Penaeus vannamei (Pacific white shrimp): 113815056 Help Entry 113815056         CDS       T06111                                  Symbol RyR Name (RefSeq) ryanodine receptor   KO K04962   ryanodine receptor 2 Organism pvm  Penaeus vannamei (Pacific white shrimp) Brite KEGG Orthology (KO) [BR:pvm00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:pvm04040]     113815056 (RyR)    04990 Domain-containing proteins not elsewhere classified [BR:pvm04990]     113815056 (RyR) Ion channels [BR:pvm04040]  Voltage-gated cation channels   Ryanodine receptor    113815056 (RyR) Domain-containing proteins not elsewhere classified [BR:pvm04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    113815056 (RyR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR Ins145_P3_rec SPRY MIR RR_TM4-6 RIH_assoc Ion_trans EF-hand_7 EF-hand_5 EF-hand_1 EF-hand_6 SPARC_Ca_bdg UreE_C Motif Other DBs NCBI-GeneID:  113815056 NCBI-ProteinID:  XP_069998985 LinkDB All DBs Position 30:complement(7255517..7434159) Genome browser AA seq 5060 aa AA seqDB search MADSEGSSEQDDVSFLRTEDMVCLSCTATGERVCLAAEGFGNRTCFLENIADKNNPPDLS QGVFVIEQALSVRALQELVTAAANEEENAGVGKGTGSGHRTLLYGNAVLLRHQNSNMYLA CLSTSSSKDKLAFDVGLQEHSKGESCWWTIHPASKQRSEGEKVRVGDDLILVSVATERYL QATREDEQSIVNASFHVTHWSVAPFGTGLSRLKFVACVFGGEVLRFFHGGDECLSIPSTW SDQPGQNIVVYEGGSVTSQARSLWRLELARTKWSGGYINWFHPMRIRHITTGRYLGINEN NDLVLLHRDEATLAATSFYLREEKDDNKVILEDKDLEVIGTPLIKYGDSTVIVQHVDTGL WLSYRAFEIKKKGVGKVEVKQGTLHEEGKMDDGLVFYRSQEEESRTARVIRKCSHLFTIF IKGLDNIQASRRHSILLRTVNLKEMISCLEDLINYFAYPEEELEHEERQVALRALRNRQD LFQEEGILNLILDAIDKITVITSQGYMVALAGEEAGQDWEVISGYLYQLLAAVIKGNHTN CSQFANSHRLNWLFSRLGSAGEGTGMLDVLHCVLIDSPEALNVMKEEHIKVIIALLEKYG RDPKVLDVLCSLCVGNGTAVRSSQNNICDYLLPGRNLLLQTQLVDHVSSARPNIFVGHVE GSAMYQRWYYELTLDHIEQVSHLSPHLRLGWANTKGYVSYPGGGEKWGGNGVGDDLYSFG FDGSYLWTGGRYTLVNPQDSEPLIKKGDVVGCALDLTVPIITFYLNGRQVNGAFTGFNLD GMFFPVVSASSKLSVRFLLGGEHGRLKYPPPDGHSPVSECLQPFQTLSIDPCFYFGEQHK GTLAGPLLVEDDKVFVPKPVDTSTIQLPGYIEQVRDKLAENIHEMWAMNKIEQGWTYSER RDDLRLHHPCLTSFEKLPISEKRYDSTLALQTLKTVLALGYHITLDKPPSRIRSVRLPND PFLQSNGYKPQPLDLSQVSLTPKLEELVDQLAENTHNIWARERILQDWTYGLNEDPDMRR SPHLVSYANVDEAIKKANRDTASETIRTLLVYGYILEPPTGDQAEGAGDAEDTSRRATLH RTYRLEKTNAVTAGKWYFELEVLTSGPMRVGWLEVGSPPGAELGSDDRSWAFDGFHHLKH HNAISEAYGHRIQAGDVVGVMLDLHDRTISFSLNGELMMDASGSETAFCDVQGDAFVPAC TLGVGQKAHFVFGQDINQLKFFTTYGLQESYEPFCVNMERPVTFWYTKDQPIFENNDDLT ESTIDVTRIPAGSDTPPCLKIASKMFEQCEKANWEFLRLSLPVVCDQEFIDEEEKARRWQ EVRIRQNRIQSGDLQGPAHFESSLVDTGFSMSDIKELHYNEEGVEADEGIVRKEAAVTPE KAASLTPEVNGVTEEGAPEPAERKKRGKSPFRFFSKKREASAERGRSKGRTPEPTSNSLE PQRPAKKNRSPSVRLAQGEAKLVPPAIPERQGASDEAREEQLFDAGCLKLMNEYFYGVRI FPGQDPAHVYIGWVTTQYHIHDTAFDQNKVRSVIVQEYTEEGHIKSAVERHSCYMFRADE LHAEVSSDVGGKGTSQGMFIGCFIDTSTGFITLQCDGKDTRHKYRMEPGTKLFPGVFLEP