Pteropus vampyrus (large flying fox): 105297760
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Entry
105297760 CDS
T07815
Symbol
ERN1
Name
(RefSeq) LOW QUALITY PROTEIN: serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
pvp
Pteropus vampyrus (large flying fox)
Pathway
pvp04140
Autophagy - animal
pvp04141
Protein processing in endoplasmic reticulum
pvp04210
Apoptosis
pvp04932
Non-alcoholic fatty liver disease
pvp05010
Alzheimer disease
pvp05012
Parkinson disease
pvp05014
Amyotrophic lateral sclerosis
pvp05016
Huntington disease
pvp05017
Spinocerebellar ataxia
pvp05022
Pathways of neurodegeneration - multiple diseases
pvp05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pvp00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
105297760 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
105297760 (ERN1)
09143 Cell growth and death
04210 Apoptosis
105297760 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
105297760 (ERN1)
05012 Parkinson disease
105297760 (ERN1)
05014 Amyotrophic lateral sclerosis
105297760 (ERN1)
05016 Huntington disease
105297760 (ERN1)
05017 Spinocerebellar ataxia
105297760 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
105297760 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
105297760 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
105297760 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pvp01001
]
105297760 (ERN1)
Enzymes [BR:
pvp01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
105297760 (ERN1)
Protein kinases [BR:
pvp01001
]
Serine/threonine kinases: Other
IRE family
105297760 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
105297760
NCBI-ProteinID:
XP_023391426
UniProt:
A0A6P6CV42
LinkDB
All DBs
Position
Unknown
AA seq
947 aa
AA seq
DB search
MSKVLAAASTPLLILGSPSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDPVLQVP
THVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMGKKQDIW
YVVDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYFDYAAS
LPEDDVDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRKVMHINV
AVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTXTRAVGRFSGLLGLPPGLTPVLSS
QPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKNKLNYLRNYWLLIGENG
GFSSPQVSHSLPYQVIHLVDQTSETAPTTVSQDVEEKFANAPAKPEAPMDSMLKDIATII
LSTFLLIGWVAFIITYPLSMHQQQQRQHQQFQKELEKIQLLQQQQLPFHAPGDVAPDAEL
LDSSGLYSESSGTSSPSTSPRASNHSLHSSGSASRTGASPFLEQDDEDEETSMVMVGKIS
FCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPECFSFADREVQLLRESDEHPNVIRYFC
TERDRQFQYIAIELCAATLQEYVEQKDFAHLGLEPITLLQQTTSGLAHLHSLNIVHRDLK
PHNILLSMPNAHGRIKAMISDFGLCKKLAVGRHSFSRRSGVPGTEGWIAPEMLSEDCKEN
PTCTVDIFSAGCVFYYVVSEGSHPFGKSLQRQANILLGAYSLDCLHSEKHEDVIARELIE
KMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFFQDVSDRIEKESLDGPIVKQLERGGRAVV
KMDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMRNKKHHYRELPAEVRETLGSLPDDFV
RYFTSRFPHLLSHTYRAMELCSHERLFQPYYFHPPPEPQPPVTPDAL
NT seq
2844 nt
NT seq
+upstream
nt +downstream
nt
