Pleurodeles waltl (Iberian ribbed newt): 138252019
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Entry
138252019 CDS
T10800
Symbol
GBA2
Name
(RefSeq) non-lysosomal glucosylceramidase isoform X1
KO
K17108
non-lysosomal glucosylceramidase [EC:
3.2.1.45
]
Organism
pwl Pleurodeles waltl (Iberian ribbed newt)
Pathway
pwl00511
Other glycan degradation
pwl00600
Sphingolipid metabolism
pwl01100
Metabolic pathways
pwl04382
Cornified envelope formation
Brite
KEGG Orthology (KO) [BR:
pwl00001
]
09100 Metabolism
09103 Lipid metabolism
00600 Sphingolipid metabolism
138252019 (GBA2)
09107 Glycan biosynthesis and metabolism
00511 Other glycan degradation
138252019 (GBA2)
09150 Organismal Systems
09158 Development and regeneration
04382 Cornified envelope formation
138252019 (GBA2)
Enzymes [BR:
pwl01000
]
3. Hydrolases
3.2 Glycosylases
3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
3.2.1.45 glucosylceramidase
138252019 (GBA2)
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Paralog
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Motif
Pfam:
GH116_catalytic
Glyco_hydr_116N
HvfC_N
DUF5127
Motif
Other DBs
NCBI-GeneID:
138252019
NCBI-ProteinID:
XP_069061800
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Position
1_2:1340327930..1340495578
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AA seq
853 aa
AA seq
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MPYRGGGPRETPGLMDSYEGAVDGHRVPAAGWRLCLAHQFLEKRRPFSLRDASFRTMVQH
LPLGVRYLFWWFRKTYVEKKAPFIDMLNSIPLRQIYGAPLGGFGGGTITRGWRGEFCRWQ
LSPGLYHYETVIEDQFTVCIRRNGQTVYQQVLSVEKPHTLQGWNWGFCGRHAFYHALYPR
AWTVYHLPGQNVTLTCRQVSPIIPHDYKDTSLPVGIFVWEIENGNEEDIEITIMFTMRNG
AGTPSDKDGGHWNEPFCVQEEGEKISGVLLHHVAAVNPYTLSVSARSTVGTDVTYLTSFN
PDGFGHDVWRDLMEDGRLECPKGPSAPTMKGAMTAAAIAAKCTVPARGHGTLEFCLAWDM
PRIYFGSQEKEHLRRYTRFFSSNGDAGPALSHYALTHYKEWEQKITEWQEPILANSTYPS
WFKSALFNELYFVADGGTVWLEVPSETSDSDLMGAETGRLPDLPRVLREYGRFAYLEGQE
YRMYNTYDVHFYASFALIMLWPELEISLQYDMALAVLKEDSRRRQHLMNGQVSMVKTKNI
VPHDVGDPDDEPWERLNAYLIHDTANWRDLNLKFVLQVYRDYYLTKNETYLRDMWPVCQA
VMDSEQKFDTDGDGLIENSGSADQTYDGWMVTGPSAYCGGMWLASVCMMCKMAEILNDDV
VLHKYSCILEKGKSAFERLLWNGKYYNYDSSRSVYANSVMSDQCAGQWFLRASGLGEGQY
EVFPREHIRSALQTIFELNVKRFGGGTMGAVNGMRPDGKIDTSSVQSDEVWVGVVYGLAA
TMIQEGLVEEGFETAEGCYRTVWERLGMAFQTPEAYCEKNIFRSLAYMRPLSVWGMQLAL
QCRAKETPPPQGK
NT seq
2562 nt
NT seq
+upstream
nt +downstream
nt
atgccctaccggggtgggggcccgagggagacccccggcctcatggacagctacgagggc
gcagtggacgggcaccgggtccccgccgcgggctggcggctctgcctggctcatcagttc
ctggagaagcgcaggccgttctctctgcgcgatgcttccttcaggaccatggtccagcac
