Pteropus vampyrus (large flying fox): 105290270
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Entry
105290270 CDS
T07815
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
pvp
Pteropus vampyrus (large flying fox)
Pathway
pvp01521
EGFR tyrosine kinase inhibitor resistance
pvp01522
Endocrine resistance
pvp04010
MAPK signaling pathway
pvp04014
Ras signaling pathway
pvp04015
Rap1 signaling pathway
pvp04066
HIF-1 signaling pathway
pvp04068
FoxO signaling pathway
pvp04114
Oocyte meiosis
pvp04140
Autophagy - animal
pvp04144
Endocytosis
pvp04150
mTOR signaling pathway
pvp04151
PI3K-Akt signaling pathway
pvp04152
AMPK signaling pathway
pvp04211
Longevity regulating pathway
pvp04213
Longevity regulating pathway - multiple species
pvp04510
Focal adhesion
pvp04520
Adherens junction
pvp04550
Signaling pathways regulating pluripotency of stem cells
pvp04730
Long-term depression
pvp04913
Ovarian steroidogenesis
pvp04914
Progesterone-mediated oocyte maturation
pvp05200
Pathways in cancer
pvp05202
Transcriptional misregulation in cancer
pvp05205
Proteoglycans in cancer
pvp05214
Glioma
pvp05215
Prostate cancer
pvp05218
Melanoma
pvp05224
Breast cancer
pvp05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
pvp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
105290270 (IGF1R)
04014 Ras signaling pathway
105290270 (IGF1R)
04015 Rap1 signaling pathway
105290270 (IGF1R)
04066 HIF-1 signaling pathway
105290270 (IGF1R)
04068 FoxO signaling pathway
105290270 (IGF1R)
04151 PI3K-Akt signaling pathway
105290270 (IGF1R)
04152 AMPK signaling pathway
105290270 (IGF1R)
04150 mTOR signaling pathway
105290270 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
105290270 (IGF1R)
04140 Autophagy - animal
105290270 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
105290270 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
105290270 (IGF1R)
04520 Adherens junction
105290270 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
105290270 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
105290270 (IGF1R)
04914 Progesterone-mediated oocyte maturation
105290270 (IGF1R)
09156 Nervous system
04730 Long-term depression
105290270 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
105290270 (IGF1R)
04213 Longevity regulating pathway - multiple species
105290270 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
105290270 (IGF1R)
05202 Transcriptional misregulation in cancer
105290270 (IGF1R)
05205 Proteoglycans in cancer
105290270 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
105290270 (IGF1R)
05214 Glioma
105290270 (IGF1R)
05218 Melanoma
105290270 (IGF1R)
05215 Prostate cancer
105290270 (IGF1R)
05224 Breast cancer
105290270 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
105290270 (IGF1R)
01522 Endocrine resistance
105290270 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pvp01001
]
105290270 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
pvp04090
]
105290270 (IGF1R)
Enzymes [BR:
pvp01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
105290270 (IGF1R)
Protein kinases [BR:
pvp01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
105290270 (IGF1R)
CD molecules [BR:
pvp04090
]
Proteins
105290270 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Kinase-like
Insulin_TMD
Motif
Other DBs
NCBI-GeneID:
105290270
NCBI-ProteinID:
XP_023384752
UniProt:
A0A6P6CBH0
LinkDB
All DBs
Position
Unknown
AA seq
1369 aa
AA seq
DB search
MKSGSGGGSPTSLWGLLFFCVALSLWPATGEICGPGIDIRNDYQQLRRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGAMEGKPLCEKTSINNEYNYRCWTTNQCQKTCPSACGKRACTEDHECCHPECLGGCS
APDDDAACVACRHYYFAGVCVPSCPPSTYRFEGWRCVDRDFCANIPNAESSDTEGFVIHD
GECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDALHFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPSNKDIEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRH
NYCSKDKIPIRKYADGTFDIEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNSIFVPRPERKRRDVAQVANTTMSSRSRNSTADAYNVTDLEELETEYPFYESR
VDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAVSAVEDSVGFFPV
FYKSGSLSGGRRQTGPPVTRFSCVCGEVTRLFPSPQDQRECVSRQEYRKYGGAKLNRLNP
GNYTARIQATSLSGNGSWTDPVFFYVQAKTTYENFMHLIIALPIAILLIVGGLVIMLYVF
HRKRNSNRLGNGVLYASVNPEYFSAADVYVPDEWEVARDKITMSRELGQGSFGMVYEGVA
KGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVI
MELMTRGDLKSYLRSMRPEIENNLVLVPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAA
RNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSF
GVVLWEIATLAEQPYQGFSNEQVLRFVMEGGLLDKPDNCPDIMFELMRMCWQYNPKMRPS
FLEIIGSIKDEMEPGFQEVSFYYSDENKPPDMEELDLEPENMESIPLDPSASSLSLPLPD
RHSGHRAENGPGPGMLVLRASFDDRQPYAHMNGGRKNERPLPLPQSSTC
NT seq
4110 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcctgtttttctgc
gtcgcgctctcgctgtggccggcgaccggagaaatctgcgggcccggcatcgacatccgc
aacgactaccagcagctgaggcgcctggagaactgcacggtgatcgagggttacctgcac
atcctgctcatctccaaggccgaggactaccggagctaccgcttccccaagctcacggtc
atcaccgagtacctgctgctgttccgcgtggccggcctcgagagcctcggcgacctcttc
ccgaacctcacggtcatccgcggctggaagctcttctacaactacgccctggtcatcttc
gagatgaccaacctcaaggacatcgggctttacaacctgcggaacattacccggggggcc
atcaggatcgagaaaaacgccgacctctgctacctgtccacggtggactggtccctgatc
ctggacgccgtctccaacaactacatcgtggggaacaagcccccaaaggagtgtggggac
ctgtgtccaggggcaatggaggggaagccgctgtgcgagaagaccagcatcaacaatgag
tacaactaccgctgttggaccacaaaccagtgccagaaaacgtgcccgagcgcgtgcggg
aagcgggcctgcacggaggaccacgagtgctgccaccccgagtgcctgggcggctgcagc
gcgcccgacgacgacgcggcctgcgtggcctgtcgccactactacttcgccggcgtgtgc
gtgcccagctgcccgcccagcacctaccgcttcgagggctggcgctgcgtggaccgcgac
ttctgcgccaacatccccaacgcggagagcagcgacaccgagggcttcgtcatccacgac
ggcgagtgcatgcaggagtgcccctcgggcttcatccgcaacggcagccagagcatgtac
tgcatcccttgcgaaggaccttgccccaaagtctgcgaggaagaaaagaaaacgaagacc
attgattcggttacttctgctcagatgctccaaggatgcaccatattcaagggcaatttg
ctcattaatattcgacgaggcaataacattgcctcggagctggagaacttcatggggctt
attgaggtggtgacgggctacgtgaagatccgtcattcccacgccttggtgtccttgtcc
ttcctgaaaaaccttcgccagatcttaggagaggagcagctggaggggaattactccttc
tacgtcctcgacaaccagaacctgcagcagctgtgggactgggaccaccggaacctcacc
atcaaagccgggaaaatgtacttcgccttcaaccccaaactctgtgtctccgaaatttac
cgcatggaggaggtgacggggaccaaagggcgccagagcaaaggggacataaacaccagg
aacaacggagagagagcctcctgtgagagcgacgccctgcacttcacctcgaccacgacg
tggaagaaccgcatcatcatcacgtggcaccggtaccggccgccagactacagggacctc
atcagcttcactgtctactacaaggaagcaccctttaaaaacgtaacggaatatgatggg
caggacgcctgcggctccaacagctggaacatggtggacgtggacctcccttccaacaag
gacatcgagcccggcatcctactgcacgggctgaagccctggacgcagtacgccgtgtac
gtcaaggccgtgaccctgaccatggtggagaatgaccacatccgcggggccaagagcgaa
atcttgtacatccgcaccaacgcctcagttccttccatccccctggacgtcctgtccgcg
tccaattcctcttcccagctgatcgtgaagtggaacccgccctctctgcccaacggcaac
ctgagctactacatcgtgaggtggcagcgccagcctcaggacagctacctgtaccggcac
aattactgctccaaagacaaaatccccatcaggaagtatgccgatggcaccttcgacatc
gaggaggtgacggagaaccccaagacggaggtgtgcggtggggagaaggggccttgctgc
gcgtgccccaaaaccgaagccgagaagcaggcggagaaggaggaggccgagtaccgcaaa
gtcttcgagaacttcctgcacaattccatcttcgtgcccagacccgagcggaagcggaga
gatgtcgcgcaggtggccaacaccaccatgtccagccgaagcaggaacagcacggcggac
gcctacaacgtcacagacctggaagagctggagacggaatatcctttctacgagagcaga
gtggacaacaaggagagaaccgtcatctccaacctgcggcccttcactctgtaccgcatc
gacatccacagctgcaaccacgaggcggagaagctgggctgcagcgcctccaacttcgtt
tttgcaagaaccatgcctgcagtttctgctgtggaagactcggttggtttcttccccgtg
ttttacaaatcgggatcgctgtcaggcgggaggcgacagactgggccgccggtcacccgc
ttctcgtgcgtttgtggggaagtgacccgtctgtttccctcgccccaggaccagcgggag
tgcgtgtccaggcaggagtaccgaaagtacggaggggccaagctgaaccggctcaacccg
ggcaactacacggcccgcatccaggccacctctctgtccggaaatgggtcgtggacggac
cctgtgttcttctacgtccaggccaaaacgacctatgaaaatttcatgcacctgatcatc
gccctgcccatcgccatcctgctcatagtgggggggctggtgataatgctgtatgtcttc
caccggaaaagaaacagcaacaggctggggaatggagtgctgtacgcgtccgtgaacccc
gaatacttcagcgcggctgacgtgtacgtgcctgacgagtgggaggtggcccgcgacaag
atcaccatgagccgggagctgggccagggctccttcgggatggtgtatgagggcgtggcc
aagggcgtggtcaaggacgagcccgaaaccagggtggccattaaaaccgtgaacgaggcc
gcgagcatgcgcgagaggattgaatttctcaacgaggcttcggtgatgaaggagttcaac
tgtcaccacgtggtgcggctgctgggcgtggtgtcccagggccagccaacgctggtcatc
atggaactgatgacacgaggcgatctcaagagttacctcaggtccatgaggccggagatc
gagaataatctggtcctcgtgcctccaagcctgagcaagatgatccagatggcgggagag
atcgcggacggcatggcgtacctgaacgccaacaagttcgtgcacagagatctggccgcc
cgcaactgcatggtggccgaggatttcaccgtcaaaatcggagatttcggtatgaccaga
gacatctacgagacagactattaccggaagggagggaaaggcctgctgcccgtgcgctgg
atgtcccccgagtccctgaaggacggcgtcttcaccactcattctgacgtctggtccttc
ggcgtcgtcctctgggagatcgccacgctggccgagcagccgtaccagggcttctccaac
gagcaggtgctgcgcttcgtcatggagggcggcctgctggacaagccggacaactgcccc
gacataatgttcgagctgatgcgcatgtgctggcagtacaaccccaagatgcggccgtcc
ttcctggagatcatcggcagcatcaaggacgagatggagcccggcttccaggaggtgtcc
ttctactacagcgacgagaacaagccgcccgacatggaggagctggacctggagccggag
aacatggagagcatcccgctggacccgtcggcctcgtcgctgtccctgccgctgcccgac
agacactcaggacacagggccgagaacggcccgggcccgggcatgctggtcctccgggcc
agcttcgacgacaggcagccctacgcgcacatgaacgggggacgcaagaacgagaggccg
ctgcctctgccccagtcgtccacctgctga
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integrated database retrieval system
