KEGG   Pteropus vampyrus (large flying fox): 105290030
Entry
105290030         CDS       T07815                                 
Symbol
DDB2
Name
(RefSeq) DNA damage-binding protein 2 isoform X1
  KO
K10140  DNA damage-binding protein 2
Organism
pvp  Pteropus vampyrus (large flying fox)
Pathway
pvp03420  Nucleotide excision repair
pvp04115  p53 signaling pathway
pvp04120  Ubiquitin mediated proteolysis
pvp05161  Hepatitis B
pvp05169  Epstein-Barr virus infection
pvp05200  Pathways in cancer
pvp05202  Transcriptional misregulation in cancer
pvp05210  Colorectal cancer
pvp05212  Pancreatic cancer
pvp05213  Endometrial cancer
pvp05214  Glioma
pvp05216  Thyroid cancer
pvp05217  Basal cell carcinoma
pvp05218  Melanoma
pvp05220  Chronic myeloid leukemia
pvp05222  Small cell lung cancer
pvp05223  Non-small cell lung cancer
pvp05224  Breast cancer
pvp05225  Hepatocellular carcinoma
pvp05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:pvp00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    105290030 (DDB2)
  09124 Replication and repair
   03420 Nucleotide excision repair
    105290030 (DDB2)
 09140 Cellular Processes
  09143 Cell growth and death
   04115 p53 signaling pathway
    105290030 (DDB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105290030 (DDB2)
   05202 Transcriptional misregulation in cancer
    105290030 (DDB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    105290030 (DDB2)
   05212 Pancreatic cancer
    105290030 (DDB2)
   05225 Hepatocellular carcinoma
    105290030 (DDB2)
   05226 Gastric cancer
    105290030 (DDB2)
   05214 Glioma
    105290030 (DDB2)
   05216 Thyroid cancer
    105290030 (DDB2)
   05220 Chronic myeloid leukemia
    105290030 (DDB2)
   05217 Basal cell carcinoma
    105290030 (DDB2)
   05218 Melanoma
    105290030 (DDB2)
   05213 Endometrial cancer
    105290030 (DDB2)
   05224 Breast cancer
    105290030 (DDB2)
   05222 Small cell lung cancer
    105290030 (DDB2)
   05223 Non-small cell lung cancer
    105290030 (DDB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    105290030 (DDB2)
   05169 Epstein-Barr virus infection
    105290030 (DDB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:pvp04121]
    105290030 (DDB2)
   03400 DNA repair and recombination proteins [BR:pvp03400]
    105290030 (DDB2)
Ubiquitin system [BR:pvp04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul4 complex
    Target recognizing subunit (DCAF)
     105290030 (DDB2)
DNA repair and recombination proteins [BR:pvp03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     Cul4-DDB2 complex
      105290030 (DDB2)
SSDB
Motif
Pfam: WD40_CDC20-Fz WD40 WD40_Prp19 WD40_WDHD1_1st Beta-prop_EML_2 Beta-prop_WDR75_1st Beta-prop_RIG_2nd Beta-prop_WDR90_POC16_2nd WDR55 Beta-prop_EIPR1 Beta-prop_IFT140_1st Beta-prop_WDR19_1st Beta-prop_TEP1_2nd ANAPC4_WD40 EIF3I Beta-prop_TEP1_C Beta-prop_CAF1B_HIR1 Beta-prop_EML WD40_RFWD3 WD40_MABP1-WDR62_2nd Beta-prop_Vps41 NBCH_WD40 WD_LRWD1 Beta-prop_NWD2_C Beta-prop_SPT8
Other DBs
NCBI-GeneID: 105290030
NCBI-ProteinID: XP_011355247
UniProt: A0A6P3Q158
LinkDB
Position
Unknown
AA seq 427 aa
MASRKRPETRKTPEVVVRRKSKRNRSPRELEPEAKKLCVKGPGSSRRFDSGCLWAGLASL
QVSPPCRNIVRALYHHKVGKAAWPSLQQSLQHSFLQSLASYRIFQKAAPFDRRATSLAWH
PTHPSTLAVGSKGGDIMLWNFGIKDKPTFIKGIGAGGSITGLKFNPLNTNQFFTSSMEGM
TRLQDFKGNTLQVFASYSICNFWFCSLDVSAKSRVVVTGDNVGNVILLNMDGKELWNLRM
HKKKVTHLALNPCCDWFLATASVDQTVKIWDLRQVKGKSSFLYSLPHRHPVNAAHFSPDG
AQLLTTDQNSEIRVYSASQWDCPPSLIPHPHRHFQHLTPIKAAWHPRYNFIVVGRYPDPN
FKSCTPYELRTIDVFDGSSGKLMHQLYDPESSGIISLNEFNPMGDTLASLMGYHILIWSQ
EEAGMQK
NT seq 1284 nt   +upstreamnt  +downstreamnt
atggcttccaggaaacgcccagaaacccggaagacccctgaggtggtcgtgcgccgcaag
agcaagaggaacagaagcccccgagagttggagcccgaggccaagaagctctgtgtgaag
ggccccggttctagcagaagatttgactcgggctgcctttgggcggggttggctagcctg
caggtctcaccaccatgcaggaatatcgtcagggccctctatcaccataaagtgggcaaa
gctgcttggccatcactacagcagagtctccagcattcctttttgcagtctctggcttct
taccggatattccaaaaggctgccccctttgacaggagggccacatccttggcatggcac
ccaactcaccccagcaccctggctgtaggttccaaagggggagatatcatgctctggaac
tttggcataaaggacaaacctaccttcattaaagggattggagctggagggagcatcact
gggctgaagtttaaccctctcaataccaaccagtttttcacctcctcaatggagggaatg
actaggctacaagactttaaaggcaacactctccaagtttttgccagctacagcatctgc
aacttctggttttgcagcctggatgtgtctgccaaaagccgagtggtggtcacaggagac
aatgtagggaacgtgatcctgctgaacatggacggcaaggagctttggaatctgagaatg
cacaaaaagaaagtgacccatttggccctgaacccatgctgtgattggttcctggccaca
gcctctgtagatcaaacagtgaaaatctgggacctgcgccaggttaaagggaaatccagc
ttcctctactcactgccacacaggcatcctgtcaacgcagctcatttcagtcctgatgga
gcccagctgctgaccactgaccagaacagtgagatccgggtttactctgcctcccagtgg
gactgccccccgagcctgatcccgcaccctcaccgccacttccagcacctgacgcccatc
aaggcagcctggcatcctcggtacaacttcattgttgtgggccgatacccagatcctaat
ttcaaaagttgtaccccctatgaattaaggacaatcgatgtatttgatggaagctcaggg
aagttgatgcatcagctctatgacccagaatcttctggaatcatttcgctcaatgagttc
aatcctatgggagacacgctggcttctttgatgggttatcacattctcatttggagccaa
gaggaagctgggatgcagaaatga

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