Plutella xylostella (diamondback moth): 105386572 Help Entry 105386572         CDS       T03915                                  Name (RefSeq) protein purity of essence   KO K10691   E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27] Organism pxy  Plutella xylostella (diamondback moth) Brite KEGG Orthology (KO) [BR:pxy00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:pxy04121]     105386572 Enzymes [BR:pxy01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      105386572 Ubiquitin system [BR:pxy04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    UBR box proteins     105386572 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  E3_UbLigase_R4 E3_UBR4_N zf-UBR Motif Other DBs NCBI-GeneID:  105386572 NCBI-ProteinID:  XP_011555468 LinkDB All DBs Position Un AA seq 4027 aa AA seqDB search MQQGLSAVWVALGGRCLAWLGALLADARLEALSSGTPVATPTPAPPIIFAQYTAHQRARR LAAAAPLHQLLVALAVVSYRKATALKRAVVQKQHDADPDRSDSTVYFHDMILCSEDSETD DDSEPLFGLWFESTLVAPDAAESGGGGATEPDAAPAQPALVPDKAEPYSYIALATEIFTL LTAEIISPGAERLGASALQLHDSHVALLAALAKDLDRETARTDTGTISSCFGPRLGALYS QFSSALVRYLHNLSGAPGFASLLPALQQQLLTVPADSAANKTPLQVGPRVVKLLGSMVLS KPAAERENCILSMWHKLVHTLQECALQPQPAQDHDYEDLNVEHAQLLVYLFHSLTLMQKK SVLLMTSNAIIKVVETLSMSDRKRAANVLPHQLMLTTRLMLILEYLMRHLYDAPQSLLQQ IEWNLVIAPGLAQPSPEASAGAAGSTKPTTEGGQLAARIYCSVPHVEAAYRRLTQDESSM RPRFYALTTAEINNQENPKFDGLACNFVLGTPHKLKYPLLLDALLALLNSTCVCDNPAQA SSPAALTAAHYCFQTAWRLVVSMPPATPHMDKLAAGTAADLPAPLPLHALIWAPRADNKK VFNPWLKDALVKQGMYTQYAENLLAGVSASCDNIKYSAWLASKIIKHLKENITASGLPAL LDVISCDAALVRLHICLADAASAAEAHQFMPDLLELLATLVDCCRISAGMELECLTETGA SESVAAVNATRLLVCGTLCPIGPGAGPSPPPALGAWLRAQMPANASQALDRLSAPPPIQS RNTAIYANDIIPSESAVLNLVSSHCEIMSCGGVYSAWASLRMLGYSAAKLLEAGAGKLAE EPALAAAAGDLVVPALTDGRLEFMSEPLSCTLTTLVPQQLKAEQLIHEHILRTTYPMLVE HLQPATEKTLRHMVKYWEKILDRPAGRLAYEVVFAEGSEYSLGKILLSAPNARNPYAERV IKLFIKIFAGCESSELSSALCISVCKFLGVADKEKVASLLSHICFGGPAAPPSAGTANAS PVETELATPTTAAPEPNPASLALRNALRSVFRTEPTDTPSPAPRIQSDTAQPSTNSDTGS WSDAKPEAAAVPDAPAVPLSDATNDNALLLTHLCKHITMHCTEEVSERCLALLISVCGDT APAPLLLKEMCRLADAHNGQGHKQLFQACVNQLNVCVEQLSSQEVLEKLESGAADAGVAP QLESCGALLAYLADALHATSSAQPHTWRSVSPTWESPSDLGFDFECTDEQQDDDDTSADD SDEDAMLQYKLCTFTVTQREFMNQHWYHCHTCKMVDGVGVCSVCARVCHKSHDVSYAKFG NFFCDCGAKTDSSCQALVKRSATAGAGRGGSSDEPPPAPSLRRRPSSPAPSALPAPPRRP ALIHFIQGSRQYLSSYPEWTAVTEKIGRLLSALCGPVRAACERGAAVGAHGRAQRALAQL HLGDKHITSTDNLMLPTLGVTSPGSQEGAFENVRMSYTGENGQTIRQLMSSHKLRRVAMC CLASPQGRRQHLAVSHEKGKITVLQLSALLKQADSSKHKLTLTRLSSAPIPFTVISLSGN AANEDLLAVCGLKECHVLTFNSGGAVSDHLVINADVEATNYIIKAIWLPGSQTQLALVTS