Pteropus vampyrus (large flying fox): 105304993
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Entry
105304993 CDS
T07815
Symbol
ACACA
Name
(RefSeq) acetyl-CoA carboxylase 1 isoform X3
KO
K11262
acetyl-CoA carboxylase / biotin carboxylase 1 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
pvp
Pteropus vampyrus (large flying fox)
Pathway
pvp00061
Fatty acid biosynthesis
pvp00620
Pyruvate metabolism
pvp00640
Propanoate metabolism
pvp01100
Metabolic pathways
pvp01212
Fatty acid metabolism
pvp04152
AMPK signaling pathway
pvp04910
Insulin signaling pathway
pvp04922
Glucagon signaling pathway
pvp04936
Alcoholic liver disease
Module
pvp_M00082
Fatty acid biosynthesis, initiation
Brite
KEGG Orthology (KO) [BR:
pvp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
105304993 (ACACA)
00640 Propanoate metabolism
105304993 (ACACA)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
105304993 (ACACA)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
105304993 (ACACA)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
105304993 (ACACA)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
105304993 (ACACA)
04922 Glucagon signaling pathway
105304993 (ACACA)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
105304993 (ACACA)
Enzymes [BR:
pvp01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
105304993 (ACACA)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
105304993 (ACACA)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
105304993 (ACACA)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
Motif
Other DBs
NCBI-GeneID:
105304993
NCBI-ProteinID:
XP_011377698
UniProt:
A0A6P3R9L2
LinkDB
All DBs
Position
Unknown
AA seq
2346 aa
AA seq
DB search
MDEPSPLAKTLELNQHSRFIIGSVSEDNSEDEISNLVKLDLLEEKEGSLSPASVSSDALS
DLGISSLQDGLALHVRPSMSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEK
VLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPG
GPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWAL
GDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYEKGYVKDVDDGLKA
AEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEV
QILADQYGNAISLFGRDCSVQRRHQKIIEEAPAAIATPAVFEHMEQCAVKLAKMVGYVSA
GTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMY
GVSPWGDAPIDFENSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGY
FSVAAAGGLHEFADSQFGHCFSFGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLET
ESFQLNRIDTGWLDRLIAEKVQAERPDTMLGVVCGALHVADVSLRNSISNFLHSLERGQV
LPAHTLLNTVDVELIYEGAKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDG
SSYTTYMKEEVDRYRITIGNKTCVFEKENDPSVMRSPSAGKLIQYIVEDGGHVFSGQCYA
EIEVMKMVMTLTAAESGCIHYVKRPGAALDPGCVIAKMQLDNPSKVQQAELHTGSLPQIQ
STALRGEKLHRVFHYVLDNLVNVMNGYCLPDPFFSSRVKDWVERLMKTLRDPSLPLLELQ
DIMTSVSGRIPPNVEKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREV
FFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQNGHYDKCVFVLREENKSD
MNTVLNYIFSHAQVTKKNLLVTMLIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALR
ARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYH
SNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLNRM
SFSSNLNHYGMTHVASVSDVLLDNSFTPPCQRMGGMVSFRTFEDFVRIFDEVIGCFCDSP
PQSPTFPEAGHTSLYDEDKVPRDEPIHILNVAIKTDCDIEDDRLAVMFREFTQQNKATLV
EHGIRRLTFLVAQKDFRKQISYEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQ
LELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFE
YLQNEGERLLLEAMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYG
SRLWKLRVLQAELKINIRLTPTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQA
YGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWDSMSTQT
FLPSPPLPSDMLTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMTLKSPEYPEGRDIIVI
GNDITYKIGSFGPQEDWLFLRASELARAEGIPRIFVAANSGARIGLAEEIRHMFHVAWVD
PEDPYKGYKYLYLTPQDYKRVSALNSVYCEHVEDEGESRYKITDIIGKEDGIGVENLRGS
GMIAGESSLAYDEIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGR
EVYTSNNQLGGIQIMHNNGVTHSTVCDDFEGVFTILHWLSYMPKNVNSSVPILNSKDPID
RIIEFVPTKAPYDPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGG
IPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTSQAIKDFNREGLPL
MVFANWRGFSGGMKDMYDQVLKFGAFIVDGLRECSQPVMVYIPPQAELRGGSWVVIDPTI
NPRHMEMYADRESRASVLEPEGTVEIKFRRKDLVKTMRRVDPVYIHLAERLGTPELSAAE
RKELENKLKEREEFLIPIYHQIAVQFADLHDTPGRMQEKGIINDILDWKTSRTFFYWRLR
RLLLEELVKKKIHTANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQLTE
EDSARSVIEENIKYIRRDYVLKQIRSLVQANPEVAMDSIVYMTQHISPTQQAEVVRILST
MESPST
NT seq
7041 nt
NT seq
+upstream
nt +downstream
nt
atggatgaaccatcccccttggccaaaactctagagctgaaccagcactccagattcatt
attggttctgtgtctgaagataactcagaagatgagatcagcaacctggtgaagctagac
ctactggaggaaaaggagggctctctgtcaccagcttctgtcagctcagatgcactctct
gatttagggatctctagcctacaggatggcttggccttacatgtgaggcccagcatgtct
ggcttgcacctagtaaagcaaggtcgagaccgaaagaaaatagactcacagcgagatttc
actgtagcttctccagcagaattcgttactcgttttggggggaataaagtgattgagaag
gttcttattgccaacaatggcattgcagcagtgaaatgcatgcgatctatccgtcggtgg
tcttatgagatgtttagaaatgagcgtgcaatccgatttgttgtcatggtcacacctgaa
gaccttaaagccaatgcagagtacattaaaatggcagatcactacgtgccagtaccagga
ggaccaaacaacaacaactatgcaaatgtggaattaattcttgatattgctaaaaggatc
ccagtccaagcagtgtgggctggctggggtcatgcttctgaaaatcccaagctcccagaa
cttcttttgaaaaatggtatcgccttcatgggcccaccaagccaggccatgtgggctttg
ggggataagattgcgtcttccatagtggctcaaactgcgggtatcccaactcttccctgg
agtggcagtggtcttcgtgtggactggcaggaaaatgacttttcaaaacgtatcttaaat
gttccccaggaactatatgaaaaaggttatgtgaaggatgtggatgatgggctaaaggca
gcagaggaagttggatatccagtaatgatcaaggcctcagaaggaggaggagggaaggga
atcagaaaagtcaacaatgcagatgacttccctaacctcttcagacaggttcaagctgaa
gtccctggatcacctatatttgtgatgagactagctaagcaatctcgtcatctggaggtg
cagatcttagcagatcagtatggcaatgctatctctttgtttggtcgtgattgctctgtg
cagcgcaggcatcagaagattattgaagaggcacctgctgctattgctactccagcagta
tttgaacatatggaacagtgtgcggtgaaacttgccaaaatggttggttatgtgagtgcg
ggaactgtagaatacctctacagccaggatggcagtttctactttctggaactgaaccct
cggctacaggtggagcacccttgtaccgagatggtggctgatgtcaatctccctgcagca
caactccagattgccatggggatccctctgtacagaatcaaggatattcgtatgatgtat