TSKEVLQIELGRTATTLPLSAAVLQNSEKHVTPQMPPRLRVQILKPHQWSRVPNTSLRIH ALKLSDIRGWSMLAEDSVPMLALHIPEEDRCIDILELIEYDKLLAFHTQTLALYCAVCYQ SNYRAAHTLCSHVDQRQLLYAMQSEYMSGPLRMGFYNLVIALHLESFANTMEVTQNEFIV PLSNDLKEIYQEEGMGNSMSATHTESVRPVMTMSDISNQINADNISIHSMIHVSCGTPRP SANIETIKGLSSPYFPLDVAREFVMASLNEAVNTNQVHNRDPIGGSNENLFVPLLKLVDK LLLVGVLQDEDITRLLIMIDPQTWDAEFDPEGKDENRKGIVQMEIAEGVKLQLCYVLHHL LDLQKRHRVENIIAFAQDYVGDIQQDQLRRYIEIKQSDLPSSVAAKKTREFRCPPREQMN AILGFKTLTDEELEESPCREELRGVLIDFHDLLMVKAKIPGGEEEEGEAEESPEPESKGV MSKVLAVLSGNKEEAPEPPAKEPIVLDSADKFKKVLVNTIVRWASETFIENPILIREMFS LLLRQYNSIGELMTALEKTYVISSNTKKDVETLWLCLSKVRALLPVQMSQEEEELMRELL WTLVNNHIFFQHPDLIRILRVHENVMAVMMNTLGRRAQAQNETQAVEGEAAQAKEKDTSH EMVVACCKFLCYFCRTSRQNQKAMFDHLPFLLDNSNILLSRPSLRGTTPLDVAYSSLMDN TELALALREHHLEKIAVYLSRCGLQSNSDLVERGYPDLGWDPVEGERYLDFLRFCVWVGG ESVEENANLVIRLLIRRPECLGPALRGEGEGLLCAIIDANKMSERIALQRLGAEAEGVVP IEHPMPAGDDDEDYVDTGAAILNFYCTLVDLMGRCAPEANVIAQGKNDSLRARAILRSLV PLEDLQGVLSLRFTLSNTSDEGRSDMPPGLIPAHKQSVVLFLERVYGMNNKDLFFSLLED AFLPDLRAATALDKSDGSESEMGLALNRYIGNSILPALISHSSFYAEAEAHAPLLDATLH TVYRLSKCKILTKGQREAVSDFLVALTREMQPAALLPLLRKLTIDVSKLSEYTTVALRLL TLHYERCGKYYGSSSNTPGTASEEEKRLTMMLFTNIFDSLAKMEYDPDLFGKALPCLSAI GCSLPPDYSLTHGYDDELYNTASCAEGPYKPAPISTEEVQLDQDIVDLINKFSEHYHDAW ASRKLESGWTYGEAYSIEDKMHPRLKPYSMLSDYERERYREPVREAIKALLALSWNIEYE SMENTSAGREQLHRQDTSDLYNYNPQPVDMTNLTLSREMQNMAERLAENAHDIWAKRKVE ELEACGGGLHPQMVPYDMLTEKEKRKDRFRSIELLKYLQFMGYRLSRSGAVEDSGAGSAG AVERRFAYSLLEKLLQYLDCAAINMKLLKPSANLSRRSSFKTSTKDVKFFSKVVLPLMEK YFSTNRNYFLTVAQTSTMVGAASLKEKEMVASLFCKLANLMRLKMVCFGSDTKVTVKCLQ VIVRSVDAKTLAKSLPEFIRTSMLTFFNNAAVDLEMCIHCLQEGKYAYIRGTHLKTSASL NYVQTVLLPVLTSLFDHTAACEFGQDLLLDEIQVACYKILAALYQLGTDLSLDGNRTFMK KELDRHRPAIGNCLGAFAGTFPVAFLEPLMNKNNPWSIHNRIADQSLEAQEIIVKMETAM PTLEAVMKEVEKFVDDESKHTEFPFIIDVILPMLCSYLPFWWNQGPDNVNPSEGNHVSMV TCEHMNQLLRLVLRLIMFNVGVENAPWMTRIAGYTQQIIINSSEELLKDAYLPLAERVHK RTEYMFNKEENLRSFLKSTTEDTSQVESQLQEEWQLLTRDIYAFYPLLIKYVDQQRNHWL KHGVPEAEDVYNRVSQIFHIWSNSQYFRREETNFISQNEIDNMTLIMPTASSRNRAAVMP EASAGGGKKKKRRADGKKMSKEKELASSLMVACLKRLLPVGLNLFAGREQELVQHCKEKF LAKVPESEILVFAKTQLTLPDKIDPSDAMNWQHTLYSRLGGGRVPREDDEEKKLVPSVDE TVDNIVAMAKVLYGLHIIDHPQSSKEVWRSVVSIQRKRAVIACFRQTSLHMMPRHRAVNL FLRTYREYWLSDENVGQEVVIEDLTQSFEEAESKKKEAEEDDGKPDQLTQLVTTFSRKAT TEHTGVLAEDPLYMSYADIMAKSCGEEEEEGEEEGGGEEEGGNEDPAAALNEQELEKQKL LFHQARLSNRGVSEMVLLHVSAARGQPSDMVMNTLKLGISILRGGNVDVQAAMLNYLKEK KDAAFFLSIAGLMNSCSVLDLDAFERNTKAEGLGVGADGCAGEKNMHDAEFTCALFRFIQ LTCEGHNLDWQNYLRTQAGNTTTVNVINCTVDYLLRLQESIMDFYWHYSSKEIIDPAGKA NFFKAIGVASQVFNTLTEVIQGPCVGNQQTLAHSRLWDAVGGFLFLFANMQDKLSKHSSQ VDLLKDLLNLQKDMVIMMLSMLEGNVVNGTIGKQMVDTLVESASNVELILRYFDMFLKLR DLTSSTTFQELDTNKDGTVTPIEFKEKMEQQKNYTTEEINFLLMCCDTNHDGKIDYVEFT ERFHNPAKEIGFNLAVLLTNLSEHMPNEPRLARFLETAGSVLNYFEPFLGRIEIMGSSKR IERVYFEIKEENIDQWEKPQIKDSKRSFFYAIVTEGDKEKLEAFVNFCEDAIFEMQHATA