Pteropus vampyrus (large flying fox): 105290755 Help Entry 105290755         CDS       T07815                                  Symbol TOP2B Name (RefSeq) DNA topoisomerase 2-beta   KO K03164   DNA topoisomerase II [EC:5.6.2.2] Organism pvp  Pteropus vampyrus (large flying fox) Pathway pvp01524   Platinum drug resistance Brite KEGG Orthology (KO) [BR:pvp00001]  09160 Human Diseases   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     105290755 (TOP2B)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:pvp03032]     105290755 (TOP2B)    03036 Chromosome and associated proteins [BR:pvp03036]     105290755 (TOP2B) Enzymes [BR:pvp01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.2  DNA topoisomerase (ATP-hydrolysing)      105290755 (TOP2B) DNA replication proteins [BR:pvp03032]  Eukaryotic type   DNA Topoisomerases    105290755 (TOP2B) Chromosome and associated proteins [BR:pvp03036]  Eukaryotic type   Chromosome condensation proteins    Other regulators of chromosome condensation     105290755 (TOP2B)   Centrosome formation proteins    Centriole proteins     105290755 (TOP2B) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  DNA_topoisoIV TOPRIM_C DNA_gyraseB DTHCT Toprim HATPase_c DUF7180 Microp_apicomplexa_20 Motif Other DBs NCBI-GeneID:  105290755 NCBI-ProteinID:  XP_011356482 UniProt:  A0A6P3Q3J5 LinkDB All DBs Position Unknown AA seq 1542 aa AA seqDB search MWVYDEDVGMNCRDITFVPGLYKIFDEILVNAADNKQRDKNMTCIKVSIDPESNIISIWN NGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDEEKKVTGGRNGYGAKLCNIFSTKFTVE TACKEYKHSFKQTWMNNMMKTSESKIKHFDGEDYTCITFQPDLSKFKMEKLDKDIVALMT RRVYDLAGSCKGVKVIFNGKKLPVNGFRSYVDLYVKDKLDETGVALKVIHELANERWDVC LTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKKNKAGVSVKPFQVKNHI WVFINCLIENPTFDSQTKENMTLQPKNFGSKCQLSEKFFKAASNCGIVESILNWVKFKAQ TQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDSAKSLAVSGLGVIGRDR YGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDDAESLKTLRYGKIMIMT DQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNKQELSFYSIPEFDEWKK HIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPEDDAAITLAFSKKKIDD RKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELILFSNSDNERSIPSLVD GFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQALMMTIVNLAQNFVGSNN INLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLARRLFPPVDDNLLKFLYDDNQRVEPEW YIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDGLDPHPMLPNYKNFKGTIQ ELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPMLNGTDKTPALISDYKEY HTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFDHMGCLKKYETVQDILK EFFDLRLSYYGLRREWLVGMLGAESAKLNNQARFILEKIQGKITIENRSKKDLIQMLVQR GYESDPVKAWKEAQEKATEEEETQNQHDDSSSDSGTPSGPDFNYILNMSLWSLTKEKVEE LIKQRDAKGREVNDLKRKSPSDLWKEDLAAFAEELDKVEAQEREDILAGMAGRTIKGKVG KPKVKKLQLDETMPSPYGRRIVPEITAMKADASKKLLKKKKGDLDTTTVKVEFDEEFSGT PVEGTGEEALIQSVPVNKGPKPKREKKEPGTRVRKTPTSSGKSSAKKVKKRNPWSDDESK SESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDNNDLEELKVKASPI TNDGEDEFVPSDGLDKDEYTFSPGKSKTTPEKSSHDKKSQDFGNLFSFPSYSQKSEDDSA KFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTTPKPKRTPKQKKVETINSD SDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTSKTPSKKPKKTSFDQDSDV DIFPSDFTSEPPSLPRTGRARKEVKYFAESDEEEDVDFAMFN NT seq 4629 nt NT seq  +upstreamnt  +downstreamnt atgtgggtgtatgatgaagatgtgggaatgaattgcagggatattacctttgtgccaggt ttatacaagatctttgatgaaatcttggttaatgcagctgacaataaacagagggataag aacatgacctgtattaaagtttctattgatcctgaatctaacattataagcatttggaat aatgggaaaggcattccagtggtagaacacaaagtagagaaagtttatgttccagcgtta atttttggacagcttttaacatccagtaactatgatgatgaggagaaaaaagtaacaggt ggtcgcaatggttatggtgcaaaactttgtaatattttcagtacaaagtttacagtagaa actgcttgcaaagaatacaaacatagttttaagcagacctggatgaataatatgatgaag acttctgaatccaaaattaaacatttcgatggtgaagattacacttgcataacattccaa ccagatctgtccaaatttaagatggaaaaacttgacaaggatattgtggctctcatgacc agaagagtttatgatctggctggttcatgcaaaggggtcaaggtcatatttaatggaaag aaattgcctgtaaatggatttcgcagttatgtagatctttatgtgaaagacaaattggat gaaactggagtggctctgaaagttattcatgaacttgcaaatgaaagatgggatgtttgt cttacattgagtgaaaaaggattccagcaaatcagctttgtaaatagtatcgcaacaaca aaaggtggacggcacgtggattatgtagtagatcaagttgttggtaaactgattgaagtg gtgaagaaaaagaacaaagctggtgtatcagtgaaaccatttcaagtaaaaaaccatata tgggtttttattaattgccttatcgaaaatccaacttttgattctcagactaaagaaaac atgactttgcagcccaaaaattttgggtccaaatgtcaactgtcagaaaaatttttcaaa gcagcctctaactgtggcattgtagaaagtatcctgaactgggtgaaatttaaggctcag actcagctgaacaagaagtgttcatcagtaaagtacagtaaaattaaaggtattcccaaa ctggatgatgctaatgatgctggtggcaaacattccctagagtgtacactgatactaaca gagggagactcagccaaatcactggctgtgtctggattaggtgtgatcgggcgagacaga tatggagtctttccactcaggggaaaaattcttaatgtacgagaagcttctcataaacag atcatggaaaatgcagaaataaacaatattattaaaatagttggtctacaatacaaaaaa agttatgatgatgcagaatctctgaaaactttacgctatggaaagattatgattatgact gatcaggatcaagatggttctcatataaaaggccttcttattaatttcatccatcacaat tggccatcacttttgaagcatggttttcttgaagagttcattactccaattgtaaaggca agcaaaaataagcaggaactttccttctacagtattcccgaatttgatgagtggaaaaaa catatagaaaaccagaaagcctggaaaataaaatactacaaaggattgggtaccagtaca gctaaagaagcaaaggaatattttgctgatatggaaaggcaccgcatcttgtttagatat gctggtcctgaagatgatgctgccattaccttggcgttcagtaaaaagaagatcgatgac agaaaagaatggttaacaaattttatggaagaccggagacagcgtaggttacatggctta ccagagcaatttttatatggtacagcgacaaagcatttgacgtacaatgatttcatcaac aaggaattgattctcttctcaaattcagacaatgaaagatctataccatctcttgttgat ggctttaaaccaggccaacgaaaagttttatttacctgtttcaagagaaacgataaacgt gaagtaaaagttgcccagttggctggatctgttgctgagatgtctgcttatcatcatgga gaacaagcattgatgatgactattgtgaatttggctcagaactttgtgggaagtaacaac attaacttgcttcagcctattggtcagtttggaactcggcttcatggtggcaaagatgct gcaagcccgcgttatattttcaccatgttaagctctttagcaaggcggctttttcctcct gtggatgataacctgcttaaattcctgtatgatgataatcaacgtgtagagcctgagtgg tatattcccataatccccatggttttaataaatggtgctgagggcattggtactggatgg gcttgtaaactacccaactatgatgctagggaaattgtgaacaatgtcagacgaatgcta gatggcttggatcctcatcccatgcttccaaactacaaaaactttaaaggaacgatccaa gaacttggtcaaaaccaatatgcagtcagtggtgaaatatttgtggtggatagaaacaca gtagagattacagagcttccagttagaacttggacacaggtatacaaagaacaagtttta gaacctatgctaaatggaacagataaaacaccagcattaatttctgattataaagaatat catactgacacaactgtgaaatttgtggtgaaaatgactgaagagaaactagcacaagca gaagctgctggactgcacaaagtttttaagcttcaaactactcttacttgtaattccatg gtactctttgatcatatgggctgtctgaagaagtatgaaactgtacaggacattttgaaa gaattctttgatttacgactaagttattatggtttacgtagggagtggcttgtagggatg ttgggagcagaatctgcaaagcttaacaatcaagctcgtttcattttagagaagatacaa ggaaaaattactatagagaataggtcaaagaaagatttgattcaaatgttagtccagaga ggttatgaatctgacccagtgaaagcctggaaagaagcacaagaaaaggcaacagaagag gaagaaacacaaaaccagcatgatgatagttcctctgattcaggaactccttcaggccct gattttaattatattttaaatatgtctctgtggtctcttactaaagaaaaagttgaagaa ttgattaaacagagagatgcgaaaggacgagaggtcaatgatcttaaaagaaaatctcct tcagatctttggaaagaagatttagcagcatttgctgaagaactggataaagtggaagct caagaacgagaagatattctggctggaatggctggaagaacaataaaaggtaaagttggc aaacctaaggtgaagaaacttcagttggatgagactatgccctcaccttatgggaggaga atcgttcccgaaatcactgctatgaaggcagatgccagcaaaaagttgttgaagaagaaa aagggcgatcttgataccacaacagtaaaagtggaatttgatgaagaattcagtggaaca ccagtagaaggtacaggcgaagaggcattgatacagtcagtgcctgtaaataaaggtccc aaacccaaaagggagaagaaggagcctggtaccagggtgagaaaaacacctacatcatct ggtaaatctagtgcaaagaaagtgaagaaacggaatccttggtcagatgatgaatccaag tcagaaagcgacttggaagaaacagaacctgtggttattccaagagattctttgcttagg agagcggctgctgaaaggcctaagtacacgtttgatttctcagaagaagaggatgatgat gctgatgatgatgatgacaataacgatttagaggaattaaaagttaaagcatctcccata acaaatgatggagaagatgagtttgttccttcagatggcctagataaagatgaatataca ttttcaccaggcaaatctaaaactactccagaaaaatcttcgcatgataaaaaaagtcag gattttgggaatcttttctcatttccttcatactctcagaagtcagaagatgattcagct aaatttgacagtaatgaagaagattctgcttctgttttttcaccgtcatttggtctgaaa caaacagataaagtaccaagtaaaacagtagctgctaaaaaaggaaaaccatcttcagat acaacccctaagcccaagagaactcccaaacagaagaaagtagagactataaactctgac tcagattcagaatttggcattccaaagaagactacaacaccaaaaggtaaaggccgaggg gcaaagaaaaggaaagcatctggctctgaaaatgaaggtgattataaccctggcaggaaa acatccaaaacaccaagcaagaaaccgaagaaaacatcttttgatcaggattcggatgtg gacatcttcccatcagacttcacttctgaaccaccttctctgccacggacgggtcgggct aggaaagaagtaaaatattttgcagagtctgatgaagaagaagatgttgattttgcaatg tttaattaa

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