Polynucleobacter wuianus: A8O14_00895
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Entry
A8O14_00895 CDS
T09802
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
pwu
Polynucleobacter wuianus
Pathway
pwu00300
Lysine biosynthesis
pwu00550
Peptidoglycan biosynthesis
pwu01100
Metabolic pathways
pwu01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
pwu00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
A8O14_00895
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
A8O14_00895
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
A8O14_00895
Enzymes [BR:
pwu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
A8O14_00895
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Hera_DD
Motif
Other DBs
NCBI-ProteinID:
ANI98776
UniProt:
A0A191UD16
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Position
160083..161525
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AA seq
480 aa
AA seq
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MSMMTLAQAHAMLPGSRLLNVSAEAAKIIALSRVGTDSRQIDTGELFVALAGERFDAHDF
LADVARSGAGAALVSNAEQCPTNLPGICVADTRIGLGNLAKAWRANYEIPLVLVTGSNGK
TTVKEMIAAIFKAAVGEAHTLVTKGNLNNDIGLPLTLLKLRSTDRLAVVELGMNHPGETA
QLAAIAQANIALINNAQREHQEFMATVAAVAEEHADVVRTLPKNGIAVFPADSEFTSVWR
EAAGARRVIDFALISTQINQTASVKGRLLSNGRVEVVAENGSVEIQLNTLGSHNVRNALA
ASAVAIAAGIGLEIIKEGLESFTPVNGRMQAKKIDPNHTLIDDSYNANPDSVRAAIDALK
QSGNISWLILGDMGEVGNQGPEFHREVGAYAAEQGVAKLFALGEQCQFAIKGFEGVAKNT
TASKAIHFSDMDSLIAQLRDALHAQSTGSNQHLNILVKGSRFMRMERVVQALLEEAKTCS
NT seq
1443 nt
NT seq
+upstream
nt +downstream
nt
atgtcgatgatgactcttgctcaagcacatgccatgctacctggaagtaggctattaaat
gtttctgctgaagcagcaaaaataatagcgctatcaagagtgggaaccgatagtcgccaa
attgatacaggcgaattattcgttgctttggctggtgagcgttttgatgcccatgacttc
ttggccgatgtcgcaagatctggggctggtgctgcattagtcagcaatgctgaacagtgc
ccaacaaatttgcccggtatttgtgttgccgatacacgcatcggcttgggcaatctggcg
aaagcctggcgtgcaaattatgaaattcctttggtgttggttaccggaagtaatggcaaa
accaccgttaaagaaatgattgctgcaatttttaaggctgcagttggagaagctcatact
ctggttaccaaaggtaatctcaataatgacattggcttgccactgactttattaaaactg
cgctctactgatcgtctagcagtagttgagttgggtatgaatcatcccggagaaacagcg
caattggctgcgattgcgcaagctaatattgcccttattaacaatgcccaacgcgagcat
caagaatttatggcaacggttgctgccgttgctgaagaacacgccgatgtagttcgtacc
ttgcccaagaatggcattgctgtattccctgcagattctgagtttacttctgtatggcgt
gaggctgctggtgcacgaagggtgattgacttcgctttgatctcaactcagataaaccaa
actgcttcagttaaaggtcgtctattaagcaatggacgggtagaagtagttgcggagaat
ggctcagttgagattcagctcaatacccttggaagtcacaatgtacgtaatgccctggct
gctagcgctgttgctatagcggcaggcatcggcctagaaataatcaaagaaggtcttgag
tcatttactcccgtaaatggacgcatgcaagcgaagaagattgaccctaatcacacatta
attgacgatagctataacgcgaatccagattcggtacgagctgcaattgatgcgcttaag
caatctggaaatatttcttggttgattttgggagacatgggagaggttggcaatcaaggt
cctgagtttcaccgtgaagtaggcgcgtatgcagctgagcagggggttgctaaattattt
gctcttggcgagcaatgccaatttgcgatcaaaggctttgagggggttgcaaaaaatact
acagcatccaaagcaattcacttttccgatatggacagtttgattgcacagttacgagat
gcattacatgcgcagtcaaccggcagtaatcaacatctcaatattttggttaagggttca
cgatttatgcgcatggagcgtgtagtgcaagccttgttagaggaggctaaaacatgctct
taa
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