LMEEEDDAMSKKSNADGLKYLSEDEEEKTGMDLIKSKIGGVKDQMLEGLSVFAPSNLKKK IKEIKQMSSTELAVGFCRLLFLIMYHSAFGVVYVLRKVWQALMGLMQGPPAEKAEEKEEK AGPLVPLAVPALPEIPEGDAAPPAEEGKKPEGEQLSLEAADLTQEEKVKPILDALADLKE DITAEEAISAAKLAEKKEVETAQAAAMEEAEVVESSAAAEPPPVAQVDLSGYNKRAVSFL ARNFYNLKYAALVLAFCINFILLFFKATVVEIEEEEGEDTDVNNPFAFGSGDLLGSGDEA VLGDDAADELGSGNFTLGEDDDEDEEDEEEEEWIHMDDRYFYLSHILRLLTTTHSIVALC MLLAYYHLKIPLVIFKREKDVARRLEFDGIYVAEQPEDDDIKAHWDKLVISAKSFPNNYW DKFVKKKVREKYSETYDFDAISNLLGMETTMSFKQEEVPTGIIGYLSSVDWKYQIWKAGV TITDNQFLYNLWYLTFSLLGNINYFFFAAHLLDVAVSIPSLKTILQSVTHNGKQLILTCM LLTIIVYCYTVIAFNFFRKFYVSEEDDVVDQKCHDMLTCFVFHLYKGVRAGGGIGDEIEA PDGDEYEFYRIVFDITFFFFIIVILLAIIQGLIIDAFGELRDQLESVKENLESNCFICGI GNDYFDAVPHGFDMHTQKEHNLANYMFFLMHLINKDETEYTGQETYVWNMYQERCWDFFP VGDCFRKQYEEELSGGASAS NT seq 15183 nt NT seq  +upstreamnt  +downstreamnt atggcggacagtgaagggtcttccgaacaagatgatgtttcgttcctccgtacggaggac atggtgtgcctgtcctgcacggccaccggcgagagggtatgcctggctgcagaaggcttc ggcaaccggacatgcttccttgaaaacattgcagataagaataacccgcccgacctctcc caaggcgtcttcgtgatcgagcaggcgctgtcggtcagggctcttcaggaactcgtcaca gcggcggccaacgaagaggagaatgcgggcgttggcaaaggcacaggttcgggacacagg acgctgctctatggcaatgccgtcctcctcaggcaccagaactccaacatgtacctggcc tgcctctccaccagctcttccaaggacaagctggccttcgacgtgggtctgcaggaacac tccaagggagagtcgtgttggtggaccatccacccggccagcaagcagaggtctgagggc gagaaggttcgagtcggtgacgacctcattcttgtgtctgttgccaccgagcgatatctg caagcaacacgcgaagacgagcagagcatcgtcaacgcctccttccacgtcacccactgg tccgtcgcgccctttggcaccggcctctccagactcaagtttgtggcctgtgtattcggc ggagaggtccttcggttcttccacggtggtgacgagtgcctctctattccttccacgtgg tccgatcaacccgggcagaacatcgtcgtatatgaaggtggctccgtgacctcccaagct aggtccctctggcgcctggagctcgcccgcaccaagtggtcaggcggctacatcaactgg ttccatcccatgcgaatcaggcacatcaccaccggcagatacctgggcatcaatgagaac aatgacctcgtcctcttgcacagggacgaagccacactcgctgccacgtccttctacctg cgcgaggaaaaggacgacaacaaagtgatcctcgaggacaaggacttggaggtgattggc actccactcatcaagtacggcgactccactgtcatcgtgcagcacgtggataccggtctg tggctctcgtacagggccttcgagatcaagaagaagggcgtgggcaaagtcgaggtgaag cagggcacactccacgaagagggcaagatggacgacggcctggtcttctacaggagtcaa gaggaagagtcccgcaccgctcgcgttatcaggaagtgctcgcatctcttcacgatcttt atcaagggtttggataacatccaggcttctcgccgtcactccatcctcctaagaactgtc aacctcaaggaaatgatcagctgtttggaagatctcatcaactacttcgcatatcccgaa gaagaacttgaacacgaggaacggcaggtggctctccgtgctctcaggaaccgccaggac ctgttccaagaggagggcatcctcaaccttatcttagacgccatcgacaagatcacagtc atcacgtcccagggctacatggtggcgctggcgggagaggaagctggccaggactgggag gtcatctcgggatacctgtaccagctgctggcggcggtgattaagggtaaccacaccaac tgctcccagttcgcaaacagccaccgcctcaactggctgttctcccgtctgggctccgct ggcgagggcaccggcatgctggatgtgttgcactgcgtcctcatcgactctccagaagct ctcaatgtcatgaaggaagaacatatcaaggtcatcatcgccctgttagaaaagtacggc cgcgaccccaaggtactggacgtcctctgttctctgtgcgtgggtaacggaacagctgtt