Pteropus vampyrus (large flying fox): 105295844
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Entry
105295844 CDS
T07815
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
pvp
Pteropus vampyrus (large flying fox)
Pathway
pvp00230
Purine metabolism
pvp00670
One carbon pool by folate
pvp01100
Metabolic pathways
pvp01523
Antifolate resistance
Module
pvp_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
pvp00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
105295844 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
105295844 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
105295844 (GART)
Enzymes [BR:
pvp01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
105295844 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
105295844 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
105295844 (GART)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
ATP-grasp_2
CPSase_L_D2
Dala_Dala_lig_C
ATP-grasp_3
ATP-grasp_4
RimK
ATP-grasp_5
SNF5
Motif
Other DBs
NCBI-GeneID:
105295844
NCBI-ProteinID:
XP_011363971
UniProt:
A0A6P3QW00
LinkDB
All DBs
Position
Unknown
AA seq
1010 aa
AA seq
DB search
MAARVLVIGNGGREHTLAWKLAQSDHVKQVLVTPGNAGTACSEKISNAAISISDHSALAQ
FCKDEEIEFVVVGPEAPLAAGIVGNLTSAGVRCFGPTAEAAQLESSKRFAKEFMDRHGIP
TAQWRAFTKPEEACSFIMSASFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQDKAF
GAAGETVIIEELLEGEEVSCLCFTDGRTVAPMPPAQDHKRLLEGDHGPNTGGMGAYCPVP
QVSKDLLLKIKNIILQRTVDGMQQEGTPYTGVLYAGIMLTKDGPRVLEFNCRFGDPECQV
ILPLLKTDLYEVIQSTLDGLLCTSLPVWLENHTAITIVMASKGYPGDYTKGVEITGFSEA
QALGLEVFQAGTALKDGKVVTNGGRVLTVTAIQENLISALKEAKKGLAAIKFEGAIYRRD
IGYRAIAFLQQPRGLTYKESGVDIAAGNMLVRKIKHLAKATSRPGCDVDLGGFAGLFDLK
AAGFKDPLLACGTDGVGTKLKIAQQCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFAC
GKLDLDTTEAVVAGIAKACGKAGCALLGGETAEMPDMYTPGEYDLAGFAVGAMERHQKLP
HLERIAEGDVVIGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGDQTLGDLLLTPTR
IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPQKFAVDLDAQTWRIPRIFSWLQQEG
QLSEEEMARTFNCGIGAALVVSKDVTKQILKDIQQHQEEAWVIGRVVACPEGSPRVKVRH
LIEAMQINGSVLENGTLKSHFTAQPKKARVAVLISGTGSNLQALIDSTREPSSCAHIVVV
VSNKAAVAGLDKAARAGIPTRVINHNLYKSRVEFDTAIDQVLEEFSTDIVCLAGFMRILS
GPFVRKWNGKMLNIHPSLLPSFKGSNAHEQALGAGVKVTGCTVHFVAEEVDAGQIILQEA
VPVKRGDTVATLSERVKSAEHKIFPAALQLVASGTVWLGENGKLCWVKEK
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagtacttgtaattggcaatggaggaagagaacatacactggcttggaaa
cttgcacagtctgatcatgttaaacaggtgttggttaccccaggaaatgcaggcactgcc
tgctctgaaaagatttcaaatgctgccatctccatcagtgatcacagcgcccttgctcaa
ttctgcaaagatgaggaaattgaatttgtagttgttggaccagaggcacctctggctgct
ggaattgttgggaacctgacatctgcaggagtgcgatgctttggccccacagcagaagcg
gctcagttagagtccagcaaaagatttgccaaggagtttatggatcgacatggaatccca
actgcacaatggagagctttcaccaaacctgaagaggcctgcagcttcattatgagtgcc