AFVKIFDLSTDLNNPMHYFLVPSGKIRDVTFVNQEGEQQMLCMSSAGHIYWQPMSEESRA TLGTFYVTNTLEVLHPEIQDVAGLVGGGGVSIYYSHTLKMLFFSYAQGKSFLAPLNTVEE SVKGSAMITLSSSSSQKEGGRSGKQGGAQSLCQWAEVPGHPGLVTAVMQVSNNPVVLMLT PNSIAVQEIKVVPAKAKITDMVAVRHWCGAGGEQKSTLILLCEDGSLRMYAASPEHTGXK XXXXPRPRLPPPPQPTPAPRRRPRALPHSSRKSHQATKSSAPGSPQFPIDFFEHCLTMTD IEFAGNDLLQVYNTAQIKHRLNTTGLYVVSTKMSGFTMEINNSDPNVVICGIRLLLGSQD VARTPSYVEIYGRSIPTIVVRSRWYDIPLTREESLQSDKKLTVVFGPSQDPDGVTMIDSV KVYGKNKEQFGWPEETEDSASCPSSSKIAQESEGGIGSWKPSPLERLACSALEALELGAV ATSAVGAEGAAEAAMRLLCAPASAQLHARAQCLLRNLHGSNYHQYKDQAILKYVYDTLVE LDATAEARNIDPEAYFRAVVLARSVAVTRPAHLVQAAPPAPPPPADGDWSIYWSAQDPSS PPHLVSLLVRVLRRLGACAAPAGGVLRPGLRHADTVLHALLDILHAATLHAQPHMVDFAN QIYLSLLLCEDQTISFGAKCALMRVLRPRVKRRRVYIPSPPNTPAGASTTTTTQPPASIT EVTSSEAEARDEQQESQFMDVDDPMEPIVLLAPDGGLEALLDIPPDADDETMVELAIALS LQEQAPASAPPPAPQAANVSPPQSDDEGSTAATDGSTPRPSPADAGGSAGSESGSGADSI GPGSGRSSAYGEMSAPAAGGIQATSSAPVPIPGPSTSSSSSTAARSHESDGSARKLHALR LSLLTAALDKIPTLKNYPGVRAIPFMQVILMLASDLDTAYDADRNVLERLLELLVAELDM NGEEAAKDVHLRTHQRELQLVAMRLLSVLMARWKNQGIPAGASRTEINQATSAAHVSRLA AMALVRAGAPAHCFNVLTALLPYWKEKGTNPGASPPGQQLLRPMPSQPLPDMQPFFVKEY VKGKGHALDVFDNYPQLLMEMALRLPCQIHKHCDPTTFDQRWRTLLADYMMNQQTPLRKQ VRKLLLLLCGTRERYRQLRDVHALDAHLQHARALAATPHPPYDQLVQLMEHLKACSEIVS ARTGNWQLACLSSRREALGWLVAVARRVHPHVAPPVLQLLQQALHPPTSSKPSSSSSEWG ERERSADSDAFVSDGSKFQEQRVPQLVQQILKQVSEDELRQFIKAFLLETNSTAVRWQAH SLLLAIYNNCSQADQANLVSLLWGIWPTLPQYGRKASQFVDLLGYFTLKTPNIDSEKYVA SAVDLLRSQNGLLARHGNAALYAALGSFVELDGYYLESEPCLVCNNPEVPMATIKLPTIK IDSKFTTTTQIVKLVSSHMISRISLRIGDIKRSKMVRTINFYYNNRTVQAVQELKNKPGM WHKAKRVQLQSGQSEVRVDFPLPIVACNLMMEYADFYENQQATGESLQCPRCSQLVPANP GVCANCGENVFQCHKCRAINYDEKDPFLCHACGFCKYAKFDYTLSARPCCAVDTIENDEE RKKMVQTIGALLDKADRVYRQLTANKPVLESLLHKISEHRVDRPCDEAPAPAVATAASFA GAQINRVIQSLAHKYCVDSRSHFEDLSKIIQKVLACRKELVSYDRMQSEQLKGDSVPVYA GLVQNYDGEVTKVNAVPESGGGCYGCSLACAEHCLTLLRALASQPEHRARLCRFGLVQEL VQHNLHRGTTQSQEEVRALICLVTRDNLPATEQLCTLLSQRVTLSLMGHAASPHHNNSCR CLDDYRTPVFIFERLCSIIYPEENDVAEFFLTLEKDPQQEDFLQGRMLGNPYSSLEVGMG PLMRDVKNKICTDCELVALLEDDNGMELLVCNKIMSLDLPVAEVYKKVWCTSGESVDAMR AVYRTRGLLGDATEEFVETLSQTNAEAVDHEQLYRMANVLADCGGIESMLSRLAAVQRVG AARALCSTLLRLLGLCTRVRRCVRVLTRADTRALPVLLHALHLAAAEEKDMPRAELVYQL LEIMERILSVAASETLESFLQFSLTFGGPEYVQALLNCTDIPSIRNNQEALGHLTRVLAA LVYGNDLKMAMLADHFKPVLDFDRLDSEWSEEEFRMELFCVLCANIERNSIGGTLKDYII SLGVVRDALDYIVKHAPCVKPTLVCTDSDELKEFIARPALKYILRFLTGLATDHEPTQML VCAEKVIPIVHRLEQVSSGEHVGSLAENLLEALRSQPQCAVKVQQVRDFTRQEKKRLAMA VRERQLGALGMRSNERGQVTAQCSLTQQVAELAEEHGAVCCICREGYKYQPTKVTISMYT IATSAGR NT seq 12084 nt NT seq  +upstreamnt  +downstreamnt atgcaacaaggtctaagcgcagtctgggtggcactgggcggtcgctgcctagcttggctc ggcgcgctattggccgacgcgaggcttgaagcgctgtcttcaggcacccccgtggccacg cccacccccgctccgccaatcatcttcgcgcagtacacggctcaccagcgagcccgccga ttggctgccgctgccccgctgcatcagttgctggtagccctagcggtcgtctcataccgc aaagccacagcgctaaagcgcgcagtggtacagaagcagcacgacgccgaccccgaccgc agcgactccaccgtctacttccacgacatgatcctgtgctccgaggactcggagactgat gacgacagcgagccgctgttcggtctctggttcgagtccacgctggtggctccggacgcg gcggagagcggcggcggcggcgccactgagcctgatgctgcgcccgcgcagcccgccctc gtgccggacaaggctgagccttattcttacatagcgctagccacggagatcttcacgctc ctcaccgcggagatcatcagcccgggcgcggagcggctcggcgcgtcggcgctgcagctg cacgactcgcacgtggcgctgctggcagccctggctaaagacctggatagggagacggct aggactgataccggcacaatatcctcgtgcttcggacctcgcctaggcgcgctctacagc cagttcagctcggctctagtccgctacctgcacaacctgagcggcgcgcccggcttcgcc tcgctgctgcccgcgctgcagcagcagctgctgaccgtgcccgccgacagcgcggctaat aagactccgctgcaggtggggccgcgcgtggtgaagctgctcggcagcatggtgctgtcc aagccggcggcggagagagagaactgcatcctgtccatgtggcacaagctggtgcacacg ctgcaggagtgcgcgctgcagccgcagccggcgcaggaccacgactacgaggatctgaat gtagagcacgcccaactgctggtgtacctgttccattctctgacgctgatgcagaagaag tcggtcctgcttatgacctctaatgccattatcaaggtggtagaaacattatcaatgagc gacaggaagcgagcagccaacgttctaccccaccagctgatgctgaccacccggctgatg ctcatactggagtacctcatgagacacttgtacgatgcaccacagtctctgcttcaacag atcgaatggaatctagtaatagcgccagggctggcgcaaccctcccccgaagccagcgca ggcgcagccggcagcaccaagcccaccaccgagggcgggcagctagcggcgcgtatctac tgctccgtgccgcatgtggaggctgcatacaggagactgacgcaggatgagagctccatg aggccgcggttttatgcgcttaccacggctgagattaataatcaggagaaccctaagttc gacggcctggcctgcaacttcgtgctcggcacccctcacaagctgaaatacccgttgcta ctggacgcgctgctagccctgcttaactccacgtgcgtttgtgacaaccctgcgcaggcg tcgtcgcccgccgcgctgacggcggcccattactgtttccagaccgcttggaggctagta gtaagcatgccgcccgccacgccgcacatggacaagctggcggcgggcacggcggcagat ctgcccgcgccgctgcctcttcacgcgctcatctgggcccctagagcggataacaagaag gtgttcaacccgtggctgaaggacgcgctggttaagcagggcatgtatacgcagtacgct gagaatctactagctggtgtgagcgcctcgtgcgacaacatcaagtacagcgcctggctc gcctctaagatcatcaagcatttgaaagagaacataacagcatccggcctccccgccctg ctggacgtgatatcgtgcgacgcggcgctggtgcggctgcacatctgcctcgccgacgcc gcgtccgccgccgaggcgcaccagttcatgccggacctgctggagctgctcgccacgttg gtggactgttgccgcataagcgccggcatggagctcgaatgcctgacagaaaccggggca tcggagtccgtagcagcagtcaacgcgacccggctactggtctgcggtaccctctgcccc attggtccgggggcggggccttcccccccgccggcgttgggggcgtggcttagagcgcag atgccggccaatgcctcacaagcattggatagactgtcggcgccaccgccgattcagtct aggaacactgcaatctacgcaaacgacatcatcccctccgagagtgccgtcctcaactta