KEGG   Pteropus vampyrus (large flying fox): 105306141
Entry
105306141         CDS       T07815                                 
Name
(RefSeq) epidermal growth factor receptor-like
  KO
K04361  epidermal growth factor receptor [EC:2.7.10.1]
Organism
pvp  Pteropus vampyrus (large flying fox)
Pathway
pvp01521  EGFR tyrosine kinase inhibitor resistance
pvp01522  Endocrine resistance
pvp03272  Virion - Hepatitis viruses
pvp04010  MAPK signaling pathway
pvp04012  ErbB signaling pathway
pvp04014  Ras signaling pathway
pvp04015  Rap1 signaling pathway
pvp04020  Calcium signaling pathway
pvp04066  HIF-1 signaling pathway
pvp04068  FoxO signaling pathway
pvp04072  Phospholipase D signaling pathway
pvp04144  Endocytosis
pvp04151  PI3K-Akt signaling pathway
pvp04510  Focal adhesion
pvp04520  Adherens junction
pvp04540  Gap junction
pvp04630  JAK-STAT signaling pathway
pvp04810  Regulation of actin cytoskeleton
pvp04912  GnRH signaling pathway
pvp04915  Estrogen signaling pathway
pvp04921  Oxytocin signaling pathway
pvp04926  Relaxin signaling pathway
pvp04928  Parathyroid hormone synthesis, secretion and action
pvp04934  Cushing syndrome
pvp05160  Hepatitis C
pvp05163  Human cytomegalovirus infection
pvp05165  Human papillomavirus infection
pvp05171  Coronavirus disease - COVID-19
pvp05200  Pathways in cancer
pvp05205  Proteoglycans in cancer
pvp05206  MicroRNAs in cancer
pvp05207  Chemical carcinogenesis - receptor activation
pvp05208  Chemical carcinogenesis - reactive oxygen species
pvp05210  Colorectal cancer
pvp05212  Pancreatic cancer
pvp05213  Endometrial cancer
pvp05214  Glioma
pvp05215  Prostate cancer
pvp05218  Melanoma
pvp05219  Bladder cancer
pvp05223  Non-small cell lung cancer
pvp05224  Breast cancer
pvp05225  Hepatocellular carcinoma
pvp05226  Gastric cancer
pvp05230  Central carbon metabolism in cancer
pvp05231  Choline metabolism in cancer
pvp05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:pvp00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03272 Virion - Hepatitis viruses
    105306141
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105306141
   04012 ErbB signaling pathway
    105306141
   04014 Ras signaling pathway
    105306141
   04015 Rap1 signaling pathway
    105306141
   04630 JAK-STAT signaling pathway
    105306141
   04066 HIF-1 signaling pathway
    105306141
   04068 FoxO signaling pathway
    105306141
   04020 Calcium signaling pathway
    105306141
   04072 Phospholipase D signaling pathway
    105306141
   04151 PI3K-Akt signaling pathway
    105306141
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    105306141
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    105306141
   04520 Adherens junction
    105306141
   04540 Gap junction
    105306141
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    105306141
 09150 Organismal Systems
  09152 Endocrine system
   04912 GnRH signaling pathway
    105306141
   04915 Estrogen signaling pathway
    105306141
   04921 Oxytocin signaling pathway
    105306141
   04926 Relaxin signaling pathway
    105306141