ggggtatctccctggggtgatgctcccattgattttgaaaattctgctcatgttccttgc
ccaaggggccatgttattgctgctcggatcactagtgaaaatccagatgagggtttcaag
cccagttcaggaacagttcaggaactgaatttccgtagcaataagaacgtttggggttat
ttcagtgttgctgctgcagggggacttcatgaatttgctgattctcagttcggtcactgc
ttttcctttggagaaaacagagaggaagcaatttcaaacatggtggtggctttgaaggag
ctatctattcggggtgactttcgaactacagttgaatacctgatcaaattgttggagact
gaaagctttcagttgaatagaattgacactggctggctggacagactgatagcagaaaaa
gtacaggcagagcgacctgataccatgttgggagttgtctgtggggctctccatgtggct
gatgtgagcctgcgaaatagcatctctaacttccttcactccttagaaaggggtcaagtc
cttcctgctcatacacttctaaatacagtagatgtggaacttatctatgaaggagccaag
tatgtacttaaggtgactcgacagtcccctaactcttatgtggtgatcatgaatggctca
tgtgtagaagtagatgtgcatcggctgagtgatggggggctcctcttgtcctatgacggc
agcagttataccacgtacatgaaggaggaagtggatagatatcgtatcacaattggcaat
aaaacctgtgtgtttgagaaagagaatgacccttcagtgatgcgctcaccttctgctggg
aagttaatacagtacattgtggaggatggaggtcatgtgttttctggccagtgctatgct
gagattgaggtgatgaagatggtaatgaccttaacagctgcagagtctggctgtattcat
tatgtcaagcgtcctggagcagctcttgacccaggctgtgtaatagctaaaatgcagttg
gacaatcccagcaaggtccagcaggctgagcttcacacaggcagtctgccacagatccag
agcacagcactcagaggtgaaaagctccatcgagtgttccactatgtcctggataatctg
gtcaacgtaatgaatggatactgccttccagatcctttctttagcagcagggtaaaagac
tgggtagagcggttgatgaagacactcagagatccctccctacctctcctagaattgcaa
gatattatgaccagtgtctctggccgcatccctcccaatgtggaaaagtctatcaagaag
gaaatggctcagtatgccagcaatatcacatcagtcctctgtcagtttcccagccagcag
attgccaacatcctagatagccatgcagctaccttgaaccggaaatctgaacgagaagtc
ttcttcatgaacactcagagcattgtccaactggtacagaggtaccgaagtggcatccga
ggccacatgaaggctgtagtgatggatctgctgcgacagtacctgcgagtagagacacag
tttcagaatggtcactatgacaaatgtgtgttcgtccttcgagaggagaacaagagtgac
atgaacactgtactgaactatatcttctctcatgctcaagttaccaagaagaatcttctg
gtcacaatgcttattgatcagttgtgtggccgggaccccactctcactgatgagctgctg
aatatcctcacagagctaactcaacttagtaagaccaccaatgctaaagtggcacttcga
gcgcgccaggttcttattgcctcccatttaccatcatacgagcttcgtcataaccaagta
gagtctatcttcctatcagctattgacatgtatggacatcagttttgcattgaaaaccta
cagaaactcatcttgtctgaaacatctattttcgatgtcctgccaaacttcttctatcac
agcaaccaggtggtgaggatggcggctctggaggtgtatgttcgaagggcttatattgcc
tatgaacttaacagtgtacaacaccgccagcttaaggacaacacttgtgtggtggaattc
cagttcatgctgcccacatctcatccaaacagagggaacatccccacgctaaacagaatg
tccttctcctccaacctcaaccactatggcatgactcatgtagctagtgtcagcgatgtt
ctattggacaactcatttactccaccatgtcagcggatgggtggaatggtctcttttcgg
acttttgaagattttgtcaggatctttgatgaagtgataggctgcttctgtgattcccca
ccccaaagccctacatttcctgaggcaggtcacacgtctctatatgatgaagacaaggtc
cccagggatgaaccaattcacattctgaatgtggctatcaagaccgactgtgatattgag
gatgacaggctggcagtgatgttcagagagtttacccagcaaaataaagctaccctggtt
gagcatggaatccggcgccttactttcctggttgcacaaaaggatttcagaaaacagatc
agctatgaggtggatcagagatttcatagagaattccctaaatttttcacattccgagca
agggataagtttgaagaggatcgtatctaccgtcacctggagcctgcccttgctttccag
ttagagctgaaccggatgagaaattttgaccttactgccattccatgtgctaatcacaag
atgcacctgtatcttggggcagccaaggtggaagttggcacagaagtgacagactacagg
