KEGG   Pleurodeles waltl (Iberian ribbed newt): 138295692
Entry
138295692         CDS       T10800                                 
Symbol
PLCB1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
pwl  Pleurodeles waltl (Iberian ribbed newt)
Pathway
pwl00562  Inositol phosphate metabolism
pwl01100  Metabolic pathways
pwl04020  Calcium signaling pathway
pwl04070  Phosphatidylinositol signaling system
pwl04081  Hormone signaling
pwl04082  Neuroactive ligand signaling
pwl04261  Adrenergic signaling in cardiomyocytes
pwl04270  Vascular smooth muscle contraction
pwl04310  Wnt signaling pathway
pwl04371  Apelin signaling pathway
pwl04540  Gap junction
pwl04621  NOD-like receptor signaling pathway
pwl04912  GnRH signaling pathway
pwl04916  Melanogenesis
Module
pwl_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:pwl00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    138295692 (PLCB1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    138295692 (PLCB1)
   04371 Apelin signaling pathway
    138295692 (PLCB1)
   04020 Calcium signaling pathway
    138295692 (PLCB1)
   04070 Phosphatidylinositol signaling system
    138295692 (PLCB1)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    138295692 (PLCB1)
   04081 Hormone signaling
    138295692 (PLCB1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    138295692 (PLCB1)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    138295692 (PLCB1)
  09152 Endocrine system
   04912 GnRH signaling pathway
    138295692 (PLCB1)
   04916 Melanogenesis
    138295692 (PLCB1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    138295692 (PLCB1)
   04270 Vascular smooth muscle contraction
    138295692 (PLCB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pwl04131]
    138295692 (PLCB1)
Enzymes [BR:pwl01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     138295692 (PLCB1)
Membrane trafficking [BR:pwl04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    138295692 (PLCB1)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    138295692 (PLCB1)
SSDB
Motif
Pfam: PI-PLC-X PLC-beta_C PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like HP1451_C
Other DBs
NCBI-GeneID: 138295692
NCBI-ProteinID: XP_069090246
LinkDB
Position
5:complement(387339507..389381727)
AA seq 1220 aa
MAGAQPGVHALQLKHVSVPENLKKGTKCMKWDDDSTVVSTIILKMDPQGFFLYWTDQNKE
TELLDISFVKDARCGKHARTPKDPKVREQLEVGNFGGRLESRMVTVVYGPDMVNISYLNL
LAFQEEIAKEWADEIFNLATNLLAQNMSRDACLEKAFTKLKLQVTPEGRIPVKNMYRLFS
ADRKRIETALESCNLPSGRSDSIPQDDFTPEAYRAFLNNICPRPEIDNIFTEFGAKSKPC
LTVDQMMEFINCKQRDPRLNEILYPFLKQEQVQQLIEKYEPNNDLAKKGQISVEGFMSYL
SGEENGVVPPEKLDVNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLAGCRC
VELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPYPILLSFENHVDSPK
QQAKMAEYCKMIFGDGLLTDPLEKYPLESGVPLPSPMDLQFKILVKNKKKSHKSSEGSSK
KKLSEQASNTFSDSSSVFEPSSPGAGEADIESEEEDDDDEDDCKKSFMDEGTAGNEASAT
EEMSNLVNYIQPVKFETFEMSKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRI
YPKGTRVDSSNYMPQVFWNAGCQMVALNFQTIDLAMQLNMGMYEYNGKCGYRLKPEFMRR
PDKQFDPFTESTVDGIVANTVSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKT
SQGNAINPVWEEEPIVFKKVVLPSLACLRIAVYEEGGKFIGHRILPVSAIRPGYHYICLR
NEKNIPLILPALFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRARQLAALTLEDEEE
LKKEIDQGEAPSEAHSEPRPAPAENGVNHTSSLTPKAPAQPVHSQPAPGSVNIPAKSEDL
IHSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTAKYNEIQN
DYLRRRAILEKSAKRDSKKRCETSSPDHSLATIEHDLTTLDTEMAQKLNELKEQQQQQLL
NLRQEQYYSEKYQKREHIKQLIQKLTDVAEECQNSQLKKLKETCEKEKKELKKKMDKKRQ
EKITETKSKDKNQMEEEKTEMIRSYIQEVVQYIKRLEDAQTKRQEKLLETHKEIRQQILD
EKPKLQVELDQEYQDKFKRLPMEIQEFVQEAMKGKFSDDGEHSSATSSLAPDSGKLNHKP
LSNEVEAEVDSAEKGFDTSL
NT seq 3663 nt   +upstreamnt  +downstreamnt
atggctggggctcagccaggtgtccacgcgttgcagctcaaacatgtcagcgtccctgag
