Pteropus vampyrus (large flying fox): 105301118
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Entry
105301118 CDS
T07815
Symbol
TBK1
Name
(RefSeq) serine/threonine-protein kinase TBK1 isoform X1
KO
K05410
TANK-binding kinase 1 [EC:
2.7.11.10
]
Organism
pvp
Pteropus vampyrus (large flying fox)
Pathway
pvp04014
Ras signaling pathway
pvp04137
Mitophagy - animal
pvp04140
Autophagy - animal
pvp04620
Toll-like receptor signaling pathway
pvp04621
NOD-like receptor signaling pathway
pvp04622
RIG-I-like receptor signaling pathway
pvp04623
Cytosolic DNA-sensing pathway
pvp04657
IL-17 signaling pathway
pvp04936
Alcoholic liver disease
pvp05014
Amyotrophic lateral sclerosis
pvp05022
Pathways of neurodegeneration - multiple diseases
pvp05135
Yersinia infection
pvp05160
Hepatitis C
pvp05161
Hepatitis B
pvp05162
Measles
pvp05163
Human cytomegalovirus infection
pvp05164
Influenza A
pvp05165
Human papillomavirus infection
pvp05167
Kaposi sarcoma-associated herpesvirus infection
pvp05168
Herpes simplex virus 1 infection
pvp05169
Epstein-Barr virus infection
pvp05170
Human immunodeficiency virus 1 infection
pvp05171
Coronavirus disease - COVID-19
pvp05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pvp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
105301118 (TBK1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
105301118 (TBK1)
04137 Mitophagy - animal
105301118 (TBK1)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
105301118 (TBK1)
04621 NOD-like receptor signaling pathway
105301118 (TBK1)
04622 RIG-I-like receptor signaling pathway
105301118 (TBK1)
04623 Cytosolic DNA-sensing pathway
105301118 (TBK1)
04657 IL-17 signaling pathway
105301118 (TBK1)
09160 Human Diseases
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
105301118 (TBK1)
05161 Hepatitis B
105301118 (TBK1)
05160 Hepatitis C
105301118 (TBK1)
05171 Coronavirus disease - COVID-19
105301118 (TBK1)
05164 Influenza A
105301118 (TBK1)
05162 Measles
105301118 (TBK1)
05168 Herpes simplex virus 1 infection
105301118 (TBK1)
05163 Human cytomegalovirus infection
105301118 (TBK1)
05167 Kaposi sarcoma-associated herpesvirus infection
105301118 (TBK1)
05169 Epstein-Barr virus infection
105301118 (TBK1)
05165 Human papillomavirus infection
105301118 (TBK1)
09171 Infectious disease: bacterial
05135 Yersinia infection
105301118 (TBK1)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
105301118 (TBK1)
05022 Pathways of neurodegeneration - multiple diseases
105301118 (TBK1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
105301118 (TBK1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
105301118 (TBK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pvp01001
]
105301118 (TBK1)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pvp04131
]
105301118 (TBK1)
Enzymes [BR:
pvp01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.10 IkappaB kinase
105301118 (TBK1)
Protein kinases [BR:
pvp01001
]
Serine/threonine kinases: Other
IKK family [OT]
105301118 (TBK1)
Membrane trafficking [BR:
pvp04131
]
Autophagy
Xenophagy
Other xenophagy associated proteins
105301118 (TBK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
TBK1_CCD1
Pkinase
TBK1_ULD
PK_Tyr_Ser-Thr
Pkinase_fungal
ABC1
Kinase-like
DUF713
CEP63
COG6_N
ubiquitin
Motif