ttctttgtccgtgcaatcatcagacattctgatctggtcaccaaggaagcttcttttgaa
tatctacaaaacgaaggggagcgactgctcctagaagccatggatgagttggaagtcgct
tttaacaatacaaatgtccgtactgactgcaaccacatcttcctcaactttgtgcctaca
gtcatcatggacccatcaaagattgaggaatctgtgcggagcatggtaatgcgctatgga
agtcggctgtggaaattacgcgtcctccaggcagaactgaaaatcaacattcgcctgaca
ccaactggaaaagcaattcccatccgcctcttcctgacaaacgagtctggctattacttg
gacatcagcctgtacaaggaagtgactgactccaggacagcacagatcatgtttcaggcg
tatggagacaaacagggtccactgcatggaatgttaatcaacactccatatgtgaccaaa
gacttgcttcaatcaaagaggttccaggcacaatccttagggacaacatacatttatgat
atcccagagatgtttcgacagtccctgatcaaactctgggattctatgtccactcaaaca
ttccttccatcaccccctctgccttcggacatgctgacgtatacggagcttgtgttggat
gatcaaggtcaactggtccacatgaacaggcttccaggaggaaatgagatcggcatggta
gcttggaaaatgacccttaagagtcctgaatatccagaaggccgagatatcattgttatt
ggcaatgacatcacgtacaaaattgggtcctttgggccccaggaggactggctgtttctc
agagcctctgagcttgccagggcagagggtattccacgcatctttgtagcagccaacagt
ggagcaagaattggactggcagaggaaattcgtcatatgtttcacgtggcctgggtagat
cctgaggatccttacaagggatacaaatatttatatctgacccctcaagattataagaga
gtcagtgctctcaactctgtctattgtgaacatgtagaggatgaaggagaatctaggtac
aagataactgatattatcgggaaagaagacggaattggagtagagaatcttcgaggttct
ggaatgattgctggagaatcttcattggcctatgatgagatcatcaccattagcctggtt
acgtgccgagccattggaataggcgcttaccttgttcggctgggacagagaaccatccag
gttgaaaattctcacttaattctgacaggagctggggccctcaacaaagtccttggaagg
gaagtgtacacctctaacaaccagctcgggggcatccagatcatgcacaacaatggggtg
actcacagcaccgtttgtgatgactttgaaggggttttcactatcctgcactggctgtct
tacatgcccaagaatgtaaacagttcagttcctatcctgaactccaaggatcctatagat
agaatcatcgagtttgttcccacaaaggccccatatgatccccgatggatgctagcaggc
cgtcctcacccaacccagaaaggtcagtggttgagtggattttttgactatgggtctttc
tcagaaatcatgcaaccctgggcacagactgtggtggttggcagagccaggctgggagga
atacctgtgggagtagttgctgtagaaacccgaacagtggaactaagtatcccagctgat
cccgcaaacctggattctgaagccaagatcatccagcaggctggccaggtttggttccca
gactctgcatttaagacctctcaggctatcaaggacttcaaccgtgaagggctgcctctg
atggtctttgctaactggagaggtttctctggtgggatgaaagatatgtacgaccaggtg
ctgaagtttggtgcttttatcgtggatggcttacgggaatgctctcagcctgtgatggtt
tacattcctccccaggccgagcttcggggaggctcctgggtcgtgattgatcccaccatc
aacccccggcacatggagatgtatgctgaccgagaaagcagggcatcagttctggagcca
gaagggacagtagaaatcaaattccgcagaaaagatctggtgaaaaccatgcgtcgggtg
gacccagtctacatccacttggctgagcgattgggcaccccagagttaagcgcagctgag
cggaaggagctggagaacaagttgaaggagcgggaggaattcctaattcccatttaccat
cagatagccgtgcagtttgctgacttgcacgacacaccgggccggatgcaggagaagggt
attattaacgacatcctggactggaaaacatcccgtaccttcttctactggcggctgcgg
cgtctcctgctggaggagctggtcaagaagaaaatccacactgccaaccctgagctgact
gatggccagatccaggccatgttaaggcgctggttcgtggaggtagaaggaacggtgaag
gcctacgtttgggacaacaacaaggatctggtggaatggctggagaaacagctgacagag
gaagacagcgctcgctcggtgatagaggaaaacatcaaatacattaggagagactacgtc
ctcaagcagatccgcagtttggtacaggccaatccggaggttgccatggattccatcgtc
tacatgacccagcacatctcacccactcagcaagcagaagtcgtgcggatcctctccaca
atggagtctccttcaacatag
DBGET
integrated database retrieval system
