KEGG   Pleurodeles waltl (Iberian ribbed newt): 138259923
Entry
138259923         CDS       T10800                                 
Symbol
PLCB3
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
pwl  Pleurodeles waltl (Iberian ribbed newt)
Pathway
pwl00562  Inositol phosphate metabolism
pwl01100  Metabolic pathways
pwl04020  Calcium signaling pathway
pwl04070  Phosphatidylinositol signaling system
pwl04081  Hormone signaling
pwl04082  Neuroactive ligand signaling
pwl04261  Adrenergic signaling in cardiomyocytes
pwl04270  Vascular smooth muscle contraction
pwl04310  Wnt signaling pathway
pwl04371  Apelin signaling pathway
pwl04540  Gap junction
pwl04621  NOD-like receptor signaling pathway
pwl04912  GnRH signaling pathway
pwl04916  Melanogenesis
Module
pwl_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:pwl00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    138259923 (PLCB3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    138259923 (PLCB3)
   04371 Apelin signaling pathway
    138259923 (PLCB3)
   04020 Calcium signaling pathway
    138259923 (PLCB3)
   04070 Phosphatidylinositol signaling system
    138259923 (PLCB3)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    138259923 (PLCB3)
   04081 Hormone signaling
    138259923 (PLCB3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    138259923 (PLCB3)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    138259923 (PLCB3)
  09152 Endocrine system
   04912 GnRH signaling pathway
    138259923 (PLCB3)
   04916 Melanogenesis
    138259923 (PLCB3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    138259923 (PLCB3)
   04270 Vascular smooth muscle contraction
    138259923 (PLCB3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pwl04131]
    138259923 (PLCB3)
Enzymes [BR:pwl01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     138259923 (PLCB3)
Membrane trafficking [BR:pwl04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    138259923 (PLCB3)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    138259923 (PLCB3)
SSDB
Motif
Pfam: PI-PLC-X PLC-beta_C PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like C2
Other DBs
NCBI-GeneID: 138259923
NCBI-ProteinID: XP_069064007
LinkDB
Position
9:753806931..754357049
AA seq 1266 aa
MAGARPGVHALQLKPISVHETLKKGSKFIKWDEEPTSRNLITLKVDPQGFFLYWSGPNME
VDVVDITLIRDTRTGRYAKTPKDPKIRDVLGFSSPETRPEDKLVTVVYGPDMVNISFLNF
MAVQEDTAKIWTEELFKLATNILAHNASRNTFLHKAYTRLKLQVNQDCRIPVKNILKMFS
ADKKRVETALESCGLNFNRSESIKPDEFTLEIFERFLNKLCLRPDIDKILLELGAKGKPY
LTLDQLMDFLNQRQRDPRLNEILYPPLKKDQVRLLIEKYEPNRQFLERDQMSMEGFSRFL
GGEENSIVPPDKLDLSDDMTQPLSNYFINSSHNTYLTAGQLTGNSSVEMYRQVLLTGCRC
IELDCWKGRPQDEEPFITHGFTMTTEISFKEVIEAIAESAFKTSPYPVILSFENHVDSAK
QQAKMAEYCRTIFGDALLIDPLEKYPLQAGVALPSPQELLGRILVKNKKRRQHHCKSYDG
SLKKRPVEQTSSSYSTYSTYSDSSSVGDLPSPNLGTSFTDQSDSSNVLSNGEEKLPKLEP
RKSIDREAESDEEEEEEQMELKKPTTDEGTASSEANATEEMSTLVNYVEPVKFKSFDVAS
KRNRYFEMSSFVETKGLEQLTKSPLEFVEYNKKQLSRIYPKGTRVDSSNYMPQVFWNAGC
QMVALNFQSLDLPMQLNMGIFEYNRRCGYLLKPEFMRRMDKHFDLFTEDIVDGIVANTVK
IKIISGQFLSDKKVGIYVEVDMFGLPIDTKRKYRTRTSQGNSFNPVWDEECFVFQKVVLP
TLASLRIGVFEEGGKFVGHRILPVSAIRPGYHYICLRNESNQPLCLPALLVYTEVNDYIP
DDHQDYAYALTDPIKHVSHMDQRAKQLIALLGDSEQGNIEKPKQLPKPGGRPSPTPGPLP
RPEPIQVSVGSPSLTNTGQRDDLIATILTEVSAQSVEELKQHKAYVKLVRKQYKELKELK
KKHMKRISALNKEQNSRINEFQSDSLRRSIKIENKLKYSRRGLNSSSEDMLRELDSLQRE
LNQKRLQLQEGQMRELLQVREQQHKIERDKKLEFLDQVVHKLREVAAECQAAQLKKLKEV
NEREKKELQKILDRKRLNSITETKSRDKQKKEAELSEINRRHITESVTSIRRLDEAQQLR
RDKLINSQKEIDLRIKEEELRLREQLDRDYAAETSQLQQEIRRYLQDELDGKLDSASMAD
SLNGHTPPSRGPDSPLPRGPPSAQSTPSSIARSLSNWRSDHSLDISTPSLTDAVGPLNHS
DETTVL
NT seq 3801 nt   +upstreamnt  +downstreamnt
atggccggggcccgtccgggggtgcacgctcttcagctgaagcccatttctgtgcacgag
accctcaagaagggcagcaagttcatcaaatgggacgaggaacctacaagccgcaaccta
atcaccctgaaggtggatccccaggggtttttcctgtactggagcgggccaaacatggag
