Pteropus vampyrus (large flying fox): 105288707 Help Entry 105288707         CDS       T07815                                  Symbol SPG11 Name (RefSeq) spatacsin isoform X4   KO K19026   spatacsin Organism pvp  Pteropus vampyrus (large flying fox) Pathway pvp04142   Lysosome pvp05014   Amyotrophic lateral sclerosis pvp05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:pvp00001]  09140 Cellular Processes   09141 Transport and catabolism    04142 Lysosome     105288707 (SPG11)  09160 Human Diseases   09164 Neurodegenerative disease    05014 Amyotrophic lateral sclerosis     105288707 (SPG11)    05022 Pathways of neurodegeneration - multiple diseases     105288707 (SPG11)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03400 DNA repair and recombination proteins [BR:pvp03400]     105288707 (SPG11) DNA repair and recombination proteins [BR:pvp03400]  Eukaryotic type   DSBR (double strand breaks repair)    HR (homologous recombination)     Other HR factors      105288707 (SPG11) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Spatacsin_C DUF6308 Rop Motif Other DBs NCBI-GeneID:  105288707 NCBI-ProteinID:  XP_011353340 UniProt:  A0A6P3Q5Q9 LinkDB All DBs Position Unknown AA seq 2464 aa AA seqDB search MAAEKWSGSAAASSSCNHKAMERVLPMLLVPVPAEATGRLGSRAQLHREQEVLGSLTAAG SLQVLSLAPGGRGGGGCCLDGPFRHFVWEDCHNSGTPTDKPRLLALSENYELLIYEFNLK DGRCDGTILYSYTEETLQKLIEDQNISISLLSLRILSFHNNTSLLFINKSIILRIIFPER DAEIRVLNCFTLPLPTQAVDRIIDTQLCRGILFVLSSLGWIYIFDMVDGTHVAHVDLTLH QEDMCNEQQQQPANISSFISLKVSQDLDVVVIVSSSNSAVALNLNLYFRQHPGHILRERT LQDFPIEGPKGIDEDDPVNSDYNMKLTKFSFQVDRSWKAQLSSLNKTIKSSKLEFSHCVP WFQDILHLEFPESLNHSMNAPSWPFIPQDIMHSQYNFPQKDHTKTSDPGRAWKMMHISEQ EEPIELRCVSVTRFTALFTWAVERMGCTIVLWDLETQGMQCFFLGQKCIPIDNSGDQQLC LVLTENGLSLILFGLSQEEFLNRLMIHGSASTVDSLCHLNGWGRCSIPIHALEAGIENRQ LDTVDFFLKSKENLLNPSSKSSVSDQFDHFPSHLYLRNVEELTPALDLLCSAIRESDSET QSKNFSEQLLNLTLSFLNKQIKEIFIHHEELDEHLKKGVNILTSYINELRTFMIKFPWKL TDAIDEYDVNENVPKVKESNIWEKFSIEDVIANAILNNKIPEAQTFFRINSHSAQRLEEL IRIGLDLVFDNLKKNNVKEASELLKNMGFDVKDQLLKICFYTTDKNIRDFLVEILKEKNY FSEKENGTIDFVHQVEKFYSEYLQENMQIQSFPRYWIKEQDFFKHKSVLDSFLKYDQKDK LNKQNHRIALNWAQWWNQLTQESILLPRINPEAYKSCSPEALWRYLTARHDWLSIISWIG EFQTHNSYASLQQNKWPPLTVDVIDQNTCCNDNMRNKILDDLARNGIFLTSELEDFELFL LRLNHIGGVMQDTLPVQNYRSKEGWDFHSRFILYCLEHNLQYLLYVYLDYYKLSPSNCPF LEKKELHEAHPWFEFLVQCRQVSSNLTDPKLIFQASLANAQILIPSNQASVSSMLLEGHT LLALATTMYAPGGVSQVVQNEENESCLKKVDPQLLKMALAPYPKLKTALFPQYTAPSVLP PDITLYHLIQSLSPFDPSRLFGWQSANTLAIGDAWSHLPHFSSPDLVNKYAIVERLNFAY YLHHGRPSFAFGTFLVQELTKSKTPKQLIQQVGNEAYVLGLSSFCIPSIGAACVCFLELL GLNSLKLRVDMKVANIILSYKCRNEDAQYSFIRESLAEKLSKLAADEKATIEELLILLEE GIWNSIQQQEIKRLSSESSSQWALVVQFCRLHNMKLSTSYLRECAKANDWLQFIIHSQIH NYHPEEVKSLLQYFSPVLQDHLRLAFENLSSVSNSRMDNDQVCIKPPKELQRSKEEMTDF FEILLQCSEEPHSWCWLLAEAVKQQAPVLSVLASCLQDASAIPCLCVWIITSVEDSVAAE AMGHIQGSVEGHTWDLEDLSVIWRTVLTRQKSKTLIRGFQLFFKDSPLLLMMEMYELCMF