Pteropus vampyrus (large flying fox): 105301705
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Entry
105301705 CDS
T07815
Symbol
SIRT1
Name
(RefSeq) NAD-dependent protein deacetylase sirtuin-1 isoform X1
KO
K11411
NAD-dependent protein deacetylase sirtuin 1 [EC:
2.3.1.286
]
Organism
pvp
Pteropus vampyrus (large flying fox)
Pathway
pvp00760
Nicotinate and nicotinamide metabolism
pvp01100
Metabolic pathways
pvp04068
FoxO signaling pathway
pvp04148
Efferocytosis
pvp04152
AMPK signaling pathway
pvp04211
Longevity regulating pathway
pvp04213
Longevity regulating pathway - multiple species
pvp04218
Cellular senescence
pvp04310
Wnt signaling pathway
pvp04922
Glucagon signaling pathway
pvp04936
Alcoholic liver disease
pvp05031
Amphetamine addiction
pvp05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
pvp00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
105301705 (SIRT1)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
105301705 (SIRT1)
04068 FoxO signaling pathway
105301705 (SIRT1)
04152 AMPK signaling pathway
105301705 (SIRT1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
105301705 (SIRT1)
09143 Cell growth and death
04218 Cellular senescence
105301705 (SIRT1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
105301705 (SIRT1)
09149 Aging
04211 Longevity regulating pathway
105301705 (SIRT1)
04213 Longevity regulating pathway - multiple species
105301705 (SIRT1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
105301705 (SIRT1)
09165 Substance dependence
05031 Amphetamine addiction
105301705 (SIRT1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
105301705 (SIRT1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
pvp03036
]
105301705 (SIRT1)
03029 Mitochondrial biogenesis [BR:
pvp03029
]
105301705 (SIRT1)
Enzymes [BR:
pvp01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.286 protein acetyllysine N-acetyltransferase
105301705 (SIRT1)
Chromosome and associated proteins [BR:
pvp03036
]
Eukaryotic type
Histone modification proteins
HDACs (histone deacetylases)
SIRTs (sirtuins, class III HDACs)
105301705 (SIRT1)
Mitochondrial biogenesis [BR:
pvp03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
105301705 (SIRT1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
SIR2
DUF592
Motif
Other DBs
NCBI-GeneID:
105301705
NCBI-ProteinID:
XP_011372784
UniProt:
A0A6P3R1D9
LinkDB
All DBs
Position
Unknown
AA seq
740 aa
AA seq
DB search
MADEAALALQPGGSPSAVSAEKESESPPTGEPLRKRPRRDGPGLGRSPGELDGTAPEREA
PAAAGGGPAAAAAAALWREVAAAGGEREAQVAAGGEGDNGPGLQVLSREPPPADDLDDDD
DEGEEEEEAAAIGYRDNLLFGDEIITNGFHSCESDEDDRASHASSSDWTPRPRIGPYTFV
QQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVK
LLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRP
FFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFAT
ASCLICKYKVDCETVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKY
DKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINE
LCHRLGGEYAKLCCNPVKLSEITEKPPRTQKELAHLSELPPTPLNISEGSSSPERTSPPD
SSVIVTFVDQATKSNIDDADVSESKDCMEEKSQEIQTSTRSVESVTEQLESPDLKNVGSN
TGEKNERTSVVETVRKCWPARLAKEQISKRLDGNQYLFLPPNRYIFHGAEVYSDSEDDVL
SSSSCGSNSDSGTCQSPSLEEPMEDESEIEEFYNGLEDDADIERVGGTGFGADGGDHEAV
NEAISLKQEATDISYPSNKP
NT seq
2223 nt
NT seq
+upstream
nt +downstream
nt
atggcggacgaggcggcgctcgccctgcagcccggcggctccccgtcggcggtgtcggcc
gagaaggagtctgagtcgccgcccacaggagagccgctccgcaagaggccgcggagagat
ggccccggcctcgggcggagcccgggcgagctcgatgggacggcccccgagcgtgaggcg
ccggcagcggccgggggcggcccggcggcggcggcggcggcggcgctgtggcgggaggtg
gccgcggcgggcggggagcgggaggcccaggtggcggcgggcggagaaggagacaatggg
ccgggcctacaggtcctatcccgagagccgccgccggccgacgacctcgacgacgacgac
gacgagggcgaggaggaggaagaggcggcagcgattgggtaccgagataaccttctgttt
ggtgatgaaataatcaccaatggttttcattcttgtgaaagtgatgaggatgatagagct
tcacatgcaagctctagtgactggactccaaggccacggataggtccatatacttttgtt
cagcaacatcttatgattggtaccgatcctcgaacaattcttaaagatttactaccagaa
acaattcctccacctgaattggatgatatgacactgtggcagattgttattaatatcctt
tcagaaccaccaaaaaggaaaaagagaaaagatattaatacaattgaagatgctgtgaaa
ttactgcaggagtgcaaaaaaataatagttctaactggagctggggtttctgtttcttgt
ggaatacctgacttcaggtcaagagatggtatttatgctcgccttgcagtagacttccca
gaccttcctgatcctcaagcaatgtttgatattgaatatttcagaaaagatccaagacca
ttcttcaagtttgcaaaggaaatatatcctggacagttccaaccatctctctgtcacaaa
ttcatagccttgtcagataaggaaggaaagctacttcggaactatactcagaacatagat
acactggaacaagttgcaggaatccaaaggataattcagtgtcatggttcctttgcaaca
gcgtcttgcctgatttgtaaatacaaagttgactgtgaaactgtacgaggagatattttt
aatcaggtggttcctcgatgtcctaggtgtccagctgatgaaccacttgctattatgaaa
ccagagattgtcttttttggtgaaaatttaccagaacagtttcatagagccatgaagtat
gacaaagatgaagttgatctccttattgttattggatcttccctgaaagtaagaccagta
gcactaattccaagttccataccccatgaagtgcctcagatattaattaatagggaacct
ttgcctcatctgcattttgatgtagagcttcttggagactgtgatgtcataattaatgaa
ttgtgtcatagactaggtggtgaatatgcaaaactttgctgcaaccctgtaaagctttca
gaaattactgaaaaacctccacgaacacaaaaagagttggctcatttgtcagagttgcca
cccacaccccttaatatttcagaaggctcaagttcaccagaaagaacttcaccaccagat
tcttcagtgattgtcacatttgtagaccaagcaacaaagagtaatattgatgatgcagat
gtgtctgaatcaaaagattgtatggaagaaaaatcacaggaaatacagacttctactagg
agcgttgaaagtgttactgaacagttggagagtccggatttgaagaacgttggctccaat
actggcgagaaaaatgaaagaacttcagttgttgaaacagtgagaaagtgctggccagct
agactcgcaaaggagcagatcagtaaacggcttgatggtaatcagtatctgtttttacca
ccaaatcgttacattttccatggcgctgaggtatattcagactctgaagatgacgtctta
tcctctagttcttgtggcagtaatagtgatagcggaacatgccagagtccaagtttagaa
gaacccatggaggatgaaagtgagattgaagaattttacaatggtttggaagacgatgct
gatattgagagagttggaggaactggatttggagctgatggaggtgatcacgaggcagtt
aatgaagctatatccctgaaacaggaagcaacagacattagctatccatcaaacaaacca
taa
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