ctcccgctgggggtcagatatctattctggtggttccgaaagacctatgtcgaaaaaaaa
gctccatttattgacatgctgaattccatcccactgcgccagatatacggagccccgctg
ggtggatttgggggaggcaccatcacccgtggctggcggggagagttctgtcgatggcag
ctcagtccaggactatatcattacgaaacagtgatagaagatcagttcacagtttgcatt
cgcaggaatgggcagactgtctatcagcaggtcctgtctgtggagaaacctcacaccctt
caaggatggaactggggcttctgcggccggcacgccttctaccatgcactgtacccccgt
gcctggactgtctaccatctaccagggcagaatgtgacactcacctgccggcaggtgtct
cctatcatccctcacgactacaaggacacaagccttccagttgggatttttgtctgggag
atagaaaatggaaatgaagaagacattgagataaccatcatgtttaccatgaggaatggg
gctggaaccccgagtgacaaagatggagggcactggaatgagccattctgcgtgcaggag
gagggggagaaaatctctggtgttcttttgcatcacgttgcagctgttaacccatacacc
ctgtctgtatccgcgagatcaacggttggcactgatgttacctacttgacatctttcaac
cccgacggcttcgggcatgatgtgtggagagacctcatggaggacggtcgtcttgagtgt
cccaaaggtccaagcgcacccacaatgaaaggggcgatgactgcagctgcgatcgctgct
aaatgcacagtaccagcccggggacatggaacgctggaattctgtttagcctgggatatg
ccgcgcatttattttgggtcacaggagaaggaacacttgaggcgctacacaaggttcttt
agcagcaatggggatgcaggcccagccttatcccattatgcacttacgcactacaaggag
tgggagcaaaagattactgagtggcaggaacccatcctggcaaacagcacttatccatcc
tggtttaaatcagcgcttttcaatgagttgtactttgtggctgatggagggactgtgtgg
ttggaggttcccagcgagaccagcgacagcgatttgatgggtgcagagacgggcagactg
ccagatctcccaagagtgctgcgggaatatggacgctttgcctacctggaaggccaggag
tacaggatgtacaacacctatgatgtgcacttttatgcttcgtttgccctcattatgctg
tggcctgagctagagatcagccttcagtatgatatggccctggcagtgctaaaggaggac
agcaggcgcaggcaacacctgatgaatgggcaggtatcaatggtgaaaaccaaaaacatc
gtcccacatgatgtgggagatccagatgatgagccctgggagagactgaacgcgtacctg
atccatgacacagcgaactggagggatctgaacttgaagtttgttctccaggtttacaga
gattactacctcaccaagaatgagacctacctgagggacatgtggccggtctgccaggct
gtgatggattcagagcagaagtttgacactgatggggatggtctgattgagaactcgggc
tcagctgatcagacgtacgacggatggatggtgacaggaccaagtgcatactgtgggggc
atgtggctcgcctctgtctgcatgatgtgcaagatggccgaaatcttaaacgatgatgtg
gttcttcacaagtattcctgtatcctggagaagggaaagagtgcatttgaaaggctcctg
tggaatggtaaatattacaactacgacagcagcagaagtgtgtacgcgaacagtgtgatg
tcagaccagtgcgccggccagtggtttctgcgtgcctctggtttgggagagggacagtat
gaggttttccccagagagcacatcagaagcgccctacagactatctttgaactgaatgtc
aagcggtttggtggtggaaccatgggagctgtgaatgggatgcgaccagacgggaagata
gacacctccagcgtgcagtcggatgaagtttgggttggagttgtgtatggtctcgctgcc
accatgattcaggagggtcttgtggaggagggctttgagaccgcagagggctgttataga
acagtatgggagcgccttggtatggcctttcagacaccagaagcatactgtgagaagaac
atcttccggtccctggcttacatgcgacctctcagtgtatggggcatgcagcttgcactg
cagtgcagagctaaagagactcccccaccacagggaaagtaa
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