FKNYKEAEAKLLEFQKNLETLETAAASVHTVIPFPWLKEQVCFLLKLMLQQCRTQYELGK LLQLFVGIEHLFSHGPDVKKLYVLSQILKDTSIAINRVIITTYSLENFQHECRSVLEKLE TNGQFALARRVAELAELPVDNLVIEEVIQEMQTLKHIDQWSLKQARIDFWKKCHENFKKN SISSKAATSFFSAQALVACEYPTEEGPSSIEERHLLLTLAGHWLAQEDLVPVEKLEELEK QIWLCRITRHTLRGHQEEMEPRFSQQISISGELSFDSLASEFSFSKLAALNTSKYLELNG LPSKETCEDRLDWKEQKSLNFLIGRLLDDGCVHEASRVCRYFHFYNQDVALVLHCRALAS GEASVDDLHPEIHALLQSAELLEEEEEPHIPLRKVSSTSSLDSQSFVMLPHRDEVVTNLE TLTRKCLHGKNYCRQVLCLYELSKELGCSYTDVATRDGEATLRAILASQQPNRCKQAQAF ISTQGLEPDTVAELVAEEVTRELLSPSEGAGHKQMSTPAEESQTFLQLTTLCQDRTLVGM KLLDKISSVPHGELSCTTELLILAHHCFTLTCHMEGIIRVLKAARLLTDNHLAPNEEYGL VVRLLTGIGRYNEMTYIFDLLHKKHYFEVLMRKKLDPSGTLKTALLDYIKRCRPGDSEKH NMIALCFSMCREIGENHEAAACIQLKLIESQPWEDSLKDGHQLKQLLLKALTLMLDAAES YAKDSCVRQALHCHRLTKLLTLQIHFLNTGQNTMLINLGRHRLMDCIMALPRFYQASIVA EAYDFVPDWAEILYQQVILKGDFNYLEEFKQQKLLNSSIFEEISKKYKQHQPTDTVVKNL KKLLTYCEDVYLYYKLAYEHRFYDVVNVLLKDPQTGCCLKDMLAGVYLKKPKMHLNFNLK DDVQ NT seq 7395 nt NT seq  +upstreamnt  +downstreamnt atggctgcagagaagtggtccggaagtgctgccgcaagcagtagttgcaaccataaagcc atggagcgggttttacctatgttgttggtgccggtccccgccgaggcaacggggcggctg ggatcccgggcgcagttgcacagagagcaggaggttctggggagcctgacggctgcaggc agccttcaagtgctttccttggcgccaggcggccggggcgggggtggctgctgcctcgac ggcccctttcggcactttgtgtgggaggattgtcataacagcggtacaccaacagacaag cccagactgctcgctcttagtgaaaattacgaactgctcatctatgaatttaatttgaaa gatggacgatgtgatggaaccattttatatagctatactgaggagacattgcaaaagctc attgaagatcaaaatatcagtatttccttattatctttgagaattctgtcatttcacaat aacacatcattattgttcatcaataaaagtatcatcctacgcattatattccctgaaaga gatgctgagattagagtactcaactgtttcacattacccttgcctacacaggcagtggac agaattattgacacgcagctctgcagaggaattctttttgttttgagtagtttaggttgg atctacatatttgacatggtggatggtacacatgtagctcatgtggatttaacacttcac caagaagatatgtgtaatgagcagcaacagcagccagccaatatttcttcctttatttca ctgaaagtgtctcaagacctagatgttgtagtgattgtcagctcctccaactctgcagtt gctctcaacttaaatctatatttcaggcaacacccaggacacatactgcgtgaaagaact ctacaagactttcctatcgaaggccctaaggggatagatgaagatgatcctgttaattct gactacaacatgaaactgaccaagttttccttccaagtggataggtcttggaaagcccag ctatcatcattgaataagacaataaagagctccaaactggagttttcccattgcgttcca tggttccaggatattttgcatttggagtttcctgaatctcttaaccacagtatgaatgcg ccaagctggcctttcattccacaggacataatgcacagtcagtataattttccacagaaa gatcatactaagaccagtgatccaggaagagcatggaaaatgatgcacatcagtgaacaa gaggaacccatcgagcttagatgtgtgtctgtgacaagattcactgcactgtttacttgg gcagtggaaaggatgggctgcaccattgtcctttgggatttggaaacccagggcatgcag tgctttttccttggccagaaatgtattcctatagacaatagcggagaccagcaattgtgc cttgttttgacagaaaatggactgtctctgattttgtttggtttgtctcaagaagagttt ttaaatagactaatgatccatggaagtgccagcactgtggactctctttgccatctcaat ggttggggaaggtgctcaatccccatacatgccctagaggccggtatagaaaatcgtcag ctagacacagtagatttctttttgaagagcaaggaaaatcttttgaatccatcctcaaaa tcatctgtatctgatcagtttgatcactttccatcccatttatatttaagaaatgtggaa gagctgacaccagcattggatttactttgctcagcaattagagaaagtgattctgaaacc cagagcaaaaacttctcagaacaattgcttaatcttacactgtccttccttaacaaacaa