KEGG   Pteropus vampyrus (large flying fox): 105297518
Entry
105297518         CDS       T07815                                 
Symbol
ADCY6
Name
(RefSeq) adenylate cyclase type 6 isoform X1
  KO
K08046  adenylate cyclase 6 [EC:4.6.1.1]
Organism
pvp  Pteropus vampyrus (large flying fox)
Pathway
pvp00230  Purine metabolism
pvp01100  Metabolic pathways
pvp01522  Endocrine resistance
pvp04015  Rap1 signaling pathway
pvp04022  cGMP-PKG signaling pathway
pvp04024  cAMP signaling pathway
pvp04062  Chemokine signaling pathway
pvp04072  Phospholipase D signaling pathway
pvp04081  Hormone signaling
pvp04082  Neuroactive ligand signaling
pvp04114  Oocyte meiosis
pvp04211  Longevity regulating pathway
pvp04213  Longevity regulating pathway - multiple species
pvp04261  Adrenergic signaling in cardiomyocytes
pvp04270  Vascular smooth muscle contraction
pvp04371  Apelin signaling pathway
pvp04540  Gap junction
pvp04611  Platelet activation
pvp04713  Circadian entrainment
pvp04714  Thermogenesis
pvp04723  Retrograde endocannabinoid signaling
pvp04724  Glutamatergic synapse
pvp04725  Cholinergic synapse
pvp04727  GABAergic synapse
pvp04742  Taste transduction
pvp04750  Inflammatory mediator regulation of TRP channels
pvp04911  Insulin secretion
pvp04912  GnRH signaling pathway
pvp04913  Ovarian steroidogenesis
pvp04914  Progesterone-mediated oocyte maturation
pvp04915  Estrogen signaling pathway
pvp04916  Melanogenesis
pvp04918  Thyroid hormone synthesis
pvp04921  Oxytocin signaling pathway
pvp04923  Regulation of lipolysis in adipocytes
pvp04924  Renin secretion
pvp04925  Aldosterone synthesis and secretion
pvp04926  Relaxin signaling pathway
pvp04927  Cortisol synthesis and secretion
pvp04928  Parathyroid hormone synthesis, secretion and action
pvp04934  Cushing syndrome
pvp04935  Growth hormone synthesis, secretion and action
pvp04961  Endocrine and other factor-regulated calcium reabsorption
pvp04962  Vasopressin-regulated water reabsorption
pvp04970  Salivary secretion
pvp04971  Gastric acid secretion
pvp04972  Pancreatic secretion
pvp04976  Bile secretion
pvp05032  Morphine addiction
pvp05163  Human cytomegalovirus infection
pvp05166  Human T-cell leukemia virus 1 infection
pvp05200  Pathways in cancer
pvp05207  Chemical carcinogenesis - receptor activation
pvp05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:pvp00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    105297518 (ADCY6)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    105297518 (ADCY6)
   04371 Apelin signaling pathway
    105297518 (ADCY6)
   04072 Phospholipase D signaling pathway
    105297518 (ADCY6)
   04024 cAMP signaling pathway
    105297518 (ADCY6)
   04022 cGMP-PKG signaling pathway
    105297518 (ADCY6)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    105297518 (ADCY6)
   04081 Hormone signaling
    105297518 (ADCY6)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    105297518 (ADCY6)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    105297518 (ADCY6)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    105297518 (ADCY6)
   04062 Chemokine signaling pathway
    105297518 (ADCY6)
  09152 Endocrine system
   04911 Insulin secretion
    105297518 (ADCY6)
   04923 Regulation of lipolysis in adipocytes
    105297518 (ADCY6)
   04912 GnRH signaling pathway
    105297518 (ADCY6)
   04913 Ovarian steroidogenesis
    105297518 (ADCY6)
   04915 Estrogen signaling pathway
    105297518 (ADCY6)
   04914 Progesterone-mediated oocyte maturation
    105297518 (ADCY6)
   04921 Oxytocin signaling pathway
    105297518 (ADCY6)
   04926 Relaxin signaling pathway
    105297518 (ADCY6)
   04935 Growth hormone synthesis, secretion and action
    105297518 (ADCY6)
