KEGG   Pteropus vampyrus (large flying fox): 105298936
Entry
105298936         CDS       T07815                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
pvp  Pteropus vampyrus (large flying fox)
Pathway
pvp04010  MAPK signaling pathway
pvp04015  Rap1 signaling pathway
pvp04218  Cellular senescence
pvp04380  Osteoclast differentiation
pvp04620  Toll-like receptor signaling pathway
pvp04664  Fc epsilon RI signaling pathway
pvp04668  TNF signaling pathway
pvp04750  Inflammatory mediator regulation of TRP channels
pvp04912  GnRH signaling pathway
pvp04935  Growth hormone synthesis, secretion and action
pvp04936  Alcoholic liver disease
pvp05014  Amyotrophic lateral sclerosis
pvp05022  Pathways of neurodegeneration - multiple diseases
pvp05132  Salmonella infection
pvp05135  Yersinia infection
pvp05145  Toxoplasmosis
pvp05161  Hepatitis B
pvp05163  Human cytomegalovirus infection
pvp05167  Kaposi sarcoma-associated herpesvirus infection
pvp05169  Epstein-Barr virus infection
pvp05170  Human immunodeficiency virus 1 infection
pvp05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pvp05417  Lipid and atherosclerosis
pvp05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pvp00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105298936 (MAP2K6)
   04015 Rap1 signaling pathway
    105298936 (MAP2K6)
   04668 TNF signaling pathway
    105298936 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    105298936 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    105298936 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    105298936 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    105298936 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    105298936 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    105298936 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    105298936 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    105298936 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    105298936 (MAP2K6)
   05161 Hepatitis B
    105298936 (MAP2K6)
   05163 Human cytomegalovirus infection
    105298936 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105298936 (MAP2K6)
   05169 Epstein-Barr virus infection
    105298936 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    105298936 (MAP2K6)
   05135 Yersinia infection
    105298936 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    105298936 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    105298936 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    105298936 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105298936 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    105298936 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    105298936 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pvp01001]
    105298936 (MAP2K6)
Enzymes [BR:pvp01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     105298936 (MAP2K6)
Protein kinases [BR:pvp01001]
 Serine/threonine kinases: STE group
  STE7 family
   105298936 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Choline_kinase Haspin_kinase CLP1_P DUF4344 APH
Other DBs
NCBI-GeneID: 105298936
NCBI-ProteinID: XP_011368708
UniProt: A0A6P3QYW1
LinkDB
Position
Unknown
AA seq 334 aa
MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSEEFVDFTSQCLKKNSK
ERPTYPELMQHPFFTLHESKATDVASFVKLIIGD
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaagaagcgaaaccctggccttaaaattccaaaggaagcattt
gaacagcctcagaccagttccacgccacctcgagatttagactccaaagcgtgcatttct
attggaaatcagaactttgaggtgaaggcggatgacctggaacctataatggagctggga
cgaggtgcgtacggggtggtggagaagatgcgacacgtgcccagcgggcagatcatggcg
gtgaagcggatccgggccacggtaaatagccaggagcagaaaaggctactgatggatttg
gatatttccatgaggacagtggactgtccttttacggtcaccttttatggcgcactcttc
cgggagggtgatgtttggatctgcatggagctcatggatacatcgctagataaattctac
aaacaagtgattgataaaggccaaacaattccagaggacatcttagggaaaatagcagtt
tctattgtaaaagcattagaacatttacacagtaagctgtctgtcattcatcgagatgtc
aagccttccaatgtgctgatcaatactctgggccaggtgaagatgtgcgattttggaatc
agtggctaccttgtagactccgtcgctaaaacgattgatgcaggatgcaaaccatacatg
gcccctgagagaataaacccagagctcaaccagaagggctacagcgtgaagtccgacatt
tggagtctgggcataacgatgattgagttggccatccttcggtttccctacgattcatgg
ggaactccctttcagcagctcaaacaagtagtagaggagccgtcgccacagctcccagca
gacaagttctccgaagagttcgttgactttacctcacagtgcttaaagaagaattccaaa
gaacggccaacgtatccagagcttatgcaacatccatttttcaccctacatgaatccaaa
gcaacagacgtggcatcttttgtaaaactgattattggagactaa

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