   04928 Parathyroid hormone synthesis, secretion and action
    105306141
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105306141
   05206 MicroRNAs in cancer
    105306141
   05205 Proteoglycans in cancer
    105306141
   05207 Chemical carcinogenesis - receptor activation
    105306141
   05208 Chemical carcinogenesis - reactive oxygen species
    105306141
   05230 Central carbon metabolism in cancer
    105306141
   05231 Choline metabolism in cancer
    105306141
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    105306141
  09162 Cancer: specific types
   05210 Colorectal cancer
    105306141
   05212 Pancreatic cancer
    105306141
   05225 Hepatocellular carcinoma
    105306141
   05226 Gastric cancer
    105306141
   05214 Glioma
    105306141
   05218 Melanoma
    105306141
   05219 Bladder cancer
    105306141
   05215 Prostate cancer
    105306141
   05213 Endometrial cancer
    105306141
   05224 Breast cancer
    105306141
   05223 Non-small cell lung cancer
    105306141
  09172 Infectious disease: viral
   05160 Hepatitis C
    105306141
   05171 Coronavirus disease - COVID-19
    105306141
   05163 Human cytomegalovirus infection
    105306141
   05165 Human papillomavirus infection
    105306141
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    105306141
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    105306141
   01522 Endocrine resistance
    105306141
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pvp01001]
    105306141
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:pvp04147]
    105306141
Enzymes [BR:pvp01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     105306141
Protein kinases [BR:pvp01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   105306141
Exosome [BR:pvp04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   105306141
  Exosomal proteins of pancreatic cancer cells
   105306141
  Exosomal proteins of bladder cancer cells
   105306141
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 DUF6691 ABC1 GAPT Haspin_kinase
Other DBs
NCBI-GeneID: 105306141
NCBI-ProteinID: XP_023379631
UniProt: A0A6P6BWX7
LinkDB
Position
Unknown
AA seq 950 aa
MLNNCEVVLGNLEITYMQRNYDLSFLKTIQEVAGYVLIALNVAETIPLENLQIIRGNVLF
ENTHALSVLSNYGANKTGLRELPMRNLQEILQGAVRFNNNPLLCNVETIQWRDIVDSTFL
SNMSLDFQNQMSSCPKCDPGCPNGSCWGAGQENCQKHFPGNGSPVCLTCAGTTHAEAQVC
HKFRDEATCKDTCPPLMLYNPTTYEMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRAC
SSDSYEVEEDGVRKCKKCEGPCRKVCNGIGIGEFKDTLSINATNIKHFKNCTSISGDLHI
LPVAFKGDSFTHTPPLDPKELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTK
QHGQFSLAVVGLHITSLGLRSLKEISDGDVVISGNQKLCYADTIRWQNLFGTFSQKTKII
NNRNGQDCQAAGHVCNPLCSSEGCWGPEPKDCVSCRNVSRDRECVERCNLLEGEPREFVE
NSECVQCHPECLPQAMNVTCTGRGPDKCVKCAHYIDGPHCVKTCPSGIMGENNTLVWKFS
DANHVCHLCHRNCTYGCTGPGLEGCTHGPGIPSIATGIVGGLLLVVVLALGVVLFLRRRY
IVRKRTLRRLLQERELVEPLTPSGEAPNQALLRVLKETEFKKIKVLGSGAFGTVYKGLWN
PEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLVTQL
MPFGCLLDYVREHKDNIGSQCLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVK
ITDFGLAKLLGAEEKEYHAEGGKRLWEQALLGEWVVLTPPGAKGSKRVTVWELMTFGSKP
YDGIPASEVSALLEKGERLPQPPICTIDVYMIMVKCEWPGPSARAWPHLALRGPCRARKG
IAAWSQTIETLEFPKEVLSYSSQQALGSKSMCQCSPRHSSGDTCLTHRAS
NT seq 2853 nt   +upstreamnt  +downstreamnt
atgctgaacaactgtgaggtggtccttgggaacctggaaattacctatatgcaaagaaat
tacgacctttccttcttaaagaccatccaggaggtggccggctacgtcctcatcgccctc
aacgtggcggagacgatcccgctggaaaacctgcagatcatcagagggaacgtgctcttc
gaaaacacgcacgccttgtcggtcctgtccaactacggggcaaacaaaacggggctgcgg
gagctccccatgagaaacctgcaggaaatcctgcaaggcgccgtgcgattcaacaacaac
cccctcctctgcaacgtggagaccatccagtggcgagacatcgtggacagcactttcctg
agcaacatgtcgctggactttcagaaccagatgagcagctgcccaaagtgcgacccaggc
tgtcccaacgggagctgctggggtgcgggacaggagaattgccagaaacattttcctggg
aacggaagccccgtctgccttacctgcgccggcaccacccacgcagaagcacaagtctgt
cacaagttccgggacgaagccacgtgcaaggacacctgcccgccgctcatgctgtacaac
cccaccacgtacgagatggacgtcaacccggagggcaaatacagcttcggcgccacctgc
gtgaagaagtgcccccgtaactatgtggtgacagaccacggctcgtgcgtccgtgcctgc
agctctgacagctacgaggtggaggaggacggggttcgcaagtgtaagaagtgcgaaggg
ccttgtcgcaaagtttgtaacggaataggaattggtgaatttaaagacacactttccata
aatgctacgaatatcaaacacttcaaaaactgcacctccatcagtggggaccttcacatc
ctgccggtagctttcaagggtgactctttcactcacaccccgcctctggacccgaaggaa
ctggacattctgaaaaccgtgaaggagataacagggtttttgctgattcaggcctggcca
gaaaacaggactgacctccatgctttcgagaacctggaaatcatacgcggcagaacaaag
caacatggccagttttctctcgcggttgtcggcctgcacattacgtcgctggggctacgc
tccctcaaggagataagtgacggagacgtggtcatctcggggaaccagaagttgtgctac
gcagacaccatacgctggcaaaacctatttgggaccttcagccagaaaaccaagattata
aacaataggaatggacaggactgccaggccgcgggccacgtctgtaacccactctgctcg
tcagagggctgctggggcccggagccaaaggactgtgtgtcctgcaggaacgtcagccgt
gaccgggagtgcgtggagaggtgcaacctcctggagggcgagcccagggagtttgtggag
aactctgagtgcgtgcaatgccatccagaatgcctgccccaggccatgaacgtaacctgc
acgggacgcggaccagacaagtgtgtaaagtgtgcccactacatcgatggcccccactgt
gtcaagacctgcccgtctgggatcatgggagaaaacaacacgctggtctggaagttctcg
gatgccaatcacgtgtgtcacctgtgccaccgaaactgtacatacggctgcactgggccg
ggtctcgaaggctgcacgcatgggcccgggatcccgtccatcgccaccggcatcgtgggc
ggcctgctgctggtggtggtgctggccctcggggtcgtcctcttcctgcgcaggcgttac
atcgtccggaagcgcacgctgcgccggctgctgcaggagagagagctcgtggagcccctc
acgcccagtggggaggcccccaaccaggctctcctgagggtcttgaaggagacggagttc
aaaaagatcaaggtgctgggctctggcgcattcggcacggtgtacaagggtctctggaac
ccagaaggcgagaaggtcaagatccccgtggctatcaaggagttgagagaagccacgtct
ccaaaagccaacaaggaaattcttgatgaagcctacgtgatggccagcgtggacaaccct
cacgtgtgccgcctgctgggcatctgcctgacctccacagtccagctggtcacgcagctc
atgcccttcggctgcctcctggactatgtccgtgagcacaaggacaacatcggctcccag
tgcctgctgaactggtgtgtgcagatcgccaagggcatgaactacctggaagaccggcgt
ttggtgcatcgtgacctggccgccaggaacgtcctggtgaagacgccacagcacgtcaag
atcacagacttcgggctggccaagctgctgggcgccgaggagaaggaataccacgcggag
ggaggcaagcggctctgggagcaggccttgctgggagagtgggtagtgttgacgcctccg
ggggccaaaggcagtaaacgtgtcaccgtgtgggagctgatgacgttcgggtccaagcct
tatgatggcatcccggcgagcgaggtctcagccctgctggagaagggagagcgcctccca
cagccgcccatatgcaccatcgacgtctacatgatcatggtcaagtgtgagtggccgggg
ccgtccgcacgcgcgtggccgcacctggctctcagagggccttgccgtgcccggaaaggc
atcgctgcctggagccaaacaattgagaccttagagttccccaaagaagtgctgtcatat
tcttcacagcaggcactcgggtccaaaagcatgtgtcagtgctcccccagacattcttca
ggagacacttgcttgactcatcgagcatcgtga

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