gtctcctcccactgcgagataatgagctgcggcggcgtgtactcggcgtgggcgtcgctg cgcatgctcggctactcggccgccaagctgctggaggcgggcgcgggcaagctggccgag gagcccgcgctggccgccgccgccggggacctcgtcgtgcccgcgctgacggacggccgc ctcgagttcatgtcggagcccctctcctgcacgctcacgacgctggtgccgcagcagctg aaggcggagcagctgatccacgagcacatcctgcgcaccacctaccccatgctggtggag catctgcagcccgccaccgagaagaccttgcgacatatggttaaatactgggagaagatt ctcgatcgacccgccggcagactcgcttacgaggtggtgttcgctgagggctccgagtat tccctcggaaagatcctcctctccgctccgaacgccaggaatccgtatgctgaacgagtt atcaaactgttcataaagatattcgccggatgcgagagctctgagctcagcagcgccctc tgcatctcggtgtgcaagttcctcggcgtcgcggataaggagaaggtggccagtctactg tcgcacatctgctttggaggaccagcggcgccaccgtcggcgggcacagccaacgccagc ccggtggagacggaactggccacgcccaccaccgccgcgcccgagcccaaccccgcctcg ctggcgctacgcaacgcgttgcggtcagtgttccggactgagcctactgatacaccatct ccagcgcctagaattcaatctgatacagcgcaaccatcaactaactctgataccggcagc tggtcggacgcgaagccggaggcggcggcggtgccggacgcgccggccgtgccgctctcc gacgccaccaacgacaacgcgctgctgctgacgcacctgtgcaagcacatcactatgcac tgcacggaggaagtcagcgagcgctgcctcgcactactcatctctgtctgcggcgacacc gcgcccgcgccgctgttgctcaaggagatgtgtcggttagccgacgctcacaacggacag gggcacaagcagctgttccaggcttgcgtcaaccagctgaatgtttgcgtggagcagctg agcagccaggaggtgctggagaagctggagtcgggcgcggcggacgcgggcgtggcgccg cagctggagtcgtgcggcgcgctgctggcctacctcgccgacgcgctgcacgccaccagc agcgcgcagccgcacacatggcgctctgtcagtcctacatgggagtctccgtccgacctc ggcttcgacttcgagtgcaccgacgaacagcaagacgatgacgacactagcgccgatgat tccgacgaagacgcgatgctccagtacaagctctgcactttcaccgtcacccaacgggag ttcatgaaccagcactggtaccactgccacacgtgcaagatggtggacggcgtgggcgtg tgcagcgtgtgcgctcgcgtgtgccacaagtcgcacgacgtgtcgtacgccaagttcggc aacttcttctgtgattgcggcgctaagaccgattcgagttgccaagcgctagtgaagcgc tcagcgacggccggcgcaggccgcgggggctcctcggacgagccgccccccgccccctcc ttgcgccgccgcccctccagccccgcgccctccgcgctgcccgcgccgccacgccgcccc gcgctcatacactttatacaaggctcccgccaatacctaagctcttaccccgagtggaca gcagtcactgagaaaatcggacgcctgctctccgccctatgcgggcctgtgcgcgcggcc tgcgagcgaggcgccgcggtgggcgcccacggccgggcccagagagcgctggcgcagctg catctgggggacaaacatatcaccagcacggataacttgatgctgcctacacttggtgtc acctcgccaggatcccaagagggcgcgttcgagaatgttcgcatgtcgtacacgggcgag aacgggcagacgatccgccagctgatgtcgtcgcacaagctgagacgggtagctatgtgc tgtctcgcttccccgcaggggaggaggcagcatctcgctgtcagccacgagaagggcaag ataaccgtgctgcagctatcagcattgctcaagcaagctgactcgtccaagcacaagtta accctgacgcgactgtcgtccgcgccgataccgttcaccgtgatcagtctgagcggcaac gcggccaatgaagacctgctagccgtttgcgggttgaaggagtgccatgtgctcacattc aatagcggtggagcggtatcagaccacctagttatcaacgcggatgtggaagcaactaac tacatcatcaaggcaatatggctgcccggctcgcagacgcagctggcgctcgtgacgtca