aacctgaagaaaggcaccaagtgcatgaaatgggatgatgactccactgtcgtgtctaca
attattctcaaaatggacccccagggatttttcctgtactggacggatcagaataaggaa
acagaattgctcgatatcagcttcgttaaagatgccaggtgtggaaaacacgcaagaaca
ccaaaggatccaaaagtccgagaacaactggaagtaggaaacttcggaggtcgcctcgag
agccgcatggttactgtggtctatggtcctgatatggtcaacatctcctacctgaaccta
ctggcattccaggaagaaattgcaaaggaatgggcagatgagattttcaatctggcgaca
aacctgctggcgcagaacatgtcaagggatgcatgtctggaaaaagcttttaccaagctc
aagctgcaagtcactcctgaaggacgtattccagtaaaaaacatgtatcgtttattctca
gcagacaggaagcggatagaaaccgcactcgagtcatgcaatcttccatctggcaggagc
gattcaatcccacaagatgacttcacgccagaagcatacagagcgtttctaaacaacata
tgccctcgaccagaaattgacaacatctttaccgaatttggtgccaaaagtaaaccatgc
cttaccgttgaccagatgatggaatttattaattgcaaacaacgagacccacggttaaat
gaaattctgtatccctttctgaaacaggagcaagttcaacagcttattgaaaaatatgag
cccaataatgatctagcaaaaaaagggcaaatatcagtggaaggatttatgagctacttg
agcggagaagaaaacggagttgtcccccctgagaaactggatgtgaacgaagacatgtct
cagccactgtctcattatttcataaattcctcacacaatacctacctcacagctggacag
ctggctggcaactcctcggttgagatgtatcgccaagtgctgctagcaggctgtcgctgt
gtcgagctggactgctggaaggggagaacagccgaagaagagccagtcattacacacggg
ttcaccatgacaactgaaatctccttcaaggaagttatagaagctattgccgaatgtgca
tttaagacatcgccatatccaatcctcctctcctttgaaaaccatgtagactcaccaaag
cagcaagccaagatggcggagtattgcaaaatgattttcggggatgggttgcttaccgac
ccgctggaaaaatatccgctcgaatctggagttccgctgccaagtcccatggacttacag
tttaaaatccttgtgaaaaacaagaagaaatcacataagtcttcagaggggagttctaag
aaaaagctatccgagcaggcatccaacaccttcagtgactcgtctagtgtgtttgagcct
tcctctcctggagcaggtgaagctgatatagaaagtgaagaagaagatgatgacgatgaa
gatgactgtaaaaaatctttcatggatgagggaacagcaggaaatgaagctagcgccact
gaagaaatgtcaaacttggttaattacattcaaccagtgaagtttgaaacttttgagatg
tctaaaaagcgtaacaagagttttgaaatgtcttcctttgtggaaaccaaaggccttgag
caacttactaaatctccagtagaatttgtggaatataacaaaatgcagcttagccggatc
tatccaaagggaacgcgtgttgattcttcaaattatatgcctcaagttttctggaatgct
ggttgtcagatggttgcacttaacttccaaacaatagatttagccatgcaattgaatatg
ggaatgtatgaatacaatggcaaatgtggataccggctaaagccagagttcatgagaaga
ccagacaaacagtttgaccctttcacagaaagtactgtagatggaattgtggcaaacaca
gtgtctgtaaagataatttcaggccagtttctttctgataagaaagttggcacttatgta
gaagtagacatgtttggcttgcctgtggacacacgacggaaagctttcaagacaaagact
tcccaaggcaatgcaatcaaccctgtgtgggaagaagagcctatcgtgtttaagaaggtt
gtgctaccttcattagcatgtctacggatagcggtatatgaagaaggaggaaaatttata
ggtcaccggatattgcccgtctcagcgatccgaccagggtaccactacatttgcttaagg
aatgagaagaatatccccttgatactgcctgcacttttcgtctatatcgaagttaaagat
tatgtcccagacacttatgccgatgtcattgaagcactctccaatccaatcagatacgtc
aacctgatggaacaaagagcacggcagctggcagcattaacgttagaagatgaggaagag
ctaaagaaagagattgaccaaggcgaagcaccatcggaggcccacagtgaacccagacct
gcgcctgcagaaaacggagtcaaccacacttcatcgctgacccctaaagcacctgcacag
cccgttcacagccagccggccccaggttcggtaaatattcctgcaaagtcagaagatctc
attcacagtgtcctgacagaggtagaagcccagacaatagaggagctcaaacaacagaag
tcgtttgtcaaacttcaaaagaaacactataaagagatgaaggacctcgtcaagagacac
cacaagaaaaccacagatcttattaaagaacacactgccaagtacaatgaaattcagaac
gattacctgagacgaagggcgatcctagaaaagtctgccaaacgagacagcaagaaaagg
tgtgaaacaagcagccccgatcacagcttagcaacgattgaacacgacttaaccacattg
gacactgaaatggcacagaagttaaatgagctcaaagagcagcagcagcagcagttgtta
aatctccggcaagaacagtattatagtgaaaagtatcaaaagagagaacacattaagcag
cttattcaaaaactgacagatgtcgccgaagagtgtcagaacagccagctgaaaaagcta
aaagaaacctgtgaaaaagaaaaaaaagagctgaagaagaaaatggataagaagaggcaa
gagaagatcacggaaacgaagtcaaaggataaaaaccaaatggaggaggagaagacagaa
atgattcgatcgtacatccaggaggtggtacagtacataaaacggttagaagacgcgcag
actaaacggcaagaaaagcttttagaaacacacaaggaaattcgccagcagatattggat
gaaaaacctaagttacaggtggaactcgatcaagaatatcaagacaagttcaagaggctg
cccatggaaattcaagagtttgtgcaagaggcaatgaaagggaagttcagcgacgacggg
gagcacagctctgccacctcttctttggcgcctgatagcggcaaattgaaccacaaacct
ctctccaatgaggttgaagcagaagtagatagtgcagagaaaggatttgacacttcgctt
taa

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