gtggacgtggtggatatcaccttaataagggacacaaggacaggccgatatgcgaagaca
cccaaggaccccaagatccgggatgtgctgggattctcgagtcccgagaccaggcctgag
gacaagttggtgacggtggtgtatggcccggacatggtgaatatcagcttcctgaacttc
atggcggtgcaggaggacactgctaagatctggaccgaggagctgtttaaattggcaaca
aacatcctggcacacaatgcatctcgaaacaccttcttgcacaaagcctacactaggctc
aagttacaggtgaaccaggactgcaggattccagtgaagaacatcctgaagatgttctcc
gccgacaagaaacgcgtagagactgccctggagtcctgtggtctcaatttcaaccggagt
gagtctatcaagccagatgagttcacactggagatctttgagaggttcctgaacaagctc
tgtctgaggccagacattgataagatcttgctggagctgggggccaagggaaagccgtac
ctgactctagaccagctgatggacttccttaaccagcggcaacgagatcctagactcaat
gagatcctgtatccaccactgaagaaggaccaggtgcggctgctcatcgaaaagtatgag
cccaatcgccagttcctggagcgagatcaaatgtcaatggaaggctttagccggttcctt
ggcggggaagagaacagcattgtgcccccagacaagcttgatcttagcgacgatatgaca
cagcctctcagcaactacttcatcaactcatcccacaacacttacctcactgctggacag
ctgacagggaactcttctgttgagatgtaccgacaggtcctgcttactggttgccgttgc
attgagctggactgctggaagggaagaccacaagatgaagagccattcatcacccatggc
ttcaccatgaccacagaaatttccttcaaggaggtgattgaagcgatcgccgagagtgct
ttcaagacctccccatatcctgttatcctctcttttgagaatcatgttgattctgccaag
caacaagctaagatggcggaatactgccgaaccatctttggtgatgccctgttaatcgac
cctctcgagaaatatccgttgcaagccggcgttgccctgcccagccctcaagagctgctt
ggcaggatcctggtgaagaacaagaagaggcggcagcaccactgcaagtcatacgatggc
agtctgaagaagcgccctgtagagcagacatcaagtagttatagtacctacagcacctac
agcgactcctccagtgtgggagatctgccctcgccaaacctaggaacgtccttcactgac
cagtctgattccagcaatgttctctccaatggagaagagaagctgcccaagttagagcca
agaaagtccattgatcgggaagcagaaagtgatgaagaggaggaagaagaacaaatggag
ctcaagaaacccaccacagatgagggaacagcaagcagtgaggccaacgccaccgaagag
atgtccacccttgtcaactatgtggagcctgtcaagttcaaatcctttgatgtggccagc
aaacgtaataggtacttcgagatgtcatcttttgttgaaacgaagggactggagcagctc
accaaatcccctctggagtttgtggaatataacaagaagcaacttagccggatctacccc
aagggtacacgtgtggattcctccaactacatgccacaggtcttctggaatgctggttgc
cagatggtggcgctcaacttccagtcgcttgatctcccaatgcagttaaatatggggatc
tttgagtacaatcggcgctgcggctacctcctgaagccagagttcatgcggcgaatggac
aaacacttcgacctttttactgaagacattgtggatggaattgtggccaacacagtgaaa
atcaagataatttctggccagttcctctcggataaaaaggttggcatttatgttgaggtg
gatatgtttggacttccaattgacactaagcgcaagtaccgcaccaggacatcacaaggg
aactcctttaaccctgtctgggatgaggagtgctttgtctttcagaaggtagtgctaccg
acgctggcctcactccgtattggagtctttgaagaaggtgggaaatttgtgggtcatcgc
atcctgccagtgtccgctatcagaccaggatatcactatatttgtctgcgcaatgagagt
aatcagcccctttgtctgcccgctctcctggtctacactgaagttaatgactacatccca
gatgaccatcaagattatgcttacgcccttaccgatcccattaaacacgtcagccatatg
gatcagcgagcaaagcagcttatagcgctcctgggagatagcgagcaaggaaacattgaa
aaaccaaaacaactaccaaaacccggagggagaccttcaccgacacctggaccactgcct
aggcctgaacctatccaagtatctgtaggcagccctagtttgacaaacacaggccagagg
gatgatctcatcgcaaccattctgacagaggtgagcgcgcagtcagtggaggagctgaag
cagcacaaggcgtatgtgaagctggtgaggaagcaatataaggagctgaaggagctgaag
aagaagcacatgaagaggatctcagccctgaacaaggagcagaacagccgcatcaacgag
ttccagagcgacagcctacggcgctccatcaagattgagaacaagctcaagtactctagg
cgagggttaaacagctcgtcggaggacatgttgagggagctagacagcctgcagcgggag
ctcaaccagaagagattgcagctgcaggaggggcagatgcgggagctgttgcaggtgcga
gagcagcagcataaaattgagagggacaagaagctcgagttcttggaccaggtcgtgcat
aagctgagggaagtggcggctgagtgccaggcagcccagctcaagaagctgaaggaagtg
aatgagagagagaagaaagagctacagaagatcctggaccgcaagcggctcaacagcatc
actgagactaaatcccgagataagcagaagaaggaagcggaactttctgaaatcaatcgg
cggcacattacagagtcagtgacatccatccgacggctggatgaggctcagcagttgcgc
cgggataaactcatcaacagccaaaaggagattgatttgcggatcaaggaggaagaatta
aggcttcgggaacagcttgacagggactatgcagcagaaaccagccagctacaacaggag
atcaggcggtacctgcaggatgagcttgatgggaagctggacagcgccagcatggcagat
agcctgaatgggcatacgcccccatcgcgtggccctgacagccctctccctcgcgggcca
ccctcagcccagagcactccatcttcaatcgccaggagcctgtcgaactggcggagtgac
cacagcctcgacatcagcaccccgtcactgacggacgctgtcgggccccttaaccacagt
gacgagaccacagtgctgtga

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