KEGG   Pteropus vampyrus (large flying fox): 105300315
Entry
105300315         CDS       T07815                                 
Symbol
FGFR1
Name
(RefSeq) fibroblast growth factor receptor 1 isoform X1
  KO
K04362  fibroblast growth factor receptor 1 [EC:2.7.10.1]
Organism
pvp  Pteropus vampyrus (large flying fox)
Pathway
pvp04010  MAPK signaling pathway
pvp04014  Ras signaling pathway
pvp04015  Rap1 signaling pathway
pvp04020  Calcium signaling pathway
pvp04151  PI3K-Akt signaling pathway
pvp04520  Adherens junction
pvp04550  Signaling pathways regulating pluripotency of stem cells
pvp04714  Thermogenesis
pvp04810  Regulation of actin cytoskeleton
pvp04928  Parathyroid hormone synthesis, secretion and action
pvp05200  Pathways in cancer
pvp05205  Proteoglycans in cancer
pvp05215  Prostate cancer
pvp05218  Melanoma
pvp05224  Breast cancer
pvp05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:pvp00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105300315 (FGFR1)
   04014 Ras signaling pathway
    105300315 (FGFR1)
   04015 Rap1 signaling pathway
    105300315 (FGFR1)
   04020 Calcium signaling pathway
    105300315 (FGFR1)
   04151 PI3K-Akt signaling pathway
    105300315 (FGFR1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    105300315 (FGFR1)
   04550 Signaling pathways regulating pluripotency of stem cells
    105300315 (FGFR1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    105300315 (FGFR1)
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    105300315 (FGFR1)
  09159 Environmental adaptation
   04714 Thermogenesis
    105300315 (FGFR1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105300315 (FGFR1)
   05205 Proteoglycans in cancer
    105300315 (FGFR1)
   05230 Central carbon metabolism in cancer
    105300315 (FGFR1)
  09162 Cancer: specific types
   05218 Melanoma
    105300315 (FGFR1)
   05215 Prostate cancer
    105300315 (FGFR1)
   05224 Breast cancer
    105300315 (FGFR1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pvp01001]
    105300315 (FGFR1)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:pvp04090]
    105300315 (FGFR1)
   00536 Glycosaminoglycan binding proteins [BR:pvp00536]
    105300315 (FGFR1)
Enzymes [BR:pvp01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     105300315 (FGFR1)
Protein kinases [BR:pvp01001]
 Receptor tyrosine kinases (RTK)
  FGFR family [OT]
   105300315 (FGFR1)
CD molecules [BR:pvp04090]
 Proteins
  105300315 (FGFR1)
Glycosaminoglycan binding proteins [BR:pvp00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   105300315 (FGFR1)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase I-set ig Ig_3 Ig_2 V-set C2-set_2 Ig_4 ABC1 V-set_CD47 Pkinase_fungal DUF1615 zf-CCCH_9
Other DBs
NCBI-GeneID: 105300315
NCBI-ProteinID: XP_011370774
UniProt: A0A6P3QVY0
LinkDB
Position
Unknown
AA seq 822 aa
MWSWKCLLFWAVLVTATLCTARPAPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDD
VQSINWLRDGVQLVESNRTRITGEEVEVRDSVPTDSGLYACVTSSPSGSDTTYFSVNVSD
ALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPS
SGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSIN
HTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKI
GPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLE
ALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIIYKMKSGTKKSDFHSQMAVHKLAKS
IPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVL
GKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGK
HKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDL
VSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNG
RLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMD
KPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSF
PDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR
NT seq 2469 nt   +upstreamnt  +downstreamnt
atgtggagctggaagtgcctcctcttctgggctgtgctggtcacagccacactctgcact
gccaggccagctccaaccttgcctgaacaagcccagccctggggagcccctgtggaagtg
gagtccttcctggtccaccctggtgacctgctgcagcttcgctgtcggctgcgggacgat
gtccagagcatcaactggctgcgggacggggtacagctggtggaaagcaaccgtacccgc
atcacaggggaggaggtggaggtgcgggattccgtgcctaccgactctggcctctacgct
tgtgtgaccagcagcccctcaggcagcgacaccacctacttctccgtcaatgtctcagat
gctctcccttcctcagaggatgatgatgacgatgatgactcctcttcagaggagaaagag
acagataacaccaaaccaaaccgtatgcccgtggctccatactggacgtccccagaaaag
atggaaaaaaaactgcatgcagtgccagctgccaagacagtgaagtttaaatgcccttcc
agtgggactcctaaccccacactgcgctggctgaaaaatggcaaggagtttaaacctgac
cacaggattggcggctacaaggtccgttatgccacctggagtatcataatggactccgtc
gtgccttctgacaagggcaattacacctgcattgtggagaatgagtatggcagcatcaac
catacctaccagcttgatgtcgtggagcggtcccctcaccggcccatcctgcaggcaggg
ttgcctgccaacaaaacagtggccctgggcagcaatgtggagttcatgtgtaaagtatac
agtgacccacagccccacatccagtggctaaagcacatcgaggtgaatgggagtaagatt
ggtccagacaacctgccttatgtccagatcttgaagactgccggagttaataccactgac
aaagagatggaagtgcttcacttaaggaatgtctcctttgaggacgcgggggagtatacg
tgcttggcgggtaactctatcggactctcccatcactctgcatggttgaccgttctggaa
gccctggaggagagaccggcggtgatgacctcacccctgtacctggagatcatcatctac
tgcacgggagccttcctcatctcctgcatggtggggtctgtcatcatctacaagatgaag
agtggcaccaagaagagtgacttccacagccagatggctgtgcacaagctggccaaaagc
atccctctgcgcagacaggtaacagtgtcagctgactccagcgcatccatgaactctggg
gttctgctggtccggccctcacgtctctcctccagtggcaccccaatgctggctggagtt
tctgaatatgagcttcccgaagacccccgctgggagctgcctcgagatagactggtttta
ggcaaacccctaggagagggctgctttgggcaggtggtgttggcggaggccattgggctg
gacaaggacaaacccaaccgtgtgaccaaagtggctgtgaagatgttgaagtcggatgca
acggagaaagacctgtcagacctgatctcagaaatggagatgatgaagatgattgggaaa
cacaagaacatcatcaacctgctgggggcctgcacacaggacggtcctttgtacgtcatc
gtggaatatgcctccaagggcaacctacgggagtacctgcaggcccggaggcctcctggg
ctggaatactgttacaatcccagccacaacccagaggagcagctctcctccaaggacctg
gtatcctgtgcctatcaggtggcccgaggcatggaatatctcgcctccaaaaagtgcata
caccgagacctggctgccaggaatgtcctggtgacggaggacaatgtgatgaagatcgca
gactttggcctagctcgagacattcaccacattgactactacaaaaagacaaccaatggc
cgactgcctgtgaagtggatggcacctgaggcattgtttgaccggatctacacccaccag
agtgatgtgtggtcttttggggtgcttctgtgggaaatcttcactctgggtggttcccca
tatcctggcgtgcctgtggaggagcttttcaagctgctgaaggagggtcatcgtatggac
aagcccagtaactgcaccaatgaactatacatgatgatgcgggattgttggcacgcagta
ccctctcaaagacctaccttcaagcagctggtagaagacctggaccgcattgtggccttg
acctccaaccaggagtatctggacctgtcaatgcccctggaccaatactctcccagcttt
cccgacacccgaagctctacctgctcctcaggggaggattctgtcttctctcatgagccg
ttgcctgaggagccctgtctgccccgacacccagcccagcttgccaatggtggactcaaa
cgacgctga

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