Pteropus vampyrus (large flying fox): 105304805
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Entry
105304805 CDS
T07815
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
pvp
Pteropus vampyrus (large flying fox)
Pathway
pvp00270
Cysteine and methionine metabolism
pvp00480
Glutathione metabolism
pvp01100
Metabolic pathways
pvp01240
Biosynthesis of cofactors
pvp04216
Ferroptosis
Module
pvp_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
pvp00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
105304805 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
105304805 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
105304805 (GCLC)
Enzymes [BR:
pvp01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
105304805 (GCLC)
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Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
105304805
NCBI-ProteinID:
XP_011377392
UniProt:
A0A6P3R8Y2
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Position
Unknown
AA seq
637 aa
AA seq
DB search
MGLLSQGSPLSWEETKRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
ENKKVQLVLSGEEVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMRKRRKEATSLLEENQALCTITSFPRLGCPGFTLPEFKPNPVEEGASKSLFFPDEAI
NKHPRFGTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPEDDEAAKASKPDHIYMDA
MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI
SASVDDRTREERGLEPLKNNNYRISKSRYDSIDSYLSECGEKYNDIELTIDKAIYEQLLQ
EGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVL
QGMFYFRKDICKGGSAVVDGCGKSQNSAELAAEEYTLMSIDTIVNGKEGVFPGLIPVLNS
YLENMEVDVDTRCSILNYLKLIKKRASGELMTVAKWMREFIANHPDYKQDSVITDEMNYS
LILKCNQIADELCECPELHGPAFRKVKYSGSKTDSSN
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcccaaggatcgccgctgagctgggaggagaccaagcgccacgccgac
cacgtgcggcggcacgggatcctccagttcctgcacatctaccacgccgtcaaggaccgg
cacaaggatgtgctcaagtggggcgacgaggtggaatacatgttggtgtcttttgatcat
gaaaataaaaaagtccaattggtcctatctggagaagaagttcttgaaactctacaagaa
aaaggggaaaggacaaacccaaaccatcctaccctttggagaccagagtatgggagttac
atgattgaagggacaccgggacagccctacggaggaacaatgtctgagttcaacacagtt
gaagacaacatgagaaaacgccggaaggaggcaacttctttattagaagaaaatcaggct
ctttgcacaataacttcatttcccagattaggctgtcctgggttcacgctgcctgagttc
aaacccaacccagttgaagaaggtgcttccaagtccctcttctttcccgatgaagcaata
aacaagcatccccgctttggcaccctaacaagaaatatccgacataggagaggagaaaag
gttgtcatcaatgtaccaatttttaaggacaagaatacaccatctccatttatagaaaca
tttcctgaggatgatgaggcagcaaaggcttctaagcctgatcatatttacatggatgcc
atgggatttggaatgggcaattgctgtcttcaggtaacattccaagcttgcagcatatct
gaggctagatacctttatgatcagttggctactatctgcccaattgtgatggctttgagt
gctgcgtctcctttttaccgaggctatgtgtcagacattgattgtcgctggggagtgatt
tctgcatctgtagatgatagaactcgggaggaaagaggactggagccactgaagaacaat
aactacagaattagtaaatcccgatatgattcaatagacagttatttatctgagtgtggt
gagaaatataatgacatcgagttgacaatagataaagcaatctacgaacaactgttgcag
gaaggcattgatcatctcctggcccagcatgttgctcacctctttattagagacccactg
actctgtttgaagagaaaatacacctggacgatgccaatgagtctgaccattttgagaat
attcagtccacaaactggcaaacaatgagatttaagcctcctcctccaaactcagatatc
ggatggagagtagaattccgacccatggaggttcagttaacggactttgagaactctgca
tatgtggtatttgtcgtgctgctcactagagtgatcctttcatacaaactggattttctc
attccgctgtcaaaggttgatgaaaacatgaaagtagcacagaaacgagatgctgttctg
cagggaatgttctatttcaggaaagacatttgcaaaggtggcagcgccgtggtggacggc
tgtggcaagtcccagaacagcgcggagctggcggcggaggagtacaccctgatgagcatc
gacaccatcgttaacgggaaggaaggtgtgtttcccgggctgatcccagttctgaactcc
taccttgaaaacatggaagtggatgtggataccagatgtagcattctgaactacttaaag
ctgattaagaagagagcatcgggagaactaatgacagttgcaaaatggatgagagagttt
attgcaaaccatcctgactacaagcaagacagtgtgataactgatgaaatgaactatagc
cttattttaaagtgtaaccaaattgcagatgaattatgtgaatgcccagagttacatgga
ccagcatttaggaaagtaaaatatagtggaagtaaaaccgactcctccaactag
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