gcgttcgtcaagatattcgacctgagcacggatctcaacaatccgatgcactacttcttg gtgcccagtggaaagatccgcgacgtgaccttcgtgaaccaagaaggcgagcagcagatg ctgtgcatgagctcggcgggccacatctactggcagccgatgagcgaggagtcgcgcgcc acgctcggcaccttctacgtcaccaacacgctggaggtgctgcaccctgagatacaggac gtggctgggctggttggcggcggcggagtgtccatttactactcgcacacgctgaagatg ctgttcttctcatacgcgcaagggaagagctttttggctccattgaacactgtcgaagag agtgttaaaggttcagcaatgataaccctatcctcatcatcgagccagaaggagggcggg cggtccggcaagcagggcggcgcgcagtcgctctgccagtgggcggaagtacccggacac ccggggctggtgaccgctgtcatgcaggtgtctaacaacccggtggtgttgatgctcacg cctaacagtatcgctgtgcaggagattaaggtggtcccagcaaaggctaagataaccgac atggtagcggtccgccactggtgcggcgcgggcggcgaacagaagagcacactcatactg ctctgtgaagacggcagtctgcgcatgtacgcggccagtcccgaacataccggctaaaag nnnnnnnnnnntccgcgaccgcgcctccccccccccccccagcccactcccgccccgcgg cgccgcccgagagcgctgccgcattctagcaggaagtcgcatcaggcaacgaagtcgagt gcccctggcagcccccagttcccgatcgacttcttcgagcactgcctcaccatgaccgac atcgagtttgccggcaacgacttgctgcaggtctacaacacggcgcagatcaaacacaga ctgaataccactggactatacgtggtttccacgaagatgagcggtttcactatggaaata aacaattcggatccgaacgtggtaatttgcggcatccgactgctgctcggcagtcaggat gtagccaggacaccgtcttatgttgagatatacgggcgctcaatccccacaatagtggtc cgcagccgctggtacgacatcccgctgacgcgcgaggagtcgctgcagtcggacaagaag cttaccgtcgtgttcggaccctcgcaggaccctgacggcgtcactatgattgattctgtc aaggtatacggaaagaacaaagagcaattcggatggcccgaagagacggaagactccgcg tcatgtccatcatctagcaagattgcacaagaatcggaaggcggcatcggctcatggaag cccagccctctcgaacgcctggcgtgctctgccctagaagctctggagttgggagcggtg gccacatcagctgttggggctgagggagccgctgaggcagccatgaggctgctgtgtgcg cccgcctcggctcagttgcatgcgcgtgcgcaatgcttgctgaggaacctacatggcagc aactatcatcaatacaaggaccaagcgatcctgaagtacgtgtacgacactctagtggag ctagacgcgacggcggaggctcgcaacatcgaccccgaggcgtacttccgcgccgtggtg ttagcgaggagtgtggccgtgacgcgccccgcgcacctcgtgcaggccgcgccgcccgcg ccgccgccgcccgctgacggcgactggtcaatctactggtccgcgcaagacccgtcctcc cccccgcacctggtgtccctgctggtgcgggtgctgcggcgcctgggggcgtgcgccgcg ccggcgggcggcgtgctgcggcccggcctgcgccacgccgacaccgtgctgcacgcgctg ctcgacatactgcacgccgccacgctgcacgcgcagccgcatatggtggactttgcaaac cagatctacctatcgctgttgctttgtgaagaccagaccatcagctttggagctaagtgt gcgttgatgagagtgcttcgacccagagtcaagaggcgtagggtctacattccttcgcca cctaatactccggcaggcgcgtcaacgacgacgaccacgcagccgccagcatccatcacg gaagtgacgtcatcggaggcggaggcgcgcgacgagcagcaggagagccagttcatggac gtggacgaccccatggagcccatcgtgctgctggctcccgacggcggtctagaagctcta ctagacattccgccagacgcggatgacgagacgatggtggagctcgccatcgctttatca ctacaggagcaagcgccggcctccgcgccgccgcctgcgccccaagctgctaatgtgtcg