KEGG   Pleurodeles waltl (Iberian ribbed newt): 138299279
Entry
138299279         CDS       T10800                                 
Symbol
ERBB2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2
  KO
K05083  receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
Organism
pwl  Pleurodeles waltl (Iberian ribbed newt)
Pathway
pwl04010  MAPK signaling pathway
pwl04012  ErbB signaling pathway
pwl04020  Calcium signaling pathway
pwl04510  Focal adhesion
pwl04520  Adherens junction
pwl04530  Tight junction
Brite
KEGG Orthology (KO) [BR:pwl00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    138299279 (ERBB2)
   04012 ErbB signaling pathway
    138299279 (ERBB2)
   04020 Calcium signaling pathway
    138299279 (ERBB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    138299279 (ERBB2)
   04520 Adherens junction
    138299279 (ERBB2)
   04530 Tight junction
    138299279 (ERBB2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pwl01001]
    138299279 (ERBB2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:pwl04147]
    138299279 (ERBB2)
   04090 CD molecules [BR:pwl04090]
    138299279 (ERBB2)
Enzymes [BR:pwl01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     138299279 (ERBB2)
Protein kinases [BR:pwl01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   138299279 (ERBB2)
Exosome [BR:pwl04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   138299279 (ERBB2)
CD molecules [BR:pwl04090]
 Proteins
  138299279 (ERBB2)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 ABC1 Haspin_kinase RIFIN Kinase-like Adeno_E3_CR2 GAPT
Other DBs
NCBI-GeneID: 138299279
NCBI-ProteinID: XP_069093538
LinkDB
Position
6:complement(98797291..99043262)
AA seq 1255 aa
MARHGPLHCYIWGLLALLRGCSGSSGVCTGTDMKLLVPSSLQDHHQALRMLYTDCQVVQG
NLELTYLQAHDDLSFLKDIIEVHGYVLIAHTLVSFLPLENLRIIRGTQLYDDRFALAVLN
NSDGTAGLRELRMRSLTEILKGGVWITGNSQLCFQETLRWDDIFNKYNSIKETVLPVNRS
RDCGSCSPACASLPLGAPEACWGDEKKYCQILTQTICASGCARCKGKSSTHCCHEQCAAG
CTGPKNSDCLACLYFNDSGVCTQYCPPLRTYHPEIFESVYNENGRYTFGASCVTECPYNY
LSTEVGSCTLLCPHNTQEVTQNGIQKCEKCSTSCPKVCYGLGMDFLKGVSAVNSDNIKHF
SGCTKIFGSLAFVQDSFLGGGLDPEQLNVFRDLQEITGYLNIESWPETLSNLSVFENLKV
IRGRTLHRGAYSLAVHGLSITSLGLRSLMEISSGLVLIHQNPRLCFMDTIPWASILKNPH
QGLLQSNNKAVEECEHDGLVCFYLCAHGQCWGPGPTQCVMCDRFLRGQECVESCNILDGD
KREHVNGSRCLLCHLECQHQNGTQSCLGSGADQCISCAHYKDGSDCVETCPSGIKGDTYV
PFWKYPDEDGICQLCPTNCTHSCTVLDELGCPVDQKPSEINSIVAYVVGVLLLLVLILLG
VICFRRKNQLKRKHTLLRLLQENELVEPLSPSGAVPNQAQMKILKETELKKTKILGSGAF
GTVYQGIWIPDGENVKIQVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVCRLLGICLT
STVQLVTQLMPFGCLLEYVRENKDQIGSQDLLTWCVQIAKGMNYLEDVRLVHRDLAARNV
LVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVT
VWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPVCTIDVYMIMVKCWMIDSECRPRFRE
LVMEFSRMARDPSRFIVIQDDVNMGLTGPVDSRFYRTLLEDEMIQDIVDTDEYLVSHEGF
CNPETATNYRSRMPSAKSATDAPPADQGLTAESPECPYLGLALSQTSEGAGSDVFADGDY
VTSPTALLGPPLPRENSTLQRYSKDPTSPFSDETDGLETDGAPSLPSRNQSPEYVNQHEA
VALFPGRYQKPSVSTLEKQKGLLGKNGLVREPRDIVPLGFSSAMDNPEYLIPHSRPMPSP
QAQAFDNLYYWDQEPVTKGNRDDGAAANGFTTPTAENPEYLGLAESLSFPNDVST
NT seq 3768 nt   +upstreamnt  +downstreamnt
atggcccggcacggccccctgcactgctacatctgggggctgctggccctgctgcggggc
tgctccggcagctcaggagtatgtacaggcacagacatgaagctcctcgtcccttccagc
ctccaagaccaccaccaagcactacgcatgctctacaccgactgtcaagtcgtgcaaggc
aacctagagctgacttacttgcaggcacacgatgacctgtccttcctcaaggacattata
gaggtgcacggttatgtgctcattgcccataccctggtcagcttcctgccgctggaaaac
ctgcgcatcatccgaggcacccagctgtacgacgatcggttcgccctggctgtgctcaac
aactctgatgggacagcggggctgcgggagctgcgcatgcgcagtcttacggaaatcctg
