Pleurodeles waltl (Iberian ribbed newt): 138300757
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Entry
138300757 CDS
T10800
Symbol
SIRT1
Name
(RefSeq) NAD-dependent protein deacetylase sirtuin-1
KO
K11411
NAD-dependent protein deacetylase sirtuin 1 [EC:
2.3.1.286
]
Organism
pwl Pleurodeles waltl (Iberian ribbed newt)
Pathway
pwl00760
Nicotinate and nicotinamide metabolism
pwl01100
Metabolic pathways
pwl04068
FoxO signaling pathway
pwl04148
Efferocytosis
pwl04218
Cellular senescence
pwl04310
Wnt signaling pathway
Brite
KEGG Orthology (KO) [BR:
pwl00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
138300757 (SIRT1)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
138300757 (SIRT1)
04068 FoxO signaling pathway
138300757 (SIRT1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
138300757 (SIRT1)
09143 Cell growth and death
04218 Cellular senescence
138300757 (SIRT1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
pwl03036
]
138300757 (SIRT1)
03029 Mitochondrial biogenesis [BR:
pwl03029
]
138300757 (SIRT1)
Enzymes [BR:
pwl01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.286 protein acetyllysine N-acetyltransferase
138300757 (SIRT1)
Chromosome and associated proteins [BR:
pwl03036
]
Eukaryotic type
Histone modification proteins
HDACs (histone deacetylases)
SIRTs (sirtuins, class III HDACs)
138300757 (SIRT1)
Mitochondrial biogenesis [BR:
pwl03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
138300757 (SIRT1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SIR2
TPP_enzyme_M
DUF592
Motif
Other DBs
NCBI-GeneID:
138300757
NCBI-ProteinID:
XP_069096614
LinkDB
All DBs
Position
6:1205990136..1206487005
Genome browser
AA seq
685 aa
AA seq
DB search
MTVFKSLSGSLFSCGDWWLQMADEQHGLHQQRSPDKGLRGSGEPAAKRSRADLVHRSAEE
SAGAIGACLSRRLQEREFLERDTSATHRNDPSSEAGQAPELRGNGFPPCDSDEDDRISHA
SSSDWTPRPRIGPYTFVQQHLLLGTDPRTILNNLLPETIPPPDLDDMTLWQIVINLLSEP
PKRKRRKDINTIADVVKLLEECKRILVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLP
DPQAMFDIDYFKRDPRPFFKFAKEIYPGQFQPSLCHKFIAMLDKDGKLLRNYTQNIDTLE
QVAGIQRVIQCHGSFASASCLICRYKVDSEAVRGDIFNQVVPRCPRCLPNEPLAIMKPDI
VFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPQEVPQILINREPLSH
LHFDVELLGDCDVIINELCQRLGKGYAKLGHNLVKLSETTEKPPQSQSDLEMQCTDVPLK
SVKTYEESNLHEKAAVPGPSLAVPTSEDVPYKPSHFEFLPKSELSCVEENVQELRVHIST
NSFIIDNNEPLVKIECLKEARSNEHNKIRDERNFEVETQQNNWHKRSNKKEPISKRLAST
QYLYLTPNRYIFHGAEVYSDSDDVISSSSCGSSDESGSSPSFDECTENDSDNDECYNAAA
NETSISAEVIQNCMADNDIKRTMSN
NT seq
2058 nt
NT seq
+upstream
nt +downstream
nt
atgaccgtgtttaaatctctctctggttcgctatttagttgtggggactggtggctgcaa
atggcggatgagcagcacggcctccaccagcaacgcagccccgataagggcctcaggggc
agcggggagcctgcggccaagaggtcccgagcagatctggtccataggagtgctgaggag
tctgctggagctataggtgcgtgtttgtcacgccggctgcaggagagggagttccttgag
agagatacgtccgccacccatcgcaacgatccttcgtcggaggccggccaggctcctgag
cttagaggcaatggttttcctccttgtgatagtgatgaagatgaccgtatttcacatgca
agttcaagtgattggactccacgacctcggataggtccttatacatttgttcaacaacat
ctgctgctgggcactgatcctcgaacaattcttaataatttattgcctgaaaccataccg
cccccagatttggatgatatgaccctgtggcaaattgttataaatctactttcagaacca
ccaaaaagaaaaaggcgtaaggatattaatactattgcagatgttgtgaagctgttggaa
gagtgcaaaagaattctcgtcttgactggagcaggggtgtctgtttcctgtggcatacct
gacttcagatctagagatggtatttatgctcgccttgcagtagactttcccgaccttccg
gatcctcaagcaatgtttgatatagattacttcaaaagggatccaaggccatttttcaag
tttgctaaggagatatatcctggccagttccaaccatcgctatgtcacaagttcatagcc
atgttggataaggatggaaaactacttaggaactacacccagaatattgatacattggaa
caagttgcaggaatccaaagagtaatccaatgtcatggttcttttgcatcggcttcttgt
ttaatatgcagatacaaggttgacagtgaggcagtcagaggagatatttttaaccaggtt
gtaccacgttgtccaaggtgtctacctaatgaaccacttgccattatgaaaccagacata
gttttctttggtgaaaatctgcctgaacagtttcacagagctatgaagtatgacaaagat
gaagtagatcttctgatcgtcattggatcatctttgaaagtaagaccagtagcacttatc
ccaagttccatcccacaggaagtgcctcagatcttaattaatagagaacctttaagccat
ctgcactttgatgtagaacttctgggagattgtgatgttattattaatgagttgtgtcaa
agactagggaaaggctatgcaaagcttggtcacaatctagttaaactctcggagaccaca
gaaaaaccgccacaaagccaatcggatcttgaaatgcagtgtacggatgtaccacttaaa
tctgtcaaaacgtatgaggagtcgaatttgcatgaaaaagcagccgtgcccggtccatca
cttgctgtcccaacttcagaagatgttccttacaagccatcacattttgaatttttaccc
aagtctgagctaagttgtgtcgaggaaaatgttcaggaactaagagttcacattagtacg
aactcatttattattgataataatgaaccgttggtgaagattgaatgcttaaaggaagct
agatctaatgagcacaacaaaataagagatgaaaggaatttcgaagttgaaacgcagcaa
aacaattggcataaaagaagtaataagaaggagcccataagcaaacgtcttgctagtaca
cagtacttatatcttactccaaatcggtacatttttcatggtgctgaagtttattcagac
tccgatgatgtcatatcgtcaagttcttgtggaagtagtgacgaaagtggatcctcccct
agttttgacgaatgtacagaaaatgatagtgataatgacgaatgctacaatgctgcggct
aatgaaaccagtatttcagctgaagtaatccaaaattgcatggcagacaacgatattaaa
agaacgatgagcaattga
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