KEGG   Pteropus vampyrus (large flying fox): 105289998
Entry
105289998         CDS       T07815                                 
Symbol
PDE11A
Name
(RefSeq) dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
  KO
K13298  dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 [EC:3.1.4.17 3.1.4.35]
Organism
pvp  Pteropus vampyrus (large flying fox)
Pathway
pvp00230  Purine metabolism
pvp01100  Metabolic pathways
pvp04934  Cushing syndrome
pvp05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:pvp00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    105289998 (PDE11A)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    105289998 (PDE11A)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    105289998 (PDE11A)
Enzymes [BR:pvp01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.17  3',5'-cyclic-nucleotide phosphodiesterase
     105289998 (PDE11A)
    3.1.4.35  3',5'-cyclic-GMP phosphodiesterase
     105289998 (PDE11A)
SSDB
Motif
Pfam: PDEase_I GAF GAF_2 GAF_3 HD-CE HD
Other DBs
NCBI-GeneID: 105289998
NCBI-ProteinID: XP_011355163
UniProt: A0A6P3PZA3
LinkDB
Position
Unknown
AA seq 933 aa
MTASHLDFGEVETFLDRHPELFEDYLMRKGKQDMVEKWLQRHSQRQGALGPRLALPGTSS
LAQVSGRGSSSIGGGTGSNGSANSQPTPGGGDCGGVPLSPSWASGSRGDGNLQRRASQKE
LRKSFARSKAIHVNRTYDEQVTSRAQEPLSSVRRRALLRKASSLPPTTAHILSALLESRV
NLPQYPPTAMDYKCHLKKHNERQFFLELVKDISNDLDLTSLSYKILIFVCLMVDADRCSL
FLVEGAAAGKKSLVSKFFDVHAGTPLLPCSSTENSNEVQVPWGKGIIGYVGEHGETVNIP
DAYQDRRFNDEIDKLTGYKTKSLLCMPIRSSDGEIIGVAQAINKIPEGAPFTEDDEKVMQ
MYLPFCGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKC
ERCSVLLLEDIESPVVKFTKSFELLSPKCSADAENSFKESMEKSSYSDWLINNSIAELVA
STGLPVNISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFD
DADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANI
PLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRM
VLYHNWRHAFNVCQLMFAMLTTAGFQEILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSG
SALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLY
FERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFE
QGDRERAELKLIPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMVDSVAA
NRSKWEELHQKRLLVSAASPSSASFMVAGADSN
NT seq 2802 nt   +upstreamnt  +downstreamnt
atgacagcttcccacctggactttggggaggtggaaactttcctggacaggcacccagag
ttgtttgaagattatttgatgcgtaaggggaagcaggatatggtggagaagtggctgcag
aggcacagtcagaggcagggggctttaggcccaaggctggcactgcctggcaccagcagc
ttggctcaagtcagtggcagaggcagcagcagcattggtggtggcactggatcaaatggc
tctgccaacagccagcccactccaggtggtggggactgtggcggagtacccttgagtccc
agctgggccagtggcagccggggtgatgggaacctgcagcgaagagcttctcagaaagag
ctaaggaagagttttgcccgctccaaagccatccacgtgaacaggacctatgatgaacaa
gtgacctcccgggcccaggagcccctgagcagtgtgcggcggagggcacttctccggaag
gccagctccctgccccccaccacagcccatattctcagtgccctgctggaatcgagggtg
aatctgcctcagtatccccctacagctatggactacaagtgccatctcaaaaagcataat
gagcgtcaattctttttggaactggtcaaagatatctccaatgaccttgaccttaccagc
ctgagctacaagatcctcatctttgtctgcctcatggtggatgctgaccgctgctctctc
ttcctggtggaaggggcggctgctggcaagaagagtttggtctccaaattcttcgatgtg
catgcgggaactccactgctgccctgcagcagcacagagaactcaaacgaggtacaggtc
ccttggggcaaaggcatcattggctatgtcggggaacatggagaaacagtcaacattcct
gatgcctaccaggatcgaagattcaatgatgaaattgacaagctaactggttacaagaca
aaatcgctgttgtgcatgcctatccgaagcagtgatggtgagattatcggtgtggcacaa
gcgataaataagattcctgagggtgctccatttactgaagatgacgaaaaagttatgcag
atgtatcttccgttttgtggaatcgccatatctaatgctcagctatttgccgcctcaagg
aaagaatatgaaagaagcagggcattgttagaggtggttaatgatctctttgaagaacag
actgacctggagaaaattgtcaagaaaataatgcatcgggcccaaactctgctgaaatgt
gagcgctgttctgttttactcctagaagacattgaatcgccagtggtgaagtttaccaaa
tcctttgaattgctgtccccaaagtgcagtgccgacgctgagaacagtttcaaagagagc
atggagaaatcatcgtactctgactggctgataaataacagcattgccgagctcgtggct
tctacaggtcttccagtgaacatcagtgatgcctaccaggaccctcgctttgatgctgag
gctgaccagatatctggttttcacataagatcggttctctgcgtacctatttggaatagc
aaccaccaaataattggagtggctcaagtgttaaacagacttgacggaaaaccttttgat
gatgcggaccaacgactttttgaggcttttgttatcttttgtggccttggcatcaacaac
acaattatgtacgatcaagtgaagaagtcttgggccaagcagtctgtggctcttgatgtg
ctatcataccatgcgacatgttcaaaagctgaagttgacaagtttaaggcagccaacatc
cctttggtgtcagaacttgccatcgatgacatacattttgacgacttttctcttgacgtt
gatgccatgatcacagctgctcttcggatgttcatggagctggggatggtacagaaattt
aaaattgactatgagacactgtgtaggtggcttttaactgtgaggaaaaattatcgaatg
gttctgtaccacaactggagacacgccttcaacgtgtgccaactgatgtttgcgatgtta
actactgctgggtttcaagagattctgactgaggtggaaattttagcggtgattgtggga
tgcttgtgtcatgaccttgaccacaggggaaccaacaatgccttccaagctaagagtggc
tctgccctggcccaactctatgggacctctgctaccttagagcaccaccactttaaccac
gccgtgatgatccttcaaagtgagggtcacaacatctttgctaatttgtcctccaaggaa
tacagtgacctcatgcaacttttgaagcagtcaatattggcaacagatctcactctgtac
tttgagaggagaactgaattctttgaacttgtcagtaaaggagaatatgattggaacatc
aaaaaccatcgtgatatatttcgatcaatgttaatgacagcctgtgaccttggagccgtg
accaaaccgtgggagatctcgagacaggtggctgaacttgtaaccagtgagttcttcgaa
caaggagatcgggagagagcagaactcaaactcattccttcagctatttttgatcggaac
cggaaagatgaactgcctcggttgcagctggagtggatcgatagcatctgtatgcctttg
tatcaggcactggtgaaggtcaatgtgaaactgaagccaatggtggattcggtggctgca
aacagaagtaaatgggaagagctgcaccagaaaaggctgctagtctcagctgcctcaccc
tcctctgccagcttcatggtggccggagcagatagtaactaa

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