ataaaggagatttttattcatcatgaagagctagatgaacatctaaagaaaggagtgaac attttgaccagctacattaatgaacttcgaactttcatgataaagtttccttggaagcta acagatgctatagatgaatatgatgtaaatgaaaatgtcccaaaagtaaaggagagcaat atctgggagaaattcagcattgaggacgttattgccaatgccattttaaacaacaaaata ccagaggcacagactttcttcaggattaatagtcattctgctcaaagactcgaggagctg attagaataggcttagatttggtctttgacaatttgaaaaagaacaatgtaaaggaagcc tctgaacttttaaagaatatgggctttgatgtaaaagaccagttgctcaagatatgcttc tatacaactgataaaaatatacgggattttttggttgaaattttaaaagaaaaaaattat ttttctgaaaaagagaatggaactatagacttcgtgcatcaagttgagaagttttattca gaatatttgcaagaaaatatgcagatccagtcatttcccaggtattggataaaggaacaa gattttttcaagcacaagtctgttttggactcattcctgaaatatgatcaaaaagataaa cttaacaagcagaaccatagaattgcgttaaattgggcccagtggtggaatcagctaaca caagaatccatccttctccccaggataaatccagaagcatacaaatcatgttctcctgaa gccctctggagataccttacagctcgccatgactggttaagcattatctcatggattgga gaatttcagacccataatagttatgcctcacttcagcaaaacaaatggccccctctgact gttgatgttattgatcagaacacttgctgcaacgataacatgaggaataaaattttagat gacctggccaggaatgggatttttcttacatctgaactagaagactttgaactcttcctc ctaagactgaaccatattgggggtgtgatgcaagacaccctccctgttcaaaactacagg tccaaagaaggttgggatttccattctcgcttcattctctattgtttggaacacaatctt cagtatcttctttacgtctatcttgactattacaaacttagcccttcaaattgccccttt ttggaaaaaaaagaattacatgaagctcacccttggtttgaatttttagtgcaatgtcga caggtttccagtaacttaacagatcctaaactcatcttccaggctagccttgcaaatgcg cagatactgattcccagtaaccaggccagtgtaagcagtatgctgttggagggacatacc ctcctcgccctcgctaccacaatgtatgctcctgggggtgtcagccaggttgttcagaat gaagaaaatgagagctgtttgaagaaagtagatccccagctactgaagatggcattagct ccttatcctaagctaaaaacggctctcttcccacagtatactgcccctagtgtcctgcca cctgatattacactctaccaccttattcagtcattatcgccctttgatcccagcagattg tttggctggcaatctgccaacacactagctataggagatgcatggagtcatctcccacat ttctctagccctgacctggttaataaatatgctatagtggaacgtctgaattttgcttat tatttacatcatggacggccatcatttgcatttggtacttttctggtccaggaattaact aagagcaagacacccaaacagctgatccagcaagtaggcaatgaagcttatgttttaggc ctctcctccttctgcataccttcaataggagctgcctgtgtttgtttcttagaattgctt ggcctcaacagcctcaagctcagagttgatatgaaagtggccaatataattctgagctac aaatgtagaaatgaagatgctcagtacagctttatcagagaatctctagctgaaaaacta tctaaactggctgcagatgaaaaggcaaccatagaagaattgctcattctcttagaagaa ggtatatggaacagcattcagcaacaggaaataaagaggttatccagtgaatctagcagc caatgggcattagtggtacagttctgcaggctccacaatatgaaactgagcacatcttac cttagagaatgtgccaaagcaaatgattggttacagttcattattcacagccagatccat aattaccatccagaggaggtgaaatcccttctccaatatttcagccctgtccttcaagac catttaaggctggcttttgagaacttgtcctcagtgtccaactccagaatggacaatgat caagtctgcatcaagccccccaaggaactccagagaagcaaagaagagatgactgatttt ttcgaaattctgcttcagtgctcagaggagccacactcctggtgctggctcctggctgaa gcagtgaaacaacaggcccctgttcttagtgttctggcctcatgtctccaggatgccagt gctattccctgtctctgtgtttggatcatcacttctgtggaggacagtgttgcagctgaa gcaatgggacacattcaaggctcagtggagggccacacttgggaccttgaggacctctca gtcatctggagaactgtattaacaaggcagaagagcaaaactctcatcagaggtttccaa cttttctttaaggattccccattactattgatgatggagatgtatgaactgtgtatgttc