   04918 Thyroid hormone synthesis
    105297518 (ADCY6)
   04928 Parathyroid hormone synthesis, secretion and action
    105297518 (ADCY6)
   04916 Melanogenesis
    105297518 (ADCY6)
   04924 Renin secretion
    105297518 (ADCY6)
   04925 Aldosterone synthesis and secretion
    105297518 (ADCY6)
   04927 Cortisol synthesis and secretion
    105297518 (ADCY6)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    105297518 (ADCY6)
   04270 Vascular smooth muscle contraction
    105297518 (ADCY6)
  09154 Digestive system
   04970 Salivary secretion
    105297518 (ADCY6)
   04971 Gastric acid secretion
    105297518 (ADCY6)
   04972 Pancreatic secretion
    105297518 (ADCY6)
   04976 Bile secretion
    105297518 (ADCY6)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    105297518 (ADCY6)
   04961 Endocrine and other factor-regulated calcium reabsorption
    105297518 (ADCY6)
  09156 Nervous system
   04724 Glutamatergic synapse
    105297518 (ADCY6)
   04727 GABAergic synapse
    105297518 (ADCY6)
   04725 Cholinergic synapse
    105297518 (ADCY6)
   04723 Retrograde endocannabinoid signaling
    105297518 (ADCY6)
  09157 Sensory system
   04742 Taste transduction
    105297518 (ADCY6)
   04750 Inflammatory mediator regulation of TRP channels
    105297518 (ADCY6)
  09149 Aging
   04211 Longevity regulating pathway
    105297518 (ADCY6)
   04213 Longevity regulating pathway - multiple species
    105297518 (ADCY6)
  09159 Environmental adaptation
   04713 Circadian entrainment
    105297518 (ADCY6)
   04714 Thermogenesis
    105297518 (ADCY6)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105297518 (ADCY6)
   05207 Chemical carcinogenesis - receptor activation
    105297518 (ADCY6)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    105297518 (ADCY6)
   05163 Human cytomegalovirus infection
    105297518 (ADCY6)
  09165 Substance dependence
   05032 Morphine addiction
    105297518 (ADCY6)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    105297518 (ADCY6)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    105297518 (ADCY6)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    105297518 (ADCY6)
Enzymes [BR:pvp01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     105297518 (ADCY6)
SSDB
Motif
Pfam: Guanylate_cyc AC_N Adcy_cons_dom HNOBA TBK1_ULD GBR2_CC
Other DBs
NCBI-GeneID: 105297518
NCBI-ProteinID: XP_023391193
UniProt: A0A6P6CWB5
LinkDB
Position
Unknown
AA seq 1198 aa
MSWFSGLLVPKVDERKTAWGECNGQKRPRHGTRTSGFCAPRYMSCLQDAQPPSPTPATPP
RCPWQEEAFIRRGGPGKGTELGLRAVALGFEDTETTALGAADVAPNVAPRSSRSCWRRLV
QVFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAVLVLLTAVLLTFHAAPAHPQPAYVAL
LACAAVLFVVLMVVCNRHSFRQDSMWVVSYVVLGILAAVQVGGALAANPHSPSVGLWCPV
FFVYITYTLLPIRMRAAVFSGLGLSTLHLILAWQLNRGDAFLWKQLGANMLLFLCTNVIG
ICTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINTKKE
DMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRI
KILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHCG
VLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGERNAYLK
EQHIETFLILGASQKRKEEKAMLAKLQRTRANSMEGLMPRWVPDRAFSRSKDSKAFRQMV
RAHSTRTWASLFCLPGSLSPAFVCLPCGCHFHGIDDSSKDNRGAQDALNPEDEVDEFLGR
AIDARSIDQLRKDHVRRFLLTFQREDLEKKYSRKVDPRFGAYVACALLVFCFICFIQLLV
FPHSTLMLGIYTGIFLLLLITMLTCAVYSCGSLFPKGLQHLSRSIVRSRAHSTAVGIFSV
LLVFTSAIANMFTCNHTSIRTCAARMLNLTPADITVCHLQQLNYSLGLDAPLCEGTVPTC
SFPEYFVGNMLLSLLASSVFLHISSIGKLAMIFVLGLIYLVLLLLGPPATIFDNYDLLLG
VHGLASSNETFDGLDCPAAGRVALKYMTPVILLVFALALYLHAQQVESTARLDFLWKLQA
TGEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSE
FYVELEANNEGVECLRLLNEIIADFDEIISEERFRQLEKIKTIGSTYMAASGLNASTYDQ
VGRSHITALADYAMRLMEQMKHINEHSFNNFQMKIGLNMGPVVAGVIGARKPQYDIWGNT
VNVSSRMDSTGVPDRIQVTTDLYQVLAAKGYQLECRGVVKVKGKGEMTTYFLNGGPSS
NT seq 3597 nt   +upstreamnt  +downstreamnt
