Pteropus vampyrus (large flying fox): 105294112
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Entry
105294112 CDS
T07815
Symbol
ITPR2
Name
(RefSeq) inositol 1,4,5-trisphosphate receptor type 2
KO
K04959
inositol 1,4,5-triphosphate receptor type 2
Organism
pvp
Pteropus vampyrus (large flying fox)
Pathway
pvp04020
Calcium signaling pathway
pvp04022
cGMP-PKG signaling pathway
pvp04070
Phosphatidylinositol signaling system
pvp04114
Oocyte meiosis
pvp04210
Apoptosis
pvp04218
Cellular senescence
pvp04270
Vascular smooth muscle contraction
pvp04371
Apelin signaling pathway
pvp04380
Osteoclast differentiation
pvp04540
Gap junction
pvp04611
Platelet activation
pvp04621
NOD-like receptor signaling pathway
pvp04625
C-type lectin receptor signaling pathway
pvp04720
Long-term potentiation
pvp04723
Retrograde endocannabinoid signaling
pvp04724
Glutamatergic synapse
pvp04725
Cholinergic synapse
pvp04726
Serotonergic synapse
pvp04728
Dopaminergic synapse
pvp04730
Long-term depression
pvp04750
Inflammatory mediator regulation of TRP channels
pvp04912
GnRH signaling pathway
pvp04915
Estrogen signaling pathway
pvp04918
Thyroid hormone synthesis
pvp04921
Oxytocin signaling pathway
pvp04922
Glucagon signaling pathway
pvp04924
Renin secretion
pvp04925
Aldosterone synthesis and secretion
pvp04927
Cortisol synthesis and secretion
pvp04928
Parathyroid hormone synthesis, secretion and action
pvp04929
GnRH secretion
pvp04934
Cushing syndrome
pvp04935
Growth hormone synthesis, secretion and action
pvp04970
Salivary secretion
pvp04971
Gastric acid secretion
pvp04972
Pancreatic secretion
pvp05010
Alzheimer disease
pvp05012
Parkinson disease
pvp05017
Spinocerebellar ataxia
pvp05020
Prion disease
pvp05022
Pathways of neurodegeneration - multiple diseases
pvp05163
Human cytomegalovirus infection
pvp05167
Kaposi sarcoma-associated herpesvirus infection
pvp05170
Human immunodeficiency virus 1 infection
pvp05205
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:
pvp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
105294112 (ITPR2)
04020 Calcium signaling pathway
105294112 (ITPR2)
04070 Phosphatidylinositol signaling system
105294112 (ITPR2)
04022 cGMP-PKG signaling pathway
105294112 (ITPR2)
09140 Cellular Processes
09143 Cell growth and death
04114 Oocyte meiosis
105294112 (ITPR2)
04210 Apoptosis
105294112 (ITPR2)
04218 Cellular senescence
105294112 (ITPR2)
09144 Cellular community - eukaryotes
04540 Gap junction
105294112 (ITPR2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
105294112 (ITPR2)
04621 NOD-like receptor signaling pathway