agcttccctgctttggttgtgaaggccagtggtcttgcagctgggaaaggggtgattgtt
gcaaagagcaaagaagaggcctgcaaagctgtacaggagatcatgcaggataaagctttt
ggagcagctggagaaacagttatcattgaagaacttcttgaaggagaagaagtgtcttgt
ctgtgcttcactgatggaaggactgtggcccccatgcccccagcacaggaccataagcga
ttgctggaaggagatcacggccccaacactgggggaatgggagcctattgcccagtacct
caggtttctaaggatttgttgctaaaaattaaaaatatcattcttcagaggacagtggat
ggcatgcagcaggagggtacgccatacacaggtgttctctatgctggtataatgctgact
aaggatggcccaagagttctggagtttaattgccgtttcggtgatccagagtgccaagtc
atcctcccacttcttaaaactgatctttatgaagtgattcagtctaccttagatggcctg
ctgtgtacctctctgcctgtttggcttgaaaatcacactgctataactattgtcatggca
agtaaaggttatccaggagactacaccaagggtgtggagataacagggttttctgaggct
caggctttgggactggaggtgttccaagcaggtactgccctaaaagatggcaaagtggtg
actaatggtggtagagtccttacagtaacagccatccaggaaaatctcatctcagccctt
aaagaagccaagaaaggactagctgctataaagtttgagggagccatttacagacgggac
atcggctatcgtgccatagctttccttcagcagcccaggggcctgacttataaggaatct
ggggtagacattgcagctggaaatatgctggtcaggaaaattaaacatttagcaaaagcc
acctctagaccaggctgtgatgttgatcttggaggttttgctggtctttttgatttgaaa
gcagctggtttcaaagatcctcttttggcctgtggaacagatggtgttggaacaaaactg
aagattgcccagcagtgcaataaacatgataccattggtcaggatttggttgcaatgtgt
gtaaatgatattctggcacaaggagcagagcccctcttcttccttgattactttgcctgt
ggaaaacttgacctcgatacaactgaagcagttgttgctggaattgctaaagcctgtgga
aaagctggatgtgctctccttggtggcgaaacagcagaaatgcctgacatgtatactcca
ggagagtatgacctagccggttttgccgtcggtgccatggagcggcatcagaaactccct
catctggaaagaatcgccgaaggggatgttgtcattggaatagcttcatctggtcttcac
agcaatgggtttagcctcgtgaggaaaattgtagcgaaatcttcccttcagtactcctct
ccagcacccgatggctgcggtgaccagacattaggagacttgcttctaactccaaccaga
atctacagccattcactcttacctgtattacgttcaggacacgtcaaggcctttgcccac
attactggtggaggattgctagaaaacatccccagagtcctccctcagaaatttgcggtg
gatttagatgcccagacctggaggatccccaggatcttctcgtggttacagcaggaagga
cagctgtctgaagaagagatggccagaacatttaactgtgggattggggctgccctcgtg
gtatcaaaggacgtgacaaagcagattctgaaggatattcagcagcaccaggaagaagct
tgggtgattggcagggtggtggcatgccctgaaggttctcctcgtgtgaaagtcaggcac
ctaatcgaagccatgcagataaatggatcagtattggagaatggcaccctgaaaagccat
ttcactgcccaaccaaaaaaggcaagagtggctgtcttaatatctggaacaggatccaac
ctccaagctctgatagacagcactcgggagccgagcagctgtgcacacattgtcgtcgtc
gtctccaacaaagcggcggtggctggcttagataaagcagcgagagctggaattcctacc
agagtaattaatcataacttatataaaagtcgtgtagaatttgacactgcaattgaccaa
gtccttgaagagttctccacagacatagtctgtctcgcaggattcatgagaattttatcc
ggcccctttgtcagaaaatggaatgggaaaatgctcaacatccacccttccttgctccct
tcttttaagggttcaaatgcccacgagcaagccctgggtgccggtgtcaaagtaactggg
tgcacggtgcactttgtagctgaagaagtagatgctggacaaattattttgcaagaagct
gttcctgtgaagaggggtgacactgttgcaactctgtctgaaagagtgaaatcagcagag
cataaaatatttcccgcagccctccagctggtggccagtggaactgtgtggcttggagaa
aatggcaaactctgttgggttaaggagaaatga
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