Other DBs
NCBI-GeneID:
105301118
NCBI-ProteinID:
XP_011371952
UniProt:
A0A6P3R621
LinkDB
All DBs
Position
Unknown
AA seq
729 aa
AA seq
DB search
MQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLFAIKVFNNISFLRPVDVQMREFEVLK
KLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVV
GGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYL
HPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITG
KPSGAISGVQKAENGPIDWSGDMPVSCSLSRGLQVLLTPVLANILEADQEKCWGFDQFFA
ETSDILHRMIIHVFSLQQMTAHKIYIHSYNTATVFHELVYKQTKIISSNQELIYEGRRLV
LEPGRLAQHFPKTTEENPIFVVSQEPMSTIGLTYEKISLPKVHPRYDLDGDASMAKAITG
VVCYACRIASTLLLYQELMRKGIRWLIELVKDDYNETVHKKTEVVITLDFCIRNIEKTVK
VYEKLMKINLEAAELDEISDIHTKLLRLSSSQGTIETSLQDIESRLSPGGLLADTWAHQE
GTHPKDRHVEKLQVLLNYITEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMTH
FTDECVKKYEAFLNKSEEWVRKMLHLRKQLLSLANQCFDIEEEVSKYQDYTNELQETLPQ
KMIAASSGIKHAMTPIYPCSNTLVEMTLGMKKLKEEMEGVVKELAENNHILERFGSLTMD
GGLRNVDCL
NT seq
2190 nt
NT seq
+upstream
nt +downstream
nt
atgcagagcacttctaatcatctgtggcttttatctgatattttaggccaaggagctact
gcaaatgtctttcgtggaagacataagaaaactggtgacttatttgctatcaaagtattt
aataacataagcttccttcgtccagtagatgttcaaatgagagaatttgaagtgttaaaa
aaactcaatcacaaaaatattgtcaaattatttgcaattgaggaggagacaacaacaaga
cataaagtccttattatggaattttgtccatgtgggagtttatacactgttttagaagag
ccatctaatgcctatggactaccagagtctgaatttttaattgttttgcgagatgtggtg
ggtggaatgaatcatctccgagagaacggcatagtgcatcgtgatatcaagccaggaaat
atcatgcgtgttataggggaagatggacagtctgtttacaaactcacagattttggtgca
gctagagaattagaagatgatgagcagttcgtttctctgtatggcacagaagaatatttg
catcctgatatgtatgagagagcagtgctaagaaaagatcaccagaagaaatatggagca
acagttgatctttggagcattggggtaacgttttaccacgcagctactggatcactgcca
tttagaccatttgaagggccacgtaggaataaggaagtgatgtataaaataattactgga
aagccgtctggtgcaatatctggagtacagaaagcagaaaatggaccaatcgactggagt
ggagacatgcctgtttcttgtagtctttctcggggtcttcaagttctacttactcctgtt
cttgcaaacatccttgaggcagatcaggaaaagtgttggggttttgaccagttttttgca
gaaactagtgatatacttcaccgaatgataattcatgttttttcgctacaacaaatgaca
gctcataagatttatattcatagttataatactgctactgtatttcatgaactggtgtat
aaacaaaccaaaattatttcttcaaatcaagaacttatatatgaaggacgacgcttagtt
ctcgaacctggaagactggcacagcatttccctaaaactactgaggaaaaccctatcttt
gtagtaagccaggaacccatgagtaccataggactgacatatgaaaaaatttccctccct
aaagtacatccacgttatgatttagatggagatgctagcatggctaaggcaataacagga
gttgtgtgttatgcctgtagaattgccagtaccctgctgctttatcaggaattaatgcga
aaggggatacgatggttgatagaattagttaaagatgattataatgaaactgttcacaaa
aagacagaagttgtgatcacactggatttctgcatcagaaacattgaaaaaactgtgaaa
gtatatgaaaagttgatgaaaatcaacctagaagcagcagagttagatgaaatttcagac
atacacaccaaattgttgagactttccagttctcagggaacaatagaaaccagtcttcag
gatatcgaaagcagattatctccaggtggattgctggcggatacgtgggcccatcaagaa
ggcactcatccaaaagataggcatgtggaaaagctacaagtcctgttaaattacatcaca
gagatttactatcagttcaaaaaagacaaagcagaacgtagactggcttataatgaagaa
cagatccacaaatttgataagcaaaaactctattaccatgcaacaaaagccatgacccac
tttacagatgaatgtgttaaaaagtatgaggcatttttgaataagtcagaagaatgggtg
agaaagatgcttcatcttaggaaacagttattgtccctagctaatcaatgttttgatatt
gaagaagaagtatcaaagtatcaagactatactaatgagttacaagaaactttgcctcag
aaaatgattgcagcctccagtggaatcaaacatgccatgactccaatttatccatgttct
aacacattagtagaaatgactcttggtatgaagaaattaaaggaagaaatggaaggggtt
gttaaagaacttgctgaaaataatcatattttagaaaggtttggctctctaaccatggat
ggtggccttcgcaatgttgactgcctttag
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