105294112 (ITPR2)
04625 C-type lectin receptor signaling pathway
105294112 (ITPR2)
09152 Endocrine system
04922 Glucagon signaling pathway
105294112 (ITPR2)
04929 GnRH secretion
105294112 (ITPR2)
04912 GnRH signaling pathway
105294112 (ITPR2)
04915 Estrogen signaling pathway
105294112 (ITPR2)
04921 Oxytocin signaling pathway
105294112 (ITPR2)
04935 Growth hormone synthesis, secretion and action
105294112 (ITPR2)
04918 Thyroid hormone synthesis
105294112 (ITPR2)
04928 Parathyroid hormone synthesis, secretion and action
105294112 (ITPR2)
04924 Renin secretion
105294112 (ITPR2)
04925 Aldosterone synthesis and secretion
105294112 (ITPR2)
04927 Cortisol synthesis and secretion
105294112 (ITPR2)
09153 Circulatory system
04270 Vascular smooth muscle contraction
105294112 (ITPR2)
09154 Digestive system
04970 Salivary secretion
105294112 (ITPR2)
04971 Gastric acid secretion
105294112 (ITPR2)
04972 Pancreatic secretion
105294112 (ITPR2)
09156 Nervous system
04724 Glutamatergic synapse
105294112 (ITPR2)
04725 Cholinergic synapse
105294112 (ITPR2)
04728 Dopaminergic synapse
105294112 (ITPR2)
04726 Serotonergic synapse
105294112 (ITPR2)
04720 Long-term potentiation
105294112 (ITPR2)
04730 Long-term depression
105294112 (ITPR2)
04723 Retrograde endocannabinoid signaling
105294112 (ITPR2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
105294112 (ITPR2)
09158 Development and regeneration
04380 Osteoclast differentiation
105294112 (ITPR2)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
105294112 (ITPR2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
105294112 (ITPR2)
05163 Human cytomegalovirus infection
105294112 (ITPR2)
05167 Kaposi sarcoma-associated herpesvirus infection
105294112 (ITPR2)
09164 Neurodegenerative disease
05010 Alzheimer disease
105294112 (ITPR2)
05012 Parkinson disease
105294112 (ITPR2)
05017 Spinocerebellar ataxia
105294112 (ITPR2)
05020 Prion disease
105294112 (ITPR2)
05022 Pathways of neurodegeneration - multiple diseases
105294112 (ITPR2)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
105294112 (ITPR2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
pvp04040
]
105294112 (ITPR2)
Ion channels [BR:
pvp04040
]
Ligand-gated channels
IP3 receptor
105294112 (ITPR2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RYDR_ITPR
Ins145_P3_rec
MIR
RIH_assoc
Ion_trans
Sec2p
Mis12
Motif
Other DBs
NCBI-GeneID:
105294112
NCBI-ProteinID:
XP_011361472
UniProt:
A0A6P3QBR8
LinkDB
All DBs
Position
Unknown
AA seq
2488 aa
AA seq
DB search
MSDKMSSFLYIGDIVSLYAEGSVNGFISTLGLVDDRCVVHPEAGDLANPPKKFRDCLFKV
CPMNRYSAQKQYWKAKQAKQGNHTEAALLKKLQHAAELEQKQNESENKKLLGEIVKYSNV
IQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDAAGNEGSWFYIHPFWKLRSEGDNVVHHD
PCRGGAGQWNSLFRFKHLATGNYLAAELNPDYRDAQNEGKNVRDGDLPTSKKKRQAGEKI
MYTLVSVPHGNDIASLFELDATTLQRADCLVPRNSYVRLRHLCTNTWVTSTSIPIDTDEE
RPVMLKIGTCQTKEDKEAFAIVSVPLSEVRDLDFANDANKVLATTVKKLENGTITQNERR
FVTKLLEDLIFFVADVLNNGQEVLDVVITKPNRERQKLMREQNILAQVFGILRAPFKEKA
GEGPMLRLEDLGDQRYAPYKYMLRLCYRVLRHSQQDYRKNQEYIAKNFCVMQSQIGYDIL
AEDTITALLHNNRKLLEKHITAKEIETFVSLLRRNREPRFLDYLSDLCVSNTTAIPVTQE
LICKFMLSPGNADILIQTKLVSMQVDNPMESSILTDDIDDEEVWLYWIDSNKEPHGKAIR
HLAQEAKEGTKADLEVLTYYRYQLNLFARMCLDRQYLAINQISTQLSVDLILRCVSDESL
PFDLRASFCRLMLHMHVDRDPQESVVPVRYARLWTEIPTKITIHEYDSITDSSRNDMKRK
FALTMEFVEEYLKEVVNQPFPFGDKEKNKLTFEVVHLARNLIYFGFYSFSELLRLTRTLL
AILDIVQTPMSSYFERLSKFQDGGNNVMRTIHGVGEMMTQMVLSRGSIFPVSVPDVQPSL
HPSKQGSPTEHEDVTVMDTKLKIIEILQFILSVRLDYRISYMLSIYKKEFGENNENAETS
ANGSPDTLLPSAIVPDIDEIASQAETMFAGRKEKNPVQLDDEGGRTFLRVLIHLIMHDYP
PLLSGALQLLFKHFSQRAEVLQAFKQVQLLVSNQDVDNYKQIKADLDQLRLTVEKSELWV
EKSSSYENGEIGENQVKGGEEPIEESNILSPVQDGTKKPQIDSNKSNNYRIVKEILIRLS
KLCIQNKKCRNQHQRLLKNMGAHSVVLDLLQIPYEKNDEKMNEVMNLAHTFLQNFCRGNP
QNQVLLHKHLNLFLTPGLLEAETMRHIFMNNYHLCNEISERVVQHFVHCIETHGRHVEYL
RFLQTIVKADGKYVKKCQDMVMTELINGGEDVLIFYNDRASFPILLQMMCSERDRGDESG
PLAYHITLVELLAACTEGKNVYTEIKCNSLLPLDDIVRVVTHDDCIPEVKIAYVNFVNHC
YVDTEVEMKEIYTSNHIWKLFENFLVDMARVCNTTTDRKHADTFLEKCVTESIMNIVSGF
FNSPFSDNSTSLQTHQPVFIQLLQSAFRIYNCTWPNPSQKASVESCIRTLAEVAKNRGIA
IPVDLDSQVNTLFMKSHSNMVQRAAMGWRLSARSGPRFKEALGGPAWDYRNIIEKLQDVV
ASLEQQFSPMMQAEFSVLVDVLYSPELLFPEGSDARIRCGAFMSKLINHTKKLMEKEEKL
CIKILQTLREMLEKKDSFVEEGSTLRKILLNRYFKGDYGVGMNGHLSGTYCKSAQGGGSF
SGQDSDKMGISMSDIQCLLDKEGASELVIDVIVNTKNDRIFSEGILLGIALLEGGNTQTQ
YSFYQQLHEQKKSEKFFKVLYDRMKAAQKEIRSTVTVNTIDLGNKKRDDDNELMTSGPRM
RVRDSSLHLKEGMKGQLTEASSATSKAYCVYRREMDPEIDIMCSGSEAGNAEDKSAEEVT
MSPAIAIMQPILRFLQLLCENHNRELQNFLRNQNNKTNYNLVCETLQFLDCICGSTTGGL
GLLGLYINEKNVVLVNQTLESLTEYCQGPCHENQTCIATHESNGIDIIIALILNDINPLG
KYRMDLVLQLKNNASKLLLAIMESRHDSENAERILFNMRPRELVDVMKNAYNQGLECDHG
DDEGGDDGVSPKDVGHNIYILAHQLARHNKLLQQMLKPGSDPDDGDEALKYYANHTAQIE
VSIYYFSKGTNCNPALFWFSRHISLWGSISFNLAVFINLAVALFYPFGDDGDEGTLSPLF
SVLLWIAVAICTSMLFFFSKPVGIRPFLVSVMLRSIYTIGLGPTLILLGAANLCNKIVFL
VSFVGNRGTFTRGYRAVILDMAFLYHVAYVLVCMLGLFVHEFFYSFLLFDLVYREETLLN
VIKSVTRNGRSIILTAVLALILVYLFSIIGFLFLKDDFTMEVDRLKNRTPITGSNDISTM
TLSSMMKTCDKENCSPTIPASNTADEEYEDGIERTCDTLLMCIVTVLNQGLRNGGGVGDV
LRRPSKDFLCFAGLERDKFDNKTVSFEEHIKSEHNMWHYLYFLVLVKVKDPTEYTGPESY
VAQMIVEKNLDWFPRMRAMSLVSNEGDSEQNEIRNLQEKLESTMSLVKQLSGQLAELKEQ
MTEQRKNKQRLGFLGSNTPHVNHHMPPH
NT seq
7467 nt
NT seq
+upstream
nt +downstream
nt
atgtctgataaaatgtccagcttcctctacataggggacatcgtgtccctgtacgcggag
ggctcggtcaacggcttcatcagcaccctggggttagtggatgatcggtgcgtggtgcac
ccagaagcaggagaccttgccaaccctcccaagaagttcagagactgcctctttaaggta
tgtcctatgaatcgatattctgcccagaaacaatattggaaagctaagcaagccaaacaa
gggaaccacacagaggcagccttgctgaagaaattacagcatgctgcagaactggaacaa
aagcaaaatgaatcagaaaataagaaactgttgggagaaattgtgaaatacagtaatgtt
atacaactactgcatatcaaaagcaacaagtatctgactgtcaacaagagattacctgct
ttactggagaagaatgccatgcgtgtgtccttggatgctgcaggaaatgaaggatcttgg
ttttatattcatcccttctggaagctgagaagtgagggtgacaatgtggttcatcatgac
ccgtgccgtgggggtgcaggacaatggaacagcttgttcagatttaaacatcttgctact
gggaactatttagctgcagagcttaatcctgattatcgagatgcccaaaatgaaggaaaa
aatgtgagagatggagatcttccaacttcaaagaagaaacgccaggcaggggagaagatc
atgtacaccttggtctcagtcccacatggaaatgacattgcgtctctttttgaattggat
gccacaactcttcagagagctgactgcctggttccaaggaactcatatgttcggttaaga
catttatgtaccaacacatgggtaaccagtacgagtatccccatagacacagatgaagag
aggcctgttatgttgaagattggaacttgccagaccaaagaagacaaagaagcatttgcc
attgtgtccgtcccgctgtccgaggtccgagacttagattttgccaatgatgcaaataaa
gtgctggcgaccacagttaaaaagctggaaaatggcacaataactcagaatgaaaggagg
tttgtaaccaaattattggaggacctcatcttctttgtcgctgatgtacttaataatgga
caagaagttctggatgtggttatcactaagccaaaccgagaacgtcagaaattaatgaga
gaacaaaacatattggcacaggtatttgggattcttagagcaccctttaaggagaaagca
ggagaaggcccaatgctgaggcttgaagatctgggagaccaaagatatgctccctacaaa
tacatgctgaggctctgctaccgtgtgctgagacattcacagcaggactaccggaaaaat
caggaatatattgctaagaacttctgtgtcatgcagtcccagattggctatgatattttg
gcagaagataccatcacagctttgttgcacaacaacagaaaactactagagaaacatatc
acagcaaaagaaatagaaacatttgtcagtttgctcaggagaaaccgtgagccaagattc
ttggattatttatcagatctgtgtgtgtctaataccactgctatacctgtaactcaagaa
ctcatctgtaaattcatgttgagcccaggcaatgcagacattctcattcaaactaaactg
gtttcgatgcaagtggacaaccccatggagagctccatccttacagatgacattgatgat
gaggaagtttggctctactggattgacagcaacaaagaacctcatggcaaagctattagg
caccttgctcaagaagcaaaagaaggcaccaaagccgacttagaagttcttacgtattac
aggtatcagctaaacctctttgcaaggatgtgcttggatcgccagtatctggccatcaac
cagatttctacgcagctctctgttgatttgatcctgcgatgtgtgtcggatgagagcctg
ccatttgacctccgagcatctttttgtcgcctcatgctccacatgcatgttgaccgggat
ccccaagagtccgtggtgcctgttcgttatgccaggctctggacagaaatccccacaaag
atcacgattcatgaatatgattctataacagactcttccagaaatgatatgaagaggaaa
tttgcactgacaatggaatttgttgaagaatacttgaaagaagttgtaaatcagcctttt
ccttttggggataaagaaaaaaacaaactgacatttgaggtggtccacttggctcggaat
ctcatatactttggattttatagtttcagtgagttattaaggctaacaagaacacttctg
gctatcctagatattgtacagacccccatgtcatcgtattttgaaagattaagcaaattt
caagatggaggaaacaatgtcatgagaaccattcatggggtgggagagatgatgacccag
atggtgctcagtagaggctctatcttccctgtgagtgtgcctgatgttcagcccagcctc
caccccagcaagcaagggagccccactgagcatgaggacgtgaccgtgatggacaccaaa
ctgaagattattgagattttacagtttatccttagtgtcagactagattatcggatctca
tatatgctatccatatataagaaggaattcggagagaacaacgagaatgctgaaacatct
gcaaatggctctccagacacattactcccatcagctattgttcctgatatagatgaaatt
gcatctcaggcagaaactatgtttgctggaagaaaagagaaaaatccagttcaacttgat
gatgaaggaggcaggacgtttttacgggtccttattcatctgatcatgcatgactatcct
cctttgctatcaggagccctgcagcttctgttcaagcacttcagccagagagcagaagtt
ttacaggcatttaaacaggtgcaattgctggtgtccaatcaagatgtagataactacaag
caaataaaggcagatctagaccagcttcgactaactgtagaaaaatctgagttatgggtt
gagaagagtagcagctatgagaatggagaaataggtgaaaatcaagtaaaaggtggtgaa
gagccaattgaggaatcaaacattttaagtccagtgcaggacggaacaaagaaaccacag
attgacagcaataagagcaataactaccggattgtaaaggagattttgattaggctaagt
aaactgtgtatacagaataaaaagtgtcggaatcaacatcaacgattactgaaaaatatg
ggagctcattcagtggtgttggatcttctgcagataccctatgaaaagaatgatgaaaag
atgaatgaagtaatgaacctggcccatacattcctgcagaatttctgtcggggaaaccca
cagaatcaagttctccttcataaacatctgaatttgtttttaactcctgggctccttgaa
gcagaaaccatgcggcacatcttcatgaacaattaccatctgtgcaatgaaatcagcgag
agagttgtgcagcatttcgtgcactgcattgagacacacggtcgccacgtggagtacctg
aggtttttgcaaacgattgtaaaagcagatggtaaatatgtgaagaaatgccaggatatg
gtaatgacagagttgataaacgggggtgaagatgtgctgatattttacaatgatagagca
tcatttcccatccttctccaaatgatgtgttcagagagagaccggggggatgagagtggt
cctctagcctaccacatcacccttgtggagttgctggctgcgtgtacagaggggaaaaac
gtctacactgaaatcaagtgcaattcccttctgcccctggacgacatagtgagggtggtg
acgcatgatgactgcatccctgaggttaaaattgcatatgtgaatttcgttaatcactgt
tatgttgacactgaagtggaaatgaaagaaatttacacaagcaaccacatctggaaatta
tttgagaacttcttggtggatatggcaagggtttgcaacacaaccacagacaggaagcat
gcagacaccttcttggagaagtgtgttactgagtcaataatgaacattgtgagcggcttc
tttaattctcctttttcagacaacagtaccagcctccagacacatcagccagtttttatt
cagctactgcaatctgccttcagaatttacaattgtacctggccaaacccgtcacagaaa
gcttcagtggagtcttgtatcagaaccttggctgaagtggcaaagaatcgtggaattgct
attccagtggatttggacagccaagttaatactcttttcatgaagagccattcaaatatg
gtgcagagagcagccatgggttggagactatccgctcgctctggaccacgctttaaggaa
gctctcggagggcctgcttgggattatagaaatattattgaaaagttacaggacgtggtg
gcctccttggagcaacaattcagcccgatgatgcaggctgagttctcagtgttggttgat
gtgttgtacagtccagaactactgttccctgaggggagtgatgcaagaatacgatgcggt
gctttcatgtccaagttgattaatcatacaaagaaactaatggagaaagaagaaaaactg
tgcattaaaattcttcagactttacgagaaatgctagagaagaaagacagctttgtggaa
gagggtagcacattaagaaaaatactcctgaatcgatactttaaaggtgattatggagtt
ggtatgaatggacacctttctggaacctactgcaagtctgcacaagggggaggaagcttt
tctggacaagattcagataagatggggatatcaatgtcagatattcagtgtctgctggat
aaagaaggtgcatctgaacttgtcatcgatgttatagtgaacaccaaaaatgacagaatt
ttttcagaaggcattttacttggcattgcgttgctcgaaggaggaaatacgcaaactcag
tattctttttaccagcaattacatgaacaaaaaaagtcagaaaaattcttcaaagttcta
tatgaccgaatgaaggctgctcagaaagagataagatcaacagtgacagttaataccatc
gacttaggtaataaaaaaagggatgatgacaatgaattgatgacatctggtccccgaatg
agagtaagagattcatcattacatttaaaagaggggatgaaagggcaattaacagaagct
tcttcagcaacatccaaagcatactgtgtatacagaagagaaatggatccagaaatagac
attatgtgctcaggatcagaagcaggaaatgctgaggacaaatctgcagaggaagtaaca
atgagtcctgcaattgccatcatgcagccgatactgaggtttcttcagttactatgcgaa
aatcacaaccgagaattgcagaacttcttgaggaatcaaaacaacaaaacaaattacaac
cttgtctgtgagacccttcagtttttggactgcatttgtggaagtacaacgggaggcctg
ggcctgttgggtctctacatcaatgagaagaatgtagtgctggtcaaccagactctggaa
agcttgacggagtattgccaggggccgtgccatgaaaatcagacatgtattgctactcat
gaatccaatgggattgatatcatcattgctttgattctaaatgacataaaccctcttggt
aaatatcgaatggacctggtactccaactaaagaacaatgcttccaagcttttgctggcc
attatggaaagcagacatgacagtgagaatgcagaaagaattctttttaacatgagaccc
agggaactggtggacgtgatgaagaatgcctataaccaaggactggaatgtgatcacggg
gacgatgagggtggagacgatggcgtttccccaaaagatgttggacacaatatctacatt
ctggcccatcagttggcccgccacaacaaattattacagcagatgcttaaaccaggatca
gatccagatgacggagatgaagccttaaagtattatgccaaccatactgcacagattgaa
gtaagcatctattatttctcgaaaggaaccaattgtaaccctgccctgttctggttctcg
aggcacatatctctctggggaagcatttccttcaacttggctgtgtttatcaacttagct
gttgctctcttctacccatttggggatgatggagatgaaggtacactttctccattgttc
tcagttcttctttggatagcagttgcaatctgcacatctatgctgtttttcttctccaag
cctgtgggtattcggccatttcttgtgtcagtaatgctcagatctatatatacaataggt
cttgggcctacattaatacttcttggcgcagctaatctttgtaataaaatagtgtttctg
gtgagttttgtcggaaatcgtggcacgttcacccgaggataccgagcggtcattctggat
atggcctttctctaccacgtagcatatgtcctggtctgcatgctgggcctctttgtccat
gaattcttctatagctttctgctttttgatttggtgtacagagaagagactctgcttaat
gttataaagagtgtcacgcggaatggccgctccattattctaactgcagtcctcgctctc
atccttgtctacctgttttccattattggattcctttttctgaaagatgacttcactatg
gaagtggataggctgaaaaacagaactcccattacaggaagtaatgacatttctactatg
actttaagttcaatgatgaaaacatgtgacaaggaaaactgctcacctacgataccagct
tcaaatacagctgatgaagagtatgaagacggaattgaaaggacatgtgacactcttctt
atgtgcattgtcactgttctgaaccagggcctcaggaatggaggtggtgtgggagacgtg
ctgagaaggccatccaaagatttcctgtgttttgcaggactcgagagggacaagtttgat
aataaaactgtttcatttgaggagcacatcaagtcagaacacaatatgtggcattatttg
tacttcctagtcttggtgaaggttaaagaccccactgaatacactggacctgaaagttat
gtggctcaaatgattgtggagaagaatttggactggtttcctcggatgcgagccatgtcc
cttgttagcaatgaaggtgacagtgagcaaaatgaaattcggaacctgcaggagaagttg
gaatctaccatgagtctggtcaaacagctgtcgggtcagctggcagagctcaaggagcag
atgacagaacaaaggaagaataagcagagactgggctttctcggatcaaacacaccccat
gtgaatcatcacatgccaccacactga
DBGET
integrated database retrieval system