aggtcttcgcagaataacatctgtgattacctgcttccgggtcgcaatctcctgctgcag acacagcttgttgaccatgtatccagcgcccgccccaacatcttcgtgggccacgtcgag ggctcggccatgtaccagaggtggtactacgagctcaccctggatcacatcgagcaggtg tcgcatctgtcgcctcacctgcgcctcggctgggccaacaccaagggctacgtcagctat cccggaggaggcgagaagtggggaggcaatggcgtgggcgacgacctctactccttcggc ttcgacggctcgtacctctggactggcgggaggtacacgctggtcaaccctcaggactcg gagcccctaatcaagaaaggtgacgtggtcggctgtgccctggatctcaccgtgccaatc attaccttttacctaaatggacggcaggttaatggcgctttcacaggttttaatcttgac ggcatgtttttccccgtcgtgtcggcgtcttccaagctcagcgtgaggttcttgctgggc ggtgaacacggtcgcctcaagtacccccctcctgatggacactctcccgtctccgagtgc cttcagcccttccagacgctgtcgatcgacccctgcttctacttcggcgagcagcacaag ggcactctcgcggggcctctccttgtggaagacgacaaggtgttcgtgccgaagcctgtc gacacttcaacgatccaactccccggctacatcgaacaagtacgagacaagctggccgag aacatccacgagatgtgggccatgaacaagattgaacagggctggacttactcggagcgc agggacgacctccgcctccaccatccttgcctcacttccttcgagaagcttccgatcagc gagaagcgatacgactccacgctggctctgcagacactcaagaccgtgctggcgctgggg taccacatcaccctggacaagccgcccagccgaatccgctctgtccgactgcccaacgac cccttcctgcagagcaacgggtacaagccgcagcctctcgatctgtcacaggtcagccta accccgaaactggaggagctggtcgaccagctggccgagaacacccacaacatctgggct cgcgaacgtatccttcaggactggacttacggcctgaacgaggaccctgacatgcgccgt tcgccccacctggtcagctacgcgaacgtggacgaggcgatcaagaaggccaacagggac accgcctccgaaaccatcaggacgctcctggtctacggctacatcctggaaccccccacg ggcgaccaggcagaaggcgcaggcgacgccgaagacaccagccgacgtgccaccctacac cgcacctaccgcctggagaagaccaacgcggtgacggcgggcaaatggtacttcgagctg gaggtgctgacgtcgggccccatgcgagtcggctggctggaggtcggaagccctcccgga gccgaactcggatccgacgacaggtcctgggccttcgacgggttccatcacttgaaacac cacaatgccatatcggaggcatatggccaccgtatccaggccggcgatgtggtgggagtc atgctggacctgcatgacagaaccatcagtttctcgctcaacggagaactcatgatggac gcgagcggctccgagacagccttctgcgacgtgcagggcgacgcgttcgtgccggcctgc accctcggcgtcggccagaaggcgcacttcgtcttcggccaggacatcaaccagctcaag ttcttcactacttacggtctccaggagagctacgagcccttctgcgtgaacatggagcgc cccgtgaccttctggtacacgaaggaccagcccatcttcgagaacaacgacgacctcacc gaatccaccatcgacgtgacccgcatccccgccggttccgacactcctccgtgcctcaag atcgcgtccaagatgttcgagcagtgcgagaaggccaactgggagttcctgaggctgtcg ctgcccgtggtgtgcgaccaggagttcatcgatgaggaagagaaggccaggcgatggcag gaggtgaggatccggcagaacaggatccagagcggagaccttcagggccccgcccacttc gagagctccctcgtcgataccggattctctatgtccgacatcaaagagctgcattacaac gaggaaggtgtagaagccgatgaaggaatcgtgcgcaaggaagcagccgtcactccagag aaagccgcctccctgacgcccgaggtgaacggcgtgacggaggagggcgcccctgagccc gccgagagaaagaagcggggcaagtctcccttcaggttcttcagcaagaagcgcgaggcc agtgctgagcgaggtcggagcaagggacgcacccctgagccgacctccaacagcctcgag ccccagcgccccgctaagaagaatcgttctccctccgtcaggctagcgcaaggcgaggcc aagctcgtcccgccagctatcccggagagacagggcgcgagcgacgaggcgcgcgaggaa cagctgttcgacgccggctgcctcaagctcatgaacgagtacttctacggcgtgaggatc ttccccggccaggacccggcgcacgtgtacatcggctgggtcacgacgcagtaccacatc