Pleurodeles waltl (Iberian ribbed newt): 138282431
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Entry
138282431 CDS
T10800
Symbol
ROCK1
Name
(RefSeq) rho-associated protein kinase 1
KO
K04514
Rho-associated protein kinase 1 [EC:
2.7.11.39
]
Organism
pwl Pleurodeles waltl (Iberian ribbed newt)
Pathway
pwl04270
Vascular smooth muscle contraction
pwl04350
TGF-beta signaling pathway
pwl04510
Focal adhesion
pwl04520
Adherens junction
pwl04530
Tight junction
pwl04810
Regulation of actin cytoskeleton
Brite
KEGG Orthology (KO) [BR:
pwl00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
138282431 (ROCK1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
138282431 (ROCK1)
04520 Adherens junction
138282431 (ROCK1)
04530 Tight junction
138282431 (ROCK1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
138282431 (ROCK1)
09150 Organismal Systems
09153 Circulatory system
04270 Vascular smooth muscle contraction
138282431 (ROCK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pwl01001
]
138282431 (ROCK1)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
pwl03036
]
138282431 (ROCK1)
Enzymes [BR:
pwl01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.39 ROCK-subfamily protein kinase
138282431 (ROCK1)
Protein kinases [BR:
pwl01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
138282431 (ROCK1)
Chromosome and associated proteins [BR:
pwl03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
138282431 (ROCK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Rho_Binding
PH
C1_1
Pkinase_C
APH
PH_9
Motif
Other DBs
NCBI-GeneID:
138282431
NCBI-ProteinID:
XP_069076092
LinkDB
All DBs
Position
2_2:complement(498968874..500343727)
Genome browser
AA seq
1362 aa
AA seq
DB search
MSTTGENLEARLGRMDAMLRDPASQVNTDCLLDGLDALVYELDFPALRKNKNIDNFLSRY
KDTISKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKATKKVYAMKLLSKLEMIKRSDSA
FFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYT
AEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPD
YISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTF
PDDSDISKDAKNLICAFLMDREVRLGRNGVEEIKRHLFFKNDLWTWDNLRDTVAPVVPDL
SSDVDTSNFDDLEEDKGEEETFPIPKAFVGNQLPFVGFTYYSNRQYLFVDGTSQDDNRGG
SKVEKNLLENLQKNIYQLEEQLHNEMQLKDEMEQRCRLSNIKLDKIMKELDEEGNQRKNL
ESSVSQVENQNMMLQHRINEYQRKVEHENERRRNVENEVSTLKEQLEDFKKRSQNSQITN
EKIIQLQKQLDEASDFLRTESETSARLRKSQAETSKMVTHLETLNRELQERCRVLENTKV
QVEKEFYQQQAVLEAERRDRSHGSEMIGDLQARITSLQDEVKHIKNNLERVEAERKQTQE
SLNLSEKERNNLEIDLNYRLKTLQQQLEQEVTEHNVTKARLSDKHQSLEEEKSVAMCEME
RKVKMERAAKEKAESRRVEIEKQCSMLELDLKQSRQKMEHLVQQKERLEDDFKHLTHQLD
QETNKRVSIQNELKVQAFEIDNLKGTEKQQKQEINTLLEAKRLLEFELAQMTKQYRGNEG
QMRELQDQLEAEQYFSTLYKTQVKELKEEIEEKSKQNQELQKKIHELQNEKETLTAQLDL
AITKAESEQLARGLLEEQCFELTQENKKAATRSRQDVSDKDQTVRKLEETTSMLTKDVQT
LRKENVLLLEKARKAEEEYRLKKEEEINHIKQAYEKSINNERTLKTQAVNKLAEIMNRKD
FKLDKKKASSQDLRKKERENRKLQLDLNQEKEKFNQMVSKYQKELNDMQAQLAEESLCKM
DLQMQLDSKESDIEQLRAKLSDLQLRMDSTSVSSLQTDEADGIVGESRVEGWLSIPNKGN
IKRHGWKKQYVVVSSKKILFYNDEQEKEQSNPSMVLDIDKLFHVRSVTQGDVYRAETEEI
PRIFQILYANEGECRKDVETEPAQPAERTNFLNHKGHEFIPTLYHFPASCEACTKPLWHV
FKPPPALECRRCHVKCHKDHLDKKEEVITPCKVSYDVTSARDMLLLACSQDEQKKWVTHL
VKKIPKAPPTEFVRASPRTVSKRSTANQSFRKAVKNASGKAS
NT seq
4089 nt
NT seq
+upstream
nt +downstream
nt
atgtcaaccaccggagagaacttggaggcccgtttggggcggatggatgccatgctgcgg
gatcctgccagtcaagtcaataccgactgtctgctggatggattggatgccttagtgtac
gagttggattttcctgccttgaggaaaaacaaaaacattgataactttctaagcagatat
aaagacacaataagtaaaataagagatttgcgcatgaaagctgaagattatgaagtagtg
aaggtgattggcagaggagcttttggtgaagttcagttggtaagacataaagcaactaaa
aaagtgtatgctatgaagcttctgagcaaactggagatgataaaacgatcagattctgca
tttttctgggaagaaagggacatcatggcctttgcaaatagcccatgggttgtccagttg
ttttatgcgttccaagatgaccgctatctttacatggtaatggagtacatgcctggtggg
gatcttgtgaatttaatgagcaactacgatgtgcctgaaaaatgggccaggttttataca
gctgaagttgtgcttgcattggatgcaattcactcaatgggattcattcacagagatgta
aagcctgataatatgctgcttgataaatctggccatttgaaacttgcagattttggtaca
tgtatgaaaatgaataaggaaggaatggtacgttgtgatacagctgtgggaacaccagac
tacatatcccctgaggtgctaaaatcacaaggaggggatggttactatggacgggaatgt
gactggtggtctgttggagttttcttatatgaaatgcttgtaggtgatacaccattttat
gctgattctttggtaggaacttacagtaaaattatgaaccataagaattcacttacattt
cctgatgatagtgatatatcaaaagatgcaaagaatcttatttgtgccttccttatggac
agggaagtgaggttaggaagaaacggtgtcgaagaaatcaaacgccatctattctttaaa
aatgatctgtggacgtgggataatctaagagacactgtagcacccgttgtgcctgatcta
agcagcgatgttgataccagtaactttgatgacctggaagaggacaaaggagaagaagaa
acatttcctatcccgaaagcttttgttggcaaccaactaccttttgtaggattcacatac
tatagcaatcgccagtatttatttgttgatgggacaagtcaagatgacaacagaggtggt
tcaaaagttgaaaaaaatctgctggaaaaccttcagaaaaacatctatcagcttgaagaa
cagcttcacaatgaaatgcagttgaaagatgaaatggagcaacgttgcaggttatctaat
ataaaattagacaagatcatgaaagaattggatgaagagggcaatcaaaggaaaaactta
gaatcttctgtgtcccaagttgagaatcaaaatatgatgctgcagcatagaataaatgaa
tatcaaaggaaggtggaacacgagaatgaaagaaggcgaaatgtagaaaatgaagtttca
acattaaaagaacaattagaggactttaaaaaaaggagtcagaattcgcaaattacaaat
gagaagataattcagttgcaaaagcaactggacgaagccagtgactttttaaggacagaa
tctgaaacatcagcgagactgcgaaaaagccaagcagaaacgagtaagatggtgacccac
ttagaaacacttaacagggagctgcaagagaggtgcagagtgttagaaaacaccaaagta
caggtggaaaaagagttttaccaacaacaagcagttttggaagctgaacgaagggacaga
agtcatgggtctgaaatgattggtgatctacaagctcgaattacttctttacaagatgaa
gtgaaacatatcaaaaataatcttgaaagagttgaagctgagagaaagcagacacaggag
agcctcaatctttctgaaaaggaaagaaataatttagaaatagaccttaactaccggctg
aaaacattgcagcagcaattggagcaggaagtaacagagcataacgtgaccaaagcacgg
ttaagtgacaagcatcagtcacttgaggaagaaaaatcggtcgcaatgtgtgaaatggag
cggaaagtgaagatggaaagggcagcgaaggaaaaggctgaaagtcgcagagtagagatt
gaaaaacaatgttcaatgttggaactggacctcaagcagtctcgtcagaagatggagcat
cttgttcaacagaaagaaagactagaagatgatttcaaacatttaactcaccagctggat
caggaaacgaacaagagggtatcgatacaaaatgagctaaaagtgcaagcttttgaaata
gataacttaaagggtactgaaaagcagcaaaagcaggagataaacacattgctggaagca
aaaagattgttggaatttgagctggctcaaatgaccaagcagtacagaggaaatgaaggt
cagatgcgagagcttcaagatcaacttgaggctgagcagtatttttcaacactttataaa
actcaggttaaggagttgaaggaggaaattgaagaaaaaagtaaacagaaccaagagctt
caaaagaaaatacatgagctgcaaaatgaaaaggagactctaactgcgcagttggatctg
gctataaccaaagctgaatctgaacaactcgctcgaggactcttagaggagcagtgtttt
gaattgacgcaagagaacaaaaaagcagctacacggagtaggcaagatgtttctgacaaa
gaccagactgttcgtaagctggaggaaacaactagtatgttaaccaaagatgttcaaaca
ctaagaaaagaaaatgtactgcttcttgaaaaggcaagaaaagctgaagaagaatatcgg
ttgaagaaagaagaagaaataaatcatattaaacaggcatatgaaaaaagtataaataat
gagaggacgctgaaaacacaggctgtgaacaaactggctgagataatgaatcggaaagac
ttcaaactcgacaaaaagaaggctagctctcaggatttaaggaaaaaagagagagagaac
agaaaactacagctcgatttgaaccaagaaaaagagaagtttaatcagatggtgtcgaag
tatcagaaggaactcaatgatatgcaagcgcaattagccgaagagagtttatgtaaaatg
gatcttcagatgcagctggatagcaaagagagtgatatagaacaactccgtgcaaaactg
tcagatctacaacttagaatggattctactagcgtttccagtctccaaacagatgaagct
gatggaattgttggagaatccagagttgaaggttggctttcaataccaaacaagggaaat
ataaaacgccatggttggaaaaagcagtatgttgtggttagcagtaaaaagattttattc
tataatgatgagcaggagaaagaacagtcaaatccgtctatggtacttgatatagataaa
cttttccatgtccgatcggtaacccaaggagatgtttacagagccgaaacagaagaaatc
cctcgtatatttcagattctttatgccaatgaaggtgaatgcagaaaagatgttgaaact
gaaccagcacagccagctgaaagaacaaattttctaaatcacaaaggtcatgagttcatt
cctacgctgtaccattttcctgccagctgtgaggcttgtaccaaacctctttggcatgtt
tttaaaccccctccagccctcgaatgtcgtcggtgtcacgttaagtgccataaagatcat
ttggacaagaaagaggaagtcattactccatgcaaagtgagctatgatgtgacttcagca
cgagatatgttgttgttggcgtgctctcaggacgaacagaagaaatgggtcacacatttg
gtaaagaaaattcctaaggccccacctacagaatttgtacgggcatctccaagaacagta
tctaagagatctactgcaaatcagtccttccgaaaagctgtcaaaaatgcatctggaaaa
gccagttaa
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