ccgccacagtcggacgacgagggcagcacggcggcgacggacggcagcacgccgcgcccg tcgcccgcggacgccggcggctcggccggctccgagagcggctccggcgccgacagcatc gggcccgggtccggccgcagcagcgcgtacggtgaaatgtctgccccagctgctggaggt attcaagcgacgagctctgcgcctgtccctattcctggtccatctacatcatccagcagc tcgacagccgctcgctcgcacgagtcggacggctcggcgcgcaagttgcacgcattacgg ctgtctctgctcacggccgcgctcgacaagatacccacgttgaagaattacccaggcgtc agggctataccgtttatgcaggtgatactaatgctagccagcgacctcgacacagcgtac gacgcggaccgcaacgtgctcgagcgcctactagagctgttagtggccgagctggacatg aacggggaggaggcggccaaggacgtgcacttgaggacccaccagagggagctgcagctc gtcgctatgaggctgttgagcgtcctaatggctcgctggaagaaccagggcatcccggcg ggggcgtcccgaacggagatcaaccaggccaccagcgccgcgcacgtgtcgcgcctcgcc gccatggcgctggtcagggccggcgcgcccgcgcactgcttcaacgtgttgacagccttg ctgccgtattggaaggagaagggaaccaacccgggagccagcccacctggccagcagttg ctgaggccgatgccctcacagccgctaccagatatgcagccgttctttgtcaaggaatat gtgaaaggtaaaggtcacgctctcgacgtgttcgacaactaccctcagttactcatggag atggcgctgcggctgccgtgccagatccacaagcactgcgacccgaccacgttcgaccag cgctggcggaccctgctggcggattatatgatgaaccagcagacgccgctcaggaagcaa gtccgcaaactgctccttctactctgcggcacgcgcgagcgctaccggcagctgcgcgac gtgcacgcgctggacgcgcacctgcagcacgcgcgcgcgctcgccgccacgccgcacccg ccctacgaccagctcgtgcagctcatggagcacctcaaggcgtgctcggagatcgtatca gctcgcacaggcaactggcaactggcgtgcctgagctcccggcgcgaggcgctcggctgg ctggtggcggtggcgcggcgcgtgcacccgcacgtggcgccccccgtgctgcagctgctg cagcaggcgctgcacccgcccacctccagcaagccgtcatcgtcgtcgtcggagtggggc gagcgcgagcgcagcgcggacagcgacgcgttcgtgtcggacggctccaagttccaggag cagcgcgtgccgcagctcgtgcagcagatacttaagcaggtatccgaagatgaacttcgg cagtttataaaggctttcctcctggagaccaactcgacagctgtgcgttggcaagcgcat tcactgctgctggctatttacaacaactgttcgcaagctgatcaagcgaatctggtatca ctgttgtggggtatatggccgacattacctcagtacggcaggaaggcttcgcaattcgtc gatctactcggttacttcactctcaagactcccaacatcgactctgagaagtacgtagcg agcgctgtagacctgctccgcagccagaacgggctcctagcacggcacgggaacgcggcg ctgtacgcggcactcggctcgttcgtggagctggacggctactacctcgagtcggagccg tgcctcgtgtgcaacaaccctgaggtgcccatggccaccatcaagctgcccaccatcaag atcgactccaaattcaccacaaccacgcaaatagtgaaactcgtgagcagccacatgatc agccgcatcagcctgcgcatcggcgacatcaagcgcagcaagatggtgcgcaccatcaac ttctactacaacaaccgcaccgtgcaggcggtccaggagctcaagaataaaccgggcatg tggcacaaagcgaagcgcgtgcagctgcaatccggccaatcagaagtccgcgtcgacttc ccgctgccaattgtcgcttgcaacctcatgatggagtatgcagacttctatgagaaccaa caggctactggcgagtcgctgcagtgcccgcgctgctcgcagctggtgcccgccaacccg ggcgtgtgcgccaactgcggcgagaacgtgttccagtgccacaagtgtcgcgcaataaac tacgacgagaaggacccgttcctgtgccacgcgtgcgggttctgcaagtacgccaagttc gactacacgctgtcagctcgaccatgctgcgccgtcgacaccatagagaacgatgaagag