aaaggaggtgtgtggattacgggtaattcgcagctgtgcttccaagaaactctgcgctgg
gatgacatcttcaacaagtacaacagcatcaaagaaactgtcctgcccgtcaacaggagc
cgtgactgtggatcttgttcccctgcatgtgccagtctaccgcttggggctccagaagcc
tgctggggtgatgaaaagaaatactgtcagatcttgacccagaccatctgtgccagcgga
tgtgcgaggtgcaagggcaagtcatccacgcactgctgccacgaacagtgcgccgctggc
tgcacggggcccaagaactcggactgtttggcttgtctgtacttcaacgacagcggcgtt
tgtacgcagtactgcccacccctgaggacctaccatccagaaatctttgaatctgtgtac
aacgagaatggcagatacacctttggtgccagctgtgtcactgagtgcccgtataattac
ctgtccacggaggtggggtcttgcacactcctgtgccctcacaacacccaggaggtgacg
cagaacggaatccagaaatgcgaaaagtgcagcacgtcctgcccaaaagtctgttacggg
cttggaatggactttctaaagggggtctcagctgtgaattcagacaatatcaaacatttt
agtggctgcacaaagatctttgggagtctggctttcgtgcaagacagtttccttggtgga
ggcctggacccggagcagctgaacgtttttagggaccttcaggaaatcacaggctattta
aacattgagtcctggccggagactttgtccaacctcagtgtgtttgagaacctgaaagtg
atccgtgggagaaccctacacaggggagcctattccttggcagtccacggtctctctatc
acttccctgggcctgcgctcactaatggagatcagcagcggcctggtgctgatccaccag
aacccccgactctgcttcatggacaccatcccctgggcctccatcctaaaaaatccgcac
caagggctactgcaatccaacaacaaggctgtggaagagtgtgagcatgatgggctggtc
tgcttctacctctgtgcccatggacagtgctgggggccaggccccacccagtgtgtcatg
tgcgaccggttcttgcggggccaggagtgtgtggaatcctgtaacatcctggatggagac
aagcgggagcatgtgaatgggagccgatgccttctctgccacctggaatgtcagcaccaa
aatggaacgcaatcctgccttggttcgggcgctgatcagtgcatttcttgtgctcactat
aaagatgggtctgactgcgtggagacctgtcctagtggaatcaaaggagacacatacgtg
cccttctggaagtaccccgatgaagacggcatttgtcagctttgccctacaaattgcaca
cactcgtgcacagttctggatgagttaggctgtcctgtggatcaaaaacccagtgagatc
aactccattgtagcctatgtggttggggtcctcctgctgcttgttctcatcctccttgga
gtcatctgcttcaggcggaagaatcaactaaagcggaagcacaccttgctgcgtctcctt
caggaaaatgagctggtggagccactaagtccaagtggggctgttccaaatcaggcacag
atgaagatcttgaaggagacagagctcaagaaaactaagattcttggatccggagctttt
ggcactgtctaccagggtatttggattccagatggagaaaatgtgaagattcaggtggcc
atcaaagtgttgcgagagaacacctctccaaaagccaacaaggaaattttagatgaagcc
tatgtgatggctggggtgggcagcccttatgtctgccgtcttttgggaatctgtcttact
tccactgtgcaactagtgacccagctgatgccgttcggctgcctgttggagtacgttcgt
gagaacaaggaccagataggctcacaggacctgctcacctggtgcgtgcagattgccaag
gggatgaattatcttgaggacgtgaggctagtacatcgagacttggctgcacggaatgta
ctggtcaagagtccaaatcacgtcaaaatcacagactttggactagctcggctgctggac
attgatgaaacagaataccatgctgatgggggcaaggttcccattaagtggatggccctg
gagtccattctccgtagaaggttcactcatcaaagtgatgtctggagctatggtgtgaca
gtttgggaactaatgacctttggagcaaagccttacgatggcatcccggctcgagaaatc
ccagacctactggagaagggggagagactgccgcagccccccgtctgcaccatcgacgtt
tacatgatcatggtgaaatgttggatgatagattccgaatgtcgacctaggtttcgcgag
ctggtgatggaattttctcgcatggcacgagacccctcgcgcttcattgtcatccaggat
gacgttaatatgggattgaccggtccggtggacagcaggttctatcgcacactcctggag
gacgagatgatacaagacattgtggacactgatgagtacctggtgtcacacgagggattc
tgcaaccctgaaacggctacaaactaccgcagtaggatgccctctgcaaagagtgctacc
gacgctcccccagcagaccaagggctgactgcagagtctcctgagtgcccgtatctgggc
ctggctctgtcgcagacctctgaaggtgcaggttcagatgtatttgctgatggagattac
gtgacgagtccaactgccctgctggggccccctctaccacgagagaacagcaccctgcag
aggtacagcaaggaccctaccagccctttcagcgatgagactgatgggctggaaactgat
ggggctccttccctgccatctcgtaaccagtctccagaatatgtgaaccagcatgaagca
gtggcactgtttccaggtcgatatcaaaaaccctctgtgtcaaccctggagaagcagaag
ggactgcttggtaaaaatggccttgttagggagcccagggatatcgttcctttgggattc
agcagtgctatggacaaccctgagtacctgatcccacatagccgacccatgccgagcccc
caggcacaggcgtttgacaacctatactattgggaccaggaacctgtcaccaagggcaat
cgagatgatggtgccgccgccaatgggttcaccacacccacagcagagaatccagagtac
cttggactggctgagtccctcagctttccaaatgatgtctctacttaa

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