Pteropus vampyrus (large flying fox): 105289813 Help Entry 105289813         CDS       T07815                                  Symbol ADCY3 Name (RefSeq) adenylate cyclase type 3   KO K08043   adenylate cyclase 3 [EC:4.6.1.1] Organism pvp  Pteropus vampyrus (large flying fox) Pathway pvp00230   Purine metabolism pvp01100   Metabolic pathways pvp01522   Endocrine resistance pvp04015   Rap1 signaling pathway pvp04020   Calcium signaling pathway pvp04022   cGMP-PKG signaling pathway pvp04024   cAMP signaling pathway pvp04062   Chemokine signaling pathway pvp04072   Phospholipase D signaling pathway pvp04081   Hormone signaling pvp04082   Neuroactive ligand signaling pvp04114   Oocyte meiosis pvp04211   Longevity regulating pathway pvp04213   Longevity regulating pathway - multiple species pvp04261   Adrenergic signaling in cardiomyocytes pvp04270   Vascular smooth muscle contraction pvp04371   Apelin signaling pathway pvp04540   Gap junction pvp04611   Platelet activation pvp04713   Circadian entrainment pvp04714   Thermogenesis pvp04723   Retrograde endocannabinoid signaling pvp04724   Glutamatergic synapse pvp04725   Cholinergic synapse pvp04727   GABAergic synapse pvp04740   Olfactory transduction pvp04750   Inflammatory mediator regulation of TRP channels pvp04911   Insulin secretion pvp04912   GnRH signaling pathway pvp04913   Ovarian steroidogenesis pvp04914   Progesterone-mediated oocyte maturation pvp04915   Estrogen signaling pathway pvp04916   Melanogenesis pvp04918   Thyroid hormone synthesis pvp04921   Oxytocin signaling pathway pvp04923   Regulation of lipolysis in adipocytes pvp04925   Aldosterone synthesis and secretion pvp04926   Relaxin signaling pathway pvp04927   Cortisol synthesis and secretion pvp04928   Parathyroid hormone synthesis, secretion and action pvp04934   Cushing syndrome pvp04935   Growth hormone synthesis, secretion and action pvp04962   Vasopressin-regulated water reabsorption pvp04970   Salivary secretion pvp04971   Gastric acid secretion pvp04972   Pancreatic secretion pvp04976   Bile secretion pvp05032   Morphine addiction pvp05163   Human cytomegalovirus infection pvp05166   Human T-cell leukemia virus 1 infection pvp05200   Pathways in cancer pvp05207   Chemical carcinogenesis - receptor activation pvp05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:pvp00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     105289813 (ADCY3)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     105289813 (ADCY3)    04371 Apelin signaling pathway     105289813 (ADCY3)    04020 Calcium signaling pathway     105289813 (ADCY3)    04072 Phospholipase D signaling pathway     105289813 (ADCY3)    04024 cAMP signaling pathway     105289813 (ADCY3)    04022 cGMP-PKG signaling pathway     105289813 (ADCY3)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     105289813 (ADCY3)    04081 Hormone signaling     105289813 (ADCY3)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     105289813 (ADCY3)   09144 Cellular community - eukaryotes    04540 Gap junction     105289813 (ADCY3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     105289813 (ADCY3)    04062 Chemokine signaling pathway     105289813 (ADCY3)   09152 Endocrine system    04911 Insulin secretion     105289813 (ADCY3)    04923 Regulation of lipolysis in adipocytes     105289813 (ADCY3)    04912 GnRH signaling pathway     105289813 (ADCY3)    04913 Ovarian steroidogenesis     105289813 (ADCY3)    04915 Estrogen signaling pathway     105289813 (ADCY3)    04914 Progesterone-mediated oocyte maturation     105289813 (ADCY3)    04921 Oxytocin signaling