Pteropus vampyrus (large flying fox): 105309400 Help Entry 105309400         CDS       T07815                                  Symbol ADCY4 Name (RefSeq) adenylate cyclase type 4   KO K08044   adenylate cyclase 4 [EC:4.6.1.1] Organism pvp  Pteropus vampyrus (large flying fox) Pathway pvp00230   Purine metabolism pvp01100   Metabolic pathways pvp01522   Endocrine resistance pvp04015   Rap1 signaling pathway pvp04020   Calcium signaling pathway pvp04022   cGMP-PKG signaling pathway pvp04024   cAMP signaling pathway pvp04062   Chemokine signaling pathway pvp04072   Phospholipase D signaling pathway pvp04081   Hormone signaling pvp04082   Neuroactive ligand signaling pvp04114   Oocyte meiosis pvp04211   Longevity regulating pathway pvp04213   Longevity regulating pathway - multiple species pvp04261   Adrenergic signaling in cardiomyocytes pvp04270   Vascular smooth muscle contraction pvp04371   Apelin signaling pathway pvp04540   Gap junction pvp04611   Platelet activation pvp04713   Circadian entrainment pvp04714   Thermogenesis pvp04723   Retrograde endocannabinoid signaling pvp04724   Glutamatergic synapse pvp04725   Cholinergic synapse pvp04727   GABAergic synapse pvp04742   Taste transduction pvp04750   Inflammatory mediator regulation of TRP channels pvp04911   Insulin secretion pvp04912   GnRH signaling pathway pvp04913   Ovarian steroidogenesis pvp04914   Progesterone-mediated oocyte maturation pvp04915   Estrogen signaling pathway pvp04916   Melanogenesis pvp04918   Thyroid hormone synthesis pvp04921   Oxytocin signaling pathway pvp04923   Regulation of lipolysis in adipocytes pvp04925   Aldosterone synthesis and secretion pvp04926   Relaxin signaling pathway pvp04927   Cortisol synthesis and secretion pvp04928   Parathyroid hormone synthesis, secretion and action pvp04934   Cushing syndrome pvp04935   Growth hormone synthesis, secretion and action pvp04970   Salivary secretion pvp04971   Gastric acid secretion pvp04972   Pancreatic secretion pvp04976   Bile secretion pvp05032   Morphine addiction pvp05163   Human cytomegalovirus infection pvp05166   Human T-cell leukemia virus 1 infection pvp05200   Pathways in cancer pvp05207   Chemical carcinogenesis - receptor activation pvp05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:pvp00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     105309400 (ADCY4)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     105309400 (ADCY4)    04371 Apelin signaling pathway     105309400 (ADCY4)    04020 Calcium signaling pathway     105309400 (ADCY4)    04072 Phospholipase D signaling pathway     105309400 (ADCY4)    04024 cAMP signaling pathway     105309400 (ADCY4)    04022 cGMP-PKG signaling pathway     105309400 (ADCY4)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     105309400 (ADCY4)    04081 Hormone signaling     105309400 (ADCY4)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     105309400 (ADCY4)   09144 Cellular community - eukaryotes    04540 Gap junction     105309400 (ADCY4)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     105309400 (ADCY4)    04062 Chemokine signaling pathway     105309400 (ADCY4)   09152 Endocrine system    04911 Insulin secretion     105309400 (ADCY4)    04923 Regulation of lipolysis in adipocytes     105309400 (ADCY4)    04912 GnRH signaling pathway     105309400 (ADCY4)    04913 Ovarian steroidogenesis     105309400 (ADCY4)    04915 Estrogen signaling pathway     105309400 (ADCY4)    04914 Progesterone-mediated oocyte