Pleurodeles waltl (Iberian ribbed newt): 138295989
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Entry
138295989 CDS
T10800
Symbol
SRD5A2
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2
KO
K12344
3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:
1.3.1.22
]
Organism
pwl Pleurodeles waltl (Iberian ribbed newt)
Pathway
pwl00140
Steroid hormone biosynthesis
pwl01100
Metabolic pathways
Module
pwl_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
Enzymes [BR:
pwl01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
138295989 (SRD5A2)
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NCBI-GeneID:
138295989
NCBI-ProteinID:
XP_069090785
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Position
5:723847820..724454275
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AA seq
254 aa
AA seq
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MQCTRDLDLYMSSALGLLGVLLLVRQKFTPATYGKHVDVLNKHTYIMVPAKCGWFLQELP
SFLVPFLLVIYSPQPGSPGCWLLLLTFCWHYFHRTFIYSLFTRGRPAPLQIVIMAVIFCS
YNGFLQGHCMVYNAKYSDGWYMDMRFLSGMLVFSTGMAINIHSDHILRNLRQPGEETYKI
PQGGFFNYVSGANFFGEIVEWFGYAIATWTLPAFSFAFFTLCSIGPRAYHHHKFYLKKFA
DYPKSRKALIPFIF
NT seq
765 nt
NT seq
+upstream
nt +downstream
nt
atgcagtgcacacgggacctggatttgtacatgagctcggcgctgggtctgctaggcgtc
ctattgctggtccgccagaagttcaccccagccacttacggcaagcacgtggacgtgctc
aacaagcacacgtacataatggtgcccgccaagtgcggctggttcctgcaggagctgccc
tccttcctagtgcccttcctgctggtgatctacagtccccaacccggctcccccggttgc
tggctgctgctcctcaccttctgctggcactacttccacaggacatttatatattcattg
ttcacaagaggacgacctgcgcccctccagatagttatcatggctgtgatcttctgttcc
tacaacggctttcttcaaggtcactgtatggtttataatgctaaatattcagatggctgg
tacatggacatgagatttttgtcaggaatgctcgtattctcaactggcatggcgatcaac
attcacagcgatcacattcttcggaatttaagacaacctggagaggaaacctataaaata
ccacaaggaggctttttcaactacgtgtctggtgcaaacttctttggtgagattgtggaa
tggtttggctacgccatagcaacttggaccttgccagcattttcgtttgcattctttact
ctgtgctcaattgggccacgagcttatcaccatcacaagttttatctcaagaagtttgca
gactaccccaaatcaagaaaagccttaatcccgttcattttttaa
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