cacgacaccgccttcgaccagaacaaggtgcgctcggtcatcgtgcaggagtacacggag gagggccacatcaagagcgctgtggagcgacacagctgctacatgttccgcgccgacgag ctccacgcagaggtgtcctcagacgtgggcggcaagggcacgtcgcagggcatgttcatc gggtgcttcatcgacacctccacgggcttcatcaccctgcagtgcgacggcaaggacacc cgccacaagtaccgcatggagcccggcaccaaactcttccccggcgtgttcctggagccc accagcaaggaggtgctgcagatcgagctgggacgcacggccaccacgctccccctcagc gccgccgtcctccagaacagcgagaagcacgtcactccccagatgccaccgcgcctcagg gtccagattctgaagccccaccaatggtctcgagtccccaacacgtccctgaggatccac gcactcaagctgtcagatattcgtggctggtccatgctggctgaggactcggtgcccatg ctcgccctccacattcccgaggaggaccggtgcatcgacatcctcgaactcatagagtac gacaaattactcgccttccacacgcagacgttagccctgtactgcgccgtgtgttaccag agcaactacagggccgcccatacattgtgctctcacgtggaccagaggcagctactgtac gccatgcagagcgagtacatgtcgggcccgctcaggatgggcttctacaacctcgtcatt gcattgcatctggagagtttcgcaaatacaatggaggtgacccagaacgagtttatcgtg ccgctgagcaacgacctgaaggagatctatcaggaggagggtatgggcaactccatgtca gccacacacaccgaatccgtccgacctgtcatgaccatgtcagatatctctaaccaaatt aacgccgataacatatctatacactcgatgattcacgtctcatgtggcaccccccgtccc agtgccaacatcgaaacgatcaaaggcctctcgtcaccttacttccctctcgacgtcgcc cgcgagttcgtcatggcttctctcaacgaggccgtcaacacgaaccaggtgcacaacagg gaccccatcggcggctccaacgagaacctcttcgtgccgctgctgaagctggtggacaag ctcctcttggtgggcgttcttcaggacgaggacatcacaagactcctcattatgatcgat cctcagacgtgggacgcagagttcgaccccgagggcaaagacgaaaacaggaagggcatc gtacaaatggagatcgccgagggagtaaagttgcaactgtgctacgtcttgcatcatctt ctggacttgcagaagcgccatcgcgttgaaaacatcatcgcattcgcgcaggattacgtt ggcgatatccagcaagaccagctgcggcgctacatcgagatcaagcagtccgaccttcct tcgtctgtcgcggccaagaagacgcgcgagttccgctgtcctcctcgcgagcagatgaac gctatcctcggcttcaagacgctcactgacgaggagctcgaggagtcgccctgccgggag gagctgaggggtgtcctcattgacttccacgacctccttatggtcaaggctaagatccct ggtggagaggaggaagaaggagaagccgaggaatcaccggaacccgagtcgaagggcgtg atgtcgaaggtccttgccgtcctcagcggaaacaaggaagaggctccagaaccgccggcc aaggaacccatcgtcctcgacagcgccgacaagttcaagaaggtcctggtgaacacgatc gttcgctgggcctccgagaccttcatcgagaaccccattcttatcagggagatgttcagc ctgttactgcgacagtacaacagcatcggggagctgatgacggccctggagaagacctac gtcatcagcagcaacaccaagaaggacgtggagaccctgtggctgtgcctgagtaaagtg cgagctctcctgcccgtccagatgtcccaggaggaggaggagctcatgagggagttgctg tggactctcgtgaacaaccacatcttcttccaacaccccgacctcatccgcatcctccgt gttcacgagaacgtcatggctgttatgatgaacaccctcggacgtcgagctcaggcccag aacgagacccaagccgtcgagggcgaggccgcgcaagccaaggagaaggacacctcgcac gagatggtggtcgcctgctgcaagttcctttgttacttctgccggacgagtcgccagaac cagaaggccatgttcgaccacctgcccttcctgctggataactcgaacatcctgctctcg aggccctccctgcgcggcacgactccgctcgacgtggcctactcctcgctcatggacaac accgagctggcactggctctcagagagcaccacctggagaagatcgccgtctacctgtcc aggtgcggtctccagagcaacagcgacctggtggagcgcgggtacccggatctcggttgg gatcctgtggagggcgagcgctatctcgacttccttcgcttctgcgtgtgggtcggaggc gagagtgtggaggagaacgccaacttggtcatccgtctgctgatccgccggccggagtgc ctgggtcccgcactcaggggtgagggcgaaggcctgctctgcgccatcatcgacgctaat aagatgtctgagcgcatcgcccttcagcgcctgggagccgaggccgagggtgtcgtgccc atcgagcacccaatgcccgcgggagacgacgacgaggactacgtggacaccggcgccgcc atcctcaacttctactgcaccctggtcgacctcatgggccgctgtgccccggaggccaac gtcatcgcccagggcaagaatgacagccttcgcgcccgggctattctccgctccctcgtg cccctggaggacctgcagggcgtcctgtcgctgcgattcacactgtccaacacctccgac gaaggcaggagcgacatgcccccgggtctcatccccgctcacaagcagagcgtcgtgctc ttcctcgagcgtgtctacggcatgaacaacaaggacctcttcttcagcctcctcgaagac gctttcctgcctgacctgagagccgccacagcgctcgataagtccgatggctccgagtcc gagatgggtctcgccctcaaccgctacatcggaaactccatcctgccggcactcatctcg cactccagcttctacgccgaggctgaggcccacgcgcccctgctggatgccacgctccac accgtctataggctctccaagtgcaagatcctgacgaagggccagcgagaggccgtgtcc gacttcctggtggctctgacccgcgagatgcagccggccgccctgctgccgctcctccgc aagctgaccattgacgtctccaagttgtcggagtacaccaccgtcgccctcaggctgctg accctgcactacgagcgctgcggaaagtactacggctcctcctccaacacccctggcacc gcctccgaggaagagaagcgcctgaccatgatgctcttcaccaacatcttcgactccctg gccaagatggagtacgacccagacctgttcggcaaggctctgccatgcctctcagccatc ggttgttccttgccccccgactactcgctcacccacggctacgacgacgagctctacaac accgcctcctgcgccgagggaccctacaagcccgcccccatcagcacggaggaggtgcaa ttggaccaggacatcgtggacctgatcaacaagttcagcgagcactaccacgacgcttgg gcctcacgcaagctggagagcggctggacctatggggaagcctactccattgaggacaag atgcatcccagactcaagccttattctatgctgtccgattacgagcgtgaacgataccgc gagcccgtgagagaagccatcaaggcccttcttgccctcagctggaacatcgagtacgag agcatggagaacacgagcgccggccgagagcaactgcaccgccaggacacctccgatctg tacaactacaacccacaacctgtggacatgaccaacctgacgctgtccagggagatgcag aacatggccgagcgtctggctgagaacgcgcacgacatctgggccaagaggaaggtcgag gagctggaggcctgcggtggcggcctgcaccctcagatggtgccatacgacatgctgacc gagaaggagaagcgaaaggaccgcttccgctccattgagctgctcaaataccttcagttc atgggctacaggctcagcaggagcggcgccgtagaggacagcggtgcaggaagcgcagga gccgtcgagcgtcgcttcgcctacagtctgctcgagaagctactgcagtacctggactgc gcagccatcaacatgaagctgctgaagccctctgctaatctctccaggcgaagctccttc aagacttcgactaaggatgtcaaattcttctcgaaggtcgtgctcccgctgatggagaaa tacttcagcaccaaccgcaattacttcctgacggtggcacagacatcgacgatggtgggt gcggcgtctctcaaggagaaggagatggttgcttccctcttctgcaagctggctaatctc atgcgtctcaagatggtctgcttcggttctgatacaaaggttacggtgaagtgcctgcag gtgatcgtgcgttccgtcgacgccaagacgctggccaagagtctccccgagttcattcgc acgtcgatgctcactttcttcaacaacgcagccgtcgacctggagatgtgcatccactgt cttcaggagggtaaatacgcttacattcgaggtactcacttgaagacgtcggcatctctc aactacgtgcagacagttcttctgccggtgctcacctcgctcttcgatcacacggcagcc tgcgagttcgggcaagatcttctattggacgagatccaagtggcttgctacaagatccta gcggcgctctaccagctgggcaccgacctctctctagatggcaacaggaccttcatgaag aaggaactcgatcgccatcgtccggccatcggcaactgtctcggggccttcgctggaacg ttccctgtggccttcctggagccactcatgaacaagaacaacccctggagcattcacaac cgcattgccgatcagtccctggaggctcaagaaatcatcgtgaagatggagacagccatg ccgaccctggaagccgtcatgaaggaagtggagaagttcgtagacgacgaatccaaacac accgagttcccattcatcatcgacgtcatcctgcccatgttgtgctcctacctgcccttc tggtggaatcagggaccggataacgtgaatccatctgagggcaaccacgtgtctatggtg acgtgtgagcacatgaaccagctcctgcgcctggtgctgcgtctcatcatgttcaacgtg ggtgtggagaacgccccttggatgacccgcatcgccggctacacccagcagatcatcatc aactccagcgaggaactgctcaaggacgcttacctccccctggccgagagggtccacaag cgaacggagtacatgttcaacaaggaggagaatctcaggagtttcctgaagtccactacc gaggatacaagtcaggtcgagagccaactccaagaggaatggcaactgctcacgagggac atctatgccttctatcctctgcttatcaagtacgtcgaccagcagaggaaccactggctc aagcacggcgtgccagaggctgaggatgtatacaaccgcgtctcacagatcttccatatc tggtcaaactcacagtacttccgacgagaggagacgaacttcatcagccagaacgaaatc gacaacatgaccctgatcatgcccacggcctcctcccgcaaccgcgccgccgtcatgccc gaggcgtcggctggaggcggcaagaagaagaagaggcgcgccgacggcaagaagatgagc aaggagaaggagctcgcgtcctctctcatggtggcttgtctgaagcgtctcctgccggtg ggtctcaacctcttcgcaggtcgggaacaggagcttgtgcaacactgcaaagagaagttc cttgcgaaagtacctgaatccgagatcttggtgttcgccaagactcagctgacgctgccc gacaagatcgacccgtctgacgccatgaactggcagcacacgttatactcgcgtctcgga ggcggccgcgtcccgagggaggacgacgaggagaagaagctggtcccgagcgtagacgag actgtcgataacatcgtcgccatggctaaggtcctctacggcctccacatcatcgaccac cctcagtcgtccaaggaagtctggcgttcagtcgtgtccatccaacgcaagcgagccgtc atcgcctgcttcagacagacgtccctccacatgatgccaaggcatcgcgccgtcaatctg ttcctccgcacctaccgggagtactggctctcggacgagaacgtgggccaggaggttgtc atcgaggatctgacgcaatccttcgaagaggccgagagcaagaagaaggaagcggaggag gacgacggcaagcccgatcagctgacgcagctcgtcacgaccttcagcaggaaagcgacg accgagcacactggcgtcttggccgaggacccgctctatatgtcttatgccgacatcatg gctaagtcatgcggcgaagaagaagaggaaggagaggaagaaggaggaggagaggaagaa ggaggcaatgaggacccagcagctgctcttaatgaacaagagttggagaaacagaaactg ctgttccaccaggcgagactgtccaacagaggcgtcagcgagatggtgttgctgcacgtc tctgccgccagaggtcagcccagcgacatggtcatgaacacactcaagttgggcatctcc attctgcgcggtggcaacgtggacgtccaggcggctatgctgaactacctgaaggagaag aaggacgccgcgttcttcctgtccatcgccggcctcatgaattcctgctccgtgctcgac ctggacgccttcgagcgcaacacgaaggcagagggcctgggcgtgggcgccgacgggtgc gcgggcgagaagaacatgcacgacgccgagttcacctgcgccctcttccgcttcatccaa ctcacctgtgaaggccacaacctcgactggcagaactacctgaggacacaggcaggaaac accacgacggtgaacgtgatcaactgcaccgtcgactacctgctgcgccttcaggagtcc atcatggacttctactggcactactcgtcgaaggaaattattgaccctgccggcaaggcc aacttcttcaaggccattggtgttgctagccaggtgttcaacaccctgactgaggtgatc cagggcccgtgcgtgggcaaccagcagacgctcgctcactcccgtctgtgggacgccgtc ggcggctttctcttcctgttcgccaacatgcaggacaagctcagcaagcattcctcccag gtggatctgctgaaggatctgctcaacctccagaaggacatggtcatcatgatgctctct atgcttgagggtaacgtggtaaatggtaccattggtaagcagatggtggacaccttagtg gagagcgcttctaatgtcgagctgattctgaggtacttcgatatgttcctaaaactgagg gacctcacgagctcgaccaccttccaggaactagacaccaacaaggatggcactgtcacg cccatcgagttcaaggagaagatggaacagcagaagaactacaccaccgaggagatcaac ttcctcctcatgtgctgcgacacgaaccacgacggcaagatcgactacgtggagttcacc gagcgcttccacaaccccgctaaggaaatcggcttcaacttggccgtgctgctgactaac ctgtccgaacacatgcccaacgaacctcgacttgcgcgcttccttgagactgccggctct gtcctgaactacttcgagcctttcctgggccgaatcgagatcatgggcagctcgaagcgc atcgaacgcgtgtacttcgagatcaaggaggagaacatcgaccagtgggagaagcctcag atcaaggactcgaagcgcagtttcttctacgccatcgtcacagagggagacaaggagaag ctggaggccttcgtcaacttctgcgaggacgccatctttgagatgcagcacgccaccgcc ctgatggaagaggaagacgacgccatgtccaagaaatcgaacgcggacggcctcaagtac ctcagtgaagacgaagaagaaaagaccggcatggacctgatcaagtcgaagatcggaggc gtgaaggaccagatgctcgagggcctctcggtcttcgctccttccaacctcaagaagaag atcaaggaaatcaagcagatgtcctccaccgaactcgcagttggcttctgtcgcctcctg ttcctcatcatgtaccacagcgcgtttggagtggtctacgtgttgcgcaaagtgtggcag gctctcatgggtctcatgcaaggacctcccgcggaaaaggctgaagaaaaggaagagaaa gcagggccgttagtaccgttagcagtaccggcgttaccagaaataccggaaggagatgct gcgccgcccgctgaagaaggcaaaaaaccggaaggcgaacaattatccctggaggccgcg gatttgacgcaagaggagaaggtgaagcccatcttagacgccctggctgacctcaaggag gacatcactgccgaagaggcgatctcggctgccaaattggctgagaagaaggaagtggag accgcacaggccgccgccatggaggaggccgaggtggttgagagctccgccgcagcagaa cctccacccgtggctcaggtcgatctcagtggttacaacaagcgagctgtcagcttcctg gccaggaacttctacaatctgaagtacgctgctctggtgcttgccttctgcatcaacttc attcttctgttcttcaaggctaccgtagtcgaaatcgaggaggaggaaggcgaagacacg gacgtcaacaacccgttcgcgttcggatctggagacctactgggatccggcgacgaagcg gttctcggggacgacgcagcggatgaactcggctcgggcaacttcaccctcggagaagac gacgacgaagacgaggaagatgaagaggaagaggaatggatccacatggacgaccgctac ttctacctgtcccacatcttgaggttgttgaccaccactcactccattgtcgcgctctgc atgctgctcgcttactaccatctcaagatcccgctggtgatcttcaagcgcgagaaggac gtggcccgacgactggagttcgacggtatctacgtggccgaacagcccgaggacgacgac atcaaggcccactgggacaagctggtcatctcggcgaagagcttccccaacaactactgg gacaagtttgtgaagaagaaggtccgtgagaagtacagcgagacctacgacttcgacgcc atctcgaacctcttaggaatggagacgaccatgtcctttaagcaagaggaagtgccaacg ggcatcatcggatacctttcttcggtcgactggaagtaccagatctggaaggcaggcgtc accatcactgacaatcaattcttgtacaacctttggtacctgaccttctccttgctgggc aacatcaactacttcttcttcgctgctcacttgctcgatgtggctgtgtccatcccatca ctgaagacgatcttgcagtccgtcacccacaacggcaaacagctcatcctcacctgcatg ttgctgacgattatcgtgtactgctacactgtcatcgccttcaacttcttcaggaaattc tacgtgtcagaagaggatgatgttgtcgaccagaagtgccacgacatgttgacgtgcttc gtgttccacttgtacaagggcgtgcgcgctggtggtggtattggtgacgagatcgaggct cccgacggcgacgagtacgagttctaccgtatcgtcttcgacatcaccttcttcttcttc atcattgtcatcttgctggctatcattcagggtttgatcattgacgcctttggtgagctg agagaccagctggagtcggtgaaggagaacctggagagcaactgcttcatctgcggtata ggcaacgactacttcgacgcggtaccgcatggcttcgatatgcacacgcagaaggagcat aacttagctaattacatgttcttcttgatgcatttgatcaacaaagatgagacggagtac acgggtcaggagacgtacgtctggaacatgtaccaagaaaggtgctgggacttcttcccc gtcggcgactgcttcaggaagcagtacgaggaagagctctctggcggagcgtctgccagt tga

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