atgtcatggttcagtggcctcctggtacccaaagtggatgaacggaaaacagcctggggg
gaatgcaatgggcagaagcgcccgcgtcatgggactcggaccagtggcttctgcgcaccc
cgctatatgagctgcctccaggatgcacagccacccagccccactcctgcaaccccacct
cggtgcccctggcaggaggaggccttcatccggaggggtggccctggcaagggcacagag
ctggggctgcgggccgtggccctgggctttgaggacactgagacaacagcacttggggca
gctgacgtggcacccaatgtggcacccaggagcagtcgatcctgttggcgccgtctggtt
caggtgttccagtcgaagcagttccgctcagccaagctagagcgcctgtaccagcggtac
ttcttccagatgaaccagagtagcttgacgctgctgatggcagtgcttgtgctgctcacg
gctgtgctgctgaccttccatgccgcgcctgcccacccccagcctgcctatgtggccctg
ctggcctgtgcggctgtcctctttgtggtgctcatggtggtgtgtaaccgacacagcttt
cgccaggactccatgtgggtggtgagctatgtggtgctgggcatcctggcagctgtgcag
gttgggggtgccctggcagccaacccccacagcccctccgtaggcctttggtgccctgtg
ttctttgtctacatcacctacactctcctacccatccgcatgcgggcagctgtcttcagt
ggcctgggcctctccaccctgcatttgatcttggcctggcaactcaaccgtggtgatgcc
ttcctctggaagcagctcggtgccaacatgctgctattcctctgcacgaatgtcattggc
atctgcacacactacccagctgaagtgtctcagcgccaggcctttcaggagacccgcggg
tacatccaggcccggctgcacctgcagcatgagaatcggcagcaggaacgcctgctgctg
tcagtgttgccccagcacgttgccatggagatgaaagaagacatcaacacaaagaaggaa
gacatgatgttccacaagatctacatccagaaacatgacaatgtcagcatcctgtttgca
gacattgaaggtttcaccagcctggcatcacagtgcactgcacaggagctggttatgacc
ctgaatgagctctttgcccggtttgacaagcttgctgcagaaaatcactgcctgaggatc
aagatcttaggggactgttactactgtgtgtcagggttgccggaggcccgggcagaccat
gcccactgctgtgtggagatgggggtggacatgattgaggccatctcgctggtgcgtgag
gtgacaggtgtgaacgtgaacatgcgcgtgggcatccacagtggacgtgtgcactgcggt
gtccttggtctgcggaagtggcaattcgatgtgtggtccaatgacgtgactctggccaac
cacatggaggcagggggccgggctggccgcatccacattactcgggccacgctgcagtac
ctgaacggggactacgaggtggagccagggcgtggcggtgagcgtaacgcgtacctcaag
gagcagcacattgagaccttcctgatccttggtgccagccagaaacggaaagaggagaaa
gccatgctggccaagctgcagcgaacgcgggccaactccatggaagggctgatgccacgc
tgggtgcctgaccgggctttctcccggagcaaggactccaaggcattccgccagatggtg
agggcccacagcacgaggacctgggcctcacttttttgtctccccggctctctgtcccct
gccttcgtctgccttccttgtggctgccatttccatggcattgatgattccagcaaagac
aaccggggcgcccaagatgccctgaaccctgaggatgaagtagacgagttcctgggccgt
gccatcgatgcccgcagcattgatcagctgcgcaaggaccatgtgcgccggttcctactc
acctttcagagagaggatcttgaaaagaagtactcaaggaaggtggatccccgcttcgga
gcctacgtggcctgtgccctgttggtcttctgcttcatctgcttcatccagctcctcgtc
ttcccacactcaacactgatgcttggaatctataccgggatctttctgctgctgttgatc
accatgctgacctgtgccgtgtactcctgtggctccctgttccctaagggcctgcaacat
ctatcacgtagcattgtgcgctctcgggcacacagcaccgctgttggcatcttttcagtc
ctgcttgtgtttacctccgccattgctaacatgttcacctgtaaccacacctccatacgg
acctgcgcagccaggatgctgaatttaacacctgctgacatcactgtctgccacctgcag
cagctcaattactctctgggcctggatgctcccctgtgtgagggcaccgtacccacctgc
agcttccccgagtacttcgtcgggaacatgctgctgagtctgttggccagctctgtcttc
ctgcacatcagtagcatcggaaagttggccatgatctttgtcttggggctcatctatttg
gtgctgcttctcctgggccccccagccaccatctttgacaactatgacctactgcttggt
gtccatggcttggcttcttctaatgagacttttgatgggctggactgcccagctgcaggg
agggtggcactcaaatatatgacccccgtgattctgctggtgtttgccctggccctgtat
ctgcatgctcagcaggtggaatcgactgcccgcctggacttcctctggaaactgcaggca
acaggggagaaggaggagatggaggagctccaggcatacaaccggcggctgttgcataac
attctgcccaaggatgtagctgcccacttcctggcccgggagcgccggaacgacgagctc
tactatcagtcgtgtgagtgtgtggctgtcatgtttgcctccattgccaacttctctgag
ttctacgtggagctggaggcaaataatgagggtgtggagtgcctgcggctgctcaacgag
attatcgctgattttgatgagatcatcagtgaggagcggttccggcagctggagaagatc
aagacgattggtagcacctacatggctgcctctgggctgaacgccagcacctatgatcag
gtgggccgctcccacatcaccgcccttgccgactatgccatgcggctcatggagcagatg
aagcacatcaatgagcactccttcaacaatttccagatgaagatcggactgaacatgggc
ccagttgtggcaggtgtcattggggctcggaagccacagtatgacatctgggggaacaca
gtgaatgtctctagccgtatggacagcacaggggtccctgacagaatccaggtgaccact
gacctgtaccaggttctggctgccaagggctaccagctggagtgtcgaggagtggtcaaa
gtgaagggcaagggggagatgaccacctacttcctcaatgggggccccagcagttag

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