atgagcaaggttctggcagctgcttcaacccctctgctgattttgggaagtcccagcaca
gtgactcttcctgaaaccctgttgttcgtgtcaaccctggatggaagtttgcatgctgtc
agcaagcggacaggctccatcaaatggactttaaaagaagatccagttctgcaggttcca
acccacgttgaagaacctgccttcctcccagatcccaatgatggcagcctgtacacactt
gggggcaagaataatgaaggcctgacgaaacttccctttacgatcccagagttggtacag
gcatccccgtgccgaagttcagatggaatcctctacatgggtaaaaagcaggacatttgg
tatgtggttgaccttctgaccggggagaagcaacagactttgtcatcagcctttgcagat
agtctctgcccatcaacctctcttctgtaccttggacgaacagagtacaccatcaccatg
tacgacaccaaaacccgagagctccggtggaacgccacctacttcgactatgcagcctcg
ctgcccgaggacgacgtggactataagatgtcccattttgtgtccaatggcgatgggctg
gtggtgactgtggacagtgaatctggcgacgtcctgtggatccaaaactacgcttcccct
gtggtggccttttatgtctggcagcgggagggtctgaggaaggtgatgcacatcaacgtc
gctgtggagaccctgcgctatctgaccttcatgtctggggaggtggggcgcatcaccaag
tggaagtaccccttccccaaggagacggaggccaagagcaagctgacgtgaactagagca
gttggccgtttctcagggcttcttggcttgcccccaggcctcaccccagttctgtcttca
cagccccgaggcagcactcttcctttgctggaaggcccccagaccgacggtgtcaccatt
ggggacaaaggggagtgtgtgatcacacccagcacggacctaaagtttgaccctgggctc
aaagggaagaacaagctcaactatttgaggaactactggcttctgataggtgagaacggg
ggtttctcttcgcctcaggtcagccactcgctcccctaccaggttatccacctggtggac
cagacctcagagactgcgcccaccaccgtttctcaggacgtggaggagaagttcgctaac
gcccccgccaagcctgaggcccccatggattccatgctcaaggacatagccaccatcatc
ctgagcaccttcctgctcatcggctgggtggccttcatcatcacctaccccttgagcatg
catcagcagcagcagcgccagcaccagcagttccagaaggaactggagaaaatccagctc
ctgcaacagcagcagctgcccttccacgcccccggggacgtggctccggacgccgagctc
ctggactcatctggcttgtattcggagagctcgggcaccagcagccccagcacgtccccc
agagcctccaaccactcgctgcactccagcggctctgcctccaggactggcgccagcccc
ttcctggagcaagatgacgaggacgaggaaaccagcatggtgatggttgggaaaatttca
ttctgccccaaggatgtcctgggccacggagcggagggcacaatcgtgtaccggggcatg
ttcgacaaccgtgacgtggcggtcaagcggatccttcccgagtgcttcagtttcgcagac
cgcgaggtccagctgctgcgagaatcagacgagcacccgaacgtgatccgttacttctgc
acggagagggaccgccagttccagtacattgccattgagctgtgcgcggccactctgcag
gagtacgtggagcagaaggactttgcccaccttggcctggagcccatcaccttgctgcag
cagaccacctcgggcctggcccacctgcactctctcaacattgttcacagagacctaaaa
ccccacaacatcctcctctccatgcccaacgcacatggcaggatcaaggccatgatctct
gactttggcctctgcaagaagctggcagtgggtaggcacagcttcagccgccgttcaggg
gtgcccggcacagaaggctggattgctccagagatgctgagtgaagactgtaaggagaac
cccacctgcacagtggacatcttctctgcgggctgtgtcttttactatgtggtgtccgag
ggcagccacccttttggcaagtccctgcagcggcaagcaaacatccttctgggcgcctac
agcctcgactgcttacactccgagaagcacgaagatgtcatcgccagggaattgatcgag
aagatgatcgcgatggaccctcagaagcgcccctcggcgaagcacgtgcttaaacacccg
ttcttctggagcctcgagaagcagctccagttctttcaggacgtgagtgaccgcatagag
aaggaatccctggatggcccgatcgtgaagcagctggagagaggcgggagagccgtggtg
aagatggactggagggagaacatcaccgtccctctccagacagatctgcgtaaattcaga
acctataaaggcggctctgtcagagatctcctccgagccatgagaaataagaagcaccac
taccgggagctccccgcagaggtaagggagaccctgggctccctccccgatgacttcgtg
cgctacttcacatcccgcttcccccatctgctctcacacacctaccgggccatggagctg
tgcagccacgagaggctcttccaaccctactacttccacccgcccccggagcctcagccc
ccagtgactccagacgccctctga
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