aggaagaagatggtgcagactataggcgcgctgctggacaaggcggatagggtttacagg cagctgactgctaacaagcctgttttggagtcgctgctacacaagataagcgagcaccga gtggaccgtccgtgcgacgaggcgccggccccggcggtcgccacggcggcctcgttcgcc ggcgcgcagatcaaccgcgtcatacagtcgttggcgcacaagtactgtgtggatagtcgc agccatttcgaggatttgtccaagatcatacagaaggttttggcttgcaggaaagaacta gtgtcatacgaccgcatgcagagtgagcagctcaagggtgactcggtgccggtctacgcc ggcctagtacagaactacgacggagaagtcactaaagtaaacgctgttccagagtccggc ggcggctgctacggctgctccttagcctgcgctgaacactgcctgaccctactgcgggca ctcgcctcgcagcccgagcaccgcgcgcgcctgtgccgcttcggcctggtgcaggagctg gtgcagcacaacctgcaccgcggcaccacgcagagtcaagaggaggtgcgcgcgctgatc tgcctggtgacgcgcgacaacctaccggccacggagcagctgtgcacgctgctctcccag cgcgtcacgctgtcgctcatgggccacgccgcctcgccccaccacaacaactcgtgtaga tgtctagacgactaccgcacgcccgtgttcatcttcgagcggctctgctcgattatatat ccggaggagaacgacgtggccgagttcttcctcacgctggagaaggacccgcagcaggag gactttttgcagggccgcatgttgggcaacccgtactcttccctcgaagtcggcatgggc ccactcatgcgcgacgtgaagaacaagatctgcacggattgcgagctggtggcgctgcta gaagacgacaatggcatggaactgctcgtgtgcaataagatcatgtcgctggatctgccg gttgctgaggtttataagaaggtgtggtgcacatcgggcgagagcgtggacgcgatgcgc gccgtgtaccgcacgcgcgggctgctcggggacgccaccgaggagtttgtggagacactc tcgcagaccaacgcggaggccgtggaccacgagcagctgtaccgcatggccaacgtgctg gccgactgtggaggcatcgaatccatgctgtcccgcctagccgcagtgcagcgcgtggga gcagcacgggcgctctgctcgaccctcctccggctgctgggcctctgcacgcgcgtgcgc cgctgcgtgcgcgtgctcacgcgggccgacacgcgcgcgctgcccgtgctgctgcacgcg ctgcatctcgctgctgccgaggagaaggacatgccgagggcggagctggtgtatcagctg cttgagataatggagcgcatactatccgtggctgcgagcgagaccctggagtcgttcctg cagttctcactaacgttcggaggacctgaatacgtgcaggcgctactcaactgcaccgac ataccgagcatccgcaacaaccaggaagccctaggccacctgacccgcgtcctagcagcc ttagtctacggcaacgacctcaagatggcgatgttagcggaccacttcaagccagttcta gacttcgaccggctcgactcagagtggagcgaagaggagttccgtatggagctgttctgt gttctctgcgcgaatatcgagaggaactctattgggggcacgctgaaggactacatcata tcgctgggcgtggtcagggatgcgctggattatattgtgaaacacgcgccctgtgtgaag ccaaccctcgtgtgcacggactcggacgagctgaaggagttcatcgcgcggccggcgctc aagtacatcctgcgcttcctcaccgggctcgccacggaccacgagcccacgcagatgcta gtgtgcgctgagaaggtgatccccatagtgcaccgcctggaacaagtgtcttctggagaa cacgtggggtccttagcggagaaccttctagaagctctgcgctctcaaccgcagtgtgcg gtgaaggtgcaacaagtcagggacttcaccagacaggagaagaaacgcctagccatggcg gtgcgcgagcggcaactgggcgcgctgggcatgcgcagcaacgagcgcgggcaggtgacg gcgcagtgctcgctcacgcagcaggtggccgagctggcggaggagcacggcgccgtctgc tgcatctgccgcgaggggtacaagtaccagcccaccaaggtgactatatctatgtatact atagcaacgagcgcgggcaggtga

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