pathway     105289813 (ADCY3)    04926 Relaxin signaling pathway     105289813 (ADCY3)    04935 Growth hormone synthesis, secretion and action     105289813 (ADCY3)    04918 Thyroid hormone synthesis     105289813 (ADCY3)    04928 Parathyroid hormone synthesis, secretion and action     105289813 (ADCY3)    04916 Melanogenesis     105289813 (ADCY3)    04925 Aldosterone synthesis and secretion     105289813 (ADCY3)    04927 Cortisol synthesis and secretion     105289813 (ADCY3)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     105289813 (ADCY3)    04270 Vascular smooth muscle contraction     105289813 (ADCY3)   09154 Digestive system    04970 Salivary secretion     105289813 (ADCY3)    04971 Gastric acid secretion     105289813 (ADCY3)    04972 Pancreatic secretion     105289813 (ADCY3)    04976 Bile secretion     105289813 (ADCY3)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     105289813 (ADCY3)   09156 Nervous system    04724 Glutamatergic synapse     105289813 (ADCY3)    04727 GABAergic synapse     105289813 (ADCY3)    04725 Cholinergic synapse     105289813 (ADCY3)    04723 Retrograde endocannabinoid signaling     105289813 (ADCY3)   09157 Sensory system    04740 Olfactory transduction     105289813 (ADCY3)    04750 Inflammatory mediator regulation of TRP channels     105289813 (ADCY3)   09149 Aging    04211 Longevity regulating pathway     105289813 (ADCY3)    04213 Longevity regulating pathway - multiple species     105289813 (ADCY3)   09159 Environmental adaptation    04713 Circadian entrainment     105289813 (ADCY3)    04714 Thermogenesis     105289813 (ADCY3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105289813 (ADCY3)    05207 Chemical carcinogenesis - receptor activation     105289813 (ADCY3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     105289813 (ADCY3)    05163 Human cytomegalovirus infection     105289813 (ADCY3)   09165 Substance dependence    05032 Morphine addiction     105289813 (ADCY3)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     105289813 (ADCY3)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     105289813 (ADCY3)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     105289813 (ADCY3) Enzymes [BR:pvp01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      105289813 (ADCY3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N Motif Other DBs NCBI-GeneID:  105289813 NCBI-ProteinID:  XP_023384268 UniProt:  A0A6P6CAB0 LinkDB All DBs Position Unknown AA seq 1105 aa AA seqDB search MPRNQGFSDPEYSAEYSAEYSVSLPSDPERGVGRTHEISVRNSGSCLCLPRFMRLTFVPE SLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSRDQLAPLVVAGIWLLLDIV LFVLCKKGLLPDRVTRKVVPYLLWLLITAQIFSYLGLNFARAHAASDTVGWQAFFVFSFF ITLPLSLSPIVVISVVSCMVHTLVLGVTVAQQQQDGLKGMQLLREILASVSLYLCAVIVG ITSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQVRLFGVAQGSPGLELGFRSYGWGAG PVRRGLGTTAPARPFQKYHQLRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISY VREKTKTGVDMRVGVHTGTVLGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQST LDCLKGEFDVEPGDGGSRCDYLDEKGIETYLIIASKPEVKKTAVQNGLNGSALPNGAPPS SQPSSPALIETKEPNGSVHASGSTSEEPEEQGAQADNPSFPNPRRRLRLQDLADRVVDAS EDEHELNQLLNEALLERESAQVVKKRNTFLLSMRFMEPEMETRYSVEKEKQSGAAFSCSC VVLLCAALGEMLVDPWLMTNYVTFVVGEVLLLILTICSLAAIFPQAFPKKLVAFSTWIDR TRWARNTWAMLAIFILVMANVVDMLSCLQYYTGPSNGTAGMEMEDGCTENPKYYNYVAVL SLIATIMLVQVSHMVKLTLMLLITGAVAVVNIYAWCPIFDEYDRRRFQEHDFPVVALEKM QILSTAGLNGTDRLPLLPSKYSMTAMIFVMMLSFYYFSRHVEKLARTLFLWKIEVHDQKE RVYEMRRWNEALVTNMLPEHVARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEE SINNGGIECLRFLNEIISDFDSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFTSS NKEEKSDKERWQHLADLADFALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKP HYDIWGNTVNVASRMESTGVMGNIQVVEDTQAILREYGFRFVRRGPIFVKGKGELLTFFL KGRDKPATFPNGSSVTLPHQVVDNS NT seq 3318 nt NT seq  +upstreamnt  +downstreamnt atgccgaggaaccagggcttctccgaccccgagtactcggcggagtactcggcggagtac tccgtcagcctgccctctgaccctgagcgcggggtgggccggacccatgaaatctctgtg cggaactcggggtcctgcctctgcctgcctcgctttatgcggctgaccttcgtgcccgag tccttggagaacctgtaccagacctatttcaaaaggcagcgccatgagaccctgctggtg ctggtggtcttcgcagccctcttcgactgctacgtggtggtcatgtgcgctgtggtcttc tcccgcgaccagctggctcccctcgtggtggctgggatctggctgctgttggatatcgtc ctcttcgtgctctgcaaaaagggactgctcccggaccgggtcacccggaaagtggtgccc tatctactgtggctgctgataacagcccagatcttctcctacttgggcctgaactttgcc cgcgcccatgcggccagcgacacagtgggctggcaggccttctttgtcttctccttcttc atcacgctgcccctcagcctcagccccatcgtcgtcatctctgtggtctcctgtatggtg cacaccctcgtcttgggggtcaccgtggcccagcagcagcaggatgggctgaaggggatg cagttgctgagagagatcctggccagtgtctccctgtacctttgcgccgtcatcgtgggc atcacgtcctactacatggcagaccgcaagcaccgcaaggccttcctggaggcccgccag tcgctggaggtgaagatgaacctggaggagcagagccagcagcaggtgaggctcttcggg gtggcccagggcagtccgggcttggagcttgggttcaggagctatggctggggcgcgggg cctgtcaggaggggactcgggaccacagcccctgcccggccctttcagaaataccaccag ctgcgcattaagatcctgggcgactgttactattgcatctgtggcctgcctgactaccga gaggaccacgccgtctgctccatcctcatggggctcgccatggtggaggccatctcgtat gtgcgagagaagacgaagaccggggtggacatgcgtgtgggggtgcacacaggcaccgtg ctggggggcgtcctgggccagaagcgctggcagtacgatgtttggtccactgatgtgact gtggccaacaagatggaggccggcggcatccccgggcgtgtgcacatctcacagagcacc ttggactgcctgaagggggagttcgacgtggagccgggcgacgggggcagccgctgcgac tacctggatgagaagggcatcgaaacctacctcatcatcgcatccaagccagaggtgaag aagacggccgtccaaaatggcctcaatggctcggccctgcccaatggagccccgccttcc tcgcagcccagctcccccgccctcatcgagaccaaggagcccaacgggagtgtccacgcc agcgggtccacgtcggaggagcccgaggagcaaggggcccaggctgacaacccctccttc cccaaccctcgccggaggctgcgcctccaggacctggccgacagagtggtagacgcctcc gaggacgagcatgagctcaaccagctgctcaacgaggccctgctcgagcgggagtccgcc caggtagtgaagaagagaaacaccttcctcctgtccatgcggttcatggagcccgagatg gagacgcgctactcagtggagaaggagaagcagagcggagctgccttcagctgctcctgc gtcgtcctgctctgtgcggccctgggcgagatgctcgtcgacccctggctaatgacaaac tatgtgacctttgtggttggggaggttctgcttctgatcctgacgatctgctcgctggct gccatctttccccaggcctttcctaagaagctcgtggccttctcaacctggatcgaccgg acccgctgggccaggaacacctgggccatgttagccatcttcattctggttatggcaaat gtcgtggacatgcttagctgcctccagtactacacgggacccagcaacggcaccgcaggg atggagatggaggatggctgcacggagaaccccaagtattacaactatgtcgccgtgctg tcactcatcgccaccatcatgctggtgcaggtcagccacatggtgaagctcacgctcatg ctgctcatcactggcgctgtagccgtcgtcaacatctatgcctggtgccccatcttcgat gaatatgaccgcagacgtttccaggaacacgactttcctgtggttgccttggagaagatg cagatactctccaccgctgggctcaatggcactgacaggctgcccctgctgccctccaag tactcgatgacagcgatgatcttcgtcatgatgctgagcttttactacttctcccgccac gtggaaaaactggctcggacactgttcttatggaagattgaggtccatgaccagaaggaa cgtgtctatgagatgcgacgctggaatgaggccttggtcaccaacatgttgcctgagcac gtggcacgccatttcctggggtccaagaagagagatgaggaactgtacagccagtcttat gatgagattggagtcatgtttgcctccctgcccaacttcgctgacttctacacagaggag agcatcaataatggtggcattgagtgtctgcgctttctcaacgagatcatctcagatttt gactctctcctggacaatcccaaattccgggtcatcaccaagatcaaaaccattggcagt acctatatggcagcttcaggagtcaccccagatgtcaacaccaatggctttaccagctcc aacaaggaggagaagtcagacaaggagcgctggcagcacctggctgatctggctgacttc gcactagccatgaaggatacgcttaccaacatcaacaaccagtccttcaacaacttcatg ctgcgcataggcatgaacaaaggaggggtactggctggggtcattggagcccggaaacca cactatgacatctggggcaacacagtcaacgtagccagcaggatggagtccacgggggtc atgggcaacattcaggtggtagaagacacacaggccatcctccgagagtacggcttccgc ttcgtgaggcgagggcccatctttgtgaaagggaaaggggagctgctaacctttttcttg aaaggccgtgacaagccagccaccttccctaacggctcctctgtcacactgccccaccag gtggtagacaactcctga

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