maturation     105309400 (ADCY4)    04921 Oxytocin signaling pathway     105309400 (ADCY4)    04926 Relaxin signaling pathway     105309400 (ADCY4)    04935 Growth hormone synthesis, secretion and action     105309400 (ADCY4)    04918 Thyroid hormone synthesis     105309400 (ADCY4)    04928 Parathyroid hormone synthesis, secretion and action     105309400 (ADCY4)    04916 Melanogenesis     105309400 (ADCY4)    04925 Aldosterone synthesis and secretion     105309400 (ADCY4)    04927 Cortisol synthesis and secretion     105309400 (ADCY4)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     105309400 (ADCY4)    04270 Vascular smooth muscle contraction     105309400 (ADCY4)   09154 Digestive system    04970 Salivary secretion     105309400 (ADCY4)    04971 Gastric acid secretion     105309400 (ADCY4)    04972 Pancreatic secretion     105309400 (ADCY4)    04976 Bile secretion     105309400 (ADCY4)   09156 Nervous system    04724 Glutamatergic synapse     105309400 (ADCY4)    04727 GABAergic synapse     105309400 (ADCY4)    04725 Cholinergic synapse     105309400 (ADCY4)    04723 Retrograde endocannabinoid signaling     105309400 (ADCY4)   09157 Sensory system    04742 Taste transduction     105309400 (ADCY4)    04750 Inflammatory mediator regulation of TRP channels     105309400 (ADCY4)   09149 Aging    04211 Longevity regulating pathway     105309400 (ADCY4)    04213 Longevity regulating pathway - multiple species     105309400 (ADCY4)   09159 Environmental adaptation    04713 Circadian entrainment     105309400 (ADCY4)    04714 Thermogenesis     105309400 (ADCY4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105309400 (ADCY4)    05207 Chemical carcinogenesis - receptor activation     105309400 (ADCY4)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     105309400 (ADCY4)    05163 Human cytomegalovirus infection     105309400 (ADCY4)   09165 Substance dependence    05032 Morphine addiction     105309400 (ADCY4)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     105309400 (ADCY4)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     105309400 (ADCY4)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     105309400 (ADCY4) Enzymes [BR:pvp01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      105309400 (ADCY4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N CD52 Motif Other DBs NCBI-GeneID:  105309400 NCBI-ProteinID:  XP_011383834 UniProt:  A0A6P3RPK3 LinkDB All DBs Position Unknown AA seq 1077 aa AA seqDB search MPRLFSPRPPPSEDLFYETYYSLSQQYPLLLLLLVIVLSALLALLAVAWASGRELASDRG FLATVLCALGGFSLLLGLASREQRLQRWTRPLSGLVWAALLALGHGFLFTGGVVSAWDQV SFFIFVIFTTYAMLPLGMRDAAAAGLTSSLSHLLVLGLYLGPQPDSRPALLPQLAANAVL FLCGNVAGAYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMK AEIMARLQAGQGSRPESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATG VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITGATLALLGG AYAVEDVAMEHRDPYLRELGEPTYLVIDPRAEEEDEKGTAGGLLSSLEGPKMRPSLLMTR YLESWGAAKPFAHLSHVESPVSTSTPLPEKALASFGPQWSLDRSRTPRRLDDELDTGDAK FFQVIEQLNSQKQWKQSKDFNPLTLYFREKEMEKEYRLSALPAFRYYAACTFLVFLSNFI IQMLVTNRPPALAITYSITFLLFLLLLFACFSEHLTRCVLKGPKMLHWLPALSGLVATRP GLRVALGTATILLVFSMAITSLFFLPAASNCPFRVPNVSSEAFNLSWELPGSLPLISIPY SMHCCVLGFLSCSLFLHMSFELKLLLLLLWLVASCSLFLHSHAWLSDCLVARLYLGPLDS RPGVLKEPKLMGAISFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEREETEMMENLTRL LLENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESNINHEGLECLR LLNEIIADFDELLSKPKFSGVEKIKTICSTYMAATGLNATSGQDAQQDAERSCSHLGTMV EFAVALGSKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMEST GVLGKIQVTEETARALQSLGYTCYSRGVIKVKGKGQLCTYFLNTDLTRVGPPSATLG NT seq 3234 nt NT seq  +upstreamnt  +downstreamnt atgccccgcctcttcagtccccggccaccgcccagcgaagacctcttctatgagacctac tacagtctgagccagcagtacccactgctgctactgctgctggtgatcgtgctctccgca ctcctggcgttgctcgctgtcgcctgggccagtggcagggagctggcttcggacaggggc ttcctggccacagtgctgtgcgcgctgggcgggttctcattgctgctgggcctggcttcc cgcgagcagcgactgcagcgctggacgcgtcccctctccggcctcgtgtgggcagcgtta ctcgcgctaggccacggcttcctgttcactggaggcgtagtgagcgcctgggaccaggtg tcctttttcatctttgtcatcttcaccacgtatgccatgctgcccttgggcatgcgcgac gccgccgccgcgggcctcacttcatcactctcacacctgctggttctcgggctgtatctt gggcctcagccagactcacgaccggcgctgctgcctcagttggcagcaaacgcggtgctg ttcctgtgcgggaacgtggccggggcgtatcacaaagcgctgatggagcgggcgctgcgg gccaccttcagagaggcgcttagttccctgcactctcgccggaggctggacaccgagaag aagcatcaggaacaccttctcttgtccatccttcctgcctacttggcccgagagatgaag gcggagatcatggcaaggctgcaggctggacaggggtcacggccagagagcaccaacaac ttccacagcctttatgtaaagaggcaccagggagtcagcgtgctgtatgctgacatcgtg ggcttcacgcggctggccagtgaatgctccccaaaggagctggtgctcatgctcaacgag ctctttggcaagttcgaccagattgccaaggagcatgaatgcatgcggatcaagatcctg ggagactgttactactgtgtctctgggctgccgctctcactaccagaccacgccatcaac tgtgtgcgcatggggctggacatgtgccgggccatcaggaaattgcgggcagccaccggt gttgacatcaatatgcgcgtgggcgtgcactcgggcagcgtgctctgcggagtcatcggg ctgcagaaatggcagtatgatgtctggtcccatgatgtcacactggccaaccacatggag gcaggtggcgtgccaggacgagtgcatatcacaggggctaccctggccctgctaggagga gcttacgctgtggaggatgtagccatggaacaccgggacccataccttcgagagctaggg gagcctacctacctggtcatcgatccccgggccgaggaggaggatgagaagggcactgcg ggagggttgctgtcctctctcgaaggtcccaagatgcgtccatcactgctgatgacccgc tatctggaatcctggggtgcagccaagccttttgcccatctgagccacgtagagagccct gtgtccacctccacccctctgccggagaaagccctggcttccttcggcccccagtggagc ctggaccggagccgtacccctcggagactagatgatgaactggacaccggggatgccaag ttcttccaggtcatcgaacagctcaactctcagaaacagtggaagcagtcaaaggacttc aacccactgacattgtacttccgagagaaggagatggaaaaagagtatcgactctccgca ctccctgccttcagatactatgcagcctgcaccttcctggtttttctctccaacttcatc atccagatgctggtgacaaacaggcccccagccctggccatcacctatagcatcaccttc ctcctcttcctcctcctcctcttcgcctgcttctcagagcacctgacgaggtgtgttttg aaaggccccaagatgctgcactggcttcccgcactgtctggcctggtggccacacgtccc ggactgcgggttgccctgggcactgccaccatcctccttgtcttttccatggccattacc agcctgttcttcttaccggcagcatcgaactgccctttccgggtgcccaatgtgtcctct gaggctttcaacctctcctgggagctccctgggtccttgcctctcatcagcatcccatac tccatgcactgctgtgtgctgggtttcctctcctgctccctctttctgcacatgagcttt gaactgaagctgctgctgctcctgctgtggctggtggcctcctgctccctcttcctgcac tcccatgcctggctgtcggattgcctcgttgcccgcctctatctcggccccttggactcc aggccaggggtgctgaaggagcccaaactcatgggagctatctccttcttcatcttcttc ttcacactccttgtcttggctcggcagaatgagtattattgccgcctggacttcctgtgg aagaagaaactgaggcaggagcgggaagagacagagatgatggagaacctgactcggctg ctcttggagaacgtgcttcctgcgcacgtggccccccagttcattggccagaaccggcgc aacgaggacctctaccaccagtcctacgagtgtgtctgtgtcctcttcgcctcagtccca gactttaaggagttttactccgaatctaacatcaaccatgaggggctagagtgtctgcgg ctgctcaatgagatcattgctgattttgatgagctgctctctaagcccaagttcagtggg gtggaaaagatcaaaacgatctgcagcacctacatggcagctacaggcttaaatgccacc tctggacaggatgcacagcaggatgctgagcgaagctgcagccaccttggcaccatggtg gagtttgcggtggcccttgggtctaagctggatgtcatcaacaagcactcattcaacaac ttccgcctgcgtgtggggttgaaccatggacctgtggtggctggagtgataggggcccag aagccacaatatgacatctggggcaacacagtgaatgtggccagccgcatggagagtaca ggagtcctgggcaagatccaagtaactgaggagacagcccgtgccctgcagtccttaggt tacacctgctacagccggggtgtcatcaaggtcaaaggcaaagggcagctgtgcacctac ttcctgaacacagatttgacacgagttggacctccttcagccaccctgggctga

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