattttatatcgcctct gacgtctggtcgtttggagtgactctgcatgagctgctcacttactgtgactccgattct agccccatggcattgttcctgaaaatgataggcccaacgcatggccagatgacagtcaca agacttgtgaacacgttaaaagaaggaaaacgtttgccctgtccacctaactgcccagat gaggtttatcaactcatgagaaagtgctgggaattccaaccaactaataggacaactttt cagaacctaattaaaggatttgaagcacttttagaagcacttttaaaataa

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