ttcaagaattataaggaagccgaagccaaattactggagttccagaagaacctcgaaact cttgaaacagcagccgcaagtgtccacactgtcatccctttcccatggctgaaggagcag gtgtgttttcttttgaagctaatgctacaacagtgtaggacccagtatgagctggggaag cttttacagctgtttgttggaatagagcatctcttctctcatggtccagatgtaaagaaa ctgtatgtccttagccagattttgaaggatacatccatagccattaatcgtgtaattata accacctatagccttgagaattttcagcacgaatgtagatctgttttggaaaaactggag acaaatggacaatttgctttagccaggagagtcgcagaattagctgagttacctgtggac aacttggttattgaagaggtaatacaggaaatgcagaccttaaagcacattgaccagtgg tccctgaaacaagcaagaattgacttctggaaaaaatgccatgagaattttaagaaaaat tccatttcaagcaaagcagctacttcctttttctcagcccaggcccttgtggcctgtgag tacccaactgaggagggaccgagcagcattgaggagcgccatctgctgctcaccctggca ggacactggcttgctcaggaggaccttgtacctgtggagaagttggaagagctggagaag cagatctggctctgccgtatcacccggcacaccctcagaggacaccaggaagaaatggag cccagattttctcaacagatctcaattagtggtgagctttcctttgatagcttagccagt gagttttcattctccaagttggctgctctgaacacatcaaaatatttagaacttaatggc cttccatccaaagagacttgtgaggacagactggattggaaggagcagaagtcactaaac tttttgattgggcgcctgttggatgatggctgtgtgcatgaagcaagtagagtatgccgg tattttcatttctataaccaagatgttgccttggtattgcactgcagagcactggcttca ggggaagctagtgtggatgacctgcatccagaaatccatgccctcctacagagtgctgag ctgctggaggaagaagaagaacctcacattcctctaaggaaagtctcaagcacttcaagt ttggatagtcagtcatttgtgatgctgccccacagagatgaagtggtgactaatctggaa actctgacaagaaaatgcctccatgggaagaactactgccggcaggtcctctgtctgtat gaactttccaaggagttgggctgttcctacacagacgttgccacccgggatggtgaggcc acgctccgagcaatcttggcctctcagcaacccaacagatgcaagcaagcccaagccttc atcagcacccaaggccttgagccagacacggtggctgaacttgtggccgaagaggtgacc cgggagctgctctccccatcagagggagcaggacataagcagatgtctactccagcagag gaaagccagacatttcttcagctgactactttgtgtcaagatcgcacgttggtaggcatg aagttgttggataagatttcctccgttccccatggggaattgtcttgcactacagagctg ctaatcctggcccatcactgcttcacactgacatgccacatggagggcatcatccgagtc ctgaaggctgcccggctgctcacagacaaccacttggcccccaacgaggagtatgggcta gtggtgcgtcttctcactggcattggaaggtacaacgagatgacatacatatttgatttg ctgcataaaaaacactactttgaagtgctgatgaggaagaagttggatccaagtggtacc ctgaagacggccctactcgactacatcaaacgttgccgccctggggacagtgagaagcac aacatgattgccctgtgcttcagcatgtgcagggagatcggggagaaccatgaggcagct gcttgcatccaactgaaactgattgagtctcagccttgggaggacagcctcaaggacggg caccaactgaagcagctgctgttaaaagccctcactctgatgctggatgcagcagaaagt tatgccaaggactcctgcgtgcgccaggccctgcactgtcaccggctcaccaagttgcta acactgcagattcactttctgaacactggccaaaacacaatgctcatcaacctgggccgc cacaggctgatggactgcatcatggccctacctcggttctaccaggcttctattgtagct gaggcctatgactttgttcctgattgggctgaaattctataccaacaagtgatacttaaa ggggactttaattacttggaagaatttaagcagcaaaagttattaaattccagtatattt gaagagatttcaaaaaaatataaacaacatcaacctactgacacagttgtgaaaaacctg aagaagttacttacatattgtgaagatgtctacttgtattacaagctggcatacgaacac agattttatgatgttgtaaatgtgcttctgaaggatccacagacaggttgctgtctaaag gacatgctagcaggtgtttatcttaagaaaccaaagatgcacttaaattttaacctcaag gatgatgtccaataa

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