Pleurodeles waltl (Iberian ribbed newt): 138288306
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Entry
138288306 CDS
T10800
Symbol
LRRK2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
pwl Pleurodeles waltl (Iberian ribbed newt)
Brite
KEGG Orthology (KO) [BR:
pwl00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pwl01001
]
138288306 (LRRK2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pwl04131
]
138288306 (LRRK2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
pwl04147
]
138288306 (LRRK2)
Enzymes [BR:
pwl01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
138288306 (LRRK2)
Protein kinases [BR:
pwl01001
]
Serine/threonine kinases: TKL group
LRRK family
138288306 (LRRK2)
Membrane trafficking [BR:
pwl04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
138288306 (LRRK2)
Exosome [BR:
pwl04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
138288306 (LRRK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
LRR_8
Roc
COR
LRR_4
Ras
LRR_14
LRR_1
Ank_2
Arf
WD40_2
Beta-prop_RSE1_2nd
LRR_9
Beta-prop_EML_2
ABC_tran
TniB
Gtr1_RagA
T2SSE
GTP_EFTU
MMR_HSR1
DLIC
G-alpha
Septin
nSTAND3
WD40_like
AAA_7
Beta-prop_BBS7
Kdo
AAA_16
Beta-prop_HPS5
NACHT
PduV-EutP
SRPRB
AAA_29
AAA_22
TrwB_AAD_bind
ResIII
MobB
Motif
Other DBs
NCBI-GeneID:
138288306
NCBI-ProteinID:
XP_069085861
LinkDB
All DBs
Position
4_1:986832052..988278396
Genome browser
AA seq
2509 aa
AA seq
DB search
MEAARLEKLLERLRDLQERRPIDTQIQILDDLLVFTYFETAPELFKGKNVHAPLLLVLHS
YNKIAGVQQIGWSLLCRLIEVCPDTLEEIFPAQDVETDWEMLSFHQQILNVLSLHSANLN
LLTIVLKTLTLLLTSDSIVLLLLHEKEDVFQLLCDAMRTFPYDEDVQKYGCQALHFLFQK
VTEEDLMEFVESKDHLVILDSLKQFHKEEGVVLPAFYALLSLAGPSNNVEVLMSGNVRCY
NLIMESMKTFPDSENIQEVSCRLFQRLTLVNFLNILVSHEAYKVIAQAVLKYPENAPIQA
AGLICLALLVETIFLNRDLEEMEEQNEEEEEETNPLCWLDAACTALQFHRNNSAVQEAAC
LVLNSLFMYHRDLHEKIQHGDQTYQVHKEIMLTMLTHHTSKEVFQAAANAMATLLEHNAH
LVQVLLIRGIHMNVLEIMKIHSSSPDVAESACRLLSHLLADSSLNLDAMTMAASGIIHTM
KRHASISSVQLEALRAISHLTMADDEIKQLIDSRDSDNECWHLTLKVIKNQCLLEGIHTL
TLDALNKFLGYPAIQECGLRILCSVSECSGAGTLLSDQGAMDTVLHTLQMYPDNYGIQCQ
GLRLMELLINGKNLCISTVNLLAKLLVSVLQRFKDCIEIQKHGFETALTVIGLSQSFSKL
LEQESFTAVLFYQINMAFNGKRDPQFKALSCKCFAAMIYEENLRNKLFEKACTDGNIMVA
QCLLLLGADVNQKTNKDSLIYQVCEKGNNIRLVELLLNGGAREQDVREALNISIKKGNSE
VISLLLRKLALDLANNSICLGGFRIGNIEPSWLSPLFPRTSSALKHEPDQERKKDSGHLL
ARMVLRHQRKQEESLADGTAALSVMISPESADECSSIQDTSIETAFYGEDDAEVGSETST
PIRKHPHSVSIVDQHREPFKLDNSPFRRRSSNSLGPNAEYNPSVCRRKTSGRQILKHSDS
SSSLAVEREPIKALDLSENELETFSLVDQKASLMEHLEHLEKLELHQNSLESFPKKLCET
LKCLWHLDVHSNRFTLFPSHILEITHIKYLDISRNYIGPSLQLSPTLRCYALKYLNLSYN
NLTSIPECIGDVLEKLQDLILEGNKISNITSPLRLTELRTLNLTKNSISSLGNTIFEGCC
KLDMFSVMMNILDTVPSLPSKLTTLKLHENTFISIPKEILQLTHLRSIDLSNNKIVDLPG
PAHWASSNIRELVFSHNQIAVLNLKDDPSKWSKLEKLVLSHNKIKEIPPEIGFLENLTTF
DVSHNPELRRFPDEMGKLTKVWDLPLDGLNLDLDLNHLGYKAKDIISFLQQRLKKAVPYN
RMKLMIVGNTGSGKTTLVHQLMKCKHPDQGTKKATVGIDVKDWPVRSKQNTKKELTLNVW
DFAGEEEFYSAHPHFMTQRALYLVVYDLSKGSAEVDSIKPWLFNIKARASVSPVILVGTH
LDVSDEKCRKACQIKISKELFNQRGFPAIHDYHFVNASEESDSLKNLRKTIIAKSLQFKI
REQPVVGQLIPDSYLQLEKRILHERKLVASEFPVIDQKRLLELVQESQLHLDENEIPHAV
RFLNESGVLLHFEDPALQLRDLYFVDPQWLCKIMAQIFMVKQEGFSEYSKGVILRSTVEK
FLSREKIFPEDYMSQYFKLLEKFQIALPLRKDQLLIPSSLSDHRPAVELPHCENSEIIVR
LYEMPYFPMGFWSRLINRLLEISSYMLSGRERTLRPSKMYWRQGIYLSWSQEAYCLAEST
VLDNNADSFLKVTVPCGRKGCILLGQIVDHIDSLMEEWFPGLLETDVCGEGETLLKKWVL
YSFEDGQEHKQILLDDLLKVAEQGDLLVNPEDARSTIPIAQIAPDLVLADLPRNIMLNSD
VLDLVLSPEFLLGDGGFGTVYRASYRGENVAVKIFNKHTSPRLLRQELTVLSHLRHPSLV
SLLAAGIRPRMLVMELAPKGSLDRLLQQDITIFTRSTQHRIALHVADGLRYLHSAMIIYR
DLKPHNVLLFTLYPSSAVIAKIADYGIAQYCCRMGIKSSEGTPGFRAPEVAKGNVIYNQQ
ADVYSFGLLLYDILTNGCRIAEGLKFPNEFDELAIHGKLPDPVKEYNCDPWPEVENLIKH
CMKQNPEDRPTSAKVYELLNSPELICLMRFVQVPSTFTAECMVVDNVSCKKPIVWIDNGR
TDKGQLSRLDLNKGGHTCEDIADSRILCLAIVYLPSEQEHWILAGTQSGSLVVLNAEHIE
SKHCLQKMSDSITCLFCKTFSKQSKKKNFILVGTADGKIAIFEDVAIKCKDAAPIKIITV
GDVSTPIVGLCESTYSSERNAIWGGCGTKIICLSQEFVIQKHIDTMSTQASPQPLFADAN
IISLAVDEYIYVAKKTSYIVEVWDRKTDKRIELINCVHFLRDAGMKSKESKQEVDHLARV
KVLFLQKNTALWIGTGGGHLLLVDFSTSRPIRIITGFCDSIRCMVSTHLGKAKTKNVVLV
LGCRFTPQKEVQSFLFVWNANLPHEVHNLKKHIEMRQELTDKMKSFSLD
NT seq
7530 nt
NT seq
+upstream
nt +downstream
nt
atggaggcggcgcgtctcgagaagctgctcgagcgcctgagggacctgcaggagcggcgg
cccatagacacccagatccagatactggacgacctgctcgtctttacctactttgaaacc
gctcctgaacttttcaaaggaaaaaatgtccatgctccgttgcttctggttctgcattct
tacaacaaaattgctggagttcaacagattggttggtcacttctttgcagattaatagaa
gtttgccccgacactttggaggaaatttttcctgcgcaagatgttgaaacagattgggaa
atgctgagttttcatcagcagattcttaatgtgctgtccttgcatagtgcaaatctaaac
ctattgaccatcgtacttaagactttaactctgctcctaacatcagattccatagtgctg
ctgcttttgcatgaaaaggaggatgtttttcagttgttatgtgatgccatgcgaactttc
ccctatgatgaagatgtgcagaaatatggatgccaagctttgcactttctgtttcaaaaa
gtcacagaagaagatctgatggagtttgttgagagtaaagatcatttggtcattttggac
tcacttaagcagtttcataaagaggagggtgttgttctaccagcgttttatgctttgctt
tctttagctggtccatcgaacaacgttgaagtgcttatgtctggcaatgttagatgctat
aatttaataatggagtcaatgaaaacatttccagacagtgaaaatattcaagaagttagt
tgtcgtttgttccagagactaacgttggtaaactttttaaacatcctggtatcacatgaa
gcgtacaaagttattgcacaagcggttttaaagtacccagaaaatgctcccatacaagca
gcgggactcatctgtttagctcttcttgtggagacaatatttttaaaccgagacctagaa
gaaatggaagaacaaaatgaagaagaggaagaagaaacaaatccactttgctggttagat
gctgcctgcacagcattacaatttcatagaaataactccgctgttcaggaggctgcttgt
ttggtcctcaacagtttgtttatgtaccacagagatcttcatgaaaagattcaacatggt
gatcaaacgtatcaagtgcataaggaaataatgcttactatgcttacccaccacacatca
aaagaagtgtttcaagcagctgctaatgccatggcaacgttattagagcataatgctcat
ctcgtacaagtgctgctgataagagggatacacatgaatgtactggaaatcatgaagata
cattcaagctccccagatgtcgcagaaagtgcatgcaggctgctaagccatcttctagcg
gacagttctcttaatctggatgcgatgactatggctgcatcagggattatacataccatg
aagcgacatgcaagtatttcttctgtccagctggaggccctacgggccatttcacattta
acaatggctgatgatgaaataaaacagctgatagactccagagactctgataatgaatgt
tggcacctaacactgaaagtaataaagaaccaatgtttattggaaggaatccatacttta
acacttgatgcactaaacaagttccttggatatcctgccattcaggaatgtggattaaga
atactttgctctgtatctgagtgctctggagcaggaacactattgtctgaccagggtgct
atggacactgttctccatactttacagatgtatccagataattatggaattcaatgccaa
ggattaaggctgatggagttgttaattaacgggaagaatctgtgtatatcaactgtgaat
ctcctagcaaagttgttggtttcggttttacagcggtttaaggattgcatcgaaatacag
aagcatggatttgaaacagctttgaccgtgattggtttatcacagagcttttctaagctg
ctagaacaggagtcatttactgctgttctgttttatcagattaacatggcgtttaatgga
aaaagggatccacagtttaaagcattgagctgcaaatgttttgctgcgatgatatacgag
gaaaacttacggaacaagttgtttgagaaagcatgtactgatggcaatatcatggttgca
caatgtttgcttttgttaggagctgacgttaatcagaaaacaaataaagactcattaatc
tatcaggtatgtgaaaaaggaaacaacattagattggtggaactgctattaaatggagga
gctcgtgagcaagatgttcgagaggcattaaatattagtattaagaaaggcaacagtgaa
gtcatcagcttgcttttaagaaaacttgcccttgatctagctaataatagcatatgtctt
gggggctttcggattggaaacattgaaccttcttggttgagtcctttattccccagaaca
tcatctgctttaaaacatgaaccagaccaggaaaggaaaaaagattcaggccatctgctg
gcaaggatggtgctgcgacatcagaggaagcaagaagaatctctagctgatggaactgct
gccttaagtgtcatgatcagcccggaatctgctgatgagtgttcctccatacaggacact
tctatagaaactgccttttatggtgaagatgatgcagaagtaggaagtgaaacgtcaact
cctataagaaaacatccacattccgtttccattgttgatcagcatagagagccatttaag
ttggacaacagtcctttccgtcgaaggagttcaaattcgttgggacccaacgcagaatat
aatccttcagtgtgtagaagaaaaacgtctggcaggcaaatattaaaacactcagacagt
tcgtcttcattggccgtggaaagggagcccattaaagcactcgacctttcagaaaatgaa
ctggagacattcagtctggtagatcaaaaagcctccctcatggaacatttagaacatctt
gagaaactggagttgcatcaaaattcgcttgaaagttttccaaagaaactatgcgaaact
ttaaaatgcttgtggcatttggacgtgcacagtaaccggtttacattgtttcccagccac
attttggagatcactcatataaagtacctcgacatttctcgaaattatattggtccttct
ttacaattatctccaactctgagatgctacgctcttaaataccttaatctctcttacaac
aacttgacgagtattcctgaatgtattggggatgttttggaaaagcttcaggatcttatt
ttggaaggaaataaaatttctaacattacttcaccattacgcttgactgagctgagaacc
ctaaaccttactaagaacagcatttcttcactggggaatactatttttgaggggtgctgc
aaacttgatatgttcagtgtaatgatgaatatcctggatacagttcctagtttgccatct
aaattaacaactctgaaattgcatgagaatacatttattagtattcccaaggaaattctc
caactaactcacttacgatcaattgacttgagcaacaacaagattgtggacttacctggg
cctgcacactgggcatcttccaatataagagaacttgtattcagtcacaaccagattgct
gttttgaacttgaaagatgatccttccaaatggtcaaaattggaaaaactggtcctgtct
cataataagataaaagagatcccgcctgaaattggtttccttgaaaacctgaccaccttc
gatgttagtcacaatccggagctgaggcgttttcctgatgaaatgggaaaactcacaaaa
gtgtgggaccttccattggatggcctaaatttggatttggatctgaaccaccttggatac
aaagccaaagatattattagttttctacagcagcgcttaaagaaggctgttccgtataac
cgaatgaaacttatgattgtgggaaatactggaagtggcaaaactacactggtgcatcaa
cttatgaagtgcaagcatcccgaccagggtaccaaaaaggcaactgtaggcattgatgtg
aaggattggcctgtacgctccaagcaaaatacaaaaaaagaacttacattaaatgtgtgg
gatttcgcaggagaagaagagttctacagtgcgcatccccatttcatgactcagcgagca
ttgtacctggttgtgtatgacctcagtaaaggatccgcagaagtggattccattaagccc
tggctattcaatattaaggctcgagcttcagtgtctccagttatacttgttggtactcat
ttggatgtttctgatgagaaatgtcgtaaagcctgccagattaaaattagcaaagagctg
ttcaatcaacgtgggtttccagcgatacatgattaccattttgtaaatgcttctgaggag
tctgattctttgaaaaacttaagaaaaaccatcatagccaaaagtctgcaatttaagata
agggaacagccagtggtgggtcagttaatccctgatagttatctgcagctggagaagaga
attctgcatgaacggaagcttgtagcgtctgaattccctgtgatcgatcaaaaaaggtta
ttggaactcgtgcaagaaagtcagttacatttggatgaaaatgaaattcctcatgcagtt
cgttttctgaatgaatcaggtgtgcttctgcattttgaagatccagcattgcagctgaga
gatctgtattttgtggacccacagtggctctgtaaaatcatggcacagattttcatggta
aaacaggaaggcttttcagagtattcaaaaggagttattctgcgttccactgtggagaaa
tttctatcaagagagaaaatatttccagaggattatatgtcacagtattttaagcttctg
gaaaaattccagattgctttgcctttaaggaaagatcagctccttattccaagcagtcta
tccgatcacagacctgccgtagagcttccccactgtgaaaactcagaaataattgttaga
ctgtatgagatgccatactttccaatgggcttctggtctcgacttataaacagattgctt
gaaatatcttcgtacatgctctctggacgagagcgcacacttcgcccttcaaaaatgtac
tggagacaaggaatctacctgagttggagtcaggaagcctactgtttggcagaatctaca
gtcttggacaacaacgcagatagctttttgaaggtcacagtcccctgtggcagaaaaggt
tgtattttgttgggacaaatagtcgatcatattgactctcttatggaagaatggttccct
ggcctcttggaaactgatgtatgtggcgaaggtgaaacactgttgaaaaagtgggtttta
tacagcttcgaggacggtcaagaacataaacaaattttacttgatgatttgctaaaggtg
gctgaacaaggtgacctcttagttaatcctgaggatgcaaggtcaacaattccaattgct
cagattgccccagacttagttttggcagaccttccccgaaatatcatgttaaacagtgat
gtgctggaccttgttctttcaccggaattcttgttaggtgacgggggatttggcacagtt
tatcgtgcatcatatagaggagaaaacgtagctgttaagattttcaacaaacacacgtcg
ccaaggctcttaagacaggagctcactgtgttaagtcaccttcgccaccctagcttagtg
tctttattggctgctggtattcgtccaaggatgttagtaatggaactagccccaaaaggc
tccctagaccgtctacttcaacaagatattactatttttactagatctactcagcatcga
atagctctacatgttgcagatggactgagatatcttcattcagcaatgataatatacagg
gacttaaagccacacaatgtactactctttacactgtatcccagttctgccgtaattgca
aagattgctgattacggcattgctcagtattgctgtagaatgggaataaaatcttccgaa
ggcacaccaggatttcgtgcaccagaggttgcaaaaggaaatgtaatctataatcagcag
gctgatgtgtattcctttggtttgctcctgtatgacattttaacgaatggatgtcgtata
gctgaaggtttaaaattcccaaatgagtttgatgaattagctattcatggaaaattaccc
gatcctgtgaaggagtacaactgtgatccatggcctgaagttgaaaatttgataaaacac
tgtatgaagcaaaatccagaggataggcccacctctgcaaaggtgtatgaacttttaaac
tcaccagagctcatctgtttgatgagatttgtgcaagtgcctagtacctttacagcagag
tgtatggtggttgacaacgtgagctgcaaaaagccaatagtgtggattgataatggaagg
acagacaaaggacagctgtcacgccttgatctcaacaaaggtggacatacatgtgaggac
attgctgatagtaggatcctgtgtcttgccatagtttatcttccaagtgaacaagagcac
tggatattagcaggaacacaatcaggttctcttgtagttttgaatgcagaacacattgaa
tccaagcactgtcttcagaagatgtcagattccatcacatgtttgttctgcaagaccttt
tcaaagcagagcaaaaagaagaattttattctggttgggacagcagatggtaaaatagct
attttcgaagatgtagcaatcaagtgtaaagatgcagcgcctatcaagataataactgta
ggagatgtgagcacaccaatagtggggttatgtgaatcaacatactcttcagaaagaaat
gccatctggggaggatgtgggacaaagatcatatgtttgtcccaggagttcgtaattcaa
aaacacattgataccatgagcactcaagcatcgcctcagccattgtttgctgatgcaaat
attatttccttggcagtggatgaatacatatatgtggcaaagaagactagctatattgtg
gaagtctgggataggaagacagataaacgaattgagttaatcaactgtgttcattttctc
agggatgctggaatgaaaagcaaagagtcaaaacaagaggtggatcatttagcaagagtg
aaggtgctctttctgcaaaaaaatacagccctatggataggaacaggtggaggtcacctg
ctattagttgacttttcgaccagtcgccctatccgaataattactggtttttgtgattct
attcgatgcatggtttcaactcatttaggaaaagccaaaactaaaaatgttgtgctggtt
ttaggatgtcgatttacaccacagaaagaagtgcaatcctttctttttgtctggaatgct
aaccttccacatgaggtgcacaatttgaaaaaacatattgaaatgagacaggagctgaca
gataaaatgaaaagcttttctttggactaa
DBGET
integrated database retrieval system
