Pleurodeles waltl (Iberian ribbed newt): 138267570
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Entry
138267570 CDS
T10800
Symbol
HSD17B2
Name
(RefSeq) 17-beta-hydroxysteroid dehydrogenase type 2
KO
K13368
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:
1.1.1.62
1.1.1.239
]
Organism
pwl Pleurodeles waltl (Iberian ribbed newt)
Pathway
pwl00140
Steroid hormone biosynthesis
pwl01100
Metabolic pathways
Module
pwl_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
pwl00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
138267570 (HSD17B2)
Enzymes [BR:
pwl01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
138267570 (HSD17B2)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
138267570 (HSD17B2)
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Motif
Pfam:
adh_short
adh_short_C2
KR
DUF1776
Motif
Other DBs
NCBI-GeneID:
138267570
NCBI-ProteinID:
XP_069072721
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Position
12:154105126..154380674
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AA seq
389 aa
AA seq
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MPPLEILRLLFVGISAVCGGWVLYRLRGKQVQKEGRTACALLLIAALSACSLPAHVGLPL
FCGACLLSALCVPPQDMLPAQGKAVLITGCDSGLGYALAKHLDQLGFQVFAGVLNKKGEG
ADELRNACSPRLLLIQLDITSCEEAKKAYIEVKSSLKDSGLWGIIHNAGVLGYVGDGELL
PLGVYKTCMDVNFFGAVRISKTFFPLLRKAKGRLISISSMAGHAPLPGFAAYGASKAALS
MFSAVMRQELSKWGVKVSAIYPGGFRTGIYGSQESWSNQDGKILYNLVDDVKEDYGEDYI
RTMKECYKLMLSDASPDLSPFLYDVAHALLATKPHNTYTPGRCAYIIPCIFRYFPVWMYD
GLARKLFGSYNMLSPRALRPLQTPNKKHN
NT seq
1170 nt
NT seq
+upstream
nt +downstream
nt
atgcccccattagagatcctgagactgctctttgtgggcatcagtgcagtctgtggaggt
tgggtgctgtatagactccgcgggaagcaggtgcagaaggaggggcggactgcgtgcgcc
ctgctcctgatagcagcgctgtctgcctgctccctgcccgctcatgtggggctgcctcta
ttctgcggggcatgcctgctctcggcgctctgtgtgcccccacaggatatgctaccggca
caagggaaggcggtgctcatcacaggttgtgactctgggttaggctatgcattagcgaag
catctggatcagttgggattccaagtgtttgctggagttctgaataagaaaggagaaggt
gcagatgaattaagaaatgcctgttccccaagactcttgcttatccagttggatataacc
agctgtgaagaagcaaaaaaagcatacattgaagtcaagtcatctttgaaagattcaggc
ctctgggggattatccacaatgctggagtgcttggatatgttggagatggagaactgcta
cctctcggtgtttacaaaacctgtatggatgtgaacttttttggagcagttcgtatttct
aaaaccttcttcccgttgctccggaaggccaaggggaggctgatcagcatttccagtatg
gcaggacatgctccactccctgggtttgcagcatatggtgcttcaaaggcagctctatct
atgttttccgcagtaatgagacaggagctttctaaatggggcgttaaagtatctgcaatt
tatccaggtggcttcaggacaggtatttatggatcgcaagaaagctggtctaaccaagat
gggaaaattctgtacaatcttgtggacgacgtgaaggaggactacggagaggactacatt
aggacaatgaaggagtgctacaagctgatgttgagtgatgcctctcctgatctctctcct
ttcctctatgatgtggctcatgcacttctagccacgaagccacacaacacatacacacct
gggagatgtgcctacataatcccatgtatttttcgctactttcctgtttggatgtatgat
ggtcttgccaggaagttgtttggcagctacaatatgctgtctcccagagccctacggccg
